Early alcoholic liver injury: Formation of protein adducts with acetaldehyde and lipid peroxidation products, and expression of CYP2E1 and CYP3A

Alcoholism: Clinical and Experimental Research

Volumn 22, Issue 9, 1998, Pages 2118-2124

  Niemelä, Onni ^b   Parkkila, Seppo ^c   Pasanen, Markku ^c   Iimuro, Yuji ^a   Bradford, Blair ^a   Thurman, Ronald G ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b EP Central Hospital Laboratory   (Finland)

^c NONE

Author keywords

Ethanol Metabolism; Lipid Peroxidation; Liver Disease

Indexed keywords

4 HYDROXYNONENAL; ACETALDEHYDE; ALCOHOL; AMINOTRANSFERASE; CYTOCHROME P450 ISOENZYME; DIMETHYLNITROSAMINE DEMETHYLASE; MALONALDEHYDE;

ALCOHOL LIVER CIRRHOSIS; ALCOHOL METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; ENZYME LOCALIZATION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LIPID DIET; LIPID PEROXIDATION; LIVER FIBROSIS; LIVER NECROSIS; MALE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STAINING; STEATOSIS;

ACETALDEHYDE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; ETHANOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIPID PEROXIDATION; LIVER; LIVER DISEASES, ALCOHOLIC; MALE; MALONDIALDEHYDE; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0032407770     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000374-199812000-00032     Document Type: Article

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