Evaluation of nucleoside hydrolase inhibitors for treatment of african trypanosomiasis

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 5, 2010, Pages 1900-1908

  Berg, Maya ^a   Kohl, Linda ^b   Van Der Veken, Pieter ^a   Joossens, Jurgen ^a   Al Salabi, Mohammed I ^c   Castagna, Valeria ^d   Giannese, Francesca ^d   Cos, Paul ^a   Versées, Wim ^e   Steyaert, Jan ^e   Grellier, Philippe ^b   Haemers, Achiel ^a   Degano, Massimo ^d   Maes, Louis ^a   De Koning, Harry P ^c   Augustyns, Koen ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d SAN RAFFAELE HOSPITAL   (Italy)

^e DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

5' METHYLTHIOADENOSINE PHOSPHORYLASE; ANTIPROTOZOAL AGENT; ARSENIC ACID DERIVATIVE; DIAMIDE; GLYCOSIDASE INHIBITOR; INOSINE DERIVATIVE; MELAMINE; N (9 DEAZA ADENIN 9 YL)METHYL 1,4 DIDEOXY 1,4 IMINO RIBITOL; N ARYLMETHYL SUBSTITUTED IMINORIBITOL DERIVATIVE; NUCLEOSIDASE; NUCLEOSIDE TRANSPORTER; UAMC 00109; UAMC 00115; UAMC 00218; UAMC 00311; UAMC 00312; UAMC 00346; UAMC 00363; UAMC 00375; UNCLASSIFIED DRUG;

AFRICAN TRYPANOSOMIASIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPARASITIC ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS RESISTANCE; DRUG ACTIVITY; DRUG INHIBITION; FEMALE; IC 50; IN VIVO STUDY; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; TRYPANOSOMA BRUCEI; TRYPANOSOMA VIVAX; VALIDATION PROCESS;

ADENOSINE; ANIMALS; ANTIPROTOZOAL AGENTS; CARRIER PROTEINS; GENE KNOCKDOWN TECHNIQUES; MELARSOPROL; MICE; MODELS, CHEMICAL; N-GLYCOSYL HYDROLASES; PENTAMIDINE; RNA, SMALL INTERFERING; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

EID: 77951211334     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01787-09     Document Type: Article

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