Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Ali, Juma A M ^a,b   Tagoe, Daniel N A ^a   Munday, Jane C ^a,c   Donachie, Anne ^a   Morrison, Liam J ^c,d   de Koning, Harry P ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b Al Jabal Al Gharbi University   (Libyan Arab Jamahiriya)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

OROTATE PHOSPHORIBOSYLTRANSFERASE; OROTIDINE 5' PHOSPHATE DECARBOXYLASE; PYRIMIDINE; URIDINE PHOSPHORYLASE;

AFRICAN TRYPANOSOMIASIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUXOTROPHY; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIUM CULTURE; BIOSYNTHESIS; BLOODSTREAM INFECTION; CONTROLLED STUDY; CULTURE MEDIUM; DNA CONTENT; ENZYME ACTIVITY; FEMALE; GROWTH RATE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION;

ANIMAL DISEASES; ANIMALS; BIOLOGICAL TRANSPORT; FEMALE; GENE KNOCKOUT TECHNIQUES; MICE; OROTATE PHOSPHORIBOSYLTRANSFERASE; PYRIMIDINES; STARVATION; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN; URACIL; URIDINE PHOSPHORYLASE;

EID: 84874729704     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058034     Document Type: Article

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