Extracellular signal-regulated kinase is involved in alpha-synuclein-induced mitochondrial dynamic disorders by regulating dynamin-like protein 1

Neurobiology of Aging

Volumn 33, Issue 12, 2012, Pages 2841-2854

  Gui, Ya Xing ^a   Wang, Xin Yi ^a   Kang, Wen Yan ^a   Zhang, Ying Jie ^a   Zhang, Yu ^a   Zhou, Yong ^b   Quinn, Thomas J ^c   Liu, Jun ^a   Chen, Sheng Di ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

DLP1; ERK; Mitochondrial dynamic; SNCA

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA SYNUCLEIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; DYNAMIN I; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOUSE; NEUROMODULATION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEOMICS; SIGNAL TRANSDUCTION; VALIDATION PROCESS;

ALPHA-SYNUCLEIN; ANALYSIS OF VARIANCE; ANIMALS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GREEN FLUORESCENT PROTEINS; GTP PHOSPHOHYDROLASES; HUMANS; ISOTOPES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTEINS; MUTATION; NEUROBLASTOMA; NEURONS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TANDEM MASS SPECTROMETRY; TRANSFECTION;

EID: 84866768467     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.02.001     Document Type: Article

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