Activation of a PGC-1-related coactivator (PRC)-dependent inflammatory stress program linked to apoptosis and premature senescence

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8004-8015

  Gleyzer, Natalie ^a   Scarpulla, Richard C ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE FUNCTIONS; ADAPTIVE RESPONSE; BIOLOGICAL RESPONSE; CELLULAR DYSFUNCTION; ENERGY METABOLISM; ISCHEMIA-REPERFUSION INJURY; MORPHOLOGICAL CHARACTERISTIC; PROTECTIVE EFFECTS;

BIOELECTRIC POTENTIALS; DRUG PRODUCTS; GENE EXPRESSION; METABOLISM;

CELL DEATH;

'PGC 1 RELATED COACTIVATOR; ACETYLCYSTEINE; BETA GALACTOSIDASE; FIRTECAN; LACTIC ACID; MECLOZINE; MENADIONE; MYC PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL PROTECTION; CELL STRESS; CELL STRUCTURE; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; GENE; GENE TARGETING; GLYCOLYSIS; HEART PROTECTION; HUMAN; HUMAN CELL; IL1ALPHA GENE; INFLAMMATION; METABOLIC STRESS; NEUROPROTECTION; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; SPRR2D GENE; SPRR2F GENE; TRANSCRIPTION INITIATION; TUMOR CELL;

ACETYLCYSTEINE; ANTIOXIDANTS; APOPTOSIS; CAMPTOTHECIN; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CELL AGING; CELL LINE, TUMOR; CELL SURVIVAL; CORNIFIED ENVELOPE PROLINE-RICH PROTEINS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; HISTAMINE H1 ANTAGONISTS; HUMANS; INFLAMMATION; KINETICS; MECLIZINE; OXIDANTS; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-MYC; PROTON IONOPHORES; RNA, SMALL INTERFERING; TOPOISOMERASE I INHIBITORS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; VITAMIN K 3;

EID: 84875442213     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.426841     Document Type: Article

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