Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1

Journal of Biological Chemistry

Volumn 271, Issue 39, 1996, Pages 23914-23919

  Wu, Defeng ^a   Cederbaum, Arthur I ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; ACETYLCYSTEINE; ALCOHOL; ALLYL SULFIDE; ALPHA TOCOPHEROL; ANTIOXIDANT; CARBON TETRACHLORIDE; CATALASE; COMPLEMENTARY DNA; CYTOCHROME P450; DEFEROXAMINE; DIMETHYLNITROSAMINE; ENZYME INHIBITOR; FORMAZAN; ISONIAZID; LACTATE DEHYDROGENASE; N TERT BUTYL ALPHA PHENYLNITRONE; PHORBOL 13 ACETATE 12 MYRISTATE; SUPEROXIDE DISMUTASE; THIOUREA; TROLOX C; TRYPAN BLUE; URIC ACID;

ALCOHOL METABOLISM; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; HEPATOMA CELL; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER TOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL;

ALLYL COMPOUNDS; CELL LINE; CYTOCHROME P-450 CYP2E1; ENZYME INDUCTION; ETHANOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; PYRAZOLES; RECOMBINANT PROTEINS; SULFIDES; TETRADECANOYLPHORBOL ACETATE; THIOUREA; TIME FACTORS; TRANSFECTION; URIC ACID;

EID: 0029816454     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.39.23914     Document Type: Article

References (57)

1. Guengerich, F. P., Kim, D. H., and Iwasaki, M. (1991) Chem. Res. Toxicol. 4, 168-179
2. Koop, D. R. (1992) FASEB J. 6, 724-730
3. Yang, C. S., Patten, C. J., Ishizaki, H., and Yoo, J. S. H. (1991) Methods Enzymol. 206, 595-603
4. Gorsky, L. D., Koop, D. R., and Coon, M. J. (1984) J. Biol. Chem. 259, 6812-6817
5. Ekstrom, G., and Ingelman-Sundberg, MX1989) Biochem. Pharmacol. 38, 1313-1319
6. Cederbaum, A. I. (1989) Free Radical Biol. Med. 7, 559-567
7. Dicker, E., and Cederbaum, A. I. (1988) FASEB J. 2, 2901-2906
8. Puntarulo, S., and Cederbaum, A. I. (1988) Arch. Biochem. Biophys. 266, 435-445
9. Rashba-Step, J., Turro, N. G., and Cederbaum, A. I. (1993) Arch. Biochem. Biophys. 300, 401-408
10. Kukielka, E., and Cederbaum, A. I. (1994) Biochem J. 302, 773-779
11. Albano, E., Tomasi, A., Goria-Gatti, L., Poli, G., Vannini, V., and Dianzani, M. U. (1987) Free Radical Res. Commun. 3, 243-249
12. Reinke, L. A., Lai, E. K., DuBose, C. M., and McCay, P. B. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 9223-9227
13. Albano, E., Tomasi, A., Persson, J.-O., Terelius, Y., Goria-Gatti, L., Ingelman-Sundberg, M., and Dianzani, M. U. (1991) Biochem. Pharmacol. 41, 1895-1902
14. Dianzani, M. U. (1985) Alcohol Alcohol. 20, 161-173
15. Cederbaum, A. I. (1989) Free Radical Biol. Med. 7, 537-539
16. Nordmann, R., Ribiere, C., and Rouach, H. (1992) Free Radical Biol. Med. 12, 219-240
17. Tsukamoto, H. and French, S. W. (1993) Alcohol 10, 439-441
18. French, S. W. (1992) Crit. Rev. Clin. Lab. Sci. 29, 83-115
19. French, S. W., Wong, K., Jui, L., Albano, E., Hagbjork, A. L., and IngelmanSundberg, M. (1993) Exp. Mol. Pathol. 58, 61-75
20. Nanji, A., and French, S. W. (1989) Life Sci. 44, 223-227
21. Castillo, T., Koop, D. R., Kamimura, S., Triadafilopoulos, G., and Tsukamoto, H. (1992) Hepatology 16, 992-996
22. Takahashi, H., Johansson, H., French, S. W., and Ingelman-Sundberg, M. (1992) Pharmacol. Toxicol. 70, 347-352
23. Tsukamoto, H., Towner, S. J., Ciofalo, L. M., and French, S. W. (1986) Hepatology 6, 814-822
24. Nanji, A. A., Zhao, S., Lamb, R. G., Sadrzadeh, S. M. H., Dannenberg, A. J., and Waxman, D. J. (1993) Alcohol. Clin. Exp. Res. 17, 598-603
25. Sadrzadeh, S. M. H., Nanji, A. A., and Price, P. L. (1994) J. Pharmacol. Exp. Ther. 269, 632-636
26. Tsukamoto, H., Home, W., Kamimura, S., Niemela, O., Parkkila, S., YlaHerttuala, S., and Brittenham, G. M. (1995) J. Clin. Invest. 96, 620-630
27. Morimoto, M., Hagbjork, A. L., Nanji, A. A., Ingelman-Sundberg, M., Lindros, K. O., Fu, P. C., Albano, E., and French, S. W. (1993) Alcohol 10, 459-464
28. Dai, Y., Rashba-Step, J., and Cederbaum, A. I. (1993) Biochemistry 32, 6928-6937
29. Dai. Y., and Cederbaum, A. I. (1995) J. Pharmacol. Exp. Ther. 273, 1497-1505
30. Mosmann, T. R. (1983) J. Immunol. Methods 65, 55-63
31. Carmichael, J., DeGraff, W. G., Gazdar, A. F., Minna, J. D., and Mitchell, J. B. (1987) Cancer Res. 47, 936-942
32. Dai, Y., and Cederbaum, A. I. (1995) J. Pharmacol. Exp. Ther. 275, 1614-1622
33. Feierman, D. E., and Cederbaum, A. I. (1986) Biochem. J. 239, 671-677
34. Feierman, D. E., and Cederbaum, A. I. (1985) Alcohol. Clin. Exp. Res. 9, 421-428
35. Brady, J. F., Ishizaki, H., Fukuto, J. H., Lin, M. C., Fadel, A., Gapec, J. M., and Yang, C. S. (1991) Chem. Res. Toxicol. 4, 642-647
36. Malorni, W., Rivabene, R., and Matarrese, P.(1995) Chem. Biol. Interact. 96, 113-123
37. Paracchini, L., Jotti, A., Bottiroli, G., Prosperi, E., Supino, R., and Piccinini., F. (1993) Anticancer Res. 13, 1607-1612
38. Gergel, D., Misik, V., Ondrias, K., and Cederbaum, A. I. (1995) J. Biol. Chem. 270, 20922-20929
39. Aden, D. P., Fogel, A., Plotkin, S., Damjanov, I., and Knowles, B. B. (1979) Nature 282, 615-616
40. Javitt, N. B. (1990) FASEB J. 4, 161-168
41. Sassa, G., Sugita, O., Galbraith, R. A., and Kappas, A. (1987) Biochem. Biophys. Res. Commun. 143, 52-57
42. Waxman, D. J., Lapenson, D. P., Aoyama, T., Gelboin, H. V., Gonzalez, F. J., and Korzekwa, K. (1991) Arch. Biochem. Biophys. 290, 160-166
43. Patten, C. J., Ishizaki, H., Aoyama, T., Lee, M., Ning, S. M., Huang, W., Gonzalez, F. J., and Yang, C. S. (1992) Arch. Biochem. Biophys. 299, 163-171
44. Aoyama, T., Korzekwa, K., Nagata, K., Gillette, J., Gelboin, H. V., and Gonzalez, F. J. (1990) Endocrinology 126, 3101-3106
45. Koop, D. R., Morgan, E. T., Tarr, G. E., and Coon, M. J. (1982) J. Biol. Chem. 257, 8472-8480
46. McMartin, K E., Hedstrom, K. G., Tolf, B. R., Ostling-Wintzell, H., and Blomstrand, R. (1980) Arch. Biochem. Biophys. 199, 606-614
47. Clay, K L., and Murphy, R. C. (1977) Toxicol. Appl. Pharmacol. 39, 39-49
48. Palakodety, R. B., Clejan, L. A., Krikun, G., Feierman, D. E., and Cederbaum, A. I. (1988) J. Biol. Chem. 263, 878-884
49. Magnusson, G., Nyberg, J.-A., Bodin, N.-O., and Hansson, E. (1972) Experientia 28, 1198-1200
50. Carroccio, A., Wu, D., and Cederbaum, A. I. (1994) Biochem. Biophys. Res. Commun. 203, 727-733
51. Knecht, K. T., Thurman, R. G., and Mason, R. P. (1993) Arch. Biochem. Biophys. 303, 339-348
52. Reinke, L. A., Moore, D. R., Hague, C. M., and McCay, P. B. (1994) Free Radical Res. 21, 213-222
53. Kyle, M. E., Miccadei, S., Nakae, D., and Farber, J. L. (1987) Biochem. Biophys. Res. Commun. 149, 889-896
54. Kyle, M. E., Nakae, D., Sakaida, L., Miccadei, S., and Farber, J. L. (1988) J. Biol. Chem. 263, 3784-3789
55. Niemela, O., Parkkila, S., Yla-Herttuala, S., Villanueva, J., Ruebner, B., and Halsted, C. H. (1995) Hepatology 22, 1208-1214
56. Neuman, M. G., Koren, G., and Tiribelli, C. (1993) Biochem. Biophys. Res. Commun. 197, 932-941
57. Neuman, M. G., Cameron, R. G., Shear, N. H., Bellentani, S., and Tiribelli, C. (1995) Gastroenterolosy 109, 555-563