Novel acylethanolamide derivatives that modulate body weight through enhancement of hypothalamic pro-opiomelanocortin (POMC) and/or decreased neuropeptide y (NPY)

Journal of Medicinal Chemistry

Volumn 56, Issue 5, 2013, Pages 1811-1829

  Avraham, Yosefa ^a   Katzhendler, Jehoshua ^b   Vorobeiv, Lia ^a   Merchavia, Shira ^a   Listman, Chana ^a   Kunkes, Eithan ^a   Harfoush, Fida' ^c   Salameh, Sawsan ^c   Ezra, Aviva F ^b   Grigoriadis, Nikolaos C ^d   Berry, Elliot M ^a   Najajreh, Yousef ^c  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c AL QUDS UNIVERSITY   (Palestine)

^d AHEPA UNIVERSITY HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; ANTIOBESITY AGENT; ASPARTATE AMINOTRANSFERASE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CHOLESTEROL; ELAIDOYL D VALINOLAMIDE; ELAIDOYL L VALINOLAMIDE; GLUCOSE; NEUROPEPTIDE Y; OLEOYL D VALINOLAMIDE; OLEOYL L VALINOLAMIDE; PALMITOYL L VALINOLAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROOPIOMELANOCORTIN; RIMONABANT; STEAROYL L VALINOLAMIDE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CARBON NUCLEAR MAGNETIC RESONANCE; CHOLESTEROL BLOOD LEVEL; CIRCULAR DICHROISM; COGNITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; DRUG STRUCTURE; FEMALE; FOOD INTAKE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; HISTOPATHOLOGY; HYPOTHALAMUS; LIPID DIET; LOCOMOTION; MOTOR ACTIVITY; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; OBESITY; PHYSICAL ACTIVITY; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; WEIGHT GAIN; WEIGHT REDUCTION;

AMIDES; ANIMALS; ANTI-OBESITY AGENTS; BODY WEIGHT; EATING; ETHANOLAMINES; FEMALE; HYPOTHALAMUS; MICE; MICE, INBRED C57BL; MICE, OBESE; NEUROPEPTIDE Y; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLEIC ACIDS; PRO-OPIOMELANOCORTIN; VALINE;

EID: 84875199116     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300484d     Document Type: Article

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