-
1
-
-
33645309945
-
-
Bethesda, MD: National Institutes of Health
-
National Heart Lung and Blood Institute, World Health Organization, Global Initiative for Chronic Obstructive Lung Disease. 2004 update: executive summary, global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. Bethesda, MD: National Institutes of Health; 2004.
-
(2004)
2004 Update: Executive Summary, Global Strategy for Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
-
-
-
2
-
-
0029935615
-
Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease
-
Rahman I, MacNee W. Oxidant/antioxidant imbalance in smokers and chronic obstructive pulmonary disease. Thorax 1996;51:348-350.
-
(1996)
Thorax
, vol.51
, pp. 348-350
-
-
Rahman, I.1
MacNee, W.2
-
3
-
-
0027315040
-
New perspectives on basic mechanisms in lung disease. 6. Proteinase imbalance: Its role in lung disease
-
Tetley TD. New perspectives on basic mechanisms in lung disease. 6. Proteinase imbalance: its role in lung disease. Thorax 1993;48:560-565.
-
(1993)
Thorax
, vol.48
, pp. 560-565
-
-
Tetley, T.D.1
-
4
-
-
0029156848
-
Optimal assessment and management of chronic obstructive pulmonary disease (COPD): A consensus statement of the European Respiratory Society
-
Siafakas NM, Vermeire P, Pride NB, Paoletti P, Gibson J, Howard P, Yernault JC, Decramer M, Higenbottam T, Postma DS, et al. Optimal assessment and management of chronic obstructive pulmonary disease (COPD): a consensus statement of the European Respiratory Society. Eur Respir J 1995;8:1398-1420.
-
(1995)
Eur Respir J
, vol.8
, pp. 1398-1420
-
-
Siafakas, N.M.1
Vermeire, P.2
Pride, N.B.3
Paoletti, P.4
Gibson, J.5
Howard, P.6
Yernault, J.C.7
Decramer, M.8
Higenbottam, T.9
Postma, D.S.10
-
5
-
-
9844225600
-
Inflammatory cells in the bronchial glands of smokers with chronic bronchitis
-
Saetta M, Turato G, Facchini FM, Corbino L, Lucchini RE, Casoni G, Maestrelli P, Mapp CE, Ciaccia A, Fabbri LM. Inflammatory cells in the bronchial glands of smokers with chronic bronchitis. Am J Respir Crit Care Med 1997;156:1633-1639.
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 1633-1639
-
-
Saetta, M.1
Turato, G.2
Facchini, F.M.3
Corbino, L.4
Lucchini, R.E.5
Casoni, G.6
Maestrelli, P.7
Mapp, C.E.8
Ciaccia, A.9
Fabbri, L.M.10
-
6
-
-
0030823772
-
Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice
-
Hautamaki RD, Kobayashi DK, Senior RM, Shapiro SD. Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 1997;277:2002-2004.
-
(1997)
Science
, vol.277
, pp. 2002-2004
-
-
Hautamaki, R.D.1
Kobayashi, D.K.2
Senior, R.M.3
Shapiro, S.D.4
-
7
-
-
0032790739
-
Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema
-
Ofulue AF, Ko M. Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema. Am J Physiol 1999;277:L97-L105.
-
(1999)
Am J Physiol
, vol.277
-
-
Ofulue, A.F.1
Ko, M.2
-
8
-
-
0036727064
-
Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice
-
Churg A, Zay K, Shay S, Xie C, Shapiro SD, Hendricks R, Wright JL. Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice. Am J Respir Cell Mol Biol 2002;27:368-374.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 368-374
-
-
Churg, A.1
Zay, K.2
Shay, S.3
Xie, C.4
Shapiro, S.D.5
Hendricks, R.6
Wright, J.L.7
-
9
-
-
0032798485
-
CD8+ cells in the lungs of smokers with chronic obstructive pulmonary disease
-
Saetta M, Baraldo S, Corbino L, Turato G, Braccioni F, Rea F, Cavallesco G, Tropeano G, Mapp CE, Maestrelli P, et al. CD8+ cells in the lungs of smokers with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160:711-717.
-
(1999)
Am J Respir Crit Care Med
, vol.160
, pp. 711-717
-
-
Saetta, M.1
Baraldo, S.2
Corbino, L.3
Turato, G.4
Braccioni, F.5
Rea, F.6
Cavallesco, G.7
Tropeano, G.8
Mapp, C.E.9
Maestrelli, P.10
-
10
-
-
0031035969
-
Peripheral blood lymphocyte cell subsets in subjects with chronic obstructive pulmonary disease: Association with smoking, IgE and lung function
-
de Jong JW, Belt-Gritter B, Koeter GH, Postma DS. Peripheral blood lymphocyte cell subsets in subjects with chronic obstructive pulmonary disease: association with smoking, IgE and lung function. Respir Med 1997;91:67-76.
-
(1997)
Respir Med
, vol.91
, pp. 67-76
-
-
De Jong, J.W.1
Belt-Gritter, B.2
Koeter, G.H.3
Postma, D.S.4
-
11
-
-
0036644755
-
Airway inflammation in severe chronic obstructive pulmonary disease: Relationship with lung function and radiologic emphysema
-
Turato G, Zuin R, Miniati M, Baraldo S, Rea F, Beghe B, Monti S, Formichi B, Boschetto P, Harari S, et al. Airway inflammation in severe chronic obstructive pulmonary disease: relationship with lung function and radiologic emphysema. Am J Respir Crit Care Med 2002;166:105-110.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 105-110
-
-
Turato, G.1
Zuin, R.2
Miniati, M.3
Baraldo, S.4
Rea, F.5
Beghe, B.6
Monti, S.7
Formichi, B.8
Boschetto, P.9
Harari, S.10
-
12
-
-
2942720573
-
The nature of small-airway obstruction in chronic obstructive pulmonary disease
-
Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645-2653.
-
(2004)
N Engl J Med
, vol.350
, pp. 2645-2653
-
-
Hogg, J.C.1
Chu, F.2
Utokaparch, S.3
Woods, R.4
Elliott, W.M.5
Buzatu, L.6
Cherniack, R.M.7
Rogers, R.M.8
Sciurba, F.C.9
Coxson, H.O.10
-
13
-
-
0026591525
-
Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunocytochemistry
-
Bosken CH, Hards J, Gatter K, Hogg JC. Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunocytochemistry. Am Rev Respir Dis 1992;145:911-917.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 911-917
-
-
Bosken, C.H.1
Hards, J.2
Gatter, K.3
Hogg, J.C.4
-
14
-
-
33645306919
-
Inflammatory changes and time course of emphysema induction in smoking C57/Bl6j mice
-
van der Strate BWA, Hylkema MN, Postma DS, Timens W, Kerstjens HAM. Inflammatory changes and time course of emphysema induction in smoking C57/Bl6j mice [abstract]. Eur Respir J 2002;20:485S.
-
(2002)
Eur Respir J
, vol.20
-
-
Van Der Strate, B.W.A.1
Hylkema, M.N.2
Postma, D.S.3
Timens, W.4
Kerstjens, H.A.M.5
-
15
-
-
30744454319
-
Inflammation in cigarette smoke induced emphysema in C57Bl/6 mice
-
van der Strate BW, Postma DS, Luinge M, Geerlings M, Klok PA, Melgert BN, Hylkema MN, Timens W, Kerstjens HA. Inflammation in cigarette smoke induced emphysema in C57Bl/6 mice [abstract]. Am J Respir Crit Care Med 2003;167:A74.
-
(2003)
Am J Respir Crit Care Med
, vol.167
-
-
Van Der Strate, B.W.1
Postma, D.S.2
Luinge, M.3
Geerlings, M.4
Klok, P.A.5
Melgert, B.N.6
Hylkema, M.N.7
Timens, W.8
Kerstjens, H.A.9
-
16
-
-
0032842109
-
Proteoglycan changes in the extracellular matrix of lung tissue from patients with pulmonary emphysema
-
van Straaten JF, Coers W, Noordhoek JA, Huitema S, Flipsen JT, Kauffman HF, Timens W, Postma DS. Proteoglycan changes in the extracellular matrix of lung tissue from patients with pulmonary emphysema. Mod Pathol 1999;12:697-705.
-
(1999)
Mod Pathol
, vol.12
, pp. 697-705
-
-
Van Straaten, J.F.1
Coers, W.2
Noordhoek, J.A.3
Huitema, S.4
Flipsen, J.T.5
Kauffman, H.F.6
Timens, W.7
Postma, D.S.8
-
17
-
-
0035479946
-
TP53 gene mutations in Hodgkin lymphoma are infrequent and not associated with absence of Epstein-Barr virus
-
Maggio EM, Stekelenburg E, Van den BA, Poppema S. TP53 gene mutations in Hodgkin lymphoma are infrequent and not associated with absence of Epstein-Barr virus. Int J Cancer 2001;94:60-66.
-
(2001)
Int J Cancer
, vol.94
, pp. 60-66
-
-
Maggio, E.M.1
Stekelenburg, E.2
Van Den, B.A.3
Poppema, S.4
-
18
-
-
0021965821
-
Simultaneous mainstream-sidestream smoke exposure systems. I. Equipment and procedures
-
Griffith RB, Hancock R. Simultaneous mainstream-sidestream smoke exposure systems. I. Equipment and procedures. Toxicology 1985;34:123-138.
-
(1985)
Toxicology
, vol.34
, pp. 123-138
-
-
Griffith, R.B.1
Hancock, R.2
-
19
-
-
0021991242
-
Simultaneous mainstream-sidestream smoke exposure systems. II. The rat exposure system
-
Griffith RB, Standafer S. Simultaneous mainstream-sidestream smoke exposure systems. II. The rat exposure system. Toxicology 1985;35:13-24.
-
(1985)
Toxicology
, vol.35
, pp. 13-24
-
-
Griffith, R.B.1
Standafer, S.2
-
20
-
-
0014089071
-
Measurement of pulmonary emphysema
-
Thurlbeck WM. Measurement of pulmonary emphysema. Am Rev Respir Dis 1967;95:752-764.
-
(1967)
Am Rev Respir Dis
, vol.95
, pp. 752-764
-
-
Thurlbeck, W.M.1
-
21
-
-
0035671548
-
Naive and memory B cells in T-cell-dependent and T-independent responses
-
Zubler RH. Naive and memory B cells in T-cell-dependent and T-independent responses. Springer Semin Immunopathol 2001;23:405-419.
-
(2001)
Springer Semin Immunopathol
, vol.23
, pp. 405-419
-
-
Zubler, R.H.1
-
22
-
-
0025686321
-
Germinal center reaction and B lymphocytes: Morphology and function
-
Kroese FG, Timens W, Nieuwenhuis P. Germinal center reaction and B lymphocytes: morphology and function. Curr Top Pathol 1990;84:103-148.
-
(1990)
Curr Top Pathol
, vol.84
, pp. 103-148
-
-
Kroese, F.G.1
Timens, W.2
Nieuwenhuis, P.3
-
24
-
-
0037649055
-
Sustained interleukin-6 signalling leads to the development of lymphoid organ-like structures in the lung
-
Goya S, Matsuoka H, Mori M, Morishita H, Kida H, Kobashi Y, Kato T, Taguchi Y, Osaki T, Tachibana I, et al. Sustained interleukin-6 signalling leads to the development of lymphoid organ-like structures in the lung. J Pathol 2003;200:82-87.
-
(2003)
J Pathol
, vol.200
, pp. 82-87
-
-
Goya, S.1
Matsuoka, H.2
Mori, M.3
Morishita, H.4
Kida, H.5
Kobashi, Y.6
Kato, T.7
Taguchi, Y.8
Osaki, T.9
Tachibana, I.10
-
25
-
-
0033761127
-
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema
-
Zheng T, Zhu Z, Wang Z, Homer RJ, Ma B, Riese RJ Jr, Chapman HA Jr, Shapiro SD, Elias JA. Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema. J Clin Invest 2000;106:1081-1093.
-
(2000)
J Clin Invest
, vol.106
, pp. 1081-1093
-
-
Zheng, T.1
Zhu, Z.2
Wang, Z.3
Homer, R.J.4
Ma, B.5
Riese Jr., R.J.6
Chapman Jr., H.A.7
Shapiro, S.D.8
Elias, J.A.9
-
26
-
-
0036727140
-
Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations
-
Patel IS, Seemungal TA, Wilks M, Lloyd-Owen SJ, Donaldson GC, Wedzicha JA. Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations. Thorax 2002;57:759-764.
-
(2002)
Thorax
, vol.57
, pp. 759-764
-
-
Patel, I.S.1
Seemungal, T.A.2
Wilks, M.3
Lloyd-Owen, S.J.4
Donaldson, G.C.5
Wedzicha, J.A.6
-
27
-
-
0035421665
-
Amplification of inflammation in emphysema and its association with latent adenoviral infection
-
Retamales I, Elliott WM, Meshi B, Coxson HO, Pare PD, Sciurba FC, Rogers RM, Hayashi S, Hogg JC. Amplification of inflammation in emphysema and its association with latent adenoviral infection. Am J Respir Crit Care Med 2001;164:469-473.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 469-473
-
-
Retamales, I.1
Elliott, W.M.2
Meshi, B.3
Coxson, H.O.4
Pare, P.D.5
Sciurba, F.C.6
Rogers, R.M.7
Hayashi, S.8
Hogg, J.C.9
-
28
-
-
0036006795
-
Emphysematous lung destruction by cigarette smoke: The effects of latent adenoviral infection on the lung inflammatory response
-
Meshi B, Vitalis TZ, Ionescu D, Elliott WM, Liu C, Wang XD, Hayashi S, Hogg JC. Emphysematous lung destruction by cigarette smoke: the effects of latent adenoviral infection on the lung inflammatory response. Am J Respir Cell Mol Biol 2002;26:52-57.
-
(2002)
Am J Respir Cell Mol Biol
, vol.26
, pp. 52-57
-
-
Meshi, B.1
Vitalis, T.Z.2
Ionescu, D.3
Elliott, W.M.4
Liu, C.5
Wang, X.D.6
Hayashi, S.7
Hogg, J.C.8
-
29
-
-
0029584854
-
Virus-specific, antibody-secreting cells during upper respiratory infections
-
Makela MJ, Nikkari S, Meurman O, Laine M, Arvilommi H. Virus-specific, antibody-secreting cells during upper respiratory infections. J Med Virol 1995;47:416-420.
-
(1995)
J Med Virol
, vol.47
, pp. 416-420
-
-
Makela, M.J.1
Nikkari, S.2
Meurman, O.3
Laine, M.4
Arvilommi, H.5
-
30
-
-
4344675455
-
Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
-
Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 2004;364:709-721.
-
(2004)
Lancet
, vol.364
, pp. 709-721
-
-
Hogg, J.C.1
-
31
-
-
0036580648
-
Effects of cigarette smoke on the immune system
-
Sopori M. Effects of cigarette smoke on the immune system. Nat Rev Immunol 2002;2:372-377.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 372-377
-
-
Sopori, M.1
-
32
-
-
0017714431
-
Activation of factor XII by tobacco glycoprotein
-
Becker CG, Dubin T. Activation of factor XII by tobacco glycoprotein. J Exp Med 1977;146:457-467.
-
(1977)
J Exp Med
, vol.146
, pp. 457-467
-
-
Becker, C.G.1
Dubin, T.2
-
33
-
-
0036949669
-
Smoking-related DNA and protein adducts in human tissues
-
Phillips DH. Smoking-related DNA and protein adducts in human tissues. Carcinogenesis 2002;23:1979-2004.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1979-2004
-
-
Phillips, D.H.1
-
34
-
-
0033120055
-
Induction and regulation of macrophage metalloelastase by hyaluronan fragments in mouse macrophages
-
Horton MR, Shapiro S, Bao C, Lowenstein CJ, Noble PW. Induction and regulation of macrophage metalloelastase by hyaluronan fragments in mouse macrophages. J Immunol 1999;162:4171-4176.
-
(1999)
J Immunol
, vol.162
, pp. 4171-4176
-
-
Horton, M.R.1
Shapiro, S.2
Bao, C.3
Lowenstein, C.J.4
Noble, P.W.5
-
35
-
-
0029808003
-
Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages: The role of HA size and CD44
-
McKee CM, Penno MB, Cowman M, Burdick MD, Strieter RM, Bao C, Noble PW. Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages: the role of HA size and CD44. J Clin Invest 1996;98:2403-2413.
-
(1996)
J Clin Invest
, vol.98
, pp. 2403-2413
-
-
McKee, C.M.1
Penno, M.B.2
Cowman, M.3
Burdick, M.D.4
Strieter, R.M.5
Bao, C.6
Noble, P.W.7
-
36
-
-
0030989022
-
Hyaluronate-CD44 interactions can induce murine B-cell activation
-
Rafi A, Nagarkatti M, Nagarkatti PS. Hyaluronate-CD44 interactions can induce murine B-cell activation. Blood 1997;89:2901-2908.
-
(1997)
Blood
, vol.89
, pp. 2901-2908
-
-
Rafi, A.1
Nagarkatti, M.2
Nagarkatti, P.S.3
-
37
-
-
0037213692
-
Evolutionary clues to the functions of the Toll-like family as surveillance receptors
-
Johnson GB, Brunn GJ, Tang AH, Platt JL. Evolutionary clues to the functions of the Toll-like family as surveillance receptors. Trends Immunol 2003;24:19-24.
-
(2003)
Trends Immunol
, vol.24
, pp. 19-24
-
-
Johnson, G.B.1
Brunn, G.J.2
Tang, A.H.3
Platt, J.L.4
-
38
-
-
0036446020
-
Morphological and molecular pathology of the B cell response in synovitis of rheumatoid arthritis
-
Magalhaes R, Stiehl P, Morawietz L, Berek C, Krenn V. Morphological and molecular pathology of the B cell response in synovitis of rheumatoid arthritis. Virchows Arch 2002;441:415-427.
-
(2002)
Virchows Arch
, vol.441
, pp. 415-427
-
-
Magalhaes, R.1
Stiehl, P.2
Morawietz, L.3
Berek, C.4
Krenn, V.5
-
39
-
-
0034468043
-
Interferon-γ production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*) 0401 and HLADQ8
-
Berg L, Ronnelid J, Sanjeevi CB, Lampa J, Klareskog L. Interferon-γ production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*)0401 and HLADQ8. Arthritis Res 2000;2:75-84.
-
(2000)
Arthritis Res
, vol.2
, pp. 75-84
-
-
Berg, L.1
Ronnelid, J.2
Sanjeevi, C.B.3
Lampa, J.4
Klareskog, L.5
-
40
-
-
0035869603
-
Human monoclonal rheumatoid synovial B lymphocyte hybridoma with a new disease-related specificity for cartilage oligomeric matrix protein
-
Souto-Carneiro MM, Burkhardt H, Muller EC, Hermann R, Otto A, Kraetsch HG, Sack U, Konig A, Heinegard D, Muller-Hermelink HK, et al. Human monoclonal rheumatoid synovial B lymphocyte hybridoma with a new disease-related specificity for cartilage oligomeric matrix protein. J Immunol 2001;166:4202-4208.
-
(2001)
J Immunol
, vol.166
, pp. 4202-4208
-
-
Souto-Carneiro, M.M.1
Burkhardt, H.2
Muller, E.C.3
Hermann, R.4
Otto, A.5
Kraetsch, H.G.6
Sack, U.7
Konig, A.8
Heinegard, D.9
Muller-Hermelink, H.K.10
-
42
-
-
0034018232
-
Ongoing airway inflammation in patients with COPD who do not currently smoke
-
Rutgers SR, Postma DS, ten Hacken NH, Kauffman HF, van Der Mark TW, Koëter GH, Timens W. Ongoing airway inflammation in patients with COPD who do not currently smoke. Thorax 2000;55:12-18.
-
(2000)
Thorax
, vol.55
, pp. 12-18
-
-
Rutgers, S.R.1
Postma, D.S.2
Ten Hacken, N.H.3
Kauffman, H.F.4
Van Der Mark, T.W.5
Koëter, G.H.6
Timens, W.7
-
43
-
-
0034949094
-
Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema
-
Majo J, Ghezzo H, Cosio MG. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. Eur Respir J 2001;17:946-953.
-
(2001)
Eur Respir J
, vol.17
, pp. 946-953
-
-
Majo, J.1
Ghezzo, H.2
Cosio, M.G.3
-
44
-
-
0141887302
-
Hypothesis: Does COPD have an autoimmune component?
-
Agusti A, MacNee W, Donaldson K, Cosio M. Hypothesis: does COPD have an autoimmune component? Thorax 2003;58:832-834.
-
(2003)
Thorax
, vol.58
, pp. 832-834
-
-
Agusti, A.1
MacNee, W.2
Donaldson, K.3
Cosio, M.4
|