-
1
-
-
0024322942
-
Microglial response to 6-hydroxydopamine-induced substantia nigra lesions
-
2501002 1:STN:280:DyaL1MzgtlGgtA%3D%3D 10.1016/0006-8993(89)90857-3
-
Akiyama H, McGeer PL (1989) Microglial response to 6-hydroxydopamine- induced substantia nigra lesions. Brain Res 489:247-253
-
(1989)
Brain Res
, vol.489
, pp. 247-253
-
-
Akiyama, H.1
McGeer, P.L.2
-
2
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
9282961 1:CAS:528:DyaK2sXls1Chu70%3D 10.1046/j.1471-4159.1997.69031326.x
-
Alam ZI, Daniel SE, Lees AJ, Marsden DC, Jenner P, Halliwell B (1997) A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem 69:1326-1329
-
(1997)
J Neurochem
, vol.69
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, D.C.4
Jenner, P.5
Halliwell, B.6
-
3
-
-
79961160742
-
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
-
21788405 1:CAS:528:DC%2BC3MXhtVSit7rI 10.1084/jem.20102657
-
Anandasabapathy N, Victora GD, Meredith M, Feder R, Dong B, Kluger C, Yao K, Dustin ML, Nussenzweig MC, Steinman RM, Liu K (2011) Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. J Exp Med 208:1695-1705
-
(2011)
J Exp Med
, vol.208
, pp. 1695-1705
-
-
Anandasabapathy, N.1
Victora, G.D.2
Meredith, M.3
Feder, R.4
Dong, B.5
Kluger, C.6
Yao, K.7
Dustin, M.L.8
Nussenzweig, M.C.9
Steinman, R.M.10
Liu, K.11
-
4
-
-
33750907721
-
Peripheral inflammation and neuroprotection: Systemic pretreatment with complete Freund's adjuvant reduces 6-hydroxydopamine toxicity in a rodent model of Parkinson's disease
-
17023164 1:CAS:528:DC%2BD28Xht1Cmt7rO 10.1016/j.nbd.2006.08.016
-
Armentero MT, Levandis G, Nappi G, Bazzini E, Blandini F (2006) Peripheral inflammation and neuroprotection: systemic pretreatment with complete Freund's adjuvant reduces 6-hydroxydopamine toxicity in a rodent model of Parkinson's disease. Neurobiol Dis 24:492-505
-
(2006)
Neurobiol Dis
, vol.24
, pp. 492-505
-
-
Armentero, M.T.1
Levandis, G.2
Nappi, G.3
Bazzini, E.4
Blandini, F.5
-
5
-
-
79960222209
-
Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson's disease
-
21684338 1:CAS:528:DC%2BC3MXptVOjsrw%3D 10.1016/j.nbd.2011.05.017
-
Armentero MT, Levandis G, Bazzini E, Cerri S, Ghezzi C, Blandini F (2011) Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson's disease. Neurobiol Dis 43:663-668
-
(2011)
Neurobiol Dis
, vol.43
, pp. 663-668
-
-
Armentero, M.T.1
Levandis, G.2
Bazzini, E.3
Cerri, S.4
Ghezzi, C.5
Blandini, F.6
-
6
-
-
0036850086
-
Visualising microglial activation in vivo
-
12379908 10.1002/glia.10144
-
Banati RB (2002) Visualising microglial activation in vivo. Glia 40:206-217
-
(2002)
Glia
, vol.40
, pp. 206-217
-
-
Banati, R.B.1
-
7
-
-
2542455543
-
Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure
-
15095370 10.1002/glia.20015
-
Barcia C, Sanchez BA, Fernandez-Villalba E, Bautista V, Poza YP, Fernandez-Barreiro A, Hirsch EC, Herrero MT (2004) Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure. Glia 46:402-409
-
(2004)
Glia
, vol.46
, pp. 402-409
-
-
Barcia, C.1
Sanchez, B.A.2
Fernandez-Villalba, E.3
Bautista, V.4
Poza, Y.P.5
Fernandez-Barreiro, A.6
Hirsch, E.C.7
Herrero, M.T.8
-
8
-
-
84858621036
-
Long-term polarization of microglia upon alpha-synuclein overexpression in nonhuman primates
-
22342967 1:CAS:528:DC%2BC38XksFantLw%3D 10.1016/j.neuroscience.2012.02. 004
-
Barkholt P, Sanchez-Guajardo V, Kirik D, Romero-Ramos M (2012) Long-term polarization of microglia upon alpha-synuclein overexpression in nonhuman primates. Neuroscience 208:85-96
-
(2012)
Neuroscience
, vol.208
, pp. 85-96
-
-
Barkholt, P.1
Sanchez-Guajardo, V.2
Kirik, D.3
Romero-Ramos, M.4
-
9
-
-
36249003354
-
Neuroinflammation in the pathophysiology of Parkinson's disease: Evidence from animal models to human in vivo studies with [11C]-PK11195 PET
-
17592621 10.1002/mds.21552
-
Bartels AL, Leenders KL (2007) Neuroinflammation in the pathophysiology of Parkinson's disease: evidence from animal models to human in vivo studies with [11C]-PK11195 PET. Mov Disord 22:1852-1856
-
(2007)
Mov Disord
, vol.22
, pp. 1852-1856
-
-
Bartels, A.L.1
Leenders, K.L.2
-
10
-
-
74149094597
-
[11C]-PK11195 PET: Quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease?
-
19487152 1:STN:280:DC%2BC3c%2FpvFGgtg%3D%3D 10.1016/j.parkreldis.2009.05. 005
-
Bartels AL, Willemsen AT, Doorduin J, de Vries EF, Dierckx RA, Leenders KL (2010) [11C]-PK11195 PET: quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease? Parkinsonism Relat Disord 16:57-59
-
(2010)
Parkinsonism Relat Disord
, vol.16
, pp. 57-59
-
-
Bartels, A.L.1
Willemsen, A.T.2
Doorduin, J.3
De Vries, E.F.4
Dierckx, R.A.5
Leenders, K.L.6
-
11
-
-
79958116313
-
NSAID use and risk of Parkinson disease: A population-based case-control study
-
21457177 1:STN:280:DC%2BC3Mfpsl2gsA%3D%3D 10.1111/j.1468-1331.2011.03399. x
-
Becker C, Jick SS, Meier CR (2011) NSAID use and risk of Parkinson disease: a population-based case-control study. Eur J Neurol 18:1336-1342
-
(2011)
Eur J Neurol
, vol.18
, pp. 1336-1342
-
-
Becker, C.1
Jick, S.S.2
Meier, C.R.3
-
12
-
-
55749110043
-
CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
-
18809917 1:CAS:528:DC%2BD1cXht1Gnt7rO 10.1073/pnas.0807419105
-
Beers DR, Henkel JS, Zhao W, Wang J, Appel SH (2008) CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc Natl Acad Sci U S A 105:15558-15563
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 15558-15563
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
Wang, J.4
Appel, S.H.5
-
13
-
-
79957528028
-
Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
-
21596768 10.1093/brain/awr074
-
Beers DR, Henkel JS, Zhao W, Wang J, Huang A, Wen S, Liao B, Appel SH (2011) Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis. Brain 134:1293-1314
-
(2011)
Brain
, vol.134
, pp. 1293-1314
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
Wang, J.4
Huang, A.5
Wen, S.6
Liao, B.7
Appel, S.H.8
-
14
-
-
84858652204
-
Misfolded alpha-synuclein and toll-like receptors: Therapeutic targets for Parkinson's disease
-
22166424 10.1016/S1353-8020(11)70008-6
-
Beraud D, Maguire-Zeiss KA (2012) Misfolded alpha-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease. Parkinsonism Relat Disord 18(Suppl 1):S17-S20
-
(2012)
Parkinsonism Relat Disord
, vol.18
, Issue.SUPPL. 1
-
-
Beraud, D.1
Maguire-Zeiss, K.A.2
-
15
-
-
84858677969
-
Alpha-synuclein alters toll-like receptor expression
-
21747756 10.3389/fnins.2011.00080 1:CAS:528:DC%2BC38XjvFWksQ%3D%3D
-
Beraud D, Twomey M, Bloom B, Mittereder A, Ton V, Neitzke K, Chasovskikh S, Mhyre TR, Maguire-Zeiss KA (2011) Alpha-synuclein alters toll-like receptor expression. Front Neurosci 5:80
-
(2011)
Front Neurosci
, vol.5
, pp. 80
-
-
Beraud, D.1
Twomey, M.2
Bloom, B.3
Mittereder, A.4
Ton, V.5
Neitzke, K.6
Chasovskikh, S.7
Mhyre, T.R.8
Maguire-Zeiss, K.A.9
-
16
-
-
84874654334
-
Microglial activation and antioxidant responses induced by the Parkinson's disease protein alpha-synuclein
-
doi: 10.1007/s11481-012-9401-0
-
Beraud D, Hathaway HA, Trecki J, Chasovskikh S, Johnson DA, Johnson JA, Federoff HJ, Shimoji M, Mhyre TR, Maguire-Zeiss KA (2012) Microglial activation and antioxidant responses induced by the Parkinson's disease protein alpha-synuclein. J Neuroimmune Pharmacol. doi: 10.1007/s11481-012-9401-0
-
(2012)
J Neuroimmune Pharmacol
-
-
Beraud, D.1
Hathaway, H.A.2
Trecki, J.3
Chasovskikh, S.4
Johnson, D.A.5
Johnson, J.A.6
Federoff, H.J.7
Shimoji, M.8
Mhyre, T.R.9
Maguire-Zeiss, K.A.10
-
17
-
-
0032842038
-
Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: Implications for Parkinson's disease
-
10461904 1:CAS:528:DyaK1MXlsVOitL4%3D 10.1046/j.1471-4159.1999.0731127.x
-
Berman SB, Hastings TG (1999) Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease. J Neurochem 73:1127-1137
-
(1999)
J Neurochem
, vol.73
, pp. 1127-1137
-
-
Berman, S.B.1
Hastings, T.G.2
-
18
-
-
33747769942
-
Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers
-
16845533 1:CAS:528:DC%2BD28XosFWku7k%3D 10.1007/s00401-006-0104-6
-
Beyer K (2006) Alpha-synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers. Acta Neuropathol 112:237-251
-
(2006)
Acta Neuropathol
, vol.112
, pp. 237-251
-
-
Beyer, K.1
-
19
-
-
0034287012
-
Functional changes of the basal ganglia circuitry in Parkinson's disease
-
10821982 1:CAS:528:DC%2BD3cXltFWnurs%3D 10.1016/S0301-0082(99)00067-2
-
Blandini F, Nappi G, Tassorelli C, Martignoni E (2000) Functional changes of the basal ganglia circuitry in Parkinson's disease. Prog Neurobiol 62:63-88
-
(2000)
Prog Neurobiol
, vol.62
, pp. 63-88
-
-
Blandini, F.1
Nappi, G.2
Tassorelli, C.3
Martignoni, E.4
-
20
-
-
47049116273
-
The 6-hydroxydopamine model: News from the past
-
18595767 10.1016/j.parkreldis.2008.04.015
-
Blandini F, Armentero MT, Martignoni E (2008) The 6-hydroxydopamine model: news from the past. Parkinsonism Relat Disord 14(Suppl 2):S124-S129
-
(2008)
Parkinsonism Relat Disord
, vol.14
, Issue.SUPPL. 2
-
-
Blandini, F.1
Armentero, M.T.2
Martignoni, E.3
-
21
-
-
0028364696
-
Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
-
8084523 1:CAS:528:DyaK2cXkvVSitro%3D 10.1016/0304-3940(94)90684-X
-
Boka G, Anglade P, Wallach D, Javoy-Agid F, Agid Y, Hirsch EC (1994) Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett 172:151-154
-
(1994)
Neurosci Lett
, vol.172
, pp. 151-154
-
-
Boka, G.1
Anglade, P.2
Wallach, D.3
Javoy-Agid, F.4
Agid, Y.5
Hirsch, E.C.6
-
22
-
-
35348875661
-
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
-
17851257 10.1159/000108110
-
Bornebroek M, de Lau LM, Haag MD, Koudstaal PJ, Hofman A, Stricker BH, Breteler MM (2007) Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease. Neuroepidemiology 28:193-196
-
(2007)
Neuroepidemiology
, vol.28
, pp. 193-196
-
-
Bornebroek, M.1
De Lau, L.M.2
Haag, M.D.3
Koudstaal, P.J.4
Hofman, A.5
Stricker, B.H.6
Breteler, M.M.7
-
23
-
-
58849107919
-
Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
-
19104149 1:CAS:528:DC%2BD1MXmtFCgsA%3D%3D
-
Brochard V, Combadiere B, Prigent A, Laouar Y, Perrin A, Beray-Berthat V, Bonduelle O, Alvarez-Fischer D, Callebert J, Launay JM, Duyckaerts C, Flavell RA, Hirsch EC, Hunot S (2009) Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. J Clin Invest 119:182-192
-
(2009)
J Clin Invest
, vol.119
, pp. 182-192
-
-
Brochard, V.1
Combadiere, B.2
Prigent, A.3
Laouar, Y.4
Perrin, A.5
Beray-Berthat, V.6
Bonduelle, O.7
Alvarez-Fischer, D.8
Callebert, J.9
Launay, J.M.10
Duyckaerts, C.11
Flavell, R.A.12
Hirsch, E.C.13
Hunot, S.14
-
24
-
-
46749085399
-
Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFalpha, and INFgamma concentrations are elevated in patients with atypical and idiopathic parkinsonism
-
18582534 1:CAS:528:DC%2BD1cXosVOgtLk%3D 10.1016/j.neulet.2008.06.040
-
Brodacki B, Staszewski J, Toczylowska B, Kozlowska E, Drela N, Chalimoniuk M, Stepien A (2008) Serum interleukin (IL-2, IL-10, IL-6, IL-4), TNFalpha, and INFgamma concentrations are elevated in patients with atypical and idiopathic parkinsonism. Neurosci Lett 441:158-162
-
(2008)
Neurosci Lett
, vol.441
, pp. 158-162
-
-
Brodacki, B.1
Staszewski, J.2
Toczylowska, B.3
Kozlowska, E.4
Drela, N.5
Chalimoniuk, M.6
Stepien, A.7
-
25
-
-
77957347060
-
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro
-
20798282 1:CAS:528:DC%2BC3cXhtFOqsrvN 10.1126/science.1195227
-
Burre J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Sudhof TC (2010) Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science 329:1663-1667
-
(2010)
Science
, vol.329
, pp. 1663-1667
-
-
Burre, J.1
Sharma, M.2
Tsetsenis, T.3
Buchman, V.4
Etherton, M.R.5
Sudhof, T.C.6
-
26
-
-
25844442898
-
6-Hydroxydopamine-induced alterations in blood-brain barrier permeability
-
16176358 1:STN:280:DC%2BD2MrgsVKgsQ%3D%3D 10.1111/j.1460-9568.2005.04281. x
-
Carvey PM, Zhao CH, Hendey B, Lum H, Trachtenberg J, Desai BS, Snyder J, Zhu YG, Ling ZD (2005) 6-Hydroxydopamine-induced alterations in blood-brain barrier permeability. Eur J Neurosci 22:1158-1168
-
(2005)
Eur J Neurosci
, vol.22
, pp. 1158-1168
-
-
Carvey, P.M.1
Zhao, C.H.2
Hendey, B.3
Lum, H.4
Trachtenberg, J.5
Desai, B.S.6
Snyder, J.7
Zhu, Y.G.8
Ling, Z.D.9
-
27
-
-
79952599788
-
Association of GWAS loci with PD in China
-
21268244
-
Chang XL, Mao XY, Li HH, Zhang JH, Li NN, Burgunder JM, Peng R, Tan EK (2011) Association of GWAS loci with PD in China. Am J Med Genet B Neuropsychiatr Genet 156B:334-339
-
(2011)
Am J Med Genet B Neuropsychiatr Genet
, vol.156
, pp. 334-339
-
-
Chang, X.L.1
Mao, X.Y.2
Li, H.H.3
Zhang, J.H.4
Li, N.N.5
Burgunder, J.M.6
Peng, R.7
Tan, E.K.8
-
28
-
-
17844406856
-
Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
-
15834418 1:CAS:528:DC%2BD2MXjsFyktL0%3D 10.1038/nn1443
-
Chen L, Feany MB (2005) Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat Neurosci 8:657-663
-
(2005)
Nat Neurosci
, vol.8
, pp. 657-663
-
-
Chen, L.1
Feany, M.B.2
-
29
-
-
0041653249
-
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
-
12925360 10.1001/archneur.60.8.1059
-
Chen H, Zhang SM, Hernan MA, Schwarzschild MA, Willett WC, Colditz GA, Speizer FE, Ascherio A (2003) Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease. Arch Neurol 60:1059-1064
-
(2003)
Arch Neurol
, vol.60
, pp. 1059-1064
-
-
Chen, H.1
Zhang, S.M.2
Hernan, M.A.3
Schwarzschild, M.A.4
Willett, W.C.5
Colditz, G.A.6
Speizer, F.E.7
Ascherio, A.8
-
30
-
-
70449347241
-
Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation
-
19855133 1:CAS:528:DC%2BD1MXntVCjtLs%3D 10.1172/JCI35314
-
Chen L, Periquet M, Wang X, Negro A, McLean PJ, Hyman BT, Feany MB (2009) Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. J Clin Invest 119:3257-3265
-
(2009)
J Clin Invest
, vol.119
, pp. 3257-3265
-
-
Chen, L.1
Periquet, M.2
Wang, X.3
Negro, A.4
McLean, P.J.5
Hyman, B.T.6
Feany, M.B.7
-
31
-
-
44249092075
-
Nonmotor symptoms of Parkinson's disease: Prevalence and awareness of patients and families
-
18042421 10.1016/j.parkreldis.2007.09.002
-
Cheon SM, Ha MS, Park MJ, Kim JW (2008) Nonmotor symptoms of Parkinson's disease: prevalence and awareness of patients and families. Parkinsonism Relat Disord 14:286-290
-
(2008)
Parkinsonism Relat Disord
, vol.14
, pp. 286-290
-
-
Cheon, S.M.1
Ha, M.S.2
Park, M.J.3
Kim, J.W.4
-
32
-
-
77957358299
-
Mitochondrial dynamics in cell death and neurodegeneration
-
20577776 1:CAS:528:DC%2BC3cXhtFOrtb7E 10.1007/s00018-010-0435-2
-
Cho DH, Nakamura T, Lipton SA (2010) Mitochondrial dynamics in cell death and neurodegeneration. Cell Mol Life Sci 67:3435-3447
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3435-3447
-
-
Cho, D.H.1
Nakamura, T.2
Lipton, S.A.3
-
33
-
-
0036459335
-
Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging
-
11918659 1:STN:280:DC%2BD383ksVSjuw%3D%3D 10.1046/j.1460-9568.2002.01938. x
-
Cicchetti F, Brownell AL, Williams K, Chen YI, Livni E, Isacson O (2002) Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging. Eur J Neurosci 15:991-998
-
(2002)
Eur J Neurosci
, vol.15
, pp. 991-998
-
-
Cicchetti, F.1
Brownell, A.L.2
Williams, K.3
Chen, Y.I.4
Livni, E.5
Isacson, O.6
-
34
-
-
84874664078
-
Immune heterogeneity in neuroinflammation: Dendritic cells in the brain
-
doi: 10.1007/s11481-012-9414-8
-
Colton CA (2012) Immune heterogeneity in neuroinflammation: dendritic cells in the brain. J Neuroimmune Pharmacol. doi: 10.1007/s11481-012-9414-8
-
(2012)
J Neuroimmune Pharmacol
-
-
Colton, C.A.1
-
36
-
-
27344438938
-
Microglial inflammation in the parkinsonian substantia nigra: Relationship to alpha-synuclein deposition
-
15935098 10.1186/1742-2094-2-14 1:CAS:528:DC%2BD2MXhtFWls7zK
-
Croisier E, Moran LB, Dexter DT, Pearce RK, Graeber MB (2005) Microglial inflammation in the parkinsonian substantia nigra: relationship to alpha-synuclein deposition. J Neuroinflammation 2:14
-
(2005)
J Neuroinflammation
, vol.2
, pp. 14
-
-
Croisier, E.1
Moran, L.B.2
Dexter, D.T.3
Pearce, R.K.4
Graeber, M.B.5
-
37
-
-
77953463398
-
Protein degradation, aggregation, and misfolding
-
20187257 10.1002/mds.22718
-
Cuervo AM, Wong ES, Martinez-Vicente M (2010) Protein degradation, aggregation, and misfolding. Mov Disord 25(Suppl 1):S49-S54
-
(2010)
Mov Disord
, vol.25
, Issue.SUPPL. 1
-
-
Cuervo, A.M.1
Wong, E.S.2
Martinez-Vicente, M.3
-
38
-
-
0030175757
-
Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) induced Parkinson's disease mice model
-
8819134 1:STN:280:DyaK28vhs1ahug%3D%3D 10.1006/neur.1996.0020
-
Czlonkowska A, Kohutnicka M, Kurkowska-Jastrzebska I, Czlonkowski A (1996) Microglial reaction in MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) induced Parkinson's disease mice model. Neurodegeneration 5:137-143
-
(1996)
Neurodegeneration
, vol.5
, pp. 137-143
-
-
Czlonkowska, A.1
Kohutnicka, M.2
Kurkowska-Jastrzebska, I.3
Czlonkowski, A.4
-
39
-
-
0031013848
-
Prevalence of parkinsonism and Parkinson's disease in Europe: The EUROPARKINSON Collaborative Study. European Community concerted action on the epidemiology of Parkinson's disease
-
9010393 10.1136/jnnp.62.1.10
-
de Rijk MC, Tzourio C, Breteler MM, Dartigues JF, Amaducci L, Lopez-Pousa S, Manubens-Bertran JM, Alperovitch A, Rocca WA (1997) Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community concerted action on the epidemiology of Parkinson's disease. J Neurol Neurosurg Psychiatry 62:10-15
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.62
, pp. 10-15
-
-
De Rijk, M.C.1
Tzourio, C.2
Breteler, M.M.3
Dartigues, J.F.4
Amaducci, L.5
Lopez-Pousa, S.6
Manubens-Bertran, J.M.7
Alperovitch, A.8
Rocca, W.A.9
-
40
-
-
79251536194
-
Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: Nested case-control study
-
21252104 10.1136/bmj.d198
-
Driver JA, Logroscino G, Lu L, Gaziano JM, Kurth T (2011) Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: nested case-control study. BMJ 342:d198
-
(2011)
BMJ
, vol.342
, pp. 198
-
-
Driver, J.A.1
Logroscino, G.2
Lu, L.3
Gaziano, J.M.4
Kurth, T.5
-
41
-
-
84858072878
-
Comparison of polarization properties of human adult microglia and blood-derived macrophages
-
22290798 10.1002/glia.22298
-
Durafourt BA, Moore CS, Zammit DA, Johnson TA, Zaguia F, Guiot MC, Bar-Or A, Antel JP (2012) Comparison of polarization properties of human adult microglia and blood-derived macrophages. Glia 60:717-727
-
(2012)
Glia
, vol.60
, pp. 717-727
-
-
Durafourt, B.A.1
Moore, C.S.2
Zammit, D.A.3
Johnson, T.A.4
Zaguia, F.5
Guiot, M.C.6
Bar-Or, A.7
Antel, J.P.8
-
42
-
-
41549133855
-
Non-steroidal anti-inflammatory drug use and the risk of Parkinson disease: A retrospective cohort study
-
18343119 1:CAS:528:DC%2BD1cXktlCkurw%3D 10.1016/j.jocn.2007.02.095
-
Etminan M, Carleton BC, Samii A (2008) Non-steroidal anti-inflammatory drug use and the risk of Parkinson disease: a retrospective cohort study. J Clin Neurosci 15:576-577
-
(2008)
J Clin Neurosci
, vol.15
, pp. 576-577
-
-
Etminan, M.1
Carleton, B.C.2
Samii, A.3
-
43
-
-
0028891650
-
Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse striatum
-
7535890 1:CAS:528:DyaK2MXivFyltrc%3D 10.1016/0892-0362(94)00048-I
-
Francis JW, Von Visger J, Markelonis GJ, Oh TH (1995) Neuroglial responses to the dopaminergic neurotoxicant 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in mouse striatum. Neurotoxicol Teratol 17:7-12
-
(1995)
Neurotoxicol Teratol
, vol.17
, pp. 7-12
-
-
Francis, J.W.1
Von Visger, J.2
Markelonis, G.J.3
Oh, T.H.4
-
44
-
-
78349236177
-
What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?
-
20922807 10.1002/mds.23394
-
Gallagher DA, Lees AJ, Schrag A (2010) What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them? Mov Disord 25:2493-2500
-
(2010)
Mov Disord
, vol.25
, pp. 2493-2500
-
-
Gallagher, D.A.1
Lees, A.J.2
Schrag, A.3
-
45
-
-
76249095169
-
Development of monocytes, macrophages, and dendritic cells
-
20133564 1:CAS:528:DC%2BC3cXhtlyhsrw%3D 10.1126/science.1178331
-
Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K (2010) Development of monocytes, macrophages, and dendritic cells. Science 327:656-661
-
(2010)
Science
, vol.327
, pp. 656-661
-
-
Geissmann, F.1
Manz, M.G.2
Jung, S.3
Sieweke, M.H.4
Merad, M.5
Ley, K.6
-
46
-
-
84855912837
-
Neuroprotective activities of regulatory T cells
-
21996344 10.1016/j.molmed.2011.08.005
-
Gendelman HE, Appel SH (2011) Neuroprotective activities of regulatory T cells. Trends Mol Med 17:687-688
-
(2011)
Trends Mol Med
, vol.17
, pp. 687-688
-
-
Gendelman, H.E.1
Appel, S.H.2
-
47
-
-
30744472146
-
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
-
16182554 1:CAS:528:DC%2BD28XmsVGmsg%3D%3D 10.1016/j.nbd.2005.08.002
-
Gerhard A, Pavese N, Hotton G, Turkheimer F, Es M, Hammers A, Eggert K, Oertel W, Banati RB, Brooks DJ (2006) In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease. Neurobiol Dis 21:404-412
-
(2006)
Neurobiol Dis
, vol.21
, pp. 404-412
-
-
Gerhard, A.1
Pavese, N.2
Hotton, G.3
Turkheimer, F.4
Es, M.5
Hammers, A.6
Eggert, K.7
Oertel, W.8
Banati, R.B.9
Brooks, D.J.10
-
49
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
11062131 1:CAS:528:DC%2BD3cXnvVWkurY%3D 10.1126/science.290.5493.985
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 290:985-989
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
50
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
20303880 1:CAS:528:DC%2BC3cXlsVSgu7Y%3D 10.1016/j.cell.2010.02.016
-
Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140:918-934
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
51
-
-
0037265240
-
Alternative activation of macrophages
-
12511873 1:CAS:528:DC%2BD3sXovVw%3D 10.1038/nri978
-
Gordon S (2003) Alternative activation of macrophages. Nat Rev Immunol 3:23-35
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
52
-
-
2442636348
-
Biomedicine. Parkinson's-divergent causes, convergent mechanisms
-
15155938 1:CAS:528:DC%2BD2cXkt1Kjt78%3D 10.1126/science.1098966
-
Greenamyre JT, Hastings TG (2004) Biomedicine. Parkinson's-divergent causes, convergent mechanisms. Science 304:1120-1122
-
(2004)
Science
, vol.304
, pp. 1120-1122
-
-
Greenamyre, J.T.1
Hastings, T.G.2
-
53
-
-
84866768467
-
Extracellular signal-regulated kinase is involved in alpha-synuclein- induced mitochondrial dynamic disorders by regulating dynamin-like protein 1
-
Gui YX, Wang XY, Kang WY, Zhang YJ, Zhang Y, Zhou Y, Quinn TJ, Liu J, Chen SD (2012) Extracellular signal-regulated kinase is involved in alpha-synuclein-induced mitochondrial dynamic disorders by regulating dynamin-like protein 1. Neurobiol Aging
-
(2012)
Neurobiol Aging
-
-
Gui, Y.X.1
Wang, X.Y.2
Kang, W.Y.3
Zhang, Y.J.4
Zhang, Y.5
Zhou, Y.6
Quinn, T.J.7
Liu, J.8
Chen, S.D.9
-
54
-
-
18144406539
-
Oxidative stress and inflammation in Parkinson's disease: Is there a causal link?
-
15869932 1:CAS:528:DC%2BD2MXjslKjtbo%3D 10.1016/j.expneurol.2005.01.013
-
Hald A, Lotharius J (2005) Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Exp Neurol 193:279-290
-
(2005)
Exp Neurol
, vol.193
, pp. 279-290
-
-
Hald, A.1
Lotharius, J.2
-
55
-
-
77956646167
-
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
-
20711177 1:CAS:528:DC%2BC3cXhtVaisL7J 10.1038/ng.642
-
Hamza TH, Zabetian CP, Tenesa A, Laederach A, Montimurro J, Yearout D, Kay DM, Doheny KF, Paschall J, Pugh E, Kusel VI, Collura R, Roberts J, Griffith A, Samii A, Scott WK, Nutt J, Factor SA, Payami H (2010) Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease. Nat Genet 42:781-785
-
(2010)
Nat Genet
, vol.42
, pp. 781-785
-
-
Hamza, T.H.1
Zabetian, C.P.2
Tenesa, A.3
Laederach, A.4
Montimurro, J.5
Yearout, D.6
Kay, D.M.7
Doheny, K.F.8
Paschall, J.9
Pugh, E.10
Kusel, V.I.11
Collura, R.12
Roberts, J.13
Griffith, A.14
Samii, A.15
Scott, W.K.16
Nutt, J.17
Factor, S.A.18
Payami, H.19
-
56
-
-
35548986304
-
Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
-
17965659 1:CAS:528:DC%2BD2sXht1ajsbbE 10.1038/nn1997
-
Hanisch UK, Kettenmann H (2007) Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 10:1387-1394
-
(2007)
Nat Neurosci
, vol.10
, pp. 1387-1394
-
-
Hanisch, U.K.1
Kettenmann, H.2
-
57
-
-
0022403289
-
Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: Implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity
-
3912685 1:STN:280:DyaL287kslCrug%3D%3D 10.1016/0304-3940(85)90580-4
-
Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC (1985) Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2, 3,6-tetrahydropyridine toxicity. Neurosci Lett 62:389-394
-
(1985)
Neurosci Lett
, vol.62
, pp. 389-394
-
-
Heikkila, R.E.1
Nicklas, W.J.2
Vyas, I.3
Duvoisin, R.C.4
-
58
-
-
62549133546
-
Neuroinflammation in Parkinson's disease: A target for neuroprotection?
-
19296921 1:CAS:528:DC%2BD1MXks1Sis70%3D 10.1016/S1474-4422(09)70062-6
-
Hirsch EC, Hunot S (2009) Neuroinflammation in Parkinson's disease: a target for neuroprotection? Lancet Neurol 8:382-397
-
(2009)
Lancet Neurol
, vol.8
, pp. 382-397
-
-
Hirsch, E.C.1
Hunot, S.2
-
59
-
-
84865967984
-
Aspects of innate immunity and Parkinson's disease
-
22408621 1:CAS:528:DC%2BC38XltF2ltb8%3D 10.3389/fphar.2012.00033
-
Huang Y, Halliday GM (2012) Aspects of innate immunity and Parkinson's disease. Front Pharmacol 3:33
-
(2012)
Front Pharmacol
, vol.3
, pp. 33
-
-
Huang, Y.1
Halliday, G.M.2
-
60
-
-
58449106639
-
Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: Frequency, phenotype, and mechanisms
-
19139307 10.1001/archneurol.2008.555
-
Ibanez P, Lesage S, Janin S, Lohmann E, Durif F, Destee A, Bonnet AM, Brefel-Courbon C, Heath S, Zelenika D, Agid Y, Durr A, Brice A (2009) Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms. Arch Neurol 66:102-108
-
(2009)
Arch Neurol
, vol.66
, pp. 102-108
-
-
Ibanez, P.1
Lesage, S.2
Janin, S.3
Lohmann, E.4
Durif, F.5
Destee, A.6
Bonnet, A.M.7
Brefel-Courbon, C.8
Heath, S.9
Zelenika, D.10
Agid, Y.11
Durr, A.12
Brice, A.13
-
61
-
-
0000340348
-
Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
-
3872460 1:CAS:528:DyaL2MXktVWltbk%3D 10.1073/pnas.82.7.2173
-
Javitch JA, D'Amato RJ, Strittmatter SM, Snyder SH (1985) Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc Natl Acad Sci U S A 82:2173-2177
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 2173-2177
-
-
Javitch, J.A.1
D'Amato, R.J.2
Strittmatter, S.M.3
Snyder, S.H.4
-
62
-
-
0026348872
-
Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway
-
1958262 1:CAS:528:DyaK38XkvVOmt7g%3D 10.1007/BF03159935
-
Jellinger KA (1991) Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway. Mol Chem Neuropathol 14:153-197
-
(1991)
Mol Chem Neuropathol
, vol.14
, pp. 153-197
-
-
Jellinger, K.A.1
-
63
-
-
0036048876
-
Recent developments in the pathology of Parkinson's disease
-
Jellinger KA (2002) Recent developments in the pathology of Parkinson's disease. J Neural Transm 62(Suppl):347-376
-
(2002)
J Neural Transm
, vol.62
, Issue.SUPPL.
, pp. 347-376
-
-
Jellinger, K.A.1
-
64
-
-
0029751104
-
Oxidative stress and the pathogenesis of Parkinson's disease
-
8959985 1:STN:280:DyaK2s7hvFWlsA%3D%3D 10.1212/WNL.47.6-Suppl-3.161S
-
Jenner P, Olanow CW (1996) Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47:S161-S170
-
(1996)
Neurology
, vol.47
-
-
Jenner, P.1
Olanow, C.W.2
-
65
-
-
0026635461
-
Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group
-
1510385 1:CAS:528:DyaK3sXnvVSntQ%3D%3D 10.1002/ana.410320714
-
Jenner P, Dexter DT, Sian J, Schapira AH, Marsden CD (1992) Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol 32(Suppl):S82-S87
-
(1992)
Ann Neurol
, vol.32
, Issue.SUPPL.
-
-
Jenner, P.1
Dexter, D.T.2
Sian, J.3
Schapira, A.H.4
Marsden, C.D.5
-
66
-
-
40849118624
-
Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia
-
17166628 1:CAS:528:DC%2BD1cXktVKnsrk%3D 10.1016/j.neurobiolaging.2006.11. 013
-
Klegeris A, Pelech S, Giasson BI, Maguire J, Zhang H, McGeer EG, McGeer PL (2008) Alpha-synuclein activates stress signaling protein kinases in THP-1 cells and microglia. Neurobiol Aging 29:739-752
-
(2008)
Neurobiol Aging
, vol.29
, pp. 739-752
-
-
Klegeris, A.1
Pelech, S.2
Giasson, B.I.3
Maguire, J.4
Zhang, H.5
McGeer, E.G.6
McGeer, P.L.7
-
67
-
-
79960784323
-
Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity
-
21845170 10.3390/ijerph8072980
-
Kraft AD, Harry GJ (2011) Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity. Int J Environ Res Public Health 8:2980-3018
-
(2011)
Int J Environ Res Public Health
, vol.8
, pp. 2980-3018
-
-
Kraft, A.D.1
Harry, G.J.2
-
68
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
9462735 1:CAS:528:DyaK1cXosFCntA%3D%3D 10.1038/ng0298-106
-
Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, Kosel S, Przuntek H, Epplen JT, Schols L, Riess O (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18:106-108
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
69
-
-
0344528794
-
The inflammatory reaction following 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine intoxication in mouse
-
10192776 1:CAS:528:DyaK1MXis1equrk%3D 10.1006/exnr.1998.6993
-
Kurkowska-Jastrzebska I, Wronska A, Kohutnicka M, Czlonkowski A, Czlonkowska A (1999) The inflammatory reaction following 1-methyl-4-phenyl-1,2, 3, 6-tetrahydropyridine intoxication in mouse. Exp Neurol 156:50-61
-
(1999)
Exp Neurol
, vol.156
, pp. 50-61
-
-
Kurkowska-Jastrzebska, I.1
Wronska, A.2
Kohutnicka, M.3
Czlonkowski, A.4
Czlonkowska, A.5
-
70
-
-
0020680904
-
Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
-
6823561 1:STN:280:DyaL3s7hvF2mtg%3D%3D 10.1126/science.6823561
-
Langston JW, Ballard P, Tetrud JW, Irwin I (1983) Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219:979-980
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
71
-
-
0032829070
-
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
-
10514096 1:CAS:528:DyaK1MXmvVGitbg%3D 10.1002/1531-8249(199910)46: 4<598: AID-ANA7>3.0.CO;2-F
-
Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D (1999) Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 46:598-605
-
(1999)
Ann Neurol
, vol.46
, pp. 598-605
-
-
Langston, J.W.1
Forno, L.S.2
Tetrud, J.3
Reeves, A.G.4
Kaplan, J.A.5
Karluk, D.6
-
72
-
-
33846794644
-
CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease
-
17196666 1:CAS:528:DC%2BD2sXhs1Citbk%3D 10.1016/j.jneuroim.2006.11.009
-
Laurie C, Reynolds A, Coskun O, Bowman E, Gendelman HE, Mosley RL (2007) CD4+ T cells from Copolymer-1 immunized mice protect dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neuroimmunol 183:60-68
-
(2007)
J Neuroimmunol
, vol.183
, pp. 60-68
-
-
Laurie, C.1
Reynolds, A.2
Coskun, O.3
Bowman, E.4
Gendelman, H.E.5
Mosley, R.L.6
-
73
-
-
33846460819
-
Mitochondria mass is low in mouse substantia nigra dopamine neurons: Implications for Parkinson's disease
-
17010972 1:CAS:528:DC%2BD2sXhtVKnt7g%3D 10.1016/j.expneurol.2006.08.015
-
Liang CL, Wang TT, Luby-Phelps K, German DC (2007) Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease. Exp Neurol 203:370-380
-
(2007)
Exp Neurol
, vol.203
, pp. 370-380
-
-
Liang, C.L.1
Wang, T.T.2
Luby-Phelps, K.3
German, D.C.4
-
74
-
-
77953457744
-
The nonmotor symptoms of Parkinson's disease-an overview
-
20187234 10.1002/mds.22786
-
Lim SY, Lang AE (2010) The nonmotor symptoms of Parkinson's disease-an overview. Mov Disord 25(Suppl 1):S123-S130
-
(2010)
Mov Disord
, vol.25
, Issue.SUPPL. 1
-
-
Lim, S.Y.1
Lang, A.E.2
-
75
-
-
79960981876
-
Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population
-
21812969 1:CAS:528:DC%2BC3MXhtFajtLvF 10.1186/1471-2350-12-104
-
Liu X, Cheng R, Verbitsky M, Kisselev S, Browne A, Mejia-Sanatana H, Louis ED, Cote LJ, Andrews H, Waters C, Ford B, Frucht S, Fahn S, Marder K, Clark LN, Lee JH (2011) Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population. BMC Med Genet 12:104
-
(2011)
BMC Med Genet
, vol.12
, pp. 104
-
-
Liu, X.1
Cheng, R.2
Verbitsky, M.3
Kisselev, S.4
Browne, A.5
Mejia-Sanatana, H.6
Louis, E.D.7
Cote, L.J.8
Andrews, H.9
Waters, C.10
Ford, B.11
Frucht, S.12
Fahn, S.13
Marder, K.14
Clark, L.N.15
Lee, J.H.16
-
76
-
-
0037127197
-
The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: Paraquat and alpha-synuclein
-
11707429 1:CAS:528:DC%2BD38XosFaquw%3D%3D 10.1074/jbc.C100560200
-
Manning-Bog AB, McCormack AL, Li J, Uversky VN, Fink AL, Di Monte DA (2002) The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein. J Biol Chem 277:1641-1644
-
(2002)
J Biol Chem
, vol.277
, pp. 1641-1644
-
-
Manning-Bog, A.B.1
McCormack, A.L.2
Li, J.3
Uversky, V.N.4
Fink, A.L.5
Di Monte, D.A.6
-
77
-
-
67650432423
-
Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: A time course study in a 6-hydroxydopamine model of Parkinson's disease
-
19549006 1:CAS:528:DC%2BD1MXptlensL8%3D 10.1111/j.1471-4159.2009.06189.x
-
Marinova-Mutafchieva L, Sadeghian M, Broom L, Davis JB, Medhurst AD, Dexter DT (2009) Relationship between microglial activation and dopaminergic neuronal loss in the substantia nigra: a time course study in a 6-hydroxydopamine model of Parkinson's disease. J Neurochem 110:966-975
-
(2009)
J Neurochem
, vol.110
, pp. 966-975
-
-
Marinova-Mutafchieva, L.1
Sadeghian, M.2
Broom, L.3
Davis, J.B.4
Medhurst, A.D.5
Dexter, D.T.6
-
78
-
-
34548822734
-
The role of anti-inflammatory agents in Parkinson's disease
-
17850169 1:CAS:528:DC%2BD2sXht1yiu7fM 10.2165/00023210-200721100-00001
-
McGeer EG, McGeer PL (2007) The role of anti-inflammatory agents in Parkinson's disease. CNS Drugs 21:789-797
-
(2007)
CNS Drugs
, vol.21
, pp. 789-797
-
-
McGeer, E.G.1
McGeer, P.L.2
-
79
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
-
3399080 1:STN:280:DyaL1c3ovVKkuw%3D%3D 10.1212/WNL.38.8.1285
-
McGeer PL, Itagaki S, Boyes BE, McGeer EG (1988) Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38:1285-1291
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
80
-
-
0242384667
-
Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration
-
14595649 1:CAS:528:DC%2BD3sXpsFChsLk%3D 10.1002/ana.10728
-
McGeer PL, Schwab C, Parent A, Doudet D (2003) Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine administration. Ann Neurol 54:599-604
-
(2003)
Ann Neurol
, vol.54
, pp. 599-604
-
-
McGeer, P.L.1
Schwab, C.2
Parent, A.3
Doudet, D.4
-
81
-
-
30444443297
-
Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys
-
16336966 1:CAS:528:DC%2BD28XksVKgsA%3D%3D 10.1016/j.expneurol.2005.10.034
-
Miklossy J, Doudet DD, Schwab C, Yu S, McGeer EG, McGeer PL (2006) Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys. Exp Neurol 197:275-283
-
(2006)
Exp Neurol
, vol.197
, pp. 275-283
-
-
Miklossy, J.1
Doudet, D.D.2
Schwab, C.3
Yu, S.4
McGeer, E.G.5
McGeer, P.L.6
-
82
-
-
0032738677
-
The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease
-
10658622 1:CAS:528:DyaK1MXnslGmu7o%3D 10.1016/S0306-4522(99)00455-8
-
Mirza B, Hadberg H, Thomsen P, Moos T (2000) The absence of reactive astrocytosis is indicative of a unique inflammatory process in Parkinson's disease. Neuroscience 95:425-432
-
(2000)
Neuroscience
, vol.95
, pp. 425-432
-
-
Mirza, B.1
Hadberg, H.2
Thomsen, P.3
Moos, T.4
-
83
-
-
0028171374
-
Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients
-
7700568 1:CAS:528:DyaK2cXmvFygtLk%3D 10.1016/0304-3940(94)90508-8
-
Mogi M, Harada M, Kondo T, Riederer P, Inagaki H, Minami M, Nagatsu T (1994a) Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients. Neurosci Lett 180:147-150
-
(1994)
Neurosci Lett
, vol.180
, pp. 147-150
-
-
Mogi, M.1
Harada, M.2
Kondo, T.3
Riederer, P.4
Inagaki, H.5
Minami, M.6
Nagatsu, T.7
-
84
-
-
0028178281
-
Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients
-
8015728 1:CAS:528:DyaK2cXitFCqsbY%3D 10.1016/0304-3940(94)90746-3
-
Mogi M, Harada M, Riederer P, Narabayashi H, Fujita K, Nagatsu T (1994b) Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. Neurosci Lett 165:208-210
-
(1994)
Neurosci Lett
, vol.165
, pp. 208-210
-
-
Mogi, M.1
Harada, M.2
Riederer, P.3
Narabayashi, H.4
Fujita, K.5
Nagatsu, T.6
-
85
-
-
0028980156
-
Transforming growth factor-beta 1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease
-
7478158 1:CAS:528:DyaK2MXmvVelu7s%3D 10.1016/0304-3940(95)11686-Q
-
Mogi M, Harada M, Kondo T, Narabayashi H, Riederer P, Nagatsu T (1995) Transforming growth factor-beta 1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease. Neurosci Lett 193:129-132
-
(1995)
Neurosci Lett
, vol.193
, pp. 129-132
-
-
Mogi, M.1
Harada, M.2
Kondo, T.3
Narabayashi, H.4
Riederer, P.5
Nagatsu, T.6
-
87
-
-
39549095825
-
Nonmotor symptoms as presenting complaints in Parkinson's disease: A clinicopathological study
-
17994582 10.1002/mds.21813
-
O'Sullivan SS, Williams DR, Gallagher DA, Massey LA, Silveira-Moriyama L, Lees AJ (2008) Nonmotor symptoms as presenting complaints in Parkinson's disease: a clinicopathological study. Mov Disord 23:101-106
-
(2008)
Mov Disord
, vol.23
, pp. 101-106
-
-
O'Sullivan, S.S.1
Williams, D.R.2
Gallagher, D.A.3
Massey, L.A.4
Silveira-Moriyama, L.5
Lees, A.J.6
-
88
-
-
13144258735
-
Microglial activation and dopamine terminal loss in early Parkinson's disease
-
15668962 1:CAS:528:DC%2BD2MXhs1Cisb8%3D 10.1002/ana.20338
-
Ouchi Y, Yoshikawa E, Sekine Y, Futatsubashi M, Kanno T, Ogusu T, Torizuka T (2005) Microglial activation and dopamine terminal loss in early Parkinson's disease. Ann Neurol 57:168-175
-
(2005)
Ann Neurol
, vol.57
, pp. 168-175
-
-
Ouchi, Y.1
Yoshikawa, E.2
Sekine, Y.3
Futatsubashi, M.4
Kanno, T.5
Ogusu, T.6
Torizuka, T.7
-
89
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
2557792 10.1002/ana.410260606
-
Parker WD Jr, Boyson SJ, Parks JK (1989) Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol 26:719-723
-
(1989)
Ann Neurol
, vol.26
, pp. 719-723
-
-
Parker Jr., W.D.1
Boyson, S.J.2
Parks, J.K.3
-
90
-
-
79952051533
-
Levodopa in the treatment of Parkinson's disease: An old drug still going strong
-
20852670 1:CAS:528:DC%2BC3cXhtFSmtrrE
-
Poewe W, Antonini A, Zijlmans JC, Burkhard PR, Vingerhoets F (2010) Levodopa in the treatment of Parkinson's disease: an old drug still going strong. Clin Interv Aging 5:229-238
-
(2010)
Clin Interv Aging
, vol.5
, pp. 229-238
-
-
Poewe, W.1
Antonini, A.2
Zijlmans, J.C.3
Burkhard, P.R.4
Vingerhoets, F.5
-
91
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
9197268 1:CAS:528:DyaK2sXkt1altr4%3D 10.1126/science.276.5321.2045
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276:2045-2047
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
92
-
-
0036067526
-
Mitochondrial voltage-dependent anion channel is involved in dopamine-induced apoptosis
-
12124435 1:CAS:528:DC%2BD38XlslKmtrk%3D 10.1046/j.1471-4159.2002.00966.x
-
Premkumar A, Simantov R (2002) Mitochondrial voltage-dependent anion channel is involved in dopamine-induced apoptosis. J Neurochem 82:345-352
-
(2002)
J Neurochem
, vol.82
, pp. 345-352
-
-
Premkumar, A.1
Simantov, R.2
-
93
-
-
26944453586
-
Like cops on the beat: The active role of resting microglia
-
16165228 1:CAS:528:DC%2BD2MXhtFektbvI 10.1016/j.tins.2005.09.001
-
Raivich G (2005) Like cops on the beat: the active role of resting microglia. Trends Neurosci 28:571-573
-
(2005)
Trends Neurosci
, vol.28
, pp. 571-573
-
-
Raivich, G.1
-
94
-
-
84860813005
-
Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: Evidence from observational studies
-
Rees K, Stowe R, Patel S, Ives N, Breen K, Clarke CE, Ben Shlomo Y (2011) Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson's disease: evidence from observational studies. Cochrane Database Syst Rev CD008454
-
(2011)
Cochrane Database Syst Rev
-
-
Rees, K.1
Stowe, R.2
Patel, S.3
Ives, N.4
Breen, K.5
Clarke, C.E.6
Ben Shlomo, Y.7
-
95
-
-
64549093797
-
Circulating interleukin-10 and interleukin-12 in Parkinson's disease
-
18976327 1:CAS:528:DC%2BD1MXmtVSns7w%3D 10.1111/j.1600-0404.2008.01103.x
-
Rentzos M, Nikolaou C, Andreadou E, Paraskevas GP, Rombos A, Zoga M, Tsoutsou A, Boufidou F, Kapaki E, Vassilopoulos D (2009) Circulating interleukin-10 and interleukin-12 in Parkinson's disease. Acta Neurol Scand 119:332-337
-
(2009)
Acta Neurol Scand
, vol.119
, pp. 332-337
-
-
Rentzos, M.1
Nikolaou, C.2
Andreadou, E.3
Paraskevas, G.P.4
Rombos, A.5
Zoga, M.6
Tsoutsou, A.7
Boufidou, F.8
Kapaki, E.9
Vassilopoulos, D.10
-
96
-
-
36249032567
-
Neuroprotective activities of CD4 + CD25+ regulatory T cells in an animal model of Parkinson's disease
-
17675560 1:CAS:528:DC%2BD2sXht1KqsbzI 10.1189/jlb.0507296
-
Reynolds AD, Banerjee R, Liu J, Gendelman HE, Mosley RL (2007) Neuroprotective activities of CD4 + CD25+ regulatory T cells in an animal model of Parkinson's disease. J Leukoc Biol 82:1083-1094
-
(2007)
J Leukoc Biol
, vol.82
, pp. 1083-1094
-
-
Reynolds, A.D.1
Banerjee, R.2
Liu, J.3
Gendelman, H.E.4
Mosley, R.L.5
-
97
-
-
39849085821
-
Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease
-
18036154 1:CAS:528:DC%2BD1cXkt1CitbY%3D 10.1111/j.1471-4159.2007.05087.x
-
Reynolds AD, Glanzer JG, Kadiu I, Ricardo-Dukelow M, Chaudhuri A, Ciborowski P, Cerny R, Gelman B, Thomas MP, Mosley RL, Gendelman HE (2008) Nitrated alpha-synuclein-activated microglial profiling for Parkinson's disease. J Neurochem 104:1504-1525
-
(2008)
J Neurochem
, vol.104
, pp. 1504-1525
-
-
Reynolds, A.D.1
Glanzer, J.G.2
Kadiu, I.3
Ricardo-Dukelow, M.4
Chaudhuri, A.5
Ciborowski, P.6
Cerny, R.7
Gelman, B.8
Thomas, M.P.9
Mosley, R.L.10
Gendelman, H.E.11
-
98
-
-
64249169415
-
Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets
-
19299711 1:CAS:528:DC%2BD1MXjsVSjtLg%3D 10.4049/jimmunol.0803982
-
Reynolds AD, Stone DK, Mosley RL, Gendelman HE (2009) Nitrated {alpha}-synuclein-induced alterations in microglial immunity are regulated by CD4+ T cell subsets. J Immunol 182:4137-4149
-
(2009)
J Immunol
, vol.182
, pp. 4137-4149
-
-
Reynolds, A.D.1
Stone, D.K.2
Mosley, R.L.3
Gendelman, H.E.4
-
99
-
-
0034846276
-
Astroglial and microglial reaction after a partial nigrostriatal degeneration induced by the striatal injection of different doses of 6-hydroxydopamine
-
11699344 1:STN:280:DC%2BD3Mnks1Omtw%3D%3D 10.3109/00207450108986528
-
Rodrigues RW, Gomide VC, Chadi G (2001) Astroglial and microglial reaction after a partial nigrostriatal degeneration induced by the striatal injection of different doses of 6-hydroxydopamine. Int J Neurosci 109:91-126
-
(2001)
Int J Neurosci
, vol.109
, pp. 91-126
-
-
Rodrigues, R.W.1
Gomide, V.C.2
Chadi, G.3
-
100
-
-
0842312949
-
Astroglial and microglial activation in the wistar rat ventral tegmental area after a single striatal injection of 6-hydroxydopamine
-
14702208 1:STN:280:DC%2BD2c%2Fgs1Sgsw%3D%3D 10.1080/00207450490249338
-
Rodrigues RW, Gomide VC, Chadi G (2004) Astroglial and microglial activation in the wistar rat ventral tegmental area after a single striatal injection of 6-hydroxydopamine. Int J Neurosci 114:197-216
-
(2004)
Int J Neurosci
, vol.114
, pp. 197-216
-
-
Rodrigues, R.W.1
Gomide, V.C.2
Chadi, G.3
-
101
-
-
77958575827
-
Risk for Parkinson's disease among patients with osteoarthritis: A Danish cohort study
-
20721917 10.1002/mds.23274
-
Rugbjerg K, Friis S, Jorgensen TL, Ritz B, Korbo L, Olsen JH (2010) Risk for Parkinson's disease among patients with osteoarthritis: a Danish cohort study. Mov Disord 25:2355-2360
-
(2010)
Mov Disord
, vol.25
, pp. 2355-2360
-
-
Rugbjerg, K.1
Friis, S.2
Jorgensen, T.L.3
Ritz, B.4
Korbo, L.5
Olsen, J.H.6
-
102
-
-
69949164871
-
NSAID use and the risk of Parkinson's disease: Systematic review and meta-analysis of observational studies
-
19728750 1:CAS:528:DC%2BD1MXhsVCkt7%2FM 10.2165/11316780-000000000-00000
-
Samii A, Etminan M, Wiens MO, Jafari S (2009) NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies. Drugs Aging 26:769-779
-
(2009)
Drugs Aging
, vol.26
, pp. 769-779
-
-
Samii, A.1
Etminan, M.2
Wiens, M.O.3
Jafari, S.4
-
103
-
-
77649294300
-
Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease
-
20098715 10.1371/journal.pone.0008784 1:CAS:528:DC%2BC3cXht1entb0%3D
-
Sanchez-Guajardo V, Febbraro F, Kirik D, Romero-Ramos M (2010) Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease. PLoS One 5:e8784
-
(2010)
PLoS One
, vol.5
, pp. 8784
-
-
Sanchez-Guajardo, V.1
Febbraro, F.2
Kirik, D.3
Romero-Ramos, M.4
-
104
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
-
19915576 1:CAS:528:DC%2BD1MXhsVWlsb7O 10.1038/ng.485
-
Satake W et al (2009) Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet 41:1303-1307
-
(2009)
Nat Genet
, vol.41
, pp. 1303-1307
-
-
Satake, W.1
-
105
-
-
0025254401
-
Mitochondrial complex i deficiency in Parkinson's disease
-
2154550 1:CAS:528:DyaK3cXhsFKiur4%3D 10.1111/j.1471-4159.1990.tb02325.x
-
Schapira AH, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD (1990) Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem 54:823-827
-
(1990)
J Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
106
-
-
0037402801
-
Selective microglial activation in the rat rotenone model of Parkinson's disease
-
12686372 1:CAS:528:DC%2BD3sXislensrs%3D 10.1016/S0304-3940(03)00172-1
-
Sherer TB, Betarbet R, Kim JH, Greenamyre JT (2003) Selective microglial activation in the rat rotenone model of Parkinson's disease. Neurosci Lett 341:87-90
-
(2003)
Neurosci Lett
, vol.341
, pp. 87-90
-
-
Sherer, T.B.1
Betarbet, R.2
Kim, J.H.3
Greenamyre, J.T.4
-
107
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
19915575 1:CAS:528:DC%2BD1MXhsVWlsbrP 10.1038/ng.487
-
Simon-Sanchez J et al (2009) Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 41:1308-1312
-
(2009)
Nat Genet
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
-
108
-
-
79956321752
-
Genome-wide association study confirms extant PD risk loci among the Dutch
-
21248740 1:CAS:528:DC%2BC3MXmtlegsLw%3D 10.1038/ejhg.2010.254
-
Simon-Sanchez J, van Hilten JJ, van de Warrenburg B, Post B, Berendse HW, Arepalli S, Hernandez DG, de Bie RM, Velseboer D, Scheffer H, Bloem B, van Dijk KD, Rivadeneira F, Hofman A, Uitterlinden AG, Rizzu P, Bochdanovits Z, Singleton AB, Heutink P (2011) Genome-wide association study confirms extant PD risk loci among the Dutch. Eur J Hum Genet 19:655-661
-
(2011)
Eur J Hum Genet
, vol.19
, pp. 655-661
-
-
Simon-Sanchez, J.1
Van Hilten, J.J.2
Van De Warrenburg, B.3
Post, B.4
Berendse, H.W.5
Arepalli, S.6
Hernandez, D.G.7
De Bie, R.M.8
Velseboer, D.9
Scheffer, H.10
Bloem, B.11
Van Dijk, K.D.12
Rivadeneira, F.13
Hofman, A.14
Uitterlinden, A.G.15
Rizzu, P.16
Bochdanovits, Z.17
Singleton, A.B.18
Heutink, P.19
-
109
-
-
0242300619
-
Alpha-synuclein locus triplication causes Parkinson's disease
-
14593171 1:CAS:528:DC%2BD3sXoslehsbc%3D 10.1126/science.1090278
-
Singleton AB et al (2003) Alpha-synuclein locus triplication causes Parkinson's disease. Science 302:841
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
-
110
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
9278044 1:CAS:528:DyaK2sXlslWru7o%3D 10.1038/42166
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M (1997) Alpha-synuclein in Lewy bodies. Nature 388:839-840
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
111
-
-
0032568534
-
Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
9600990 1:CAS:528:DyaK1cXjtlKgtLo%3D 10.1073/pnas.95.11.6469
-
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M (1998) Alpha-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci U S A 95:6469-6473
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
112
-
-
68249145501
-
Innate and adaptive immunity for the pathobiology of Parkinson's disease
-
19243239 1:CAS:528:DC%2BD1MXpvFaru7w%3D 10.1089/ars.2009.2460
-
Stone DK, Reynolds AD, Mosley RL, Gendelman HE (2009) Innate and adaptive immunity for the pathobiology of Parkinson's disease. Antioxid Redox Signal 11:2151-2166
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2151-2166
-
-
Stone, D.K.1
Reynolds, A.D.2
Mosley, R.L.3
Gendelman, H.E.4
-
113
-
-
51449099473
-
Synuclein activates microglia in a model of Parkinson's disease
-
17537546 1:CAS:528:DC%2BD1cXhtFCksLzE 10.1016/j.neurobiolaging.2007.04. 006
-
Su X, Maguire-Zeiss KA, Giuliano R, Prifti L, Venkatesh K, Federoff HJ (2008) Synuclein activates microglia in a model of Parkinson's disease. Neurobiol Aging 29:1690-1701
-
(2008)
Neurobiol Aging
, vol.29
, pp. 1690-1701
-
-
Su, X.1
Maguire-Zeiss, K.A.2
Giuliano, R.3
Prifti, L.4
Venkatesh, K.5
Federoff, H.J.6
-
114
-
-
0037469952
-
Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice
-
12576189 1:CAS:528:DC%2BD3sXovFGnsQ%3D%3D 10.1016/S0006-8993(02)04085-4
-
Sugama S, Yang L, Cho BP, DeGiorgio LA, Lorenzl S, Albers DS, Beal MF, Volpe BT, Joh TH (2003) Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice. Brain Res 964:288-294
-
(2003)
Brain Res
, vol.964
, pp. 288-294
-
-
Sugama, S.1
Yang, L.2
Cho, B.P.3
Degiorgio, L.A.4
Lorenzl, S.5
Albers, D.S.6
Beal, M.F.7
Volpe, B.T.8
Joh, T.H.9
-
115
-
-
0029908226
-
Origin and functional consequences of the complex i defect in Parkinson's disease
-
8871587 1:STN:280:DyaK2s%2FisFeqtQ%3D%3D 10.1002/ana.410400417
-
Swerdlow RH, Parks JK, Miller SW, Tuttle JB, Trimmer PA, Sheehan JP, Bennett JP Jr, Davis RE, Parker WD Jr (1996) Origin and functional consequences of the complex I defect in Parkinson's disease. Ann Neurol 40:663-671
-
(1996)
Ann Neurol
, vol.40
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett Jr., J.P.7
Davis, R.E.8
Parker Jr., W.D.9
-
116
-
-
58149380755
-
Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease
-
19018246 1:CAS:528:DC%2BD1MXkt1Gmuw%3D%3D 10.1097/NEN.0b013e31818e5e99
-
Theodore S, Cao S, McLean PJ, Standaert DG (2008) Targeted overexpression of human alpha-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease. J Neuropathol Exp Neurol 67:1149-1158
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 1149-1158
-
-
Theodore, S.1
Cao, S.2
McLean, P.J.3
Standaert, D.G.4
-
117
-
-
33746894717
-
Nonsteroidal anti-inflammatory drugs and risk of Parkinson's disease
-
Ton TG, Heckbert SR, Longstreth WT, Jr., Rossing MA, Kukull WA, Franklin GM, Swanson PD, Smith-Weller T, Checkoway H (2006) Nonsteroidal anti-inflammatory drugs and risk of Parkinson's disease. Mov Disord
-
(2006)
Mov Disord
-
-
Ton, T.G.1
Heckbert, S.R.2
Longstreth Jr., W.T.3
Ma, R.4
Kukull, W.A.5
Franklin, G.M.6
Swanson, P.D.7
Smith-Weller, T.8
Checkoway, H.9
-
118
-
-
0035816404
-
Pesticides directly accelerate the rate of alpha-synuclein fibril formation: A possible factor in Parkinson's disease
-
11445065 1:CAS:528:DC%2BD3MXkvVelsrg%3D 10.1016/S0014-5793(01)02597-2
-
Uversky VN, Li J, Fink AL (2001) Pesticides directly accelerate the rate of alpha-synuclein fibril formation: a possible factor in Parkinson's disease. FEBS Lett 500:105-108
-
(2001)
FEBS Lett
, vol.500
, pp. 105-108
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
119
-
-
67649760168
-
Mitochondrial dynamics in Parkinson's disease
-
19332061 10.1016/j.expneurol.2009.03.019 1:CAS:528:DC%2BD1MXosVWlt78%3D
-
Van Laar VS, Berman SB (2009) Mitochondrial dynamics in Parkinson's disease. Exp Neurol 218:247-256
-
(2009)
Exp Neurol
, vol.218
, pp. 247-256
-
-
Van Laar, V.S.1
Berman, S.B.2
-
120
-
-
79951502361
-
Clinical subtypes of Parkinson's disease
-
21322019 10.1002/mds.23346
-
van Rooden SM, Colas F, Martinez-Martin P, Visser M, Verbaan D, Marinus J, Chaudhuri RK, Kok JN, van Hilten JJ (2011) Clinical subtypes of Parkinson's disease. Mov Disord 26:51-58
-
(2011)
Mov Disord
, vol.26
, pp. 51-58
-
-
Van Rooden, S.M.1
Colas, F.2
Martinez-Martin, P.3
Visser, M.4
Verbaan, D.5
Marinus, J.6
Chaudhuri, R.K.7
Kok, J.N.8
Van Hilten, J.J.9
-
121
-
-
0030471162
-
TGFbeta1 and TGFbeta2 concentrations are elevated in Parkinson's disease in ventricular cerebrospinal fluid
-
8934562 1:CAS:528:DyaK28Xnt1yju7o%3D 10.1006/exnr.1996.0200
-
Vawter MP, Dillon-Carter O, Tourtellotte WW, Carvey P, Freed WJ (1996) TGFbeta1 and TGFbeta2 concentrations are elevated in Parkinson's disease in ventricular cerebrospinal fluid. Exp Neurol 142:313-322
-
(1996)
Exp Neurol
, vol.142
, pp. 313-322
-
-
Vawter, M.P.1
Dillon-Carter, O.2
Tourtellotte, W.W.3
Carvey, P.4
Freed, W.J.5
-
122
-
-
78149466909
-
Alpha-synuclein and dopamine at the crossroads of Parkinson's disease
-
20961626 1:CAS:528:DC%2BC3cXhsVagurnN 10.1016/j.tins.2010.09.004
-
Venda LL, Cragg SJ, Buchman VL, Wade-Martins R (2010) Alpha-synuclein and dopamine at the crossroads of Parkinson's disease. Trends Neurosci 33:559-568
-
(2010)
Trends Neurosci
, vol.33
, pp. 559-568
-
-
Venda, L.L.1
Cragg, S.J.2
Buchman, V.L.3
Wade-Martins, R.4
-
123
-
-
84869187974
-
Molecular imaging of microglia/macrophages in the brain
-
22615180 10.1002/glia.22357
-
Venneti S, Lopresti BJ, Wiley CA (2013) Molecular imaging of microglia/macrophages in the brain. Glia 61:10-23
-
(2013)
Glia
, vol.61
, pp. 10-23
-
-
Venneti, S.1
Lopresti, B.J.2
Wiley, C.A.3
-
124
-
-
35948985533
-
Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease
-
17984451 1:CAS:528:DC%2BD2sXht1emurrF 10.1212/01.wnl.0000279519.99344.ad
-
Wahner AD, Bronstein JM, Bordelon YM, Ritz B (2007) Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease. Neurology 69:1836-1842
-
(2007)
Neurology
, vol.69
, pp. 1836-1842
-
-
Wahner, A.D.1
Bronstein, J.M.2
Bordelon, Y.M.3
Ritz, B.4
-
125
-
-
0036522967
-
Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
-
11880505 1:CAS:528:DC%2BD38XhvValtbo%3D
-
Wu DC, Jackson-Lewis V, Vila M, Tieu K, Teismann P, Vadseth C, Choi DK, Ischiropoulos H, Przedborski S (2002) Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 22:1763-1771
-
(2002)
J Neurosci
, vol.22
, pp. 1763-1771
-
-
Wu, D.C.1
Jackson-Lewis, V.2
Vila, M.3
Tieu, K.4
Teismann, P.5
Vadseth, C.6
Choi, D.K.7
Ischiropoulos, H.8
Przedborski, S.9
-
126
-
-
84863325404
-
Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease
-
Xie W, Chung KK (2012) Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease. J Neurochem
-
(2012)
J Neurochem
-
-
Xie, W.1
Chung, K.K.2
-
127
-
-
79956124664
-
Autophagic pathways in Parkinson disease and related disorders
-
21418705 10.1017/S1462399411001803 1:CAS:528:DC%2BC3MXksVKjur0%3D
-
Xilouri M, Stefanis L (2011) Autophagic pathways in Parkinson disease and related disorders. Expert Rev Mol Med 13:e8
-
(2011)
Expert Rev Mol Med
, vol.13
, pp. 8
-
-
Xilouri, M.1
Stefanis, L.2
-
128
-
-
0141593395
-
Minocycline enhances MPTP toxicity to dopaminergic neurons
-
14515357 1:CAS:528:DC%2BD3sXotVWgtL4%3D 10.1002/jnr.10709
-
Yang L, Sugama S, Chirichigno JW, Gregorio J, Lorenzl S, Shin DH, Browne SE, Shimizu Y, Joh TH, Beal MF, Albers DS (2003) Minocycline enhances MPTP toxicity to dopaminergic neurons. J Neurosci Res 74:278-285
-
(2003)
J Neurosci Res
, vol.74
, pp. 278-285
-
-
Yang, L.1
Sugama, S.2
Chirichigno, J.W.3
Gregorio, J.4
Lorenzl, S.5
Shin, D.H.6
Browne, S.E.7
Shimizu, Y.8
Joh, T.H.9
Beal, M.F.10
Albers, D.S.11
-
129
-
-
79960826207
-
The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
-
21613270 1:CAS:528:DC%2BC3MXpt1Ohu7w%3D 10.1093/hmg/ddr235
-
Yu W, Sun Y, Guo S, Lu B (2011) The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Hum Mol Genet 20:3227-3240
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3227-3240
-
-
Yu, W.1
Sun, Y.2
Guo, S.3
Lu, B.4
-
130
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
14755719 1:CAS:528:DC%2BD2cXhs1Sgtb0%3D 10.1002/ana.10795
-
Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E, Ros R, Ampuero I, Vidal L, Hoenicka J, Rodriguez O, Atares B, Llorens V, Gomez TE, del Ser T, Munoz DG, de Yebenes JG (2004) The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann Neurol 55:164-173
-
(2004)
Ann Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez, T.E.12
Del Ser, T.13
Munoz, D.G.14
De Yebenes, J.G.15
-
132
-
-
20144389524
-
Aggregated alpha-synuclein activates microglia: A process leading to disease progression in Parkinson's disease
-
15791003 1:CAS:528:DC%2BD2MXjtFaqsrc%3D 10.1096/fj.04-2751com
-
Zhang W, Wang T, Pei Z, Miller DS, Wu X, Block ML, Wilson B, Zhang W, Zhou Y, Hong JS, Zhang J (2005) Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB J 19:533-542
-
(2005)
FASEB J
, vol.19
, pp. 533-542
-
-
Zhang, W.1
Wang, T.2
Pei, Z.3
Miller, D.S.4
Wu, X.5
Block, M.L.6
Wilson, B.7
Zhang, W.8
Zhou, Y.9
Hong, J.S.10
Zhang, J.11
|