Protein adduct species in muscle and liver of rats following acute ethanol administration

Alcohol and Alcoholism

Volumn 40, Issue 6, 2005, Pages 485-493

  Patel, Vinood B ^a   Worall, Simon ^b   Emery, Peter W ^c   Preedy, Victor R ^c  

^a UNIVERSITY OF WESTMINSTER   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; COLLAGEN TYPE 1; COLLAGEN TYPE 2; CYANAMIDE; MALONALDEHYDE; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; SODIUM CHLORIDE;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; LIVER; MALE; MUSCLE DISEASE; NONHUMAN; PLANTARIS MUSCLE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN VARIANT; RAT; SOLEUS MUSCLE; TISSUE HOMOGENATE;

ACETALDEHYDE; ALCOHOLIC INTOXICATION; ALDEHYDE DEHYDROGENASE; ANIMALS; CYANAMIDE; ENZYME-LINKED IMMUNOSORBENT ASSAY; ETHANOL; LIVER; LIVER DISEASES, ALCOHOLIC; MALONDIALDEHYDE; MUSCLE FIBERS, FAST-TWITCH; MUSCLE FIBERS, SLOW-TWITCH; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR ATROPHY; OXIDATION-REDUCTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, WISTAR;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 27744600737     PISSN: 07350414     EISSN: 14643502     Source Type: Journal    
DOI: 10.1093/alcalc/agh196     Document Type: Article

References (46)

1. Adachi, J., Asano, M., Ueno, Y. et al. (2000) 7alpha- and 7beta-hydroperoxycholest-5-en-3beta-ol in muscle as indices of oxidative stress: Response to ethanol dosage in rats. Alcoholism: Clinical and Experimental Research 24, 675-681.
2. Adachi, J., Asano, M., Ueno, Y. et al. (2001) Acute effect of ethanol on 7-hydroperoxycholesterol in muscle and liver. Lipids 36, 267-271.
3. Altomare, E., Grattagliano, I., Vendemiale, G. et al. (1996) Acute ethanol administration induces oxidative changes in rat pancreatic tissue. Gut 38, 742-746.
4. Ardawi, M. S., Majzoub, M. F., Masoud, I. M. et al. (1989) Enzymic and metabolic adaptations in the gastrocnemius, plantaris and soleus muscles of hypocaloric rats. Biochemical Journal 261, 219-225.
5. Bigard, A. X., Sanchez, H., Birot, O. et al. (2000) Myosin heavy chain composition of skeletal muscles in young rats growing under hypobaric hypoxia conditions. Journal of Applied Physiology 88, 479-486.
6. Chen, J., Petersen, D. R., Schenker, S. et al. (2000) Formation of malondialdehyde adducts in livers of rats exposed to ethanol: Role in ethanol-mediated inhibition of cytochrome c oxidase. Alcoholism: Clinical and Experimental Research 24, 544-552.
7. Esterbauer, H., Schaur, R. J. and Zollner, H. (1991) Chemistry and Biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radical Biology and Medicine 11, 81-128.
8. Estruch, R., Nicolas, J. M., Villegas, E. et al. (1993) Relationship between ethanol-related diseases and nutritional status in chronically alcoholic men. Alcohol and Alcoholism 28, 543-550.
9. Fernandez-Sola, J., Sacanella, E., Estruch, R. et al. (1995) Significance of type, II fiber atrophy in chronic alcoholic myopathy. Journal of the, Neurological Sciences 130, 69-76.
10. Hildebrandt, A. L. and Neufer, P. D. (2000) Exercise attenuates the fasting-induced transcriptional activation of metabolic genes in skeletal muscle. American Journal of Physiology, Endocrinology and Metabolism 278, E1078-E1086.
11. Hillbom, M. E., Sarviharju, M. S. and Lindros, K. O. (1983) Potentiation of ethanol toxicity by cyanamide in relation to acetaldehyde accumulation. Toxicology and Applied Pharmacology 70, 133-139.
12. Iimuro, Y., Bradford, B. U., Gao, W. et al. (1996) Detection of alpha-hydroxyethyl free radical adducts in the pancreas after chronic exposure to alcohol in the rat. Molecular Pharmacology 50, 656-661.
13. Kato, S., Kawase, T., Alderman, J. et al. (1990) Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. Gastroenterology 98, 203-210.
14. Kera, Y., Ohbora, Y. and Komura, S. (1988) The metabolism of acetaldehyde and not acetaldehyde itself is responsible for in vivo ethanol-induced lipid peroxidation in rats. Biochemical Pharmacology 37, 3633-3638.
15. Klassen, L. W., Jones, B. L., Sorrell, M. F. et al. (1999) Conversion of acetaldehyde-protein adduct epitopes from a nonreduced to a reduced phenotype by antigen processing cells. Alcoholism: Clinical and Experimental Research 23, 657-663.
16. Moncada C., Torres V., Varghese G. et al. (1994) Ethanol-derived immunoreactive species formed by free radical mechanisms. Molecular Pharmacology 46, 786-791.
17. Nicholls, R. M., Fowles, L. F., Worrall, S. et al. (1994) Distribution and turnover of acetaldehyde-modified proteins in liver and blood of ethanol-fed rats. Alcohol and Alcoholism 29, 149-157.
18. Niemela, O., Parkkila, S., Pasanen, M. et al. (1999) Induction of cytochrome P450 enzymes and generation of protein-aldehyde adducts are associated with sex-dependent sensitivity to alcohol-induced liver disease in micropigs. Hepatology 30, 1011-1017.
19. Niemela, O., Parkkila, S., Koll, M. et al. (2002) Generation of protein adducts with malondialdehyde and acetaldehyde in muscles with predominantly type I or type II fibers in rats exposed to ethanol and the acetaldehyde dehydrogenase inhibitor cyanamide. American Journal of Clinical Nutrition 76, 668-674.
20. Nilsson, G. E. (1988) A comparative study of aldehyde dehydrogenase and alcohol dehydrogenase activities in crucian carp and three other vertebrates: Apparent adaptations to ethanol production. Journal of Comparative Physiology B, Biochemical, Systemic, and Environmental Physiology 158, 479-485.
21. Preedy, V. R., Adachi, J., Peters, T. J. et al. (2001a) Recent advances in the pathology of alcoholic myopathy. Alcoholism: Clinical and Experimental Research 25, 54S-59S.
22. Preedy, V. R., Adachi, J., Ueno, Y. et al. (2001b) Alcoholic skeletal muscle myopathy: Definitions, features, contribution of neuropathy, impact and diagnosis. European Journal of Neurology 8, 677-687.
23. Preedy, V. R., Paice, A., Mantle, D. et al. (2001c) Alcoholic myopathy: Biochemical mechanisms. Drug and Alcohol Dependence 63, 199-205.
24. Preedy, V. R., Peters, T. J. and Adachi, J. (2001d) Pathogenic mechanisms in alcoholic myopathy, in Alcohol in health and disease (Agarwal DP and Seitz HK eds) pp 243-259, Marcel Dekker Inc, New York.
25. Pron'ko, P. S., Kuz'mich, A. B. and Abakumov, G. Z. (1999) Effect of alcohol intoxication and aldehyde dehydrogenase inhibitors on lipid peroxidation in rat liver. (Russian). Ukrainskii Biokhimicheskii Zhurnal 71, 79-83.
26. Rolla, R., Vay, D., Mottaran, E. et al. (2000) Detection of circulating antibodies against malondialdehyde-acetaldehyde adducts in patients with alcohol-induced liver disease. Hepatology 31, 878-884.
27. Sacanella, E., Fernandez-Sola, J., Cofan, M. et al. (1995) Chronic alcoholic myopathy: Diagnostic clues and relationship with other ethanol-related diseases. Quarterly Journal of Medicine 88, 811-817.
28. Salaspuro, M. (1997) Microbial metabolism of ethanol and acetaldehyde and clinical consequences. Addiction Biology 2, 35-46.
29. Seitz, H. and Poschl, G. (1997) Alcohol and gastrointestinal cancer: Pathogenic mechanisms. Addiction Biology 2, 19-33.
30. Singh, R., Leuratti, C., Josyula, S. et al. (2001) Lobe-specific increases in malondialdehyde DNA adduct formation in the livers of mice following infection with Helicobacter hepaticus. Carcinogenesis. 22, 1281-1287.
31. Smith, C., Stamm, S. C., Riggs, J. E. et al. (2000) Ethanol-mediated CYP1A1/2 induction in rat skeletal muscle tissue. Experimental and Molecular Pathology 69, 223-232.
32. Stewart, M. J., Malek, K and Crabb, D. W. (1996) Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues. Journal of Investigative Medicine 44, 42-46.
33. Thiele, G. M., Wegter, K. M., Sorrell, M. F. et al. (1994) Specificity to N-ethyl lysine of a monoclonal antibody to acetaldehyde-modified proteins prepared under reducing conditions. Biochemical Pharmacology 48, 183-189.
34. Thiele, G. M., Worrall, S., Tuma, D. J. et al. (2001) The chemistry and biological effects of malondialdehyde-acetaldehyde adducts. Alcoholism: Clinical and Experimental Research 25, 218S-224S.
35. Tuma, D. J., Newman, B. S., Donohue, T. M. Jr et al. (1987) Covalent binding of acetaldehyde to proteins: Participation of lysine residues. Alcoholism: Clinical and Experimental Research 11, 579-584.
36. Tuma, D. J., Thiele, G. M., Xu, D. et al. (1996) Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration. Hepatology 23, 872-880.
37. Vendemiale, G., Grattagliano, I., Signorile, A. et al. (1998) Ethanol-induced changes of intracellular thiol compartmentation and protein redox status in the rat liver: Effect of tauroursodeoxycholate. Journal of Hepatology 28, 46-53.
38. Worrall, S. and Thiele, G. M. (2001) Protein modification in ethanol toxicity. Adverse Drug Reactions and Toxicological Reviews 20, 133-159.
39. Worrall, S., De Jersey, J., Shanley, B. C. et al. (1989) Ethanol induces the production of antibodies to acetaldehyde-modified epitopes in rats. Alcohol and Alcoholism 217, 217-223.
40. Worrall, S., De Jersey, J., Shanley, B. C. et al. (1990) Antibodies against acetaldehyde-modified epitopes: Presence in alcoholic, non-alcoholic liver disease and control subjects. Alcohol and Alcoholism 25, 509-517.
41. Worrall, S., de Jersey, J., Nicholls, R. M. et al. (1993) Acetaldehyde/ protein interactions: Are they involved in the pathogenesis of alcoholic liver disease? Digestive Diseases 11, 265-277.
42. Worrall, S., De Jersey, J., Shanley, B. C. et al. (1994) Anti-acetaldehyde adduct antibodies generated by ethanol-fed rats react with reduced and unreduced acetaldehyde-modified proteins. Alcohol and Alcoholism 29, 43-50.
43. Worrall, S., de Jersey, J. and Wilce, P. A. (2000a) Comparison of the formation of proteins modified by direct and indirect metabolites of ethanol in the liver and blood of rats fed the Lieber-DeCarli diet. Alcohol and Alcoholism 35, 164-170.
44. Worrall, S., Richardson, P. J. and Preedy, V. R. (2000b) Experimental heart muscle damage in alcohol feeding is associated with increased amounts of reduced- and unreduced-acetaldehyde, and malondialdehyde-acetaldehyde protein adducts. Addiction Biology 5, 421-427.
45. Worrall, S., Niemela, O., Parkkila, S. et al. (2001) Protein adducts in type I and type II fibre predominant muscles of the ethanol-fed rat: preferential localisation in the sarcolemmal and subsarcolemmal region. European Journal of Clinical Investigation 31, 723-730.
46. Xu, D., Thiele, G. M., Kearley, M. L. et al. (1997) Epitope characterisation of malondialdehyde-acetaldehyde adducts using an enzyme linked immunosorbent assay. Chemical Research in Toxicology 10, 978-986.