T cell depletion protects against alveolar destruction due to chronic cigarette smoke exposure in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 304, Issue 5, 2013, Pages

  Podolin, Patricia L ^a   Foley, Joseph P ^a   Carpenter, Donald C ^a   Bolognese, Brian J ^a   Logan, Gregory A ^a   Long III, Edward ^a   Harrison, Oliver J ^a   Walsh, Patrick T ^a,b  

^a GLAXOSMITHKLINE   (United States)

^b OUR LADY S CHILDREN S HOSPITAL   (Ireland)

Author keywords

Chronic obstructive pulmonary disease; Cigarette smoke; T helper 17

Indexed keywords

CASPASE 3; CASPASE 7; CIGARETTE SMOKE; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOSPORIN A; GAMMA INTERFERON; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 2; HEME OXYGENASE 1; INTERLEUKIN 17; MACROPHAGE ELASTASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 2; MANGANESE SUPEROXIDE DISMUTASE; MONOCYTE CHEMOTACTIC PROTEIN 1;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROTECTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; FEMALE; GENE ACTIVITY; GENE EXPRESSION; HELPER CELL; IMMUNE DEFICIENCY; LIPID PEROXIDATION; LUNG ALVEOLUS; LUNG EMPHYSEMA; LYMPHOCYTIC INFILTRATION; MONONUCLEAR CELL; MOUSE; NEUTROPHIL CHEMOTAXIS; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; T CELL DEPLETION; T LYMPHOCYTE SUBPOPULATION; TH17 CELL;

ANIMALS; CASPASE 3; CASPASE 7; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYCLOSPORINE; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; IMMUNOSUPPRESSION; INTERLEUKIN-17; LUNG VOLUME MEASUREMENTS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; TOBACCO SMOKE POLLUTION;

EID: 84874639574     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00152.2012     Document Type: Article

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