Mutant mouse models and antidepressant drug research: Focus on serotonin and brain-derived neurotrophic factor

Behavioural Pharmacology

Volumn 20, Issue 1, 2009, Pages 18-32

  Gardier, Alain M ^a,b  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b University of Paris XI   (France)

Author keywords

Antidepressant drugs; Anxiety; Brain derived neurotrophic factor; Depression; Knockout mouse; Serotonin receptors; Serotonin transporter

Indexed keywords

1 (4 AMINO 5 CHLORO 2 METHOXYPHENYL) 3 (1 BUTYL 4 PIPERIDINYL) 1 PROPANONE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CITALOPRAM; DESIPRAMINE; FENCLONINE; FLUOXETINE; IMIPRAMINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PAROXETINE; PINDOLOL; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B RECEPTOR; SEROTONIN 4 RECEPTOR; SEROTONIN AGONIST; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SEROTONIN 1 RECEPTOR;

ANXIETY; BEHAVIOR CHANGE; DEPRESSION; DOPAMINERGIC SYSTEM; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG RESEARCH; DRUG TARGETING; GASTROINTESTINAL SYMPTOM; GENE EXPRESSION; GENETIC MANIPULATION; HEART ATRIUM ARRHYTHMIA; HUMAN; MUTATIONAL ANALYSIS; NERVOUS SYSTEM DEVELOPMENT; NEUROTRANSMISSION; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN PROTEIN INTERACTION; REVIEW; SEROTONINERGIC SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; SLEEP DISORDER; TISSUE SPECIFICITY; UNSPECIFIED SIDE EFFECT; ADULT; ANIMAL; ANIMAL BEHAVIOR; ANIMAL MODEL; DISEASE MODEL; DRUG EFFECT; GENETIC POLYMORPHISM; GENETICS; METABOLISM; MOUSE; MOUSE MUTANT; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

ADULT; ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; POLYMORPHISM, GENETIC; RECEPTOR, TRKB; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RECEPTORS, SEROTONIN, 5-HT4; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 61449201295     PISSN: 09558810     EISSN: None     Source Type: Journal    
DOI: 10.1097/FBP.0b013e3283243fcd     Document Type: Review

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