Oncogenic AKTivation of translation as a therapeutic target

British Journal of Cancer

Volumn 105, Issue 3, 2011, Pages 329-336

  Hsieh, A C ^a,b   Truitt, M L ^a   Ruggero, D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 EGI 1; AGENTS AFFECTING PROTEIN METABOLISM; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; EVEROLIMUS; INITIATION FACTOR 4E; INITIATION FACTOR 4G; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PP 242; PROTEIN KINASE B; RAPAMYCIN; RIBAVIRIN; TEMSIROLIMUS; TORIN 1; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; BIOGENESIS; CARCINOGENESIS; CELL TRANSFORMATION; DRUG DOSE ESCALATION; DRUG MECHANISM; DRUG TARGETING; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REVIEW; RIBOSOME; RNA TRANSLATION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; TRANSLATION INITIATION; TRANSLATION REGULATION;

CELL TRANSFORMATION, NEOPLASTIC; HUMANS; PEPTIDE CHAIN ELONGATION, TRANSLATIONAL; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMES; TRANSCRIPTIONAL ACTIVATION;

EID: 79960839035     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2011.241     Document Type: Review

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