메뉴 건너뛰기




Volumn 190, Issue 6, 2013, Pages 2603-2613

Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; CD45RB ANTIGEN; CHEMOKINE RECEPTOR CCR9; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 21; INTERLEUKIN 4; INTERLEUKIN 6; RETINOIC ACID; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR BETA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84874925767     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200852     Document Type: Article
Times cited : (15)

References (47)
  • 1
    • 33646165128 scopus 로고    scopus 로고
    • A central role for central tolerance
    • Kyewski, B., and L. Klein. 2006. A central role for central tolerance. Annu. Rev. Immunol. 24: 571-606
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 571-606
    • Kyewski, B.1    Klein, L.2
  • 2
    • 74049160009 scopus 로고    scopus 로고
    • Mechanisms maintaining peripheral tolerance
    • Mueller, D. L. 2010. Mechanisms maintaining peripheral tolerance. Nat. Immunol. 11: 21-27
    • (2010) Nat. Immunol. , vol.11 , pp. 21-27
    • Mueller, D.L.1
  • 3
    • 74049164847 scopus 로고    scopus 로고
    • Regulatory T cells exert checks and balances on self tolerance and autoimmunity
    • Wing, K., and S. Sakaguchi. 2010. Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nat. Immunol. 11: 7-13
    • (2010) Nat. Immunol. , vol.11 , pp. 7-13
    • Wing, K.1    Sakaguchi, S.2
  • 5
    • 27844518834 scopus 로고    scopus 로고
    • Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects
    • Danke, N. A., J. Yang, C. Greenbaum, and W. W. Kwok. 2005. Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects. J. Autoimmun. 25: 303-311
    • (2005) J. Autoimmun. , vol.25 , pp. 303-311
    • Danke, N.A.1    Yang, J.2    Greenbaum, C.3    Kwok, W.W.4
  • 6
    • 0037348923 scopus 로고    scopus 로고
    • CD4 T cell activation by myelin oligodendrocyte glycoprotein is suppressed by adult but not cord blood CD25+ T cells
    • Wing, K., S. Lindgren, G. Kollberg, A. Lundgren, R. A. Harris, A. Rudin, S. Lundin, and E. Suri-Payer. 2003. CD4 T cell activation by myelin oligodendrocyte glycoprotein is suppressed by adult but not cord blood CD25+ T cells. Eur. J. Immunol. 33: 579-587
    • (2003) Eur. J. Immunol. , vol.33 , pp. 579-587
    • Wing, K.1    Lindgren, S.2    Kollberg, G.3    Lundgren, A.4    Harris, R.A.5    Rudin, A.6    Lundin, S.7    Suri-Payer, E.8
  • 8
    • 33747092627 scopus 로고    scopus 로고
    • T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity
    • Zehn, D., and M. J. Bevan. 2006. T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity. Immunity 25: 261-270
    • (2006) Immunity , vol.25 , pp. 261-270
    • Zehn, D.1    Bevan, M.J.2
  • 9
    • 67649170980 scopus 로고    scopus 로고
    • Foxp3+ regulatory T cells: Differentiation, specification, subphenotypes
    • Feuerer, M., J. A. Hill, D. Mathis, and C. Benoist. 2009. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat. Immunol. 10: 689-695
    • (2009) Nat. Immunol. , vol.10 , pp. 689-695
    • Feuerer, M.1    Hill, J.A.2    Mathis, D.3    Benoist, C.4
  • 10
    • 25844504653 scopus 로고    scopus 로고
    • Developmental regulation of Foxp3 expression during ontogeny
    • Fontenot, J. D., J. L. Dooley, A. G. Farr, and A. Y. Rudensky. 2005. Developmental regulation of Foxp3 expression during ontogeny. J. Exp. Med. 202: 901-906
    • (2005) J. Exp. Med. , vol.202 , pp. 901-906
    • Fontenot, J.D.1    Dooley, J.L.2    Farr, A.G.3    Rudensky, A.Y.4
  • 11
    • 75749124604 scopus 로고    scopus 로고
    • Development of thymically derived natural regulatory T cells
    • Bettini, M. L., and D. A. Vignali. 2010. Development of thymically derived natural regulatory T cells. Ann. N. Y. Acad. Sci. 1183: 1-12
    • (2010) Ann. N. Y. Acad. Sci. , vol.1183 , pp. 1-12
    • Bettini, M.L.1    Vignali, D.A.2
  • 12
  • 14
    • 0035399985 scopus 로고    scopus 로고
    • Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
    • Thorstenson, K. M., and A. Khoruts. 2001. Generation of anergic and potentially immunoregulatory CD25+CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J. Immunol. 167: 188-195
    • (2001) J. Immunol. , vol.167 , pp. 188-195
    • Thorstenson, K.M.1    Khoruts, A.2
  • 15
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+ CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
    • Chen, W., W. Jin, N. Hardegen, K. J. Lei, L. Li, N. Marinos, G. McGrady, and S. M. Wahl. 2003. Conversion of peripheral CD4+CD25- naive T cells to CD4+ CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 16
  • 17
    • 38949164425 scopus 로고    scopus 로고
    • Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway
    • Elias, K. M., A. Laurence, T. S. Davidson, G. Stephens, Y. Kanno, E. M. Shevach, and J. J. O'Shea. 2008. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood 111: 1013-1020
    • (2008) Blood , vol.111 , pp. 1013-1020
    • Elias, K.M.1    Laurence, A.2    Davidson, T.S.3    Stephens, G.4    Kanno, Y.5    Shevach, E.M.6    O'Shea, J.J.7
  • 19
    • 53149137849 scopus 로고    scopus 로고
    • Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression
    • Xiao, S., H. Jin, T. Korn, S. M. Liu, M. Oukka, B. Lim, and V. K. Kuchroo. 2008. Retinoic acid increases Foxp3+ regulatory T cells and inhibits development of Th17 cells by enhancing TGF-β-driven Smad3 signaling and inhibiting IL-6 and IL-23 receptor expression. J. Immunol. 181: 2277-2284
    • (2008) J. Immunol. , vol.181 , pp. 2277-2284
    • Xiao, S.1    Jin, H.2    Korn, T.3    Liu, S.M.4    Oukka, M.5    Lim, B.6    Kuchroo, V.K.7
  • 21
    • 77957025756 scopus 로고    scopus 로고
    • Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer i
    • Xu, L., A. Kitani, C. Stuelten, G. McGrady, I. Fuss, and W. Strober. 2010. Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I. Immunity 33: 313- 325
    • (2010) Immunity , vol.33 , pp. 313-325
    • Xu, L.1    Kitani, A.2    Stuelten, C.3    McGrady, G.4    Fuss, I.5    Strober, W.6
  • 22
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun, C. M., J. A. Hall, R. B. Blank, N. Bouladoux, M. Oukka, J. R. Mora, and Y. Belkaid. 2007. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J. Exp. Med. 204: 1775-1785
    • (2007) J. Exp. Med. , vol.204 , pp. 1775-1785
    • Sun, C.M.1    Hall, J.A.2    Blank, R.B.3    Bouladoux, N.4    Oukka, M.5    Mora, J.R.6    Belkaid, Y.7
  • 23
    • 79960843999 scopus 로고    scopus 로고
    • Post-thymic maturation: Young T cells assert their individuality
    • Fink, P. J., and D. W. Hendricks. 2011. Post-thymic maturation: young T cells assert their individuality. Nat. Rev. Immunol. 11: 544-549
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 544-549
    • Fink, P.J.1    Hendricks, D.W.2
  • 25
    • 63049130261 scopus 로고    scopus 로고
    • Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
    • Haines, C. J., T. D. Giffon, L. S. Lu, X. Lu, M. Tessier-Lavigne, D. T. Ross, and D. B. Lewis. 2009. Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function. J. Exp. Med. 206: 275-285
    • (2009) J. Exp. Med. , vol.206 , pp. 275-285
    • Haines, C.J.1    Giffon, T.D.2    Lu, L.S.3    Lu, X.4    Tessier-Lavigne, M.5    Ross, D.T.6    Lewis, D.B.7
  • 26
    • 79251556549 scopus 로고    scopus 로고
    • Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage
    • Hendricks, D. W., and P. J. Fink. 2011. Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage. Blood 117: 1239-1249
    • (2011) Blood , vol.117 , pp. 1239-1249
    • Hendricks, D.W.1    Fink, P.J.2
  • 27
    • 67049088422 scopus 로고    scopus 로고
    • Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants
    • Opiela, S. J., T. Koru-Sengul, and B. Adkins. 2009. Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants. Blood 113: 5635-5643
    • (2009) Blood , vol.113 , pp. 5635-5643
    • Opiela, S.J.1    Koru-Sengul, T.2    Adkins, B.3
  • 28
    • 54049122959 scopus 로고    scopus 로고
    • Cutting edge: Contact with secondary lymphoid organs drives postthymic T cell maturation
    • Houston, E. G., Jr., R. Nechanitzky, and P. J. Fink. 2008. Cutting edge: contact with secondary lymphoid organs drives postthymic T cell maturation. J. Immunol. 181: 5213-5217
    • (2008) J. Immunol. , vol.181 , pp. 5213-5217
    • Houston Jr., E.G.1    Nechanitzky, R.2    Fink, P.J.3
  • 29
    • 84934441392 scopus 로고    scopus 로고
    • Transient deficiencies of T-cellmediated immunity in the neonate
    • Randolph, D. A., and D. B. Lewis. 2006. Transient deficiencies of T-cellmediated immunity in the neonate. Adv. Exp. Med. Biol. 582: 55-69
    • (2006) Adv. Exp. Med. Biol. , vol.582 , pp. 55-69
    • Randolph, D.A.1    Lewis, D.B.2
  • 30
    • 45249101091 scopus 로고    scopus 로고
    • Umbilical cord blood transplantation: Basic biology and clinical challenges to immune reconstitution
    • Brown, J. A., and V. A. Boussiotis. 2008. Umbilical cord blood transplantation: basic biology and clinical challenges to immune reconstitution. Clin. Immunol. 127: 286-297
    • (2008) Clin. Immunol. , vol.127 , pp. 286-297
    • Brown, J.A.1    Boussiotis, V.A.2
  • 31
  • 32
    • 0025697469 scopus 로고
    • Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo
    • Murphy, K. M., A. B. Heimberger, and D. Y. Loh. 1990. Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo. Science 250: 1720-1723
    • (1990) Science , vol.250 , pp. 1720-1723
    • Murphy, K.M.1    Heimberger, A.B.2    Loh, D.Y.3
  • 33
    • 0031897801 scopus 로고    scopus 로고
    • Defective TCR expression in transgenic mice constructed using cDNA-based a- and b-chain genes under the control of heterologous regulatory elements
    • Barnden, M. J., J. Allison, W. R. Heath, and F. R. Carbone. 1998. Defective TCR expression in transgenic mice constructed using cDNA-based a- and b-chain genes under the control of heterologous regulatory elements. Immunol. Cell Biol. 76: 34-40
    • (1998) Immunol. Cell Biol. , vol.76 , pp. 34-40
    • Barnden, M.J.1    Allison, J.2    Heath, W.R.3    Carbone, F.R.4
  • 34
    • 34548764423 scopus 로고    scopus 로고
    • Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
    • Denning, T. L., Y. C. Wang, S. R. Patel, I. R. Williams, and B. Pulendran. 2007. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat. Immunol. 8: 1086-1094
    • (2007) Nat. Immunol. , vol.8 , pp. 1086-1094
    • Denning, T.L.1    Wang, Y.C.2    Patel, S.R.3    Williams, I.R.4    Pulendran, B.5
  • 35
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β and retinoic acid-dependent mechanism
    • Coombes, J. L., K. R. Siddiqui, C. V. Arancibia-Cárcamo, J. Hall, C. M. Sun, Y. Belkaid, and F. Powrie. 2007. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β and retinoic acid-dependent mechanism. J. Exp. Med. 204: 1757-1764
    • (2007) J. Exp. Med. , vol.204 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Cárcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6    Powrie, F.7
  • 36
    • 0033136302 scopus 로고    scopus 로고
    • Thymus and autoimmunity: Production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh, M., T. Takahashi, N. Sakaguchi, Y. Kuniyasu, J. Shimizu, F. Otsuka, and S. Sakaguchi. 1999. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162: 5317-5326
    • (1999) J. Immunol. , vol.162 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3    Kuniyasu, Y.4    Shimizu, J.5    Otsuka, F.6    Sakaguchi, S.7
  • 40
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli, E., Y. Carrier, W. Gao, T. Korn, T. B. Strom, M. Oukka, H. L. Weiner, and V. K. Kuchroo. 2006. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441: 235-238
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3    Korn, T.4    Strom, T.B.5    Oukka, M.6    Weiner, H.L.7    Kuchroo, V.K.8
  • 42
    • 0032983330 scopus 로고    scopus 로고
    • Identification of a novel class of retinoic acid receptor b-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells
    • Li, Y., Y. Hashimoto, A. Agadir, H. Kagechika, and Xk. Zhang. 1999. Identification of a novel class of retinoic acid receptor b-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells. J. Biol. Chem. 274: 15360-15366
    • (1999) J. Biol. Chem. , vol.274 , pp. 15360-15366
    • Li, Y.1    Hashimoto, Y.2    Agadir, A.3    Kagechika, H.4    Zhang, Xk.5
  • 43
    • 0005984244 scopus 로고
    • Actively acquired tolerance of foreign cells
    • Billingham, R. E., L. Brent, and P. B. Medawar. 1953. Actively acquired tolerance of foreign cells. Nature 172: 603-606
    • (1953) Nature , vol.172 , pp. 603-606
    • Billingham, R.E.1    Brent, L.2    Medawar, P.B.3
  • 45
    • 70349671147 scopus 로고    scopus 로고
    • Improving outcomes of cord blood transplantation: HLA matching, cell dose and other graft- and transplantation-related factors
    • Eurocord-Netcord registry and European Blood and Marrow Transplant group
    • Rocha, V., E. Gluckman; Eurocord-Netcord registry and European Blood and Marrow Transplant group. 2009. Improving outcomes of cord blood transplantation: HLA matching, cell dose and other graft- and transplantation-related factors. Br. J. Haematol. 147: 262-274
    • (2009) Br. J. Haematol. , vol.147 , pp. 262-274
    • Rocha, V.1    Gluckman, E.2
  • 46
    • 33646010039 scopus 로고    scopus 로고
    • CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium
    • Staton, T. L., A. Habtezion, M. M. Winslow, T. Sato, P. E. Love, and E. C. Butcher. 2006. CD8+ recent thymic emigrants home to and efficiently repopulate the small intestine epithelium. Nat. Immunol. 7: 482-488
    • (2006) Nat. Immunol. , vol.7 , pp. 482-488
    • Staton, T.L.1    Habtezion, A.2    Winslow, M.M.3    Sato, T.4    Love, P.E.5    Butcher, E.C.6
  • 47
    • 79955120250 scopus 로고    scopus 로고
    • Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool
    • Houston, E. G., Jr., L. E. Higdon, and P. J. Fink. 2011. Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool. Proc. Natl. Acad. Sci. USA 108: 5366-5371
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 5366-5371
    • Houston Jr., E.G.1    Higdon, L.E.2    Fink, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.