메뉴 건너뛰기




Volumn 18, Issue 18, 1999, Pages 5073-5084

New mode of DNA binding of multi-zinc finger transcription factors: δEF1 family members bind with two hands to two target sites

Author keywords

EF1; Smad proteins; Smad interacting protein; Transgenic Xenopus; Two handed zinc finger proteins

Indexed keywords

DNA BINDING PROTEIN; INTEGRIN; TRANSCRIPTION FACTOR; UVOMORULIN; ZINC FINGER PROTEIN;

EID: 0033568198     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/18.18.5073     Document Type: Article
Times cited : (240)

References (36)
  • 1
    • 0029072998 scopus 로고
    • The Drosophila Schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family
    • Arora, K., Dai, H., Kazuko, S.G., Jamal, J., O'Connor, M.B., Letsou, A. and Warrior, R. (1995) The Drosophila Schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell, 81, 781-790.
    • (1995) Cell , vol.81 , pp. 781-790
    • Arora, K.1    Dai, H.2    Kazuko, S.G.3    Jamal, J.4    O'Connor, M.B.5    Letsou, A.6    Warrior, R.7
  • 3
    • 0027980532 scopus 로고
    • Transcriptional regulation of the human E-cadherin gene in human prostate cancer cell lines: Characterization of the human E-cadherin gene promoter
    • Bussemakers, M.J., Giroldi, L.A., Van Bokhoven, A. and Schalken, J.A. (1994) Transcriptional regulation of the human E-cadherin gene in human prostate cancer cell lines: characterization of the human E-cadherin gene promoter. Biochem. Biophys. Res. Commun., 203, 1284-1290.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1284-1290
    • Bussemakers, M.J.1    Giroldi, L.A.2    Van Bokhoven, A.3    Schalken, J.A.4
  • 4
    • 0025361913 scopus 로고
    • Transcriptional activation by TGF-β1 mediated by the dyad symmetry element (DSE) and the TPA responsive element (TRE)
    • De Groot, R.P. and Kruijer, W. (1990) Transcriptional activation by TGF-β1 mediated by the dyad symmetry element (DSE) and the TPA responsive element (TRE). Biochem. Biophys. Res. Commun., 168, 1074-1081.
    • (1990) Biochem. Biophys. Res. Commun. , vol.168 , pp. 1074-1081
    • De Groot, R.P.1    Kruijer, W.2
  • 5
    • 0025174698 scopus 로고
    • A DNA binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence
    • Fan, C.M. and Maniatis, T. (1990) A DNA binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence. Genes Dev., 4, 29-42.
    • (1990) Genes Dev. , vol.4 , pp. 29-42
    • Fan, C.M.1    Maniatis, T.2
  • 6
    • 0025812355 scopus 로고
    • The Drosophila zfh-1 and zfh-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs
    • Fortini, M.E., Lai, Z.C. and Rubin, G.M. (1991) The Drosophila zfh-1 and zfh-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs. Mech. Dev., 34, 113-122.
    • (1991) Mech. Dev. , vol.34 , pp. 113-122
    • Fortini, M.E.1    Lai, Z.C.2    Rubin, G.M.3
  • 7
    • 0027383025 scopus 로고
    • δ-crystallin enhancer binding protein δEF1 is a zinc finger-homeodomain protein implicated in postgastrulation embryogenesis
    • Funahashi, J., Sekido, R., Murai, K., Kamachi, Y. and Kondoh, H. (1993) δ-crystallin enhancer binding protein δEF1 is a zinc finger-homeodomain protein implicated in postgastrulation embryogenesis. Development, 119, 433-446.
    • (1993) Development , vol.119 , pp. 433-446
    • Funahashi, J.1    Sekido, R.2    Murai, K.3    Kamachi, Y.4    Kondoh, H.5
  • 8
    • 0028074197 scopus 로고
    • Displacement of an E-box binding repressor by basic helix-loop-helix proteins: Implications for B-cell specificity of the immunoglobulin heavy-chain enhancer
    • Genetta, T., Ruezinsky, D. and Kadesch, T. (1994) Displacement of an E-box binding repressor by basic helix-loop-helix proteins: implications for B-cell specificity of the immunoglobulin heavy-chain enhancer. Mol. Cell. Biol., 14, 6153-6163.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 6153-6163
    • Genetta, T.1    Ruezinsky, D.2    Kadesch, T.3
  • 9
    • 0028990126 scopus 로고
    • Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1
    • Grieder, N.C., Nellen, D., Burke, R., Basler, K. and Affolter, M. (1995) Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell, 81, 791-800.
    • (1995) Cell , vol.81 , pp. 791-800
    • Grieder, N.C.1    Nellen, D.2    Burke, R.3    Basler, K.4    Affolter, M.5
  • 10
    • 0032952931 scopus 로고    scopus 로고
    • Cell fate specification in the Drosophila salivary gland: The integration of homeotic gene function with the DPP signaling cascade
    • Henderson, K.D., Isaac, D.D. and Andrew, D.J. (1999) Cell fate specification in the Drosophila salivary gland: the integration of homeotic gene function with the DPP signaling cascade. Dev. Biol., 205, 10-21.
    • (1999) Dev. Biol. , vol.205 , pp. 10-21
    • Henderson, K.D.1    Isaac, D.D.2    Andrew, D.J.3
  • 12
    • 0028809646 scopus 로고
    • DNA binding through distinct domains of zinc-finger-homeodomain protein AREB6 has different effects on gene transcription
    • Ikeda, K. and Kawakami, K. (1995) DNA binding through distinct domains of zinc-finger-homeodomain protein AREB6 has different effects on gene transcription. Eur. J. Biochem., 233, 73-82.
    • (1995) Eur. J. Biochem. , vol.233 , pp. 73-82
    • Ikeda, K.1    Kawakami, K.2
  • 13
    • 17544365933 scopus 로고    scopus 로고
    • A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland
    • Jiang, Y., Yu, V.C., Buchholz, F., O'Connell, S., Rhodes, S.J., Candeloro, C., Xia, Y.R., Lusis, A.J. and Rosenfeld, M.G. (1996) A novel family of Cys-Cys, His-Cys zinc finger transcription factors expressed in developing nervous system and pituitary gland. J. Biol. Chem., 271, 10723-10730.
    • (1996) J. Biol. Chem. , vol.271 , pp. 10723-10730
    • Jiang, Y.1    Yu, V.C.2    Buchholz, F.3    O'Connell, S.4    Rhodes, S.J.5    Candeloro, C.6    Xia, Y.R.7    Lusis, A.J.8    Rosenfeld, M.G.9
  • 14
    • 0026468183 scopus 로고
    • Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific gene
    • Kim, J.G. and Hudson, L.D. (1992) Novel member of the zinc finger superfamily: A C2-HC finger that recognizes a glia-specific gene. Mol. Cell. Biol., 12, 5632-5639.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 5632-5639
    • Kim, J.G.1    Hudson, L.D.2
  • 15
    • 0031911356 scopus 로고    scopus 로고
    • SMADs: Mediators and regulators of TGF-β signaling
    • Kretzschmar, M. and Massagué, J. (1998) SMADs: mediators and regulators of TGF-β signaling. Curr. Opin. Genet. Dev., 8, 103-111.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 103-111
    • Kretzschmar, M.1    Massagué, J.2
  • 16
    • 0029806183 scopus 로고    scopus 로고
    • Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation
    • Kroll, K.L. and Amaya, L. (1996) Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development, 122, 3173-3183.
    • (1996) Development , vol.122 , pp. 3173-3183
    • Kroll, K.L.1    Amaya, L.2
  • 17
    • 0028107659 scopus 로고
    • Spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo
    • Kuhnlein, R.P., Frommer, G., Friedrich, M., Gonzalez-Gaitan, M., Weber, A., Wagner-Bernholz, J.F., Gehring, W.J., Jackle, H. and Schuh, R. (1994) Spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo. EMBO J., 13, 168-179.
    • (1994) EMBO J. , vol.13 , pp. 168-179
    • Kuhnlein, R.P.1    Frommer, G.2    Friedrich, M.3    Gonzalez-Gaitan, M.4    Weber, A.5    Wagner-Bernholz, J.F.6    Gehring, W.J.7    Jackle, H.8    Schuh, R.9
  • 19
    • 0030668506 scopus 로고    scopus 로고
    • The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins
    • Latinkic, B.V., Umbhauer, M., Neal, K.A., Lerchner, W., Smith, J.C. and Cunliffe, V. (1997) The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes Dev., 11, 3265-3276 [erratum in Genes Dev., 12, 1998, p. 1240].
    • (1997) Genes Dev. , vol.11 , pp. 3265-3276
    • Latinkic, B.V.1    Umbhauer, M.2    Neal, K.A.3    Lerchner, W.4    Smith, J.C.5    Cunliffe, V.6
  • 20
    • 0032522632 scopus 로고    scopus 로고
    • Latinkic, B.V., Umbhauer, M., Neal, K.A., Lerchner, W., Smith, J.C. and Cunliffe, V. (1997) The Xenopus Brachyury promoter is activated by FGF and low concentrations of activin and suppressed by high concentrations of activin and by paired-type homeodomain proteins. Genes Dev., 11, 3265-3276 [erratum in Genes Dev., 12, 1998, p. 1240].
    • (1998) Genes Dev. , vol.12 , pp. 1240
  • 23
    • 0031450875 scopus 로고    scopus 로고
    • The EVI1 gene in myeloid leukemia
    • Nucifora, G. (1997) The EVI1 gene in myeloid leukemia. Leukemia, 11, 2022-2031.
    • (1997) Leukemia , vol.11 , pp. 2022-2031
    • Nucifora, G.1
  • 24
    • 0030960196 scopus 로고    scopus 로고
    • ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation
    • Postigo, A.A. and Dean, D.C. (1997) ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation. EMBO J., 16, 3935-3943.
    • (1997) EMBO J. , vol.16 , pp. 3935-3943
    • Postigo, A.A.1    Dean, D.C.2
  • 25
    • 0026629862 scopus 로고
    • Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1
    • Ray, D., Bosselut, R., Ghysdael, J., Mattei, M.G., Tavitian, A. and Moreau-Gachelin, F. (1992) Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1. Mol. Cell. Biol., 12, 4297-4304.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4297-4304
    • Ray, D.1    Bosselut, R.2    Ghysdael, J.3    Mattei, M.G.4    Tavitian, A.5    Moreau-Gachelin, F.6
  • 26
    • 0028335394 scopus 로고
    • An intricate arrangement of binding sites for the Ets family of transcription factors regulates activity of the α4 integrin gene promoter
    • Rosen, G.D., Barks, J.L., Iademarco, M.F., Fisher, R.J. and Dean, D.C. (1994) An intricate arrangement of binding sites for the Ets family of transcription factors regulates activity of the α4 integrin gene promoter. J. Biol. Chem., 269, 15652-15660.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15652-15660
    • Rosen, G.D.1    Barks, J.L.2    Iademarco, M.F.3    Fisher, R.J.4    Dean, D.C.5
  • 27
    • 0028352113 scopus 로고
    • Xenopus embryos regulate the nuclear localization of XMyod
    • Rupp, R.A., Snider, L. and Weintraub, H. (1994) Xenopus embryos regulate the nuclear localization of XMyoD. Genes Dev., 8, 1311-1323.
    • (1994) Genes Dev. , vol.8 , pp. 1311-1323
    • Rupp, R.A.1    Snider, L.2    Weintraub, H.3
  • 28
    • 0028120915 scopus 로고
    • Transcription factor PRDII-BF1 activates human immunodeficiency virus type 1 gene expression
    • Seeler, J.S., Muchardt, C., Suessle, A. and Gaynor, R.B. (1994) Transcription factor PRDII-BF1 activates human immunodeficiency virus type 1 gene expression. J. Virol., 68, 1002-1009.
    • (1994) J. Virol. , vol.68 , pp. 1002-1009
    • Seeler, J.S.1    Muchardt, C.2    Suessle, A.3    Gaynor, R.B.4
  • 30
    • 0031307075 scopus 로고    scopus 로고
    • Two mechanisms in the action of repressor δEF1: Binding site competition with an activator and active repression
    • Sekido, R., Murai, K., Kamachi, Y. and Kondoh, H. (1997) Two mechanisms in the action of repressor δEF1: binding site competition with an activator and active repression. Genes Cells, 2, 771-783.
    • (1997) Genes Cells , vol.2 , pp. 771-783
    • Sekido, R.1    Murai, K.2    Kamachi, Y.3    Kondoh, H.4
  • 31
    • 0031594268 scopus 로고    scopus 로고
    • δEF1, a zinc finger and homeodomain-containing factor is required for normal skeleton patterning in multiple lineages
    • Takagi, T., Moribe, H., Kondoh, H. and Higashi, Y. (1998) δEF1, a zinc finger and homeodomain-containing factor is required for normal skeleton patterning in multiple lineages. Development, 125, 21-32.
    • (1998) Development , vol.125 , pp. 21-32
    • Takagi, T.1    Moribe, H.2    Kondoh, H.3    Higashi, Y.4
  • 32
    • 0026668883 scopus 로고
    • Structure and expression of major histocompatibility complex binding protein 2, a 275-kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class I genes
    • van't Veer, L.J., Lutz, P.M., Isselbacher, K.J. and Bernards, R. (1992) Structure and expression of major histocompatibility complex binding protein 2, a 275-kDa zinc finger protein that binds to an enhancer of major histocompatibility complex class I genes. Proc. Natl Acad. Sci. USA, 89, 8971-8975.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 8971-8975
    • Van't Veer, L.J.1    Lutz, P.M.2    Isselbacher, K.J.3    Bernards, R.4
  • 33
    • 0033575194 scopus 로고    scopus 로고
    • SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5′-CACCT sequences in candidate target genes
    • Verschueren, K. et al. (1999) SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5′-CACCT sequences in candidate target genes. J. Biol. Chem., 274, 20489-20498.
    • (1999) J. Biol. Chem. , vol.274 , pp. 20489-20498
    • Verschueren, K.1
  • 34
    • 0027761949 scopus 로고
    • Transcription factors positively and negatively regulating the Na,K-ATPase α1 subunit gene
    • Watanabe, Y., Kawakami, K., Hirayama, Y. and Nagano, K. (1993) Transcription factors positively and negatively regulating the Na,K-ATPase α1 subunit gene J. Biochem. (Tokyo), 114, 849-855.
    • (1993) J. Biochem. (Tokyo) , vol.114 , pp. 849-855
    • Watanabe, Y.1    Kawakami, K.2    Hirayama, Y.3    Nagano, K.4
  • 36
    • 0032570665 scopus 로고    scopus 로고
    • Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activity
    • Yee, K.S. and Yu, V.C. (1998) Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activity. J. Biol. Chem., 273, 5366-5374.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5366-5374
    • Yee, K.S.1    Yu, V.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.