The alternative medicine pawpaw and its acetogenin constituents suppress tumor angiogenesis via the HIF-1/VEGF pathway

Journal of Natural Products

Volumn 73, Issue 5, 2010, Pages 956-961

  Coothankandaswamy, Veena ^a   Liu, Yang ^a   Mao, Shui Chun ^a   Morgan, J Brian ^a   Mahdi, Fakhri ^a   Jekabsons, Mika B ^a   Nagle, Dale G ^a,b   Zhou, Yu Dong ^a  

^a Department of Pharmacognosy ^*  (United States)

^b Research Institute of Pharmaceutical Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

10 HYDROXYGLAUCANETIN; ACETOGENIN; ANNONACIN; ANNONACIN A; ANTINEOPLASTIC AGENT; ASIMINA TRILOBA EXTRACT; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLANT EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN;

ALTERNATIVE MEDICINE; ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASIMINA TRILOBA; CANCER CELL CULTURE; CARCINOGENESIS; CELL STRAIN T47D; CONTROLLED STUDY; DRUG MECHANISM; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; MEDICINAL PLANT; MITOCHONDRIAL RESPIRATION; NONHUMAN; TRADITIONAL MEDICINE;

ACETOGENINS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; ASIMINA; COMPLEMENTARY THERAPIES; DRUG SCREENING ASSAYS, ANTITUMOR; GLUCOSE TRANSPORTER TYPE 1; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PHYSIOLOGIC; PLANTS, MEDICINAL; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ASIMINA TRILOBA;

EID: 77953018205     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np100228d     Document Type: Article

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