Expression, Regulation, and Function of the SPR Family of Proteins: A Review

Cell Biochemistry and Biophysics

Volumn 30, Issue 2, 1999, Pages 243-265

  Tesfaigzi, Johannes ^a   Carlson, Don M ^b  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CORNIFINS; CYTOKINE; INTERMEDIATE FILAMENT PROTEIN; MEMBRANE PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN; RETINOID; SPRR2B PROTEIN, HUMAN; SPRR2D PROTEIN, HUMAN;

AGING; AMINO ACID SEQUENCE; ANIMAL; CELL COUNT; CELL CULTURE; CELL DIVISION; CHO CELL; CONSENSUS SEQUENCE; DIGESTIVE SYSTEM; EPIDERMIS; GENE EXPRESSION REGULATION; HAMSTER; HUMAN; LUNG TUMOR; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; PATHOLOGY; RESPIRATORY SYSTEM; REVIEW; SEQUENCE HOMOLOGY; SKIN; SKIN TUMOR; SQUAMOUS CELL CARCINOMA; TIME;

AGING; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CELL COUNT; CELL DIVISION; CHO CELLS; CONSENSUS SEQUENCE; CRICETINAE; CYTOKINES; DIGESTIVE SYSTEM; EPIDERMIS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERMEDIATE FILAMENT PROTEINS; LUNG NEOPLASMS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; NEOPLASMS, SQUAMOUS CELL; PROTEINS; RESPIRATORY SYSTEM; RETINOIDS; SEQUENCE HOMOLOGY, AMINO ACID; SKIN; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0032602126     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02738069     Document Type: Article

References (47)

1. An, G., Huang, T.H., Tesfaigzi, J., Garcia, H.J., Ledbetter, D.H., Carlson, D.M., and Wu, R. (1992) An unusual expression of a squamous cell marker, small proline-rich protein gene, in tracheobronchial epithelium, differential regulation and gene mapping. Am J Respir Cell Mol. Biol. 7(1), 104-111.
2. Gibbs, S., Fijneman, R., Wiegant, J., van Kessel, A.G., van De Putte, P., and Backendorf, C. (1993) Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins. Genomics 16(3), 630-637.
3. Mischke, D., Korge, B., Marenholz, I., Volz, A., and Ziegler, A. (1996) Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21. J. Invest Dermatol. 106(5), 989-992.
4. Backendorf, C., and Hohl, D. (1992) A common origin for cornified envelope proteins? [letter]. Nat. Genet. 2(2), 91.
5. Marvin, K.W., George, M.D., Fujimoto, W., Saunders, N.A., Bernacki, S.H., and Jetten, M.A. (1992) Cornifin, a cross-linked envelope precursor in keratinocytes that is down-regulated by retinoids. Proc Natl. Acad. Sci. USA 89, 11,026-11,030.
6. Austin, S.J., Fujimoto, W., Marvin, K.W., Vollberg, T.M., Lorand, L., and Jetten, A.M. (1996) Cloning and regulation of cornifin beta, a new member of the cornifin/spr family. Suppression by retinoic acid receptor-selective retinoids. J. Biol. Chem. 271(7), 3737-3742.
7. Kartasova, T. and van de Putte P. (1988) Isolation, characterization, and UV-stimulated expression of two families of genes encoding polypeptides of related structure in human epidermal keratinocytes. Mol. Cell Biol. 8(5), 2195-203.
8. Tesfaigzi, J., An, G., Wu, R., and Carlson, D.M. (1990) Induction in the expression of an unusual proline-rich protein by pig tracheal surface epithelial cells maintained in primary culture. Biochem Biophys. Res. Commun. 172(3), 1304-1309.
9. Smits, H.L., Floyd, E.E., and Jetten, A.M. (1987) Molecular cloning of gene sequences regulated during squamous differentiation of tracheal epithelial cells and controlled by retinoic acid. Mol. Cell Biol. 7(11), 4017-4023.
10. Koizumi, H., Kartasova, T., Tanaka, H., Ohkawara, A., and Kuroki, T. (1996) Differentiation-associated localization of small proline-rich protein in normal and diseased human skin. Br. J. Dermatol. 134(4), 686-692.
11. Hohl, D., de Viragh, P.A., Amiguet-Barras, F., Gibbs, S., Backendorf, C., and Huber, M. (1995) The small proline-rich proteins constitute a multigene family of differentially regulated cornified cell envelope precursor proteins. J. Invest. Dermatol. 104(6), 902-909.
12. Jarnik, M., Kartasova, T., Steinert, P., Lichti, U., and Steven, A. (1996) Differential expression and cell envelope incorporation of small proline-rich protein 1 in different cornified epithelia. J. Cell Sci. 109 (Pt 6), 1381-1391.
13. Kartasova, T., Darwiche, N., Kohno, Y., Koizumi, H., Osada, S., Huh, N., Lichti, U., Steinert, P.M., and Kuroki, T. (1996) Sequence and expression patterns of mouse SPR1, Correlation of expression with epithelial function. J. Invest. Dermatol. 106(2), 294-304.
14. Kartasova, T., van, M.G., van, P., Heerschap, H., and van de Putte, P. (1988) Novel protein in human epidermal keratinocytes, regulation of expression during differentiation. Mol. Cell Biol. 8(5), 2204-2210.
15. Owens, D.M., Zainal, T.A., Jetten, A.M., and Smart, R.C. (1996) Localization and expression of cornifin-alpha/SPRR1 in mouse epidermis, anagen hair follicles, and skin neoplasms. J. Invest. Dermatol. 106(4), 647-654.
16. Fujimoto, W., Nakanishi, G., Arata, J., and Jetten, A.M. (1997) Differential expression of human cornifin alpha and beta in squamous differentiating epithelial tissues and several skin lesions. J. Invest. Dermatol. 108(2), 200-204.
17. Fujimoto, W., Marvin, K.W., George, M.D., Celli, G., Darwiche, N., De Luca, L.M., and Jetten, A.M. (1993) Expression of cornifin in squamous differentiating epithelial tissues, including psoriatic and retinoic acid-treated skin. J. Invest. Dermatol. 101(3), 268-274.
18. Yaar, M., Eller, M.S., Bhawan, J., Harkness, D.D., DiBenedetto, P.J., and Gilchrest, B.A. (1995) In vivo and in vitro SPRR1 gene expression in normal and malignant keratinocytes. Exp. Cell. Res. 217(2), 217-226.
19. Abraham, J., Wang, S., Suzuki, H., Jiang, H., Rosenblum-Vos, L., Yin, J., and Meltzer, S. (1996) Esophagin cDNA cloning and characterization, a tissue-specific member of the small proline-rich protein family that is not expressed in esophageal tumors. Cell. Growth Differ. 7(7), 855-860.
20. Tesfaigzi, J., Th'ng, J., Wright, P.S., Hotchkiss, J.A., and Harkema, J.R. (1996) A small proline-rich protein, sPRR1, is up-regulated early during tobacco smoke-induced squamous metaplasia in rat nasal epithelia. Am. J. Respir. Cell Mol. Biol. 14, 478-486.
21. Tesfaigzi, J., Wright, P.S., Oreffo, V., An, G., Wu, R., Witschi, H., and Carlson, D.M. (1993) A small proline-rich protein regulated by vitamin A in tracheal epithelial cells is induced in lung tumors. Am J. Resp. Cell Mol. Biol. 9, 434-440.
22. Fornace, A.J. (1992) Mammalian genes induced by radiation; activation of genes associated with growth control. Annu. Rev. Genet. 26, 507-526.
23. Tesfaigzi, J., and Carlson, D.M. (1996) Cell cycle-specific expression of GOSPR in Chinese hamster ovary cells. Exp Cell Res 228, 277-282.
24. Fornace, A.J., Jr., Alamo, I., Jr., and Hollander, M.C. (1988) DNA damage-inducible transcripts in mammalian cells. Proc. Natl. Acad. Sci. USA 85(23), 8800-8804.
25. Fornace, A.J., Jr., Jackman, J., Hollander, M.C., Hoffman-Liebermann, B., and Liebermann, D.A. (1992) Genotoxic-stress-response genes and growth-arrest genes. gadd, MyD, and other genes induced by treatments eliciting growth arrest. Ann. NY Acad. Sci. 663, 139-153.
26. Ishida-Yamamoto, A., Kartasova, T., Matsuo, S., Kuroki, T., and Iizuka, H. (1997) Involucrin and SPRR are synthesized sequentially in differentiating cultured epidermal cells. J. Invest. Dermatol. 108(1), 12-16.
27. Lohman, F., Medema, J., Gibbs, S., Ponec, M., van, d.P.P., and Backendorf, C. (1997) Expression of the SPRR cornification genes is differentially affected by carcinogenic transformation. Exp. Cell Res. 231(1), 141-148.
28. Fischer, D.F., Gibbs, S., van De Putte, P., and Backendorf, C. (1996) Interdependent transcription control elements regulate the expression of the SPRR2A gene during keratinocyte terminal differentiation. Mol. Cell Biol. 16(10), 5365-5374.
29. Lohman, F.P., Gibbs, S., Fischer, D.F., Borgstein, A.M., van de Putte, P., and Backendorf, C. (1997) Involvement of c-JUN in the regulation of terminal differentiation genes in normal and malignant keratinocytes. Oncogene 14(13), 1623-1627.
30. An, G., Tesfaigzi, J., Chuu, Y.J., and Wu, R. (1993) Isolation and characterization of the human spr1 gene and its regulation of expression by phorbol ester and cyclic AMP. J. Biol. Chem. 268(15), 10,977-10,982.
31. Reddy, S.P., Chuu, Y.J., Lao, P.N., Donn, J., Ann, D.K., and Wu, R. (1995) Expression of human squamous cell differentiation marker, SPR1, in tracheobronchial epithelium depends on JUN and TRE motifs. J. Biol. Chem. 270(44), 26,451-26,459.
32. An, G., Tesfaigzi, J., Carlson, D.M., and Wu, R. (1993) Expression of a squamous cell marker, the spr1 gene, is posttranscriptionally down-regulated by retinol in airway epithelium. J. Cell Physiol. 157, 562-568.
33. Jetten, A.M., De Luca, L.M., Nelson, K., Schroeder, W., Burlingame, S., and Fujimoto, W. (1996) Regulation of cornifin alpha expression in the vaginal and uterine epithelium by estrogen and retinoic acid. Mol. Cell Endocrinol. 123(1), 7-15.
34. Gibbs, S., Backendorf, C., and Ponec, M. (1996) Regulation of keratinocyte proliferation and differentiation by all-trans-retinoic acid, 9-cis-retinoic acid and 1,25-dihydroxy vitamin D3. Arch. Dermatol. Res. 288(12), 729-738.
35. Tesfaigzi, J., and Carlson, D.M. (1996) Expression of the spr1 gene in cultured tracheal epithelial cells and its regulation by retinoids before and after confluence. J Cell Physiol 166(3), 480-486.
36. Saunders, N.A., and Jetten, A.M. (1994) Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon gamma. Antagonism by retinoic acid and transforming growth factor beta 1. J. Biol. Chem. 269(3), 2016-2022.
37. Lever, W.F., and Schaumburg-Lever, G. (1990) in Histopatholgoy of the Skin, 7th ed., Lippencott, Philadelphia, PA, pp. 523-577.
38. Steinert, P.M., and Marekov, L.N. (1995) The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope. J. Biol. Chem. 270(30), 17,702-17,711.
39. Roop, D. (1995) Defects in the barrier. Science 267(5197), 474-475.
40. Steven, A.C., and Steinert, P.M. (1994) Protein composition of cornified cell envelopes of epidermal kera tinocytes. J. Cell. Sci. 107(Pt 2), 693-700.
41. Baden, H., Kubilus, J., Phillips, S., Kvedar, J., and Tahan, S. (1987) A new class of soluble basic protein precursors of the cornified envelope of mammalian epidermis. Biochim. Biophys. Acta. 925(1), 63-73.
42. Greco, M.A., Lorand, L., Lane, W.S., Baden, H.P., Parameswaran, K.N., and Kvedar, J.C. (1995) The pancornulins, a group of small proline rich-related cornified envelope precursors with bifunctional capabilities in isopeptide bond formation. J. Invest. Dermatol. 104(2), 204-210.
43. Steinert, P.M. (1995) A model for the hierarchical structure of the human epidermal cornified cell envelope. Cell Death Diff. 2, 33-40.
44. Steinert, P.M., and Marekov, L.N. (1997) Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope. J. Biol. Chem. 272(3), 2021-2030.
45. Robinson, N.A., Lapic, S., Welter, J.F., and Eckert, R.L. (1997) S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. J. Biol. Chem. 272(18), 12,035-12,046.
46. Tesfaigzi, J., An, G., Wu, R., and Carlson, D.M. (1995) Two nuclear proteins in tracheal epithelial cells are recognized by antibodies specific to a squamous differentiation marker, spr1. J. Cell Physiol. 164, 571-578.
47. Zhan, Q., Lord, K.A., Alamo, I., Jr., Hollander, M.C., Carrier, F., Ron, D., Kohn, K.W., Hoffman, B., Liebermann, D.A., and Fornace, A.J., Jr. (1994) The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol. Cell Biol. 14(4), 2361-2371.