A novel aptamer targeting TGF-β receptor II inhibits transdifferentiation of human tenon's fibroblasts into myofibroblast

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 11, 2012, Pages 6897-6903

  Zhu, Xiaoyan ^a   Li, Lei ^a   Zou, Lingyun ^a   Zhu, Xudong ^a   Xian, Guangjun ^a   Li, Haijun ^a   Tan, Yan ^a   Xie, Lin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ALPHA SMOOTH MUSCLE ACTIN; APTAMER; COLLAGEN GEL; PYROXYLIN; SINGLE STRANDED DNA; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; ACTA2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SMAD2 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CELL TRANSDIFFERENTIATION; CLINICAL ARTICLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RADIOACTIVITY; SCREENING; SIGNAL TRANSDUCTION; TENON CAPSULE; WESTERN BLOTTING; CELL CULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; DNA SEQUENCE; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; RADIOIMMUNOASSAY;

ACTINS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BLOTTING, WESTERN; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; DNA, SINGLE-STRANDED; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MYOFIBROBLASTS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; RADIOIMMUNOASSAY; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SELEX APTAMER TECHNIQUE; SEQUENCE ANALYSIS, DNA; SMAD2 PROTEIN; TENON CAPSULE; TRANSFORMING GROWTH FACTOR BETA;

EID: 84872049748     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-10198     Document Type: Article

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