Relationship between oxidative stress and hepatic glutathione levels in ethanol-mediated apoptosis of polarized hepatic cells

World Journal of Gastroenterology

Volumn 15, Issue 21, 2009, Pages 2609-2616

  McVicker, Benita L ^a   Tuma, Pamela L ^b   Kharbanda, Kusum K ^a   Lee, Serene M L ^c   Tuma, Dean J ^a  

^a VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^b CATHOLIC UNIVERSITY OF AMERICA   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Alcohol; Caspase; Fas CD95; Glutathione; WIF B cells

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; BUTHIONINE SULFOXIMINE; CASPASE 3; CASPASE 8; CYTOCHROME P450 2E1; FAS ANTIGEN; GLUTATHIONE; PYRAZOLE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL DAMAGE; CELL DEATH; CELL METABOLISM; CELL POLARITY; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 67651166871     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.15.2609     Document Type: Article

References (16)

1. Natori S, Rust C, Stadheim LM, Srinivasan A, Burgart LJ, Gores GJ. Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis. J Hepatol 2001; 34: 248-253
2. Ihrke G, Neufeld EB, Meads T, Shanks MR, Cassio D, Laurent M, Schroer TA, Pagano RE, Hubbard AL. WIF-B cells: an in vitro model for studies of hepatocyte polarity. J Cell Biol 1993; 123: 1761-1775
3. Bender V, Bravo P, Decaens C, Cassio D. The structural and functional polarity of the hepatic human/rat hybrid WIF-B is a stable and dominant trait. Hepatology 1999; 30: 1002-1010
4. Schaffert CS, Todero SL, McVicker BL, Tuma PL, Sorrell MF, Tuma DJ. WIF-B cells as a model for alcohol-induced hepatocyte injury. Biochem Pharmacol 2004; 67: 2167-2174
5. McVicker BL, Tuma DJ, Kubik JL, Tuma PL, Casey CA. Ethanol-induced apoptosis in polarized hepatic cells possibly through regulation of the Fas pathway. Alcohol Clin Exp Res 2006; 30: 1906-1915
6. Diehl AM. Cytokine regulation of liver injury and repair. Immunol Rev 2000; 174: 160-171
7. Wu D, Cederbaum AI. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicol Appl Pharmacol 2005; 207: 70-76
8. Garcia-Ruiz C, Fernandez-Checa JC. Mitochondrial glutathione: hepatocellular survival-death switch. J Gastroenterol Hepatol 2006; 21 Suppl 3: S3-S6
9. Oh SI, Kim CI, Chun HJ, Park SC. Chronic ethanol consumption affects glutathione status in rat liver. J Nutr 1998; 128: 758-763
10. Rouach H, Fataccioli V, Gentil M, French SW, Morimoto M, Nordmann R. Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology. Hepatology 1997; 25: 351-355
11. Shaw S, Jayatilleke E, Ross WA, Gordon ER, Leiber CS. Ethanol-induced lipid peroxidation: potentiation by long-term alcohol feeding and attenuation by methionine. J Lab Clin Med 1981; 98: 417-424
12. Hentze H, Latta M, Kunstle G, Lucas R, Wendel A. Redox control of hepatic cell death. Toxicol Lett 2003; 139: 111-118
13. Reinke LA, Moyer MJ. p-Nitrophenol hydroxylation. A microsomal oxidation which is highly inducible by ethanol. Drug Metab Dispos 1985; 13: 548-552
14. McVicker BL, Tuma DJ, Kubik JA, Hindemith AM, Baldwin CR, Casey CA. The effect of ethanol on asialoglycoprotein receptor-mediated phagocytosis of apoptotic cells by rat hepatocytes. Hepatology 2002; 36: 1478-1487
15. Hentze H, Kunstle G, Volbracht C, Ertel W, Wendel A. CD95-Mediated murine hepatic apoptosis requires an intact glutathione status. Hepatology 1999; 30: 177-185
16. Haouzi D, Lekehal M, Tinel M, Vadrot N, Caussanel L, Letteron P, Moreau A, Feldmann G, Fau D, Pessayre D. Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice. Hepatology 2001; 33: 1181-1188