Carcinoma-associated fibroblasts are a promising therapeutic target

Cancers

Volumn 5, Issue 1, 2013, Pages 149-169

  Togo, Shinsaku ^a   Polanska, Urszula M ^b   Horimoto, Yoshiya ^a   Orimo, Akira ^a,b  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

CAF targeted cancer therapy; Carcinoma associated fibroblasts (CAFs); Innate drug resistance; Stromal tumour interaction; Tumour metastasis; Tumour microenvironment

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FAP PROTEIN; MEMBRANE PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; RAS PROTEIN; SCLEROPROTEIN; TENASCIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

CANCER INVASION; CARCINOMA ASSOCIATED FIBROBLAST; CELL ACTIVATION; CELL ACTIVITY; CELL MIGRATION; CELL POPULATION; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; FIBROBLAST; HETEROZYGOSITY LOSS; HUMAN; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; METASTASIS; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; TARGET CELL; TUMOR PROMOTION;

EID: 84875234222     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers5010149     Document Type: Review

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