Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1α activity

Biochemical and Biophysical Research Communications

Volumn 300, Issue 1, 2003, Pages 241-246

  Lee, You Mie ^a   Kim, Se Hee ^d   Kim, Hae Sun ^a,d   Son, Myung Jin ^a,d   Nakajima, Hidenori ^c   Kwon, Ho Jeong ^b   Kim, Kyu Won ^d  

^a Pusan National University   (South Korea)

^b Sejong University   (South Korea)

^c ASTELLAS PHARMA INC   (Japan)

^d Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

FR 901228; HISTONE DEACETYLASE INHIBITOR; HYPOXIA INDUCIBLE FACTOR 1; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HYPOXIA; LEWIS CARCINOMA; MALE; MOUSE; NONHUMAN; OXYGEN CONCENTRATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION;

ANIMALS; ANOXIA; ANTI-BACTERIAL AGENTS; DEPSIPEPTIDES; ENDOTHELIAL GROWTH FACTORS; ENZYME INHIBITORS; GENE EXPRESSION; HISTONE DEACETYLASES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; LYMPHOKINES; MALE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDES, CYCLIC; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0037225763     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02787-0     Document Type: Article

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