Hirsutella sinensis mycelium suppresses interleukin-1β and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Huang, Tsung Teng ^a   Chong, Kowit Yu ^a   Ojcius, David M ^a,b   Wu, Yi Hui ^c   Ko, Yun Fei ^d,e   Wu, Cheng Yeu ^a   Martel, Jan ^a   Lu, Chia Chen ^f   Lai, Hsin Chih ^a   Young, John D ^a,d,e,g  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^d Chang Gung Medical Center   (Taiwan)

^e MING CHI UNIVERSITY OF TECHNOLOGY   (Taiwan)

^f FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^g ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALCOHOL; APOPTOSIS REGULATORY PROTEIN; CASPASE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NLRP1 PROTEIN, HUMAN; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X7 RECEPTOR; REACTIVE OXYGEN METABOLITE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; ASCOMYCETES; BIOLOGICAL MODEL; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; HUMAN; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MICROBIOLOGY; MYCELIUM; SECRETION (PROCESS);

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATE; APOPTOSIS REGULATORY PROTEINS; ASCOMYCOTA; CASPASES; DOWN-REGULATION; ENZYME ACTIVATION; ETHANOL; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MODELS, BIOLOGICAL; MYCELIUM; REACTIVE OXYGEN SPECIES; RECEPTORS, PURINERGIC P2X4; RECEPTORS, PURINERGIC P2X7;

EID: 84875127115     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01374     Document Type: Article

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