-
1
-
-
15744381238
-
The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro
-
Bregenholt S, Moldrup A, Blume N, Karlsen AE, Nissen Friedrichsen B, Tornhave D, Knudsen LB & Petersen JS 2005 The long-acting glucagon-like peptide-1 analogue, liraglutide, inhibits beta-cell apoptosis in vitro. Biochemical and Biophysical Research Communications 330 577-584.
-
(2005)
Biochemical and Biophysical Research Communications
, vol.330
, pp. 577-584
-
-
Bregenholt, S.1
Moldrup, A.2
Blume, N.3
Karlsen, A.E.4
Nissen Friedrichsen, B.5
Tornhave, D.6
Knudsen, L.B.7
Petersen, J.S.8
-
2
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA & Butler PC 2003 Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52 102-110.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
3
-
-
19944432792
-
2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells
-
2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells. Diabetes 54 452-461.
-
(2005)
Diabetes
, vol.54
, pp. 452-461
-
-
Cardozo, A.K.1
Ortis, F.2
Storling, J.3
Feng, Y.M.4
Rasschaert, J.5
Tonnesen, M.6
Van Eylen, F.7
Mandrup-Poulsen, T.8
Herchuelz, A.9
Eizirik, D.L.10
-
4
-
-
3042823921
-
Insulin-independent effects of GLP-1 on canine liver glucose metabolism: Duration of infusion and involvement of hepatoportal region
-
Dardevet D, Moore MC, Neal D, DiCostanzo CA, Snead W & Cherrington AD 2004 Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of infusion and involvement of hepatoportal region. American Journal of Physiology, Endocrinology and Metabolism 287 E75-E81.
-
(2004)
American Journal of Physiology, Endocrinology and Metabolism
, vol.287
-
-
Dardevet, D.1
Moore, M.C.2
Neal, D.3
DiCostanzo, C.A.4
Snead, W.5
Cherrington, A.D.6
-
5
-
-
0033034807
-
Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
-
Donath MY, Gross DJ, Cerasi E & Kaiser N 1999 Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48 738-744.
-
(1999)
Diabetes
, vol.48
, pp. 738-744
-
-
Donath, M.Y.1
Gross, D.J.2
Cerasi, E.3
Kaiser, N.4
-
6
-
-
0037312818
-
Glucagon-like peptides: Regulators of cell proliferation, differentiation, and apoptosis
-
Drucker DJ 2003 Glucagon-like peptides: regulators of cell proliferation, differentiation, and apoptosis. Molecular Endocrinology 17 161-171.
-
(2003)
Molecular Endocrinology
, vol.17
, pp. 161-171
-
-
Drucker, D.J.1
-
8
-
-
0028077525
-
Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: One of several potential extrapancreatic sites of GLP-1 action
-
Egan JM, Montrose-Rafizadeh C, Wang Y, Bernier M & Roth J 1994 Glucagon-like peptide-1(7-36) amide (GLP-1) enhances insulin-stimulated glucose metabolism in 3T3-L1 adipocytes: one of several potential extrapancreatic sites of GLP-1 action. Endocrinology 135 2070-2075.
-
(1994)
Endocrinology
, vol.135
, pp. 2070-2075
-
-
Egan, J.M.1
Montrose-Rafizadeh, C.2
Wang, Y.3
Bernier, M.4
Roth, J.5
-
9
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh L, Singh G & Raufman JP 1992 Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. Journal of Biological Chemistry 267 7402-7405.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
Singh, G.4
Raufman, J.P.5
-
10
-
-
0024459130
-
Calmodulin-induced early-onset diabetes in transgenic mice
-
Epstein PN, Overbeek PA & Means AR 1989 Calmodulin-induced early-onset diabetes in transgenic mice. Cell 58 1067-1073.
-
(1989)
Cell
, vol.58
, pp. 1067-1073
-
-
Epstein, P.N.1
Overbeek, P.A.2
Means, A.R.3
-
11
-
-
15444380712
-
Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight
-
Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, Baron AD, Parkes DG & Young AA 2005 Exenatide (exendin-4) improves insulin sensitivity and β-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight. Endocrinology 146 2069-2076.
-
(2005)
Endocrinology
, vol.146
, pp. 2069-2076
-
-
Gedulin, B.R.1
Nikoulina, S.E.2
Smith, P.A.3
Gedulin, G.4
Nielsen, L.L.5
Baron, A.D.6
Parkes, D.G.7
Young, A.A.8
-
12
-
-
0030846483
-
Multisite regulation of insulin secretion by cAMP-increasing agonists: Evidence that glucagon-hke peptide 1 and glucagon act via distinct receptors
-
Gromada J, Ding WG, Barg S, Renstrom E & Rorsman P 1997 Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-hke peptide 1 and glucagon act via distinct receptors. Pflugers Archiv 434 515-524.
-
(1997)
Pflugers Archiv
, vol.434
, pp. 515-524
-
-
Gromada, J.1
Ding, W.G.2
Barg, S.3
Renstrom, E.4
Rorsman, P.5
-
13
-
-
0036895383
-
Endoplasmic reticulum stress and the development of diabetes: A review
-
Harding HP & Ron D 2002 Endoplasmic reticulum stress and the development of diabetes: a review. Diabetes 51 (Suppl 3) S455-S461.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL. 3
-
-
Harding, H.P.1
Ron, D.2
-
14
-
-
34247387534
-
Mechanisms of pancreatic β-cell destruction: Immune and nonimmune
-
Eds D Hanahan, HO McDevitt & GF Cahill. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory
-
Harrison LC, Campbell IL, Allison J & Miller JF 1989 Mechanisms of pancreatic β-cell destruction: immune and nonimmune. In Perspectives on the Molecular Biology and Immunology of the Pancreatic β Cell, pp 93-102. Eds D Hanahan, HO McDevitt & GF Cahill. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory.
-
(1989)
Perspectives on the Molecular Biology and Immunology of the Pancreatic β Cell
, pp. 93-102
-
-
Harrison, L.C.1
Campbell, I.L.2
Allison, J.3
Miller, J.F.4
-
15
-
-
0038339191
-
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2
-
Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M & Montminy M 2003 cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2. Genes and Development 17 1575-1580.
-
(2003)
Genes and Development
, vol.17
, pp. 1575-1580
-
-
Jhala, U.S.1
Canettieri, G.2
Screaton, R.A.3
Kulkarni, R.N.4
Krajewski, S.5
Reed, J.6
Walker, J.7
Lin, X.8
White, M.9
Montminy, M.10
-
16
-
-
0037232658
-
2+ release in INS-1 pancreatic beta cells
-
2+ release in INS-1 pancreatic beta cells. Journal of Physiology 546 175-189.
-
(2003)
Journal of Physiology
, vol.546
, pp. 175-189
-
-
Kang, G.1
Holz, G.G.2
-
17
-
-
2542535432
-
2+-ATPase (SERCA)-2b and -3
-
2+-ATPase (SERCA)-2b and -3. Diabetes 53 1517-1525.
-
(2004)
Diabetes
, vol.53
, pp. 1517-1525
-
-
Kulkarni, R.N.1
Roper, M.G.2
Dahlgren, G.3
Shih, D.Q.4
Kauri, L.M.5
Peters, J.L.6
Stoffel, M.7
Kennedy, R.T.8
-
19
-
-
0036305993
-
Glucagon-like peptide-1 (GLP-1) and glucose metabolism in human myocytes
-
Luque MA, Gonzalez N, Marquez L, Acitores A, Redondo A, Morales M, Valverde I & Villanueva-Penacarrillo ML 2002 Glucagon-like peptide-1 (GLP-1) and glucose metabolism in human myocytes. Journal of Endocrinology 173 465-473.
-
(2002)
Journal of Endocrinology
, vol.173
, pp. 465-473
-
-
Luque, M.A.1
Gonzalez, N.2
Marquez, L.3
Acitores, A.4
Redondo, A.5
Morales, M.6
Valverde, I.7
Villanueva-Penacarrillo, M.L.8
-
20
-
-
0442305381
-
Apoptotic signal transduction pathways in diabetes
-
Mandrup-Poulsen T 2003 Apoptotic signal transduction pathways in diabetes. Biochemical Pharmacology 66 1433-1440.
-
(2003)
Biochemical Pharmacology
, vol.66
, pp. 1433-1440
-
-
Mandrup-Poulsen, T.1
-
21
-
-
0032941026
-
Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells
-
Montrose-Rafizadeh C, Avdonin P, Garant MJ, Rodgers BD, Kole S, Yang H, Levine MA, Schwindinger W & Bernier M 1999 Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells. Endocrinology 140 1132-1140.
-
(1999)
Endocrinology
, vol.140
, pp. 1132-1140
-
-
Montrose-Rafizadeh, C.1
Avdonin, P.2
Garant, M.J.3
Rodgers, B.D.4
Kole, S.5
Yang, H.6
Levine, M.A.7
Schwindinger, W.8
Bernier, M.9
-
22
-
-
0036022403
-
Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells
-
Oyadomari S, Araki E & Mori M 2002 a Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells. Apoptosis 7 335-345.
-
(2002)
Apoptosis
, vol.7
, pp. 335-345
-
-
Oyadomari, S.1
Araki, E.2
Mori, M.3
-
23
-
-
0036175128
-
Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes
-
Oyadomari S, Koizumi A, Takeda K, Gotoh T, Akira S, Araki E & Mori M 2002 b Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes. Journal of Clinical Investigation 109 525-532.
-
(2002)
Journal of Clinical Investigation
, vol.109
, pp. 525-532
-
-
Oyadomari, S.1
Koizumi, A.2
Takeda, K.3
Gotoh, T.4
Akira, S.5
Araki, E.6
Mori, M.7
-
24
-
-
33644850386
-
Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function
-
Park S, Dong X, Fisher TL, Dunn S, Omer AK, Weir G & White MF 2006 Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function. Journal of Biological Chemistry 281 1159-1168.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 1159-1168
-
-
Park, S.1
Dong, X.2
Fisher, T.L.3
Dunn, S.4
Omer, A.K.5
Weir, G.6
White, M.F.7
-
25
-
-
0028229043
-
2+ sequestration in diabetic mouse islets of Langerhans
-
2+ sequestration in diabetic mouse islets of Langerhans. Journal of Biological Chemistry 269 18279-18282.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 18279-18282
-
-
Roe, M.W.1
Philipson, L.H.2
Frangakis, C.J.3
Kuznetsov, A.4
Mertz, R.J.5
Lancaster, M.E.6
Spencer, B.7
Worley III, J.F.8
Dukes, I.D.9
-
26
-
-
22544444513
-
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
-
Scheuner D, Mierde DV, Song B, Flamez D, Creemers JW, Tsukamoto K, Ribick M, Schuit FC & Kaufinan RJ 2005 Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis. Nature Medicine 11 757-764.
-
(2005)
Nature Medicine
, vol.11
, pp. 757-764
-
-
Scheuner, D.1
Mierde, D.V.2
Song, B.3
Flamez, D.4
Creemers, J.W.5
Tsukamoto, K.6
Ribick, M.7
Schuit, F.C.8
Kaufinan, R.J.9
-
27
-
-
17444391664
-
Cyclic AMP alleviates endoplasmic stress and programmed cell death induced by lipopolysaccharides in human endothelial cells
-
Schildberg FA, Schulz S, Dombrowski F & Minor T 2005 Cyclic AMP alleviates endoplasmic stress and programmed cell death induced by lipopolysaccharides in human endothelial cells. Cell and Tissue Research 320 91-98.
-
(2005)
Cell and Tissue Research
, vol.320
, pp. 91-98
-
-
Schildberg, F.A.1
Schulz, S.2
Dombrowski, F.3
Minor, T.4
-
28
-
-
0018311579
-
Presence and possible role of calcium-dependent regulator (calmodulin) in rat islets of Langerhans
-
Sugden MC, Christie MR & Ashcroft SJ 1979 Presence and possible role of calcium-dependent regulator (calmodulin) in rat islets of Langerhans. FEBS Letters 105 95-100.
-
(1979)
FEBS Letters
, vol.105
, pp. 95-100
-
-
Sugden, M.C.1
Christie, M.R.2
Ashcroft, S.J.3
-
29
-
-
0026775150
-
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1
-
Thorens B 1992 Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. PNAS 89 8641-8645.
-
(1992)
PNAS
, vol.89
, pp. 8641-8645
-
-
Thorens, B.1
-
30
-
-
19744365188
-
Systemic administration of pituitary adenylate cyclase-activating polypeptide maintains beta-cell mass and retards onset of hyperglycaemia in beta-cell-specific calmodulin-overexpressing transgenic mice
-
Tsunekawa S, Miura Y, Yamamoto N, Itoh Y, Ariyoshi Y, Senda T, Oiso Y & Niki I 2005 Systemic administration of pituitary adenylate cyclase-activating polypeptide maintains beta-cell mass and retards onset of hyperglycaemia in beta-cell-specific calmodulin-overexpressing transgenic mice. European Journal of Endocrinology 152 805-811.
-
(2005)
European Journal of Endocrinology
, vol.152
, pp. 805-811
-
-
Tsunekawa, S.1
Miura, Y.2
Yamamoto, N.3
Itoh, Y.4
Ariyoshi, Y.5
Senda, T.6
Oiso, Y.7
Niki, I.8
-
31
-
-
0021712464
-
Calmodulin and pancreatic B-cell function
-
Valverde I & Malaisse WJ 1984 Calmodulin and pancreatic B-cell function. Experientia 40 1061-1068.
-
(1984)
Experientia
, vol.40
, pp. 1061-1068
-
-
Valverde, I.1
Malaisse, W.J.2
-
34
-
-
0036381989
-
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
-
Wang Q & Brubaker PL 2002 Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice. Diabetologia 45 1263-1273.
-
(2002)
Diabetologia
, vol.45
, pp. 1263-1273
-
-
Wang, Q.1
Brubaker, P.L.2
-
35
-
-
0031990996
-
2+]i-reducing action of cAMP in rat pancreatic beta-cells: Involvement of thapsigargin-sensitive stores
-
2+]i-reducing action of cAMP in rat pancreatic beta-cells: involvement of thapsigargin-sensitive stores. American Journal of Physiology 274 C513-C521.
-
(1998)
American Journal of Physiology
, vol.274
-
-
Yaekura, K.1
Yada, T.2
-
37
-
-
0036715261
-
2+-dependent apoptosis of pancreatic beta cells, which can be prevented by inhibition of nitric oxide synthase
-
2+-dependent apoptosis of pancreatic beta cells, which can be prevented by inhibition of nitric oxide synthase. Laboratory Investigation 82 1229-1239.
-
(2002)
Laboratory Investigation
, vol.82
, pp. 1229-1239
-
-
Yu, W.1
Niwa, T.2
Miura, Y.3
Horio, F.4
Teradaira, S.5
Ribar, T.J.6
Means, A.R.7
Hasegawa, Y.8
Senda, T.9
Niki, I.10
-
38
-
-
33750448469
-
GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress
-
Yusta B, Baggio LL, Estall JL, Koehler JA, Holland DP, Li H, Pipeleers D, Ling Z & Drucker DJ 2006 GLP-1 receptor activation improves beta cell function and survival following induction of endoplasmic reticulum stress. Cell Metabolism 4 391-406.
-
(2006)
Cell Metabolism
, vol.4
, pp. 391-406
-
-
Yusta, B.1
Baggio, L.L.2
Estall, J.L.3
Koehler, J.A.4
Holland, D.P.5
Li, H.6
Pipeleers, D.7
Ling, Z.8
Drucker, D.J.9
|