Smoking gun: Mature dendritic cells in human lung provide clues to chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 180, Issue 12, 2009, Pages 1166-1167

  Kheradmand, Farrah ^a   Shan, Ming ^a   Corry, David B ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD69 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; CIGARETTE SMOKE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; TOLL LIKE RECEPTOR;

ADAPTIVE IMMUNITY; ANTIGEN PRESENTING CELL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DENDRITIC CELL; EDITORIAL; EMPHYSEMA; ENDOSOME; FLOW CYTOMETRY; HUMAN; IMMUNOCOMPETENT CELL; LUNG PARENCHYMA; LYSOSOME; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; SMOKING; SMOKING CESSATION;

DENDRITIC CELLS; HUMANS; LUNG; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 72549108639     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200909-1391ED     Document Type: Editorial

References (16)

1. Anthonisen NR, Connett JE, Murray RP. Smoking and lung function of Lung Health Study participants after 11 years. Am J Respir Crit Care Med 2002;166:675-679.
2. Hogg JC. Chronic obstructive pulmonary disease: an overview of pathology and pathogenesis. Novartis Found Symp 2001;234:4-19, discussion 19-26.
3. Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med 2009;360:2445-2454.
4. GeurtsvanKessel CH, Lambrecht BN. Division of labor between dendritic cell subsets of the lung. Mucosal Immunol 2008;1:442-450.
5. Mahnke K, Guo M, Lee S, Sepulveda H, Swain SL, Nussenzweig M, Steinman RM. The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments. J Cell Biol 2000;151:673-684.
6. Blanco P, Palucka AK, Pascual V, Banchereau J. Dendritic cells and cytokines in human inflammatory and autoimmune diseases. Cytokine Growth Factor Rev 2008;19:41-52.
7. Ueno H, Klechevsky E, Morita R, Aspord C, Cao T, Matsui T, Di Pucchio T, Connolly J, Fay JW, Pascual V, et al. Dendritic cell subsets in health and disease. Immunol Rev 2007;219:118-142. (Pubitemid 47393528)
8. Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008;8: 193-204. (Pubitemid 351323293)
9. Kool M, van Nimwegen M, Willart MAM, Muskens F, Boon L, Smit JJ, Coyle A, Clausen BE, Hoogsteden HC, Lambrecht BN, et al. An antiinflammatory role for plasmacytoid dendritic cells in allergic airway inflammation. J Immunol 2009;183:1074-1082.
10. Shan M, Han-Fang Cheng HF, Song LZ, Roberts L, Green L, Hacken-Bitar J, Huh J, Bakaeen F, Coxson H, Storness-Bliss C, et al. Lung myeloid dendritic cells coordinately induce Th1 and Th17 responses in human emphysema. Sci Transl Med 2009; (In press).
11. Tsoumakidou M, Zhu J, Wang Z, Thorley A, Kemp S, Tetley T, Jeffery PK. Immunohistochemical detection of dendritic cells in human lung tissue. Histopathology 2007;51:565-568. (Pubitemid 47437838)
12. Demedts IK, Bracke KR, Van Pottelberge G, Testelmans D, Verleden GM, Vermassen FE, Joos GF, Brusselle GG. Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007;175:998-1005. (Pubitemid 46741751)
13. Freeman CM, Martinez FJ, Han MK, Ames TM, Chensue SW, Todt JC, Arenberg DA, Meldrum CA, Getty C, McCloskey M, et al. 2009. Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2009;180:1179-1188.
14. Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE, et al. An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 2004;1:e8.
15. Maeno T, Houghton A, Quintero P, Grumelli S, Owen C, Shapiro S. 2007. CD81 T cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol 2007;178: 8090-8096. (Pubitemid 46898081)
16. Lee SH, Goswami S, Grudo A, Song LZ, Bandi V, Goodnight-White S, Green L, Hacken-Bitar J, Huh J, Bakaeen F, et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nat Med 2007;13:567-569. (Pubitemid 46828488)