-
1
-
-
38349194472
-
Cell death in health and disease
-
Lockshin, R.A.; Zakeri, Z. Cell death in health and disease. J. Cell. Mol. Med. 2007, 11, 1214-1224.
-
(2007)
J. Cell. Mol. Med.
, vol.11
, pp. 1214-1224
-
-
Lockshin, R.A.1
Zakeri, Z.2
-
2
-
-
70349782208
-
Major cell death pathways at a glance
-
Duprez, L.; Wirawan, E.; Vanden Berghe, T.; Vandenabeele, P. Major cell death pathways at a glance. Microbes Infect. 2009, 11, 1050-1062.
-
(2009)
Microbes Infect.
, vol.11
, pp. 1050-1062
-
-
Duprez, L.1
Wirawan, E.2
Vanden Berghe, T.3
Vandenabeele, P.4
-
3
-
-
1442359848
-
The interplay between the Bcl-2 family and death receptor-mediated apoptosis
-
Sprick, M.R.; Walczak, H. The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochim. Biophys. Acta. 2004, 1644, 125-132.
-
(2004)
Biochim. Biophys. Acta.
, vol.1644
, pp. 125-132
-
-
Sprick, M.R.1
Walczak, H.2
-
4
-
-
77951901715
-
Cell death in the pathogenesis of heart disease: Mechanisms and significance
-
Whelan, R.S.; Kaplinskiy, V.; Kitsis, R.N. Cell death in the pathogenesis of heart disease: Mechanisms and significance. Annu. Rev. Physiol. 2010, 72, 19-44.
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 19-44
-
-
Whelan, R.S.1
Kaplinskiy, V.2
Kitsis, R.N.3
-
5
-
-
67749122122
-
Targeting PI3K signaling in cancer: Opportunities, challenges and limitations
-
Engelman, J.A. Targeting PI3K signaling in cancer: Opportunities, challenges and limitations. Nat. Rev. Cancer 2009, 9, 550-562.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 550-562
-
-
Engelman, J.A.1
-
6
-
-
77953131908
-
Targeting mitochondria for cancer therapy
-
Fulda, S.; Galluzzi, L.; Kroemer, G. Targeting mitochondria for cancer therapy. Nat. Rev. Drug Discov. 2010, 9, 447-464.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 447-464
-
-
Fulda, S.1
Galluzzi, L.2
Kroemer, G.3
-
7
-
-
36249002916
-
PKB and the mitochondria: AKT signaling on apoptosis
-
Parcellier, A.; Tintignac, L.A.; Zhuravleva, E.; Hemmings, B.A. PKB and the mitochondria: AKT signaling on apoptosis. Cell. Signal. 2008, 20, 21-30.
-
(2008)
Cell. Signal.
, vol.20
, pp. 21-30
-
-
Parcellier, A.1
Tintignac, L.A.2
Zhuravleva, E.3
Hemmings, B.A.4
-
8
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
Shaw, R.J.; Cantley, L.C. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature 2006, 441, 424-430.
-
(2006)
Nature
, vol.441
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
9
-
-
79960839035
-
Oncogenic AKT activation of translation as a therapeutic target
-
Hsieh A.C.; Truitt, M.L.; Ruggero, D. Oncogenic AKT activation of translation as a therapeutic target. Br. J. Cancer 2011, 105, 329-336.
-
(2011)
Br. J. Cancer
, vol.105
, pp. 329-336
-
-
Hsieh, A.C.1
Truitt, M.L.2
Ruggero, D.3
-
10
-
-
51849086880
-
PTEN: A new guardian of the genome
-
Yin, Y.; Shen, W.H. PTEN: A new guardian of the genome. Oncogene 2008, 27, 5443-5453.
-
(2008)
Oncogene
, vol.27
, pp. 5443-5453
-
-
Yin, Y.1
Shen, W.H.2
-
11
-
-
0035936023
-
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Baxc onformational change
-
Yamaguchi, H.; Wang, H.G. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Baxc onformational change. Oncogene 2001, 20, 7779-7786.
-
(2001)
Oncogene
, vol.20
, pp. 7779-7786
-
-
Yamaguchi, H.1
Wang, H.G.2
-
12
-
-
2442681877
-
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils
-
Gardai, S.J.; Hildeman, D.A.; Frankel, S.K.; Whitlock, B.B.; Frasch, S.C.; Borregaard, N.; Marrack, P.; Bratton, D.L.; Henson, P.M. Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J. Biol. Chem. 2004, 279, 21085-21095.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21085-21095
-
-
Gardai, S.J.1
Hildeman, D.A.2
Frankel, S.K.3
Whitlock, B.B.4
Frasch, S.C.5
Borregaard, N.6
Marrack, P.7
Bratton, D.L.8
Henson, P.M.9
-
13
-
-
33644865025
-
Evidence that Ser87 of Bim EL is phosphorylated by Akt and regulates BimEL apoptotic function
-
Qi, X.J.; Wildey, G.M.; Howe, P.H. Evidence that Ser87 of Bim EL is phosphorylated by Akt and regulates BimEL apoptotic function. J. Biol. Chem. 2006, 281, 813-823.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 813-823
-
-
Qi, X.J.1
Wildey, G.M.2
Howe, P.H.3
-
14
-
-
1242317030
-
Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
-
Dan, H.C.; Sun, M.; Kaneko, S.; Feldman, R.I.; Nicosia, S.V.; Wang, H.G.; Tsang, B.K.; Cheng, J.Q. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J. Biol. Chem. 2004, 279, 5405-5412.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5405-5412
-
-
Dan, H.C.1
Sun, M.2
Kaneko, S.3
Feldman, R.I.4
Nicosia, S.V.5
Wang, H.G.6
Tsang, B.K.7
Cheng, J.Q.8
-
15
-
-
33644855216
-
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
-
Maurer, U.; Charvet, C.; Wagman, A.S.; Dejardin, E.; Green, D.R. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol. Cell 2006, 21, 749-760.
-
(2006)
Mol. Cell
, vol.21
, pp. 749-760
-
-
Maurer, U.1
Charvet, C.2
Wagman, A.S.3
Dejardin, E.4
Green, D.R.5
-
16
-
-
2942726155
-
The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation
-
Van Der Heide, L.P.; Hoekman, M.F.M.; Smidt, M.P. The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation. Biochem. J. 2004, 380, 297-309.
-
(2004)
Biochem. J
, vol.380
, pp. 297-309
-
-
Van Der Heide, L.P.1
Hoekman, M.F.M.2
Smidt, M.P.3
-
17
-
-
79951887419
-
Forkhead boxo as a sensor, mediator and regulator of redox signaling
-
De Keizer, P.L.; Burgering, B.M.; Dansen, T.B. Forkhead boxo as a sensor, mediator and regulator of redox signaling. Antioxid. Redox Signal. 2011, 14, 1093-1106.
-
(2011)
Antioxid. Redox Signal
, vol.14
, pp. 1093-1106
-
-
de Keizer, P.L.1
Burgering, B.M.2
Dansen, T.B.3
-
18
-
-
0033517189
-
NF-kappa B activation by tumour necrosis factor requires the Akt serine-threonine kinase
-
Ozes, O.N.; Mayo, L.D.; Gustin, J.A.; Pfeffer, S.R.; Pfeffer, L.M.; Donner, D.B. NF-kappa B activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999, 401, 82-85.
-
(1999)
Nature
, vol.401
, pp. 82-85
-
-
Ozes, O.N.1
Mayo, L.D.2
Gustin, J.A.3
Pfeffer, S.R.4
Pfeffer, L.M.5
Donner, D.B.6
-
19
-
-
0033517190
-
NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
-
Romashkova, J.A.; Makarov, S.S. NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature 1999, 401, 86-90.
-
(1999)
Nature
, vol.401
, pp. 86-90
-
-
Romashkova, J.A.1
Makarov, S.S.2
-
20
-
-
79251602618
-
PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2proteins and enhanced mitochondrial apoptosis
-
Bender, A.; Opel, D.; Naumann, I.; Kappler, R.; Friedman, L.; von Schweinitz, D.; Debatin, K.M.; Fulda, S. PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2proteins and enhanced mitochondrial apoptosis. Oncogene 2011, 30, 494-503.
-
(2011)
Oncogene
, vol.30
, pp. 494-503
-
-
Bender, A.1
Opel, D.2
Naumann, I.3
Kappler, R.4
Friedman, L.5
von Schweinitz, D.6
Debatin, K.M.7
Fulda, S.8
-
21
-
-
79956017530
-
Targeting aberrant PI3K/Akt activation by PI 103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma
-
Opel, D.; Naumann, I.; Schneider, M.; Bertele, D.; Debatin, K.M.; Fulda, S. Targeting aberrant PI3K/Akt activation by PI 103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma. Clin. Cancer Res. 2011, 17, 3233-3247.
-
(2011)
Clin. Cancer Res
, vol.17
, pp. 3233-3247
-
-
Opel, D.1
Naumann, I.2
Schneider, M.3
Bertele, D.4
Debatin, K.M.5
Fulda, S.6
-
22
-
-
33847077943
-
FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells
-
Obexer, P.; Geiger, K.; Ambros, P.F.; Meister, B.; Ausserlechner, M.J. FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells. Cell Death Differ. 2007, 14, 534-547.
-
(2007)
Cell Death Differ
, vol.14
, pp. 534-547
-
-
Obexer, P.1
Geiger, K.2
Ambros, P.F.3
Meister, B.4
Ausserlechner, M.J.5
-
23
-
-
68149153007
-
Noxa: At the tip of the balance between life and death
-
Ploner, C.; Kofler, R.; Villunger, A. Noxa: At the tip of the balance between life and death. Oncogene 2008, 27, 84-92.
-
(2008)
Oncogene
, vol.27
, pp. 84-92
-
-
Ploner, C.1
Kofler, R.2
Villunger, A.3
-
24
-
-
0037169358
-
Apoptosis, a link between cancer genetics and chemotherapy
-
Johnstone, R.W.; Ruefli, A.A.; Lowe, S.W. Apoptosis, a link between cancer genetics and chemotherapy. Cell 2002, 108, 153-164.
-
(2002)
Cell
, vol.108
, pp. 153-164
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Lowe, S.W.3
-
25
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anti cancer chemotherapy
-
Fulda, S.; Debatin, K.M. Extrinsic versus intrinsic apoptosis pathways in anti cancer chemotherapy. Oncogene 2006, 25, 4798-4811.
-
(2006)
Oncogene
, vol.25
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.M.2
-
26
-
-
84856495152
-
Targeting IAP proteins for therapeutic intervention in cancer
-
Fulda, S.; Vucic, D. Targeting IAP proteins for therapeutic intervention in cancer. Nat. Rev. Drug Discov. 2012, 11, 109-124.
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 109-124
-
-
Fulda, S.1
Vucic, D.2
-
27
-
-
0030941458
-
P53, the cellular gatekeeper for growth and division
-
Levine, A. P53, the cellular gatekeeper for growth and division. Cell. Mol. Biol. 1997, 88, 323-331.
-
(1997)
Cell. Mol. Biol
, vol.88
, pp. 323-331
-
-
Levine, A.1
-
28
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
-
Yin, C.; Knudson, C.; Korsmeyer, S.; Dyke, T.V. Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 1997, 385, 637-640.
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.1
Knudson, C.2
Korsmeyer, S.3
Dyke, T.V.4
-
29
-
-
43749104681
-
Cell cycle checkpoint signaling, cell cycle arrest versus apoptosis
-
Pietenpol, J.; Stewart, Z. Cell cycle checkpoint signaling, cell cycle arrest versus apoptosis. Toxicology 2002, 475, 181-182.
-
(2002)
Toxicology
, vol.475
, pp. 181-182
-
-
Pietenpol, J.1
Stewart, Z.2
-
30
-
-
0029958381
-
Reactive oxygen species are downstream mediators of p53-dependent apoptosis
-
Johnson, T.; Yu, Z.; Ferrans, V.; Lowenstein, R.; Finkel, T. Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc. Natl. Acad. Sci. USA 1996, 93, 11848-11852.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11848-11852
-
-
Johnson, T.1
Yu, Z.2
Ferrans, V.3
Lowenstein, R.4
Finkel, T.5
-
31
-
-
0033961443
-
Role of p53 family members in apoptosis
-
Sheikh, M.; Fornace, A.J. Role of p53 family members in apoptosis. J. Cell. Physiol. 2000, 182, 171-181.
-
(2000)
J. Cell. Physiol
, vol.182
, pp. 171-181
-
-
Sheikh, M.1
Fornace, A.J.2
-
32
-
-
0036260697
-
Cellular response to oxidative stress, signaling for suicide and survival
-
Martindale, J.; Holbrook, N. Cellular response to oxidative stress, signaling for suicide and survival. J. Cell. Physiol. 2002, 192, 1-15.
-
(2002)
J. Cell. Physiol
, vol.192
, pp. 1-15
-
-
Martindale, J.1
Holbrook, N.2
-
33
-
-
2342471409
-
Toxic proteins released from mitochondria in cell death
-
Saelens, X.; Festjens, N.; Walle, L.V.; van Gurp, M.; van Loo, G.; Vandenabeele, P. Toxic proteins released from mitochondria in cell death. Oncogene 2004, 23, 2861-2874.
-
(2004)
Oncogene
, vol.23
, pp. 2861-2874
-
-
Saelens, X.1
Festjens, N.2
Walle, L.V.3
van Gurp, M.4
van Loo, G.5
Vandenabeele, P.6
-
34
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du, C.; Fang, M.; Li, Y.; Li, L.; Wang, X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000, 102, 33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
35
-
-
18244386261
-
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
-
Van Loo, G.; van Gurp, M.; Depuydt, B.; Srinivasula, S.M.; Rodriguez, I.; Alnemri, E.S.; Gevaert, K.; Vandekerckhove, J.; Declercq, W.; Vandenabeele, P. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. Cell Death Differ. 2002, 9, 20-26.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 20-26
-
-
van Loo, G.1
van Gurp, M.2
Depuydt, B.3
Srinivasula, S.M.4
Rodriguez, I.5
Alnemri, E.S.6
Gevaert, K.7
Vandekerckhove, J.8
Declercq, W.9
Vandenabeele, P.10
-
36
-
-
33746298246
-
Mechanisms of cytochrome c release from mitochondria
-
Garrido, C.; Galluzzi, L.; Brunet, M.; Puig, P.E.; Didelot, C.; Kroemer, G. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ. 2006, 13, 1423-1433.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1423-1433
-
-
Garrido, C.1
Galluzzi, L.2
Brunet, M.3
Puig, P.E.4
Didelot, C.5
Kroemer, G.6
-
37
-
-
0033107657
-
The apoptosome, heart and soul of the cell death machine
-
Chinnaiyan, A.M. The apoptosome, heart and soul of the cell death machine. Neoplasia 1999, 1, 5-15.
-
(1999)
Neoplasia
, vol.1
, pp. 5-15
-
-
Chinnaiyan, A.M.1
-
38
-
-
2942532135
-
Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes
-
Hill, M.M.; Adrain, C.; Duriez, P.J.; Creagh, E.M.; Martin, S.J. Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes. EMBO J. 2002, 23, 2134-2145.
-
(2002)
EMBO J.
, vol.23
, pp. 2134-2145
-
-
Hill, M.M.1
Adrain, C.2
Duriez, P.J.3
Creagh, E.M.4
Martin, S.J.5
-
39
-
-
5644259587
-
Inhibitor of apoptosis proteins, translating basic knowledge into clinical practice
-
Schimmer, A.D. Inhibitor of apoptosis proteins, translating basic knowledge into clinical practice. Cancer Res. 2004, 64, 7183-7190.
-
(2004)
Cancer Res.
, vol.64
, pp. 7183-7190
-
-
Schimmer, A.D.1
-
40
-
-
27544471076
-
The mitochondrial death squad, hardened killers or innocent bystanders?
-
Ekert, P.G.; Vaux, D.L. The mitochondrial death squad, hardened killers or innocent bystanders? Curr. Opin. Cell Biol. 2005, 17, 626-630.
-
(2005)
Curr. Opin. Cell Biol.
, vol.17
, pp. 626-630
-
-
Ekert, P.G.1
Vaux, D.L.2
-
41
-
-
0035967169
-
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death
-
Joza, N.; Susin, S.A.; Daugas, E.; Stanford, W.L.; Cho, S.K.; Li, C.Y.; Sasaki T.; Elia, A.J.; Cheng, H.Y.M.; Ravagnan, L.; et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 2001, 410, 549-554.
-
(2001)
Nature
, vol.410
, pp. 549-554
-
-
Joza, N.1
Susin, S.A.2
Daugas, E.3
Stanford, W.L.4
Cho, S.K.5
Li, C.Y.6
Sasaki, T.7
Elia, A.J.8
Cheng, H.Y.M.9
Ravagnan, L.10
-
42
-
-
0034698733
-
Two distinct pathways leading to nuclear apoptosis
-
Susin, S.A.; Daugas, E.; Ravagnan, L.; Samejima, K.; Zamzami, N.; Loeffler, M.; Costantini, P.; Ferri, K.F.; Irinopoulou, T.; Prévost, M.-C.; et al. Two distinct pathways leading to nuclear apoptosis. J. Exp. Med. 2000, 192, 571-580.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 571-580
-
-
Susin, S.A.1
Daugas, E.2
Ravagnan, L.3
Samejima, K.4
Zamzami, N.5
Loeffler, M.6
Costantini, P.7
Ferri, K.F.8
Irinopoulou, T.9
Prévost, M.-C.10
-
43
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li, L.Y.; Luo, X.; Wang, X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 2001, 412, 95-99.
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
44
-
-
0031888955
-
A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD
-
Enari, M.; Sakahira, H.; Yokoyama, H.; Okawa, K.; Iwamatsu, A.; Nagata, S. A caspase-activated DNase that degrades DNA during apoptosis and its inhibitor ICAD. Nature 1998, 391, 43-50.
-
(1998)
Nature
, vol.391
, pp. 43-50
-
-
Enari, M.1
Sakahira, H.2
Yokoyama, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
45
-
-
0036716281
-
The Bcl2 family, regulators of the cellular life-or-death switch
-
Cory, S.; Adams, J.M. The Bcl2 family, regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2002, 2, 647-656.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
46
-
-
0035206383
-
Mechanisms of p53-dependent apoptosis
-
Schuler, M.; Green, D.R. Mechanisms of p53-dependent apoptosis. Biochem. Soc. Trans. 2001, 29, 684-688.
-
(2001)
Biochem. Soc. Trans.
, vol.29
, pp. 684-688
-
-
Schuler, M.1
Green, D.R.2
-
47
-
-
0023786047
-
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
-
Vaux, D.L.; Cory, S.; Adamsm, J.M. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988, 335, 440-442.
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adamsm, J.M.3
-
48
-
-
84872075127
-
Targeting the anti-apoptotic bcl-2 family members for the treatment of cancer
-
Weyhenmeyer, B.; Murphy, A.C.; Prehn, J.H.; Murphy, B.M. Targeting the anti-apoptotic bcl-2 family members for the treatment of cancer. Exp. Oncol. 2012, 34, 192-199.
-
(2012)
Exp. Oncol
, vol.34
, pp. 192-199
-
-
Weyhenmeyer, B.1
Murphy, A.C.2
Prehn, J.H.3
Murphy, B.M.4
-
49
-
-
0021679848
-
Cloning of the chromosome breakpoint of neoplastic B cells with the t (14;18) chromosome translocation
-
Tsujimoto, Y.; Finger, L.R.; Yunis, J.; Nowell, P.C.; Croce, C.M. Cloning of the chromosome breakpoint of neoplastic B cells with the t (14;18) chromosome translocation. Science 1984, 226, 1097-1099.
-
(1984)
Science
, vol.226
, pp. 1097-1099
-
-
Tsujimoto, Y.1
Finger, L.R.2
Yunis, J.3
Nowell, P.C.4
Croce, C.M.5
-
50
-
-
0031464448
-
Bcl-2 family proteins, regulators of apoptosis and chemoresistance in hematologic malignancies
-
Reed, J.C. Bcl-2 family proteins, regulators of apoptosis and chemoresistance in hematologic malignancies. Semin. Hematol. 1997, 34, 9-19.
-
(1997)
Semin. Hematol.
, vol.34
, pp. 9-19
-
-
Reed, J.C.1
-
51
-
-
78650782391
-
Anti-apoptosis and cell survival: A review
-
Portt, L.; Norman, G.; Clapp, C.; Greenwood, M.; Greenwood, T.M. Anti-apoptosis and cell survival: A review. Biochim. Biophys. Acta 2011, 1813, 238-259.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 238-259
-
-
Portt, L.1
Norman, G.2
Clapp, C.3
Greenwood, M.4
Greenwood, T.M.5
-
52
-
-
0028040019
-
Bcl-2 and the regulation of programmed cell death
-
Reed, J.C. Bcl-2 and the regulation of programmed cell death. J. Cell. Biol. 1994, 124, 1-6.
-
(1994)
J. Cell. Biol
, vol.124
, pp. 1-6
-
-
Reed, J.C.1
-
53
-
-
54949132875
-
Bcl-2 family proteins and cancer
-
Yip, K.W.; Reed J.C. Bcl-2 family proteins and cancer. Oncogene 2008, 27, 6398-6406.
-
(2008)
Oncogene
, vol.27
, pp. 6398-6406
-
-
Yip, K.W.1
Reed, J.C.2
-
54
-
-
0037427412
-
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members
-
Scorrano, L.; Korsmeyer, S. Mechanisms of cytochrome c release by proapoptotic BCL-2 family members. Biochem. Biophys. Res. Commun. 2003, 304, 437-444.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 437-444
-
-
Scorrano, L.1
Korsmeyer, S.2
-
55
-
-
0028956550
-
Regulators of cell death
-
Korsmeyer, S.J. Regulators of cell death. Trends Genet. 1995, 11, 101-105.
-
(1995)
Trends Genet.
, vol.11
, pp. 101-105
-
-
Korsmeyer, S.J.1
-
56
-
-
52149124141
-
Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis
-
Lee, H.J.; Lee, H.J.; Lee, E.O.; Ko, S.G.; Bae, H.S.; Kim, C.H.; Ahn, K.S.; Lu, J.; Kim, S.H. Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis. Cancer Lett. 2008, 207, 342-353.
-
(2008)
Cancer Lett
, vol.207
, pp. 342-353
-
-
Lee, H.J.1
Lee, H.J.2
Lee, E.O.3
Ko, S.G.4
Bae, H.S.5
Kim, C.H.6
Ahn, K.S.7
Lu, J.8
Kim, S.H.9
-
57
-
-
84872445303
-
Caspase control: Protagonists of cancer cell apoptosis
-
Fiandalo, M.V.; Kyprianou, N. Caspase control: Protagonists of cancer cell apoptosis. Exp. Oncol. 2012, 34, 165-175.
-
(2012)
Exp. Oncol.
, vol.34
, pp. 165-175
-
-
Fiandalo, M.V.1
Kyprianou, N.2
-
58
-
-
0038786580
-
Apoptosis-targeted therapies for cancer
-
Reed, J. Apoptosis-targeted therapies for cancer. Cancer Cell 2003, 3, 9-17.
-
(2003)
Cancer Cell
, vol.3
, pp. 9-17
-
-
Reed, J.1
-
59
-
-
0035968303
-
A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains
-
Zapata, J.M.; Pawlowski, K.; Haas, E.; Ware, C.F.; Godzik, A.; Reed, J.C. A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains. J. Biol. Chem. 2001, 276, 24242-24252.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24242-24252
-
-
Zapata, J.M.1
Pawlowski, K.2
Haas, E.3
Ware, C.F.4
Godzik, A.5
Reed, J.C.6
-
60
-
-
0038541842
-
Dysregulation of CD95/CD95 ligand-apoptotic pathway in CD3 large granular lymphocyte leukemia
-
Lamy, T.; Liu, J.H.; Landowski, T.H.; Dalton, W.S.; Loughran, T.P., Jr. Dysregulation of CD95/CD95 ligand-apoptotic pathway in CD3 large granular lymphocyte leukemia. Blood 1998, 92, 4771-4777.
-
(1998)
Blood
, vol.92
, pp. 4771-4777
-
-
Lamy, T.1
Liu, J.H.2
Landowski, T.H.3
Dalton, W.S.4
Loughran Jr., T.P.5
-
61
-
-
0034856368
-
CD95 antigen mutations in hematopoietic malignancies
-
Landowski, T.H.; Moscinski, L.; Burke, R.; Buyuksal, I.; Painter, J.S.; Goldstein, S.; Dalton, W.S. CD95 antigen mutations in hematopoietic malignancies. Leuk. Lymphoma 2001, 42, 835-846.
-
(2001)
Leuk. Lymphoma
, vol.42
, pp. 835-846
-
-
Landowski, T.H.1
Moscinski, L.2
Burke, R.3
Buyuksal, I.4
Painter, J.S.5
Goldstein, S.6
Dalton, W.S.7
-
62
-
-
0034641898
-
CD95's deadly mission in the immune system
-
Krammer, P.H. CD95's deadly mission in the immune system. Nature 2000, 407, 789-795.
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
63
-
-
0037204952
-
The Fas signaling pathway, more than a paradigm
-
Wajant, H. The Fas signaling pathway, more than a paradigm. Science 2002, 296, 1635-1636.
-
(2002)
Science
, vol.296
, pp. 1635-1636
-
-
Wajant, H.1
-
64
-
-
0030715354
-
Mutations in the Fas antigen in patients with multiple myeloma
-
Landowski, T.H.; Qu, N.; Buyuksal, I.; Painter, J.S.; Dalton, W.S. Mutations in the Fas antigen in patients with multiple myeloma. Blood 1997, 90, 4266-4270.
-
(1997)
Blood
, vol.90
, pp. 4266-4270
-
-
Landowski, T.H.1
Qu, N.2
Buyuksal, I.3
Painter, J.S.4
Dalton, W.S.5
-
65
-
-
0034881027
-
Identification of two Fas-associated phosphatase-1 (FAP-1) promoters in human cancer cells
-
Irie, S.; Li, Y.; Kanki, H.; Ohyama, T.; Deaven, L.L.; Somlo, S.; Sato, T.A. Identification of two Fas-associated phosphatase-1 (FAP-1) promoters in human cancer cells. DNA Seq. 2001, 11, 519-526.
-
(2001)
DNA Seq
, vol.11
, pp. 519-526
-
-
Irie, S.1
Li, Y.2
Kanki, H.3
Ohyama, T.4
Deaven, L.L.5
Somlo, S.6
Sato, T.A.7
-
66
-
-
0035192884
-
FLICE-inhibitory proteins, regulators of death receptor-mediated apoptosis
-
Krueger, A.; Baumann, S.; Krammer, P.H.; Kirchhoff, S. FLICE-inhibitory proteins, regulators of death receptor-mediated apoptosis. Mol. Cell. Biol. 2001, 21, 8247-8254.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 8247-8254
-
-
Krueger, A.1
Baumann, S.2
Krammer, P.H.3
Kirchhoff, S.4
-
67
-
-
0033791307
-
Apoptosis signaling
-
Strasser, A.; O'Connor, L.; Dixit, V.M. Apoptosis signaling. Annu. Rev. Biochem. 2000, 69, 217-245.
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 217-245
-
-
Strasser, A.1
O'Connor, L.2
Dixit, V.M.3
-
68
-
-
0035797881
-
Apoptotic cell removal
-
Henson, P.M.; Bratton, D.L.; Fadok, V.A. Apoptotic cell removal. Curr. Biol. 2001, 11, 795-805.
-
(2001)
Curr. Biol
, vol.11
, pp. 795-805
-
-
Henson, P.M.1
Bratton, D.L.2
Fadok, V.A.3
-
69
-
-
0036463405
-
A matter of life and death
-
Green, D.R.; Evan, G.I. A matter of life and death. Cancer Cell 2002, 1, 19-30.
-
(2002)
Cancer Cell
, vol.1
, pp. 19-30
-
-
Green, D.R.1
Evan, G.I.2
-
70
-
-
0032575750
-
Caspases, enemies within
-
Thornberry, N.A.; Lazebnik, Y. Caspases, enemies within. Science 1998, 281, 1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
71
-
-
0032559799
-
The caspase-3 precursor has a cytosolic and mitochondrial distribution, implications for apoptotic signaling
-
Mancini, M.; Nicholson, D.W.; Roy, S.; Thornberry, N.A.; Peterson, E.P.; Casciola-Rosen, L.A.; Rosen, A. The caspase-3 precursor has a cytosolic and mitochondrial distribution, implications for apoptotic signaling. J. Cell Biol. 1998, 140, 1485-1495.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 1485-1495
-
-
Mancini, M.1
Nicholson, D.W.2
Roy, S.3
Thornberry, N.A.4
Peterson, E.P.5
Casciola-Rosen, L.A.6
Rosen, A.7
-
72
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M.O. The biochemistry of apoptosis. Nature 2000, 407, 770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
73
-
-
0030931876
-
Caspases, the executioners of apoptosis
-
Cohen, G.M. Caspases, the executioners of apoptosis. Biochem. J. 1997, 336, 1-16.
-
(1997)
Biochem. J.
, vol.336
, pp. 1-16
-
-
Cohen, G.M.1
-
74
-
-
26044483530
-
Apoptosis, a basic physiologic process in wound healing
-
Rai, N.K.; Tripathi, K.; Sharma, D.; Shukla, V.K. Apoptosis, a basic physiologic process in wound healing. Int. J. Low Extrem. Wounds 2005, 4, 138-144.
-
(2005)
Int. J. Low Extrem. Wounds
, vol.4
, pp. 138-144
-
-
Rai, N.K.1
Tripathi, K.2
Sharma, D.3
Shukla, V.K.4
-
75
-
-
0032491577
-
Caspase-14 is a novel developmentally regulated protease
-
Hu, S.; Snipas, S.J.; Vincenz, C.; Salvesen, G.; Dixit, V.M. Caspase-14 is a novel developmentally regulated protease. J. Biol. Chem. 1998, 273, 29648-29653.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29648-29653
-
-
Hu, S.1
Snipas, S.J.2
Vincenz, C.3
Salvesen, G.4
Dixit, V.M.5
-
76
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
Nakagawa, T.; Zhu, H.; Morishima, N.; Li, E.; Xu, J.; Yankner, B.A.; Yuan, J. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000, 403, 98-103.
-
(2000)
Nature
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
77
-
-
0034801418
-
Evidence that caspase-13 is not a human but a bovine gene
-
Koenig, U.; Eckhart, L.; Tschachler, E. Evidence that caspase-13 is not a human but a bovine gene. Biochem. Biophys. Res. Commun. 2001, 285, 1150-1154.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.285
, pp. 1150-1154
-
-
Koenig, U.1
Eckhart, L.2
Tschachler, E.3
-
78
-
-
0036792478
-
Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response
-
Kang, S.J.; Wang, S.; Kuida, K.; Yuan, J. Distinct downstream pathways of caspase-11 in regulating apoptosis and cytokine maturation during septic shock response. Cell Death Differ. 2002, 9, 1115-1125.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 1115-1125
-
-
Kang, S.J.1
Wang, S.2
Kuida, K.3
Yuan, J.4
-
79
-
-
0029884873
-
Expression and activation of tissue transglutaminase in apoptotic cells of involuting rodent mammary tissue
-
Nemes, Z., Jr.; Friis, R.R.; Aeschlimann, D.; Saurer, S.; Paulsson, M.; Fésüs, L. Expression and activation of tissue transglutaminase in apoptotic cells of involuting rodent mammary tissue. Eur. J. Cell Biol. 1996, 70, 125-133.
-
(1996)
Eur. J. Cell Biol.
, vol.70
, pp. 125-133
-
-
Nemes Jr., Z.1
Friis, R.R.2
Aeschlimann, D.3
Saurer, S.4
Paulsson, M.5
Fésüs, L.6
-
80
-
-
0028867995
-
The role of DNA fragmentation in apoptosis
-
Bortner, C.D.; Oldenburg, N.B.; Cidlowski, J.A. The role of DNA fragmentation in apoptosis. Trends Cell Biol. 1995, 5, 21-26.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 21-26
-
-
Bortner, C.D.1
Oldenburg, N.B.2
Cidlowski, J.A.3
-
81
-
-
0030697996
-
Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase
-
Bratton, D.L.; Fadok, V.A.; Richter, D.A.; Kailey, J.M.; Guthrie, L.A.; Henson, P.M. Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase. J. Biol. Chem. 1997, 272, 26159-26165.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26159-26165
-
-
Bratton, D.L.1
Fadok, V.A.2
Richter, D.A.3
Kailey, J.M.4
Guthrie, L.A.5
Henson, P.M.6
-
82
-
-
0037390598
-
Annexin I is an endogenous ligand that mediates apoptotic cell engulfment
-
Arur, S.; Uche, U.E.; Rezaul, K.; Fong, M.; Scranton, V.; Cowan, A.E.; Mohler, W.; Han, D.K. Annexin I is an endogenous ligand that mediates apoptotic cell engulfment. Dev. Cell 2003, 4, 587-598.
-
(2003)
Dev. Cell
, vol.4
, pp. 587-598
-
-
Arur, S.1
Uche, U.E.2
Rezaul, K.3
Fong, M.4
Scranton, V.5
Cowan, A.E.6
Mohler, W.7
Han, D.K.8
-
83
-
-
26844468253
-
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
-
Gardai, S.J.; McPhillips, K.A.; Frasch, S.C.; Janssen, W.J.; Starefeldt, A.; Murphy-Ullrich, J.E.; Bratton, D.L.; Oldenborg, P.-A.; Michalak, M.; Henson, P.M. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell 2005, 123, 321-334.
-
(2005)
Cell
, vol.123
, pp. 321-334
-
-
Gardai, S.J.1
McPhillips, K.A.2
Frasch, S.C.3
Janssen, W.J.4
Starefeldt, A.5
Murphy-Ullrich, J.E.6
Bratton, D.L.7
Oldenborg, P.-A.8
Michalak, M.9
Henson, P.M.10
-
84
-
-
84867267553
-
Cancer chemoprevention through the induction of apoptosis by natural compounds
-
Kuno, T.; Tsukamoto, T.; Hara, A.; Tanaka, T. Cancer chemoprevention through the induction of apoptosis by natural compounds. J. Biophys. Chem. 2012, 3, 156-173.
-
(2012)
J. Biophys. Chem
, vol.3
, pp. 156-173
-
-
Kuno, T.1
Tsukamoto, T.2
Hara, A.3
Tanaka, T.4
-
85
-
-
0031719672
-
Long-term follow-up of axillary node-positive breast cancer patients receiving adjuvant tamoxifen alone, patterns of recurrence
-
Fisher, B.; Perera, F.; Cooke, A.; Opeitum A, Stitt L. Long-term follow-up of axillary node-positive breast cancer patients receiving adjuvant tamoxifen alone, patterns of recurrence. Int. J. Radiat. Oncol. Biol. Phys. 1998, 42, 117-123.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.42
, pp. 117-123
-
-
Fisher, B.1
Perera, F.2
Cooke, A.3
Opeitum, A.4
Stitt, L.5
-
86
-
-
0033575083
-
The effect of raloxifene on risk of breast cancer in postmenopausal women, results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation
-
Cummings, S.; Eckert, S.; Krueger, K.; Grady, D.; Powles, T.J.; Cauley, J.A.; Norton, L.; Nickelsen, T.; Bjarnason, N.H.; Morrow, M.; et al. The effect of raloxifene on risk of breast cancer in postmenopausal women, results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. J. Am. Med. Assoc. 1999, 281, 2189-2197.
-
(1999)
J. Am. Med. Assoc.
, vol.281
, pp. 2189-2197
-
-
Cummings, S.1
Eckert, S.2
Krueger, K.3
Grady, D.4
Powles, T.J.5
Cauley, J.A.6
Norton, L.7
Nickelsen, T.8
Bjarnason, N.H.9
Morrow, M.10
-
87
-
-
0033520713
-
Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer
-
Veronesi, U.; de Palo, G.; Marubini, E.; Costa, A.; Formelli, F.; Mariani, L.; Decensi, A.; Camerini, T.; del Turco, M.R.; di Mauro, M.G.; et al. Randomized trial of fenretinide to prevent second breast malignancy in women with early breast cancer. J. Natl. Cancer Inst. 1999, 91, 1847-1856.
-
(1999)
J. Natl. Cancer Inst
, vol.91
, pp. 1847-1856
-
-
Veronesi, U.1
de Palo, G.2
Marubini, E.3
Costa, A.4
Formelli, F.5
Mariani, L.6
Decensi, A.7
Camerini, T.8
del Turco, M.R.9
di Mauro, M.G.10
-
88
-
-
44649111827
-
Cancer chemoprevention: A radical perspective
-
Hail, N., Jr.; Cortes, M.; Drake, E.N.; Spallholz, J.E. Cancer chemoprevention: A radical perspective. Free Rad. Biol. Med. 2008, 45, 97-110.
-
(2008)
Free Rad. Biol. Med
, vol.45
, pp. 97-110
-
-
Hail Jr., N.1
Cortes, M.2
Drake, E.N.3
Spallholz, J.E.4
-
89
-
-
0033233393
-
Cancer chemoprevention: Progress and promise
-
Kelloff, G.J.; Sigman, C.C.; Greenwald, P. Cancer chemoprevention: Progress and promise. Eur. J. Cancer 1999, 35, 2031-2038.
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 2031-2038
-
-
Kelloff, G.J.1
Sigman, C.C.2
Greenwald, P.3
-
90
-
-
0642341485
-
Chemoprevention of cancer-Focusing on clinical trials
-
Kakizoe, T. Chemoprevention of cancer-Focusing on clinical trials. Jpn. J. Clin. Oncol. 2003, 33, 421-442.
-
(2003)
Jpn. J. Clin. Oncol
, vol.33
, pp. 421-442
-
-
Kakizoe, T.1
-
91
-
-
0036955121
-
Botanicals in cancer chemoprevention
-
Park, E.J.; Pezzuto, J.M. Botanicals in cancer chemoprevention. Cancer Metast. Rev. 2002, 21, 231-255.
-
(2002)
Cancer Metast. Rev
, vol.21
, pp. 231-255
-
-
Park, E.J.1
Pezzuto, J.M.2
-
92
-
-
44849135016
-
Bioactive food components and cancer risk reduction
-
Stan, S.D.; Kar, S.; Stoner, G.D.; Singh, S.V. Bioactive food components and cancer risk reduction. J. Cell. Biochem. 2008, 104, 339-356.
-
(2008)
J. Cell. Biochem
, vol.104
, pp. 339-356
-
-
Stan, S.D.1
Kar, S.2
Stoner, G.D.3
Singh, S.V.4
-
93
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
Newman, D.J.; Cragg, G.M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 2007, 70, 461-477.
-
(2007)
J. Nat. Prod.
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
94
-
-
79251496420
-
Marine natural products
-
Blunt, J.W.; Copp, B.R.; Munro, M.H.G.; Northcote, P.T.; Prinsep, M.R. Marine natural products. Nat. Prod. Rep. 2011, 28, 196-268.
-
(2011)
Nat. Prod. Rep
, vol.28
, pp. 196-268
-
-
Blunt, J.W.1
Copp, B.R.2
Munro, M.H.G.3
Northcote, P.T.4
Prinsep, M.R.5
-
95
-
-
77957374075
-
Microtubule-binding agents: A dynamic field of cancer therapeutics
-
Dumontet, C.; Jordan, M.A. Microtubule-binding agents: A dynamic field of cancer therapeutics. Nat. Rev. Drug. Discov. 2010, 17, 790-803.
-
(2010)
Nat. Rev. Drug. Discov.
, vol.17
, pp. 790-803
-
-
Dumontet, C.1
Jordan, M.A.2
-
96
-
-
77956016499
-
Cancer prevention with natural compounds
-
Gullett, N.P.; Ruhul Amin, A.R.; Bayraktar, S.; Pezzuto, J.M.; Shin, D.M.; Khuri, F.R.; Aggarwal, B.B.; Surh, Y.J.; Kucuk, O. Cancer prevention with natural compounds. Semin. Oncol. 2010, 37, 258-281.
-
(2010)
Semin. Oncol
, vol.37
, pp. 258-281
-
-
Gullett, N.P.1
Ruhul Amin, A.R.2
Bayraktar, S.3
Pezzuto, J.M.4
Shin, D.M.5
Khuri, F.R.6
Aggarwal, B.B.7
Surh, Y.J.8
Kucuk, O.9
-
97
-
-
62149106334
-
Antitumour polyether macrolides, four new halichondrins from the New Zealand deep-water marine sponge Lissodendoryx sp
-
Hickford, S.J.; Blunt, J.W.; Munro, M.H. Antitumour polyether macrolides, four new halichondrins from the New Zealand deep-water marine sponge Lissodendoryx sp. Bioorg. Med. Chem. 2009, 17, 2199-2203.
-
(2009)
Bioorg. Med. Chem
, vol.17
, pp. 2199-2203
-
-
Hickford, S.J.1
Blunt, J.W.2
Munro, M.H.3
-
98
-
-
3242740479
-
Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp
-
Aoki, S.; Cao, L.; Matsui, K.; Rachmat, R.; Akiyamac, S.; Kobayashia, M. Kendarimide A, a novel peptide reversing P-glycoprotein-mediated multidrug resistance in tumor cells, from a marine sponge of Haliclona sp. Tetrahedron 2004, 60, 7053-7059.
-
(2004)
Tetrahedron
, vol.60
, pp. 7053-7059
-
-
Aoki, S.1
Cao, L.2
Matsui, K.3
Rachmat, R.4
Akiyamac, S.5
Kobayashia, M.6
-
99
-
-
77952574831
-
Marine Drugs from Sponge-Microbe Association-A Review
-
Thomas, T.R.A.; Kavlekar, D.P.; LokaBharathi, P.A. Marine Drugs from Sponge-Microbe Association-A Review. Mar. Drugs 2010, 8, 1417-1468.
-
(2010)
Mar. Drugs
, vol.8
, pp. 1417-1468
-
-
Thomas, T.R.A.1
Kavlekar, D.P.2
LokaBharathi, P.A.3
-
100
-
-
12044259663
-
Marine antitumor agents, 14-deoxycrassin and pseudoplexaurol, new cembranoid diterpenes from the Caribbean gorgonian Pseudoplexaura porosa
-
Rodriguez, A.D.; Martinez, N. Marine antitumor agents, 14-deoxycrassin and pseudoplexaurol, new cembranoid diterpenes from the Caribbean gorgonian Pseudoplexaura porosa. Experientia 1993, 49, 179-181.
-
(1993)
Experientia
, vol.49
, pp. 179-181
-
-
Rodriguez, A.D.1
Martinez, N.2
-
101
-
-
73449131956
-
Antitumor Compounds from Marine Actinomycetes
-
Olano, C.; Méndez, C.; Salas, J.A. Antitumor Compounds from Marine Actinomycetes. Mar. Drugs 2009, 7, 210-248.
-
(2009)
Mar. Drugs
, vol.7
, pp. 210-248
-
-
Olano, C.1
Méndez, C.2
Salas, J.A.3
-
102
-
-
77952974176
-
Pachycladins A-E, prostate cancer invasion and migration inhibitory Eunicellin-based diterpenoids from the red sea soft coral Cladiella pachyclados
-
Hassan, H.M.; Khanfar, M.A.; Elnagar, A.Y.; Mohammed, R.; Shaala, L.A.; Youssef, D.T.A.; Hifnawy, M.S.; Sayed, K.A.E. Pachycladins A-E, prostate cancer invasion and migration inhibitory Eunicellin-based diterpenoids from the red sea soft coral Cladiella pachyclados. J. Nat. Prod. 2010, 73, 848-853.
-
(2010)
J. Nat. Prod.
, vol.73
, pp. 848-853
-
-
Hassan, H.M.1
Khanfar, M.A.2
Elnagar, A.Y.3
Mohammed, R.4
Shaala, L.A.5
Youssef, D.T.A.6
Hifnawy, M.S.7
Sayed, K.A.E.8
-
103
-
-
77954520406
-
NFkappa B: A promising target for natural products in cancer chemoprevention
-
Luqman, S.; Pezzuto, J.M. NFkappa B: A promising target for natural products in cancer chemoprevention. Phytother. Res. 2010, 24, 949-963.
-
(2010)
Phytother. Res.
, vol.24
, pp. 949-963
-
-
Luqman, S.1
Pezzuto, J.M.2
-
104
-
-
33745298519
-
Nuclear factor-kappa B in cancer development and progression
-
Karin, M. Nuclear factor-kappa B in cancer development and progression. Nature 2006, 441, 431-436.
-
(2006)
Nature
, vol.441
, pp. 431-436
-
-
Karin, M.1
-
105
-
-
34548079500
-
Targeting the AKT protein kinase for cancer chemoprevention
-
Crowell, J.A.; Steele, V.E.; Fay, J.R. Targeting the AKT protein kinase for cancer chemoprevention. Mol. Cancer Therap. 2007, 6, 2139-2148.
-
(2007)
Mol. Cancer Therap
, vol.6
, pp. 2139-2148
-
-
Crowell, J.A.1
Steele, V.E.2
Fay, J.R.3
-
106
-
-
77955648969
-
Pathway-based identification of biomarkers for targeted therapeutics, Personalized oncology with PI3K pathway inhibitors
-
Andersen, J.N.; Sathyanarayanan, S.; di Bacco, A.; Chi, A.; Zhang, T.; Chen, A.H.; Dolinski, B.; Kraus, M.; Roberts, B.; Arthur, W.; et al. Pathway-based identification of biomarkers for targeted therapeutics, Personalized oncology with PI3K pathway inhibitors. Sci. Transl. Med. 2010, 2, 43-55.
-
(2010)
Sci. Transl. Med
, vol.2
, pp. 43-55
-
-
Andersen, J.N.1
Sathyanarayanan, S.2
di Bacco, A.3
Chi, A.4
Zhang, T.5
Chen, A.H.6
Dolinski, B.7
Kraus, M.8
Roberts, B.9
Arthur, W.10
-
107
-
-
65249171974
-
Arenamides A-C, cytotoxic NF kappa B inhibitors from the marine actinomycetes Salinispora arenicola
-
Asolkar, R.N.; Freel, K.C.; Jensen, P.R.; Fenical, W.; Kondratyuk, T.P.; Park, E.J.; Pezzuto, J.M. Arenamides A-C, cytotoxic NF kappa B inhibitors from the marine actinomycetes Salinispora arenicola. J. Nat. Prod. 2009, 72, 396-402.
-
(2009)
J. Nat. Prod.
, vol.72
, pp. 396-402
-
-
Asolkar, R.N.1
Freel, K.C.2
Jensen, P.R.3
Fenical, W.4
Kondratyuk, T.P.5
Park, E.J.6
Pezzuto, J.M.7
-
108
-
-
71349086366
-
Heteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death
-
Schumacher, M.; Cerella, C.; Eifes, S.; Chateauvieux, S.; Morceau, F.; Jaspars, M.; Dicato, M.; Diederich, M. Heteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death. Biochem. Pharmacol. 2010, 79, 610-622.
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 610-622
-
-
Schumacher, M.1
Cerella, C.2
Eifes, S.3
Chateauvieux, S.4
Morceau, F.5
Jaspars, M.6
Dicato, M.7
Diederich, M.8
-
109
-
-
84856296572
-
Marine Compounds Selectively Induce Apoptosis in Female Reproductive Cancer Cells but Not in Primary-Derived Human Reproductive Granulosa Cells
-
Edwards, V.; Benkendorff, K.; Young, F. Marine Compounds Selectively Induce Apoptosis in Female Reproductive Cancer Cells but Not in Primary-Derived Human Reproductive Granulosa Cells. Mar. Drugs 2012, 10, 64-83.
-
(2012)
Mar. Drugs
, vol.10
, pp. 64-83
-
-
Edwards, V.1
Benkendorff, K.2
Young, F.3
-
110
-
-
77953015002
-
Cryptosphaerolide, a cytotoxic Mcl-1 inhibitor from a marine-derived ascomycete related to the genus Cryptosphaeria
-
Oh, H.; Jensen, P.R.; Murphy, B.T.; Fiorilla, C.; Sullivan, J.F.; Ramsey, T.; Fenical, W. Cryptosphaerolide, a cytotoxic Mcl-1 inhibitor from a marine-derived ascomycete related to the genus Cryptosphaeria. J. Nat. Prod. 2010, 73, 998-1001.
-
(2010)
J. Nat. Prod.
, vol.73
, pp. 998-1001
-
-
Oh, H.1
Jensen, P.R.2
Murphy, B.T.3
Fiorilla, C.4
Sullivan, J.F.5
Ramsey, T.6
Fenical, W.7
-
111
-
-
27844519630
-
Topoisomerase Inhibitors of Marine Origin and Their Potential Use as Anticancer Agents
-
Dias, N.; Vezin, H.; Lansiaux, A.; Bailly, C. Topoisomerase Inhibitors of Marine Origin and Their Potential Use as Anticancer Agents. Top. Curr. Chem. 2005, 253, 89-108.
-
(2005)
Top. Curr. Chem.
, vol.253
, pp. 89-108
-
-
Dias, N.1
Vezin, H.2
Lansiaux, A.3
Bailly, C.4
-
112
-
-
0029039532
-
Binding to DNA and cytotoxic evaluation of ascididemin, the major alkaloid from the Mediterranean ascidian
-
Bonnard, I.; Bontemps, N.; Lahmy, S.; Banaigs, B.; Combaut, G.; Francisco, C.; Colson, P.; Houssier, C.; Waring, M.J.; Bailly, C. Binding to DNA and cytotoxic evaluation of ascididemin, the major alkaloid from the Mediterranean ascidian Cystodytes dellechiajei. Anticancer Drug Des. 1995, 10, 333-346.
-
(1995)
Cystodytes dellechiajei. Anticancer Drug Des.
, vol.10
, pp. 333-346
-
-
Bonnard, I.1
Bontemps, N.2
Lahmy, S.3
Banaigs, B.4
Combaut, G.5
Francisco, C.6
Colson, P.7
Houssier, C.8
Waring, M.J.9
Bailly, C.10
-
113
-
-
0034664192
-
Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells
-
Dassonneville, L.; Wattez, N.; Baldeyrou, B.; Mahieu, C.; Lansiaux, A.; Banaigs, B.; Bonnard, I.; Bailly, C. Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells. Biochem. Pharmacol. 2000, 60, 527-537.
-
(2000)
Biochem. Pharmacol.
, vol.60
, pp. 527-537
-
-
Dassonneville, L.1
Wattez, N.2
Baldeyrou, B.3
Mahieu, C.4
Lansiaux, A.5
Banaigs, B.6
Bonnard, I.7
Bailly, C.8
-
114
-
-
12144288129
-
Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D, triester derivatives incorporating amino acid residues
-
Tardy, C.; Facompré, M.; Laine, W.; Baldeyroua, B.; arca-Gravalosb, D.; Franceschb, A.; Mateob, C.; Pastorb, A.; Jiménezb, J.A.; Manzanares, I.; et al. Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D, triester derivatives incorporating amino acid residues. Bioorg. Med. Chem. 2004, 12, 1697-1712.
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 1697-1712
-
-
Tardy, C.1
Facompré, M.2
Laine, W.3
Baldeyroua, B.4
Arca-Gravalosb, D.5
Franceschb, A.6
Mateob, C.7
Pastorb, A.8
Jiménezb, J.A.9
Manzanares, I.10
-
115
-
-
73149093206
-
Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D
-
Ballot, C.; Kluza, J.; Martoriati, A.; Nyman, U.; Formstecher, P.; Joseph, B.; Bailly, C.; Marchetti, P. Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D. Mol. Cancer Ther. 2009, 8, 3307-3317.
-
(2009)
Mol. Cancer Ther
, vol.8
, pp. 3307-3317
-
-
Ballot, C.1
Kluza, J.2
Martoriati, A.3
Nyman, U.4
Formstecher, P.5
Joseph, B.6
Bailly, C.7
Marchetti, P.8
-
116
-
-
51649114209
-
Spongistatin 1: A new chemosensitizingmarine compoundthat degrades XIAP
-
Schyschka, L.; Rudy, A.; Jeremias, I.; Barth, N.; Pettit, G.R.; Vollmar, A.M. Spongistatin 1: A new chemosensitizingmarine compoundthat degrades XIAP. Leukemia 2008, 22, 1737-1745.
-
(2008)
Leukemia
, vol.22
, pp. 1737-1745
-
-
Schyschka, L.1
Rudy, A.2
Jeremias, I.3
Barth, N.4
Pettit, G.R.5
Vollmar, A.M.6
-
117
-
-
34548510609
-
Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110
-
Shin, H.J.; Jeong, H.S.; Lee, H.S.; Park, S.K.; Hwan, M.K.; Ho, J.K. Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110. J. Microbiol. Biotech. 2007, 17, 1403-1406.
-
(2007)
J. Microbiol. Biotech.
, vol.17
, pp. 1403-1406
-
-
Shin, H.J.1
Jeong, H.S.2
Lee, H.S.3
Park, S.K.4
Hwan, M.K.5
Ho, J.K.6
-
118
-
-
38449087673
-
Streptochlorin, a marine natural product, inhibits NF-. B activation and suppresses angiogenesis in vitro
-
Choi, I.K.; Shin, H.J.; Lee, H.S.; Kwon, H.J. Streptochlorin, a marine natural product, inhibits NF-. B activation and suppresses angiogenesis in vitro. J. Microbiol. Biotech. 2007, 17, 1338-1343.
-
(2007)
J. Microbiol. Biotech.
, vol.17
, pp. 1338-1343
-
-
Choi, I.K.1
Shin, H.J.2
Lee, H.S.3
Kwon, H.J.4
-
119
-
-
49149119431
-
Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells
-
Park, C.; Shin, H.J.; Kim, G.Y.; Kwon, T.K.; Nam, T.J.; Kim, S.K.; Cheong, J.; Choi, I.W.; Choi, Y.H. Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells. Toxicol. In Vitro 2008, 22, 1573-1581.
-
(2008)
Toxicol. In Vitro
, vol.22
, pp. 1573-1581
-
-
Park, C.1
Shin, H.J.2
Kim, G.Y.3
Kwon, T.K.4
Nam, T.J.5
Kim, S.K.6
Cheong, J.7
Choi, I.W.8
Choi, Y.H.9
-
120
-
-
0033839792
-
Metabolites of marine algae collected from Karachi-coasts of Arabian sea
-
Ali, M.S.; Jahangir, M.; Saleem, M.; Pervez, M.K.; Hameed, S.; Ahmad, V.U. Metabolites of marine algae collected from Karachi-coasts of Arabian sea. Nat. Prod. Sci. 2000, 6, 61-65.
-
(2000)
Nat. Prod. Sci.
, vol.6
, pp. 61-65
-
-
Ali, M.S.1
Jahangir, M.2
Saleem, M.3
Pervez, M.K.4
Hameed, S.5
Ahmad, V.U.6
-
121
-
-
0031128207
-
Antioxidant properties of phenolic compounds
-
Rice-Evans, C.A.; Miller, N.J.; Paganga, G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 1997, 2, 152-159.
-
(1997)
Trends Plant Sci.
, vol.2
, pp. 152-159
-
-
Rice-Evans, C.A.1
Miller, N.J.2
Paganga, G.3
-
122
-
-
0000411192
-
Critical light conditions for young Ecklonia cava and Eisenia bicyclis with reference to photosynthesis
-
Maegawa, M.; Yokohama, Y.; Aruga, Y. Critical light conditions for young Ecklonia cava and Eisenia bicyclis with reference to photosynthesis. Hydrobiologia 1987, 151, 447-455.
-
(1987)
Hydrobiologia
, vol.151
, pp. 447-455
-
-
Maegawa, M.1
Yokohama, Y.2
Aruga, Y.3
-
123
-
-
67349194659
-
Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells
-
Kong, S.C.; Kim, A.J.; Yoon, Y.N.; Kim, S.K. Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells. Food Chem. Toxicol. 2009, 47, 1653-1658.
-
(2009)
Food Chem. Toxicol.
, vol.47
, pp. 1653-1658
-
-
Kong, S.C.1
Kim, A.J.2
Yoon, Y.N.3
Kim, S.K.4
-
124
-
-
0037147636
-
Enzymic preparation of water-soluble chitosan and their antitumor activity
-
Qin, C.; Du, Y.; Xiao, L.; Li, Z.; Gao, X. Enzymic preparation of water-soluble chitosan and their antitumor activity. Int. J. Biol. Macromol. 2002, 31, 111-117.
-
(2002)
Int. J. Biol. Macromol.
, vol.31
, pp. 111-117
-
-
Qin, C.1
Du, Y.2
Xiao, L.3
Li, Z.4
Gao, X.5
-
125
-
-
78951478373
-
Diethylaminoethyl chitosan induces apoptosis in HeLa cells via activation of caspase-3 and p53 expression
-
Lee, H.S.; Ryua, B.; Je, Y.J.; Kim, S.K. Diethylaminoethyl chitosan induces apoptosis in HeLa cells via activation of caspase-3 and p53 expression. Carbohydr. Polym. 2011, 84, 571-578.
-
(2011)
Carbohydr. Polym.
, vol.84
, pp. 571-578
-
-
Lee, H.S.1
Ryua, B.2
Je, Y.J.3
Kim, S.K.4
-
126
-
-
70349319640
-
Fucoidan Induces Apoptosis through Activation of Caspase-8 on Human Breast Cancer MCF-7 Cells
-
Yamasaki-Miyamoto, Y.; Yamasaki, M.; Tachibana, H.; Yamada, K. Fucoidan Induces Apoptosis through Activation of Caspase-8 on Human Breast Cancer MCF-7 Cells. J. Agric. Food Chem. 2009, 57, 8677-8682.
-
(2009)
J. Agric. Food Chem.
, vol.57
, pp. 8677-8682
-
-
Yamasaki-Miyamoto, Y.1
Yamasaki, M.2
Tachibana, H.3
Yamada, K.4
|