Caspase-2 and JNK activated by saturated fatty acids are not involved in apoptosis induction but modulate ER stress in human pancreatic β-cells

Cellular Physiology and Biochemistry

Volumn 31, Issue 2-3, 2013, Pages 277-289

  Nemcova Furstova, Vlasta ^a   Balušíková, Kamila ^a   Šrámek, Jan ^a   James, Roger F ^b   Kovář, Jan ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Apoptosis; Caspase 2; Endoplasmic reticulum stress; JNK; Saturated fatty acids; cells

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 2; CASPASE 7; CASPASE 8; CASPASE 9; GLYCOSYLTRANSFERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PROTEIN C JUN; PROTEIN IRE1; SATURATED FATTY ACID; STEARIC ACID; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CELL VIABILITY; CONFOCAL MICROSCOPY; CULTURE MEDIUM; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; NON INSULIN DEPENDENT DIABETES MELLITUS; RNA SPLICING; WESTERN BLOTTING;

EID: 84874596974     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000343367     Document Type: Article

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