Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS

FASEB Journal

Volumn 23, Issue 3, 2009, Pages 783-794

  Klimova, Tatyana A ^a   Bell, Eric L ^a   Shroff, Emelyn H ^a   Weinberg, Frank D ^a   Snyder, Colleen M ^a   Dimri, Goberdan P ^b,c   Schumacker, Paul T ^b   Scott Budinger, G R ^a   Chandel, Navdeep S ^a,b  

^a Department of Medicine ^*  (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c Evanston Northwestern Research Institute   (United States)

Author keywords

AMPK; Cell cycle; Telomerase

Indexed keywords

ADENYLATE KINASE; ALPHA TUBULIN; BMI1 PROTEIN; CATALASE; MANGANESE SUPEROXIDE DISMUTASE; MUTANT PROTEIN; PROTEIN E7; PROTEIN KINASE LKB1; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; SHORT HAIRPIN RNA;

ADULT; ARTICLE; CELL AGING; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HYPEROXIA; MITOCHONDRION; NORMAL HUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; TELOMERE;

EID: 61449220993     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-114256     Document Type: Article

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