Essential role of mitochondria in apoptosis of cancer cells induced by the marine alkaloid Lamellarin D

Molecular Cancer Therapeutics

Volumn 8, Issue 12, 2009, Pages 3307-3317

  Ballot, Caroline ^a   Kluza, Jérome ^a   Martoriati, Alain ^a   Nyman, Ulrika ^b   Formstecher, Pierre ^a   Joseph, Bertrand ^b   Bailly, Christian ^a,d   Marchetti, Philippe ^a,c  

^a JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^b KAROLINSKA INSTITUTE   (Sweden)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOTOXIC AGENT; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; FAS ANTIGEN; FAS LIGAND; HISTONE H2AX; LAMELLARIN D; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; RAD51 PROTEIN; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL DEATH; CELL NUCLEUS; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRION; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; COUMARINS; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; FLOW CYTOMETRY; HCT116 CELLS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; HISTONES; HUMANS; IMMUNOBLOTTING; INHIBITOR OF APOPTOSIS PROTEINS; ISOQUINOLINES; JURKAT CELLS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MUTATION; NEOPLASMS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 73149093206     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-09-0639     Document Type: Article

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