Depletion of dimeric all-α dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei

International Journal of Biochemistry and Cell Biology

Volumn 40, Issue 12, 2008, Pages 2901-2913

  Castillo Acosta, Víctor M ^a   Estévez, Antonio M ^a   Vidal, Antonio E ^a   Ruiz Perez, Luis M ^a   González Pacanowska, Dolores ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

Author keywords

Cell cycle; Deoxyuridine triphosphate nucleotidohydrolase; Methotrexate; RNAi; Trypanosoma brucei; Uracil

Indexed keywords

DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA GLYCOSYLTRANSFERASE; METHOTREXATE; THYMIDINE; URACIL;

ANIMAL CELL; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINESIS; DNA REPLICATION; DNA STRAND BREAKAGE; DOWN REGULATION; DRUG HYPERSENSITIVITY; ENZYME ACTIVITY; ENZYME LOCALIZATION; EXCISION REPAIR; NONHUMAN; RNA INTERFERENCE; TRYPANOSOMA BRUCEI;

ANIMALS; CELL CYCLE; DNA DAMAGE; DNA REPAIR; G2 PHASE; PLASMIDS; PYROPHOSPHATASES; RNA INTERFERENCE; S PHASE; THYMINE NUCLEOTIDES; TRANSFECTION; TRYPANOSOMA BRUCEI BRUCEI; URACIL; URACIL NUCLEOTIDES; URACIL-DNA GLYCOSIDASE;

BACTERIA (MICROORGANISMS); EUKARYOTA; TRYPANOSOMA BRUCEI;

EID: 51249096959     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.06.009     Document Type: Article

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