Phenanthroquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells

Journal of Natural Products

Volumn 69, Issue 7, 2006, Pages 1095-1097

  Cai, Xing Fu ^a   Jin, Xuejun ^a   Lee, Dongho ^a   Yang, Young Taek ^b   Lee, Kyeong ^a   Hong, Young Soo ^a   Lee, Jeong Hyung ^a   Lee, Jung Joon ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Jeju do Agricultural Research and Extension Services   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID DERIVATIVE; BOEHMERIA PANNOSA EXTRACT; CRYPTOPLEURINE; HERBACEOUS AGENT; HYDROXYCRYPTOPLEURINE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; METHANOL EXTRACTION RESIDUE; PHENANTHROQUINOLIZIDINE ALKALOID; PLANT EXTRACT; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; BIOASSAY; CANCER CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DETERMINATION; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; IC 50; NONHUMAN; PHYTOCHEMISTRY; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; RAMIE; REPORTER GENE; STOMACH CANCER;

ALKALOIDS; ANOXIA; BOEHMERIA; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INHIBITORY CONCENTRATION 50; KOREA; PLANT ROOTS; PLANTS, MEDICINAL; STOMACH NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

BOEHMERIA;

EID: 33747379469     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np060081y     Document Type: Article

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