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Volumn 13, Issue 11, 2012, Pages 5333-5338

Vitamin B6 deficiency, Genome instability and cancer

Author keywords

Epigenetics; Folate; Genome; Homocysteine; Vitamin B6

Indexed keywords


EID: 84874097961     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2012.13.11.5333     Document Type: Review
Times cited : (34)

References (82)
  • 1
    • 47249150529 scopus 로고    scopus 로고
    • Family history of prostate cancer and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
    • Ahn J, Moslehi R, Weinstein SJ, Snyder K, Virtamo J, Albanes D (2008). Family history of prostate cancer and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study. Int J Cancer, 123, 1154-9.
    • (2008) Int J Cancer , vol.123 , pp. 1154-1159
    • Ahn, J.1    Moslehi, R.2    Weinstein, S.J.3    Snyder, K.4    Virtamo, J.5    Albanes, D.6
  • 2
    • 80054690699 scopus 로고    scopus 로고
    • The enzymes of the transsulfuration pathways: active-site characterizations
    • Aitken SM, Lodha PH, Morneau DJ (2011). The enzymes of the transsulfuration pathways: active-site characterizations. Biochim Biophys Acta, 1814, 1511-7.
    • (2011) Biochim Biophys Acta , vol.1814 , pp. 1511-1517
    • Aitken, S.M.1    Lodha, P.H.2    Morneau, D.J.3
  • 3
    • 0033427595 scopus 로고    scopus 로고
    • Micronutrient deficiencies
    • A major cause of DNA damage
    • Ames BN (1999). Micronutrient deficiencies. A major cause of DNA damage. Ann N Y Acad Sci, 889, 87-106.
    • (1999) Ann N Y Acad Sci , vol.889 , pp. 87-106
    • Ames, B.N.1
  • 4
    • 0035906343 scopus 로고    scopus 로고
    • DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
    • Ames BN (2001). DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res, 18, 7-20.
    • (2001) Mutat Res , vol.18 , pp. 7-20
    • Ames, B.N.1
  • 5
    • 67649225407 scopus 로고    scopus 로고
    • SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis
    • Anderson DD, Stover PJ (2009). SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis. PLoS One, 4, e5839
    • (2009) PLoS One , vol.4
    • Anderson, D.D.1    Stover, P.J.2
  • 6
    • 84863421311 scopus 로고    scopus 로고
    • Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis
    • Anderson DD, Woeller CF, Chiang EP, Shane B, Stover PJ (2012) Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis. J Biol Chem, 287, 7051-62.
    • (2012) J Biol Chem , vol.287 , pp. 7051-7062
    • Anderson, D.D.1    Woeller, C.F.2    Chiang, E.P.3    Shane, B.4    Stover, P.J.5
  • 7
    • 84857684388 scopus 로고    scopus 로고
    • Serine hydroxymethyltransferase from the cold adapted microorganism psychromonas ingrahamii: a low temperature active enzyme with broad substrate specificity
    • Angelaccio S, Florio R, Consalvi V, Festa G, Pascarella S (2012). Serine hydroxymethyltransferase from the cold adapted microorganism psychromonas ingrahamii: a low temperature active enzyme with broad substrate specificity. Int J Mol Sci, 13, 1314-26.
    • (2012) Int J Mol Sci , vol.13 , pp. 1314-1326
    • Angelaccio, S.1    Florio, R.2    Consalvi, V.3    Festa, G.4    Pascarella, S.5
  • 8
    • 84866399063 scopus 로고    scopus 로고
    • Acid sphingomyelinase gene knockout ameliorates hyperhomocysteinemic glomerular injury in mice lacking cystathionine-β-synthase
    • Boini KM, Xia M, Abais JM, et al (2012). Acid sphingomyelinase gene knockout ameliorates hyperhomocysteinemic glomerular injury in mice lacking cystathionine-β-synthase. PLoS One, 7, e45020.
    • (2012) PLoS One , vol.7
    • Boini, K.M.1    Xia, M.2    Abais, J.M.3
  • 9
    • 84860389588 scopus 로고    scopus 로고
    • PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism
    • Bourquin F, Capitani G, Grütter MG (2011). PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism. Protein Sci, 20, 1492-508.
    • (2011) Protein Sci , vol.20 , pp. 1492-1508
    • Bourquin, F.1    Capitani, G.2    Grütter, M.G.3
  • 10
    • 80054741782 scopus 로고    scopus 로고
    • Pyridoxine supply in human development
    • Bowling FG (2011). Pyridoxine supply in human development. Semin Cell Dev Biol, 22, 611-8.
    • (2011) Semin Cell Dev Biol , vol.22 , pp. 611-618
    • Bowling, F.G.1
  • 11
    • 15744377644 scopus 로고    scopus 로고
    • Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway
    • Burns KE, Xiang Y, Kinsland CL, McLafferty FW, Begley TP (2005). Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway. J Am Chem Soc, 127, 3682-3.
    • (2005) J Am Chem Soc , vol.127 , pp. 3682-3683
    • Burns, K.E.1    Xiang, Y.2    Kinsland, C.L.3    McLafferty, F.W.4    Begley, T.P.5
  • 12
    • 80053295710 scopus 로고    scopus 로고
    • Dietary intake of vitamin B(6) and risk of breast cancer in Taiwanese women
    • Chou YC, Chu CH, Wu MH, et al (2011). Dietary intake of vitamin B(6) and risk of breast cancer in Taiwanese women. J Epidemiol, 21, 329-36.
    • (2011) J Epidemiol , vol.21 , pp. 329-336
    • Chou, Y.C.1    Chu, C.H.2    Wu, M.H.3
  • 13
    • 7244221348 scopus 로고    scopus 로고
    • DNA methylation, cancer susceptibility, and nutrient interactions
    • Cindy DD, Eric OU (2004). DNA methylation, cancer susceptibility, and nutrient interactions. Exp Biol Med, 229, 988-95.
    • (2004) Exp Biol Med , vol.229 , pp. 988-995
    • Cindy, D.D.1    Eric, O.U.2
  • 14
    • 84866304905 scopus 로고    scopus 로고
    • Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults
    • Clifford AJ, Chen K, McWade L, et al (2012). Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults. J Nutr, 142, 1764-71.
    • (2012) J Nutr , vol.142 , pp. 1764-1771
    • Clifford, A.J.1    Chen, K.2    McWade, L.3
  • 15
    • 79953228534 scopus 로고    scopus 로고
    • In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed
    • Daidone F, Florio R, Rinaldo S, et al (2011). In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. Eur J Med Chem, 46, 1616-21.
    • (2011) Eur J Med Chem , vol.46 , pp. 1616-1621
    • Daidone, F.1    Florio, R.2    Rinaldo, S.3
  • 16
    • 84874033637 scopus 로고    scopus 로고
    • Murine models of hyperhomocysteinemia and their vascular phenotypes
    • Dayal S, Lentz SR (2011). Murine models of hyperhomocysteinemia and their vascular phenotypes. Mol Genet Metab, 102, 126-33.
    • (2011) Mol Genet Metab , vol.102 , pp. 126-133
    • Dayal, S.1    Lentz, S.R.2
  • 17
    • 84860867247 scopus 로고    scopus 로고
    • Biomedical aspects of pyridoxal 5'-phosphate availability
    • di Salvo ML, Safo MK, Contestabile R (2012). Biomedical aspects of pyridoxal 5'-phosphate availability. Front Biosci, 4, 897-913.
    • (2012) Front Biosci , vol.4 , pp. 897-913
    • di Salvo, M.L.1    Safo, M.K.2    Contestabile, R.3
  • 19
    • 44649202769 scopus 로고    scopus 로고
    • Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation
    • Feng Q, Kalari K, Fridley BL, et al (2008). Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation. Mol Genet Metab, 94, 326-35.
    • (2008) Mol Genet Metab , vol.94 , pp. 326-335
    • Feng, Q.1    Kalari, K.2    Fridley, B.L.3
  • 20
    • 51849127760 scopus 로고    scopus 로고
    • Folate-mediated one-carbon metabolism
    • Fox JT, Stover PJ (2008). Folate-mediated one-carbon metabolism. Vitam Horm, 79, 1-44.
    • (2008) Vitam Horm , vol.79 , pp. 1-44
    • Fox, J.T.1    Stover, P.J.2
  • 21
    • 84859740079 scopus 로고    scopus 로고
    • Corticoadrenal activity in rat regulates betainehomocysteine S-methyltransferase expression with opposite effects in liver and kidney
    • Fridman O, Morales AV, Bortoni LE, Turk-Noceto PC, Prieto EA (2012). Corticoadrenal activity in rat regulates betainehomocysteine S-methyltransferase expression with opposite effects in liver and kidney. J Biosci, 37, 115-23.
    • (2012) J Biosci , vol.37 , pp. 115-123
    • Fridman, O.1    Morales, A.V.2    Bortoni, L.E.3    Turk-Noceto, P.C.4    Prieto, E.A.5
  • 22
    • 84870434160 scopus 로고    scopus 로고
    • Prognostic impact of vitamin b6 metabolism in lung cancer
    • Galluzzi L, Vitale I, Senovilla L, Olaussen KA (2012), Prognostic impact of vitamin b6 metabolism in lung cancer. Cell Rep, 2, 257-69.
    • (2012) Cell Rep , vol.2 , pp. 257-269
    • Galluzzi, L.1    Vitale, I.2    Senovilla, L.3    Olaussen, K.A.4
  • 23
    • 34447321068 scopus 로고    scopus 로고
    • Food, nutrient and heterocyclic amine intake and the risk of bladder cancer
    • García-Closas R, García-Closas M, Kogevinas M, et al (2007). Food, nutrient and heterocyclic amine intake and the risk of bladder cancer. Eur J Cancer, 43, 1731-40.
    • (2007) Eur J Cancer , vol.43 , pp. 1731-1740
    • García-Closas, R.1    García-Closas, M.2    Kogevinas, M.3
  • 24
    • 0027223085 scopus 로고
    • Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization
    • Garrow TA, Brenner AA, Whitehead VM, et al (1993). Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J Biol Chem, 268, 11910-6.
    • (1993) J Biol Chem , vol.268 , pp. 11910-11916
    • Garrow, T.A.1    Brenner, A.A.2    Whitehead, V.M.3
  • 25
    • 0032515921 scopus 로고    scopus 로고
    • Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene
    • Girgis S, Nasrallah IM, Suh JR, et al (1998). Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene. Gene, 210, 315-24.
    • (1998) Gene , vol.210 , pp. 315-324
    • Girgis, S.1    Nasrallah, I.M.2    Suh, J.R.3
  • 26
    • 84863024767 scopus 로고    scopus 로고
    • Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells
    • Guo H, Gai JW, Wang Y, Jin HF, Du JB, Jin J (2012). Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells. Urology, 79, 483.e1-5.
    • (2012) Urology , vol.79
    • Guo, H.1    Gai, J.W.2    Wang, Y.3    Jin, H.F.4    Du, J.B.5    Jin, J.6
  • 27
    • 53849112321 scopus 로고    scopus 로고
    • Serine hydroxymethyl transferase from Streptococcus thermophilus and L-threonine aldolase from Escherichia coli as stereocomplementary biocatalysts for the synthesis of betahydroxy- alpha,omega-diamino acid derivatives
    • Gutierrez ML, Garrabou X, Agosta E, et al (2008). Serine hydroxymethyl transferase from Streptococcus thermophilus and L-threonine aldolase from Escherichia coli as stereocomplementary biocatalysts for the synthesis of betahydroxy- alpha,omega-diamino acid derivatives. Chemistry, 14, 4647-56.
    • (2008) Chemistry , vol.14 , pp. 4647-4656
    • Gutierrez, M.L.1    Garrabou, X.2    Agosta, E.3
  • 28
    • 0030833905 scopus 로고    scopus 로고
    • Changes in vitamin B6 status indicators of women fed a constant protein diet with varying levels of vitamin B6
    • Hansen CM, Leklem JE, Miller LT (1997). Changes in vitamin B6 status indicators of women fed a constant protein diet with varying levels of vitamin B6. Am J Clin Nutr, 66, 1379-87.
    • (1997) Am J Clin Nutr , vol.66 , pp. 1379-1387
    • Hansen, C.M.1    Leklem, J.E.2    Miller, L.T.3
  • 29
    • 0035313298 scopus 로고    scopus 로고
    • Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men
    • Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al (2001). Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol, 153, 688-94.
    • (2001) Am J Epidemiol , vol.153 , pp. 688-694
    • Hartman, T.J.1    Woodson, K.2    Stolzenberg-Solomon, R.3
  • 30
    • 84862804459 scopus 로고    scopus 로고
    • Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization
    • Hebbring SJ, Chai Y, Ji Y, et al (2012). Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization. J Neurochem, 120, 881-90.
    • (2012) J Neurochem , vol.120 , pp. 881-890
    • Hebbring, S.J.1    Chai, Y.2    Ji, Y.3
  • 31
    • 0037064008 scopus 로고    scopus 로고
    • Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses
    • Herbig K, Chiang EP, Lee LR, et al (2002). Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. J Biol Chem, 277, 38381-9.
    • (2002) J Biol Chem , vol.277 , pp. 38381-38389
    • Herbig, K.1    Chiang, E.P.2    Lee, L.R.3
  • 32
    • 75749143884 scopus 로고    scopus 로고
    • Vitamin B6: a molecule for human health
    • Hellmann H, Mooney S (2010). Vitamin B6: a molecule for human health? Molecules, 15, 442-59. Ink SL, Mehansho H, Henderson LVM (1982). The binding of
    • (2010) Molecules , vol.15 , pp. 442-459
    • Hellmann, H.1    Mooney, S.2
  • 34
    • 64749104195 scopus 로고    scopus 로고
    • Arabidopsis photorespiratory serine hydroxymethyltransferase activity requires the mitochondrial accumulation of ferredoxin-dependent glutamate synthase
    • Jamai A, Salomé PA, Schilling SH, Weber AP, McClung CR (2009). Arabidopsis photorespiratory serine hydroxymethyltransferase activity requires the mitochondrial accumulation of ferredoxin-dependent glutamate synthase. Plant Cell, 21, 595-606
    • (2009) Plant Cell , vol.21 , pp. 595-606
    • Jamai, A.1    Salomé, P.A.2    Schilling, S.H.3    Weber, A.P.4    McClung, C.R.5
  • 35
    • 77951484974 scopus 로고    scopus 로고
    • A pilot trial comparing the availability of vitamins C, B6, and B12 from a vitamin-fortified water and food source in humans
    • Kalman DS, Lou L, Schwartz HI, Feldman S, Krieger DR (2009) A pilot trial comparing the availability of vitamins C, B6, and B12 from a vitamin-fortified water and food source in humans. Int J Food Sci Nutr, 60, 114-24.
    • (2009) Int J Food Sci Nutr , vol.60 , pp. 114-124
    • Kalman, D.S.1    Lou, L.2    Schwartz, H.I.3    Feldman, S.4    Krieger, D.R.5
  • 36
    • 0642334508 scopus 로고    scopus 로고
    • Diet and nutrition in urologic cancer
    • Kamat AM, Lamm DL (2000). Diet and nutrition in urologic cancer. W V Med J, 96, 449-54.
    • (2000) W V Med J , vol.96 , pp. 449-454
    • Kamat, A.M.1    Lamm, D.L.2
  • 37
    • 1242351242 scopus 로고    scopus 로고
    • Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes
    • Kannan K, Jain SK (2004). Effect of vitamin B6 on oxygen radicals, mitochondrial membrane potential, and lipid peroxidation in H2O2-treated U937 monocytes. Radic Biol Med, 36, 423-8.
    • (2004) Radic Biol Med , vol.36 , pp. 423-428
    • Kannan, K.1    Jain, S.K.2
  • 38
    • 80054680193 scopus 로고    scopus 로고
    • PLPdependent enzymes as potential drug targets for protozoan diseases
    • Kappes B, Tews I, Binter A, Macheroux P (2011). PLPdependent enzymes as potential drug targets for protozoan diseases. Biochim Biophys Acta, 1814, 1567-76.
    • (2011) Biochim Biophys Acta , vol.1814 , pp. 1567-1576
    • Kappes, B.1    Tews, I.2    Binter, A.3    Macheroux, P.4
  • 39
    • 84863835216 scopus 로고    scopus 로고
    • Association between genetic variants in DNA and histone methylation and telomere length
    • Kim S, Parks CG, Xu Z, et al (2012). Association between genetic variants in DNA and histone methylation and telomere length. PLoS One, 7, e40504. 10.
    • (2012) PLoS One , vol.7
    • Kim, S.1    Parks, C.G.2    Xu, Z.3
  • 40
    • 84874026775 scopus 로고    scopus 로고
    • Quantification of homocysteine-related metabolites and the role of betainehomocysteine S-methyltransferase in HepG2 cells
    • Kořínek M, Sístek V, Mládková J, et al (2012). Quantification of homocysteine-related metabolites and the role of betainehomocysteine S-methyltransferase in HepG2 cells. Biomed Chromatogr, 31, 15-20.
    • (2012) Biomed Chromatogr , vol.31 , pp. 15-20
    • Kořínek, M.1    Sístek, V.2    Mládková, J.3
  • 41
    • 33746588246 scopus 로고    scopus 로고
    • Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G diets
    • Lima CP, Davis SR, Mackey AD, et al (2006). Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G diets. J Nutr, 136, 2141-7.
    • (2006) J Nutr , vol.136 , pp. 2141-2147
    • Lima, C.P.1    Davis, S.R.2    Mackey, A.D.3
  • 42
    • 77949539302 scopus 로고    scopus 로고
    • Vitamin B6 and risk of colorectal cancer: a meta-analysis of prospective studies
    • Larsson SC, Orsini N, Wolk A (2010). Vitamin B6 and risk of colorectal cancer: a meta-analysis of prospective studies. JAMA, 303, 1077-83.
    • (2010) JAMA , vol.303 , pp. 1077-1083
    • Larsson, S.C.1    Orsini, N.2    Wolk, A.3
  • 43
    • 84865989620 scopus 로고    scopus 로고
    • Hyperhomocysteinemia is a risk factor for colorectal adenoma in women
    • Lim YJ, Kim JH, Park SK (2012). Hyperhomocysteinemia is a risk factor for colorectal adenoma in women. J Clin Biochem Nutr, 51, 132-5.
    • (2012) J Clin Biochem Nutr , vol.51 , pp. 132-135
    • Lim, Y.J.1    Kim, J.H.2    Park, S.K.3
  • 44
    • 84862122819 scopus 로고    scopus 로고
    • Effect of dietary supplementation with folate on choline deficiencyinduced hyperhomocysteinemia in rats
    • Liu Y, Liu YQ, Morita T, Mori M, Sugiyama K (2012). Effect of dietary supplementation with folate on choline deficiencyinduced hyperhomocysteinemia in rats. J Nutr Sci Vitaminol (Tokyo), 58, 20-8.
    • (2012) J Nutr Sci Vitaminol (Tokyo) , vol.58 , pp. 20-28
    • Liu, Y.1    Liu, Y.Q.2    Morita, T.3    Mori, M.4    Sugiyama, K.5
  • 45
    • 79960142102 scopus 로고    scopus 로고
    • Vitamin B6: a challenging link between nutrition and inflammation in CVD
    • Lotto V, Choi SW, Friso S (2011). Vitamin B6: a challenging link between nutrition and inflammation in CVD. Br J Nutr, 106, 183-95.
    • (2011) Br J Nutr , vol.106 , pp. 183-195
    • Lotto, V.1    Choi, S.W.2    Friso, S.3
  • 46
    • 0022151825 scopus 로고
    • Relationship between body store of vitamin B6 and plasma pyridoxal-P clearance: metabolic balance studies in humans
    • Lui A, Lumeng L, Aronoff GR, et al (1985). Relationship between body store of vitamin B6 and plasma pyridoxal-P clearance: metabolic balance studies in humans. J Lab Clin Med, 106, 491-7.
    • (1985) J Lab Clin Med , vol.106 , pp. 491-497
    • Lui, A.1    Lumeng, L.2    Aronoff, G.R.3
  • 47
    • 83755181500 scopus 로고    scopus 로고
    • Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA
    • MacFarlane AJ, Anderson DD, Flodby P, et al (2011). Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA. J Biol Chem, 286, 44015-22.
    • (2011) J Biol Chem , vol.286 , pp. 44015-44022
    • MacFarlane, A.J.1    Anderson, D.D.2    Flodby, P.3
  • 48
    • 54449100192 scopus 로고    scopus 로고
    • Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice
    • MacFarlane AJ, Liu X, Perry CA, et al (2008). Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice. J Biol Chem, 283, 25846-53.
    • (2008) J Biol Chem , vol.283 , pp. 25846-25853
    • MacFarlane, A.J.1    Liu, X.2    Perry, C.A.3
  • 49
    • 84858279961 scopus 로고    scopus 로고
    • Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk
    • Maclean KN, Jiang H, Greiner LS, Allen RH, Stabler SP (2012). Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk. Mol Genet Metab, 105, 395-403
    • (2012) Mol Genet Metab , vol.105 , pp. 395-403
    • Maclean, K.N.1    Jiang, H.2    Greiner, L.S.3    Allen, R.H.4    Stabler, S.P.5
  • 50
    • 80054689577 scopus 로고    scopus 로고
    • Pyridoxal-5'-phosphate-dependent enzymes involved in biotin biosynthesis: structure, reaction mechanism and inhibition
    • Mann S, Ploux O (2011). Pyridoxal-5'-phosphate-dependent enzymes involved in biotin biosynthesis: structure, reaction mechanism and inhibition. Biochim Biophys Acta, 1814, 1459-66.
    • (2011) Biochim Biophys Acta , vol.1814 , pp. 1459-1466
    • Mann, S.1    Ploux, O.2
  • 51
    • 0037152677 scopus 로고    scopus 로고
    • Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study
    • Michaud DS, Pietinen P, Taylor PR, et al (2002). Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study. Br J Cancer, 87, 960-5.
    • (2002) Br J Cancer , vol.87 , pp. 960-965
    • Michaud, D.S.1    Pietinen, P.2    Taylor, P.R.3
  • 52
    • 77953017808 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and the role of B vitamins in cancer
    • Mihaela Jurdana (2010). Hyperhomocysteinemia and the role of B vitamins in cancer. Nadja Plazar and Radiol Oncol, 44, 79-85.
    • (2010) Nadja Plazar and Radiol Oncol , vol.44 , pp. 79-85
    • Mihaela Jurdana1
  • 53
    • 77949650545 scopus 로고    scopus 로고
    • Vitamin B6: Killing two birds with one stone
    • Mooney S, Hellmann H (2010). Vitamin B6: Killing two birds with one stone? Phytochemistry, 71, 495-501
    • (2010) Phytochemistry , vol.71 , pp. 495-501
    • Mooney, S.1    Hellmann, H.2
  • 54
    • 79955821925 scopus 로고    scopus 로고
    • Folate and choline metabolism gene variants and development of uterine cervical carcinoma
    • Mostowska A, Myka M, Lianeri M, Roszak A, Jagodziński PP (2011). Folate and choline metabolism gene variants and development of uterine cervical carcinoma. Clin Biochem, 44, 596-600.
    • (2011) Clin Biochem , vol.44 , pp. 596-600
    • Mostowska, A.1    Myka, M.2    Lianeri, M.3    Roszak, A.4    Jagodziński, P.P.5
  • 55
    • 77954443763 scopus 로고    scopus 로고
    • Vitamin B6-magnesium treatment for autism: the current status of the research
    • Murza KA, Pavelko SL, Malani MD, Nye C (2010). Vitamin B6-magnesium treatment for autism: the current status of the research. Magnes Res, 23, 115-7.
    • (2010) Magnes Res , vol.23 , pp. 115-117
    • Murza, K.A.1    Pavelko, S.L.2    Malani, M.D.3    Nye, C.4
  • 56
    • 0034053112 scopus 로고    scopus 로고
    • Selected micronutrients and oral and pharyngeal cancer
    • Negri E, Franceschi S, Bosetti C, et al (2000). Selected micronutrients and oral and pharyngeal cancer. Int J Cancer, 86, 122-7.
    • (2000) Int J Cancer , vol.86 , pp. 122-127
    • Negri, E.1    Franceschi, S.2    Bosetti, C.3
  • 57
    • 0020714345 scopus 로고
    • Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei
    • Noguchi H, Prem veer Reddy G, Pardee AB (1983). Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei. Cell, 32, 443-51.
    • (1983) Cell , vol.32 , pp. 443-451
    • Noguchi, H.1    Prem Veer Reddy, G.2    Pardee, A.B.3
  • 58
    • 70450170797 scopus 로고    scopus 로고
    • Dietary intake of the water-soluble vitamins B1, B2, B6, B12 and C in 10 countries in the European Prospective Investigation into Cancer and Nutrition
    • Olsen A, Halkjaer J, van Gils CH, et al (2009). Dietary intake of the water-soluble vitamins B1, B2, B6, B12 and C in 10 countries in the European Prospective Investigation into Cancer and Nutrition. Eur J Clin Nutr, 63, S122-49.
    • (2009) Eur J Clin Nutr , vol.63
    • Olsen, A.1    Halkjaer, J.2    van Gils, C.H.3
  • 59
    • 84863736217 scopus 로고    scopus 로고
    • Folate and choline metabolism gene variants in relation to ovarian cancer risk in the Polish population
    • Pawlik P, Mostowska A, Lianeri M, et al (2012). Folate and choline metabolism gene variants in relation to ovarian cancer risk in the Polish population. Mol Biol Rep, 39, 5553-60.
    • (2012) Mol Biol Rep , vol.39 , pp. 5553-5560
    • Pawlik, P.1    Mostowska, A.2    Lianeri, M.3
  • 60
    • 84855572230 scopus 로고    scopus 로고
    • A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma
    • Pellanda H, Namour F, Fofou-Caillierez M, et al (2012). A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma. Int J Biochem Cell Biol, 44, 385-92.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 385-392
    • Pellanda, H.1    Namour, F.2    Fofou-Caillierez, M.3
  • 61
    • 34248672559 scopus 로고    scopus 로고
    • Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells
    • Perry C, Yu S, Chen J, Matharu KS, Stover PJ (2007). Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells. Arch Biochem Biophys, 462, 21-7.
    • (2007) Arch Biochem Biophys , vol.462 , pp. 21-27
    • Perry, C.1    Yu, S.2    Chen, J.3    Matharu, K.S.4    Stover, P.J.5
  • 62
    • 84874085389 scopus 로고    scopus 로고
    • Human cystathionine beta-synthase (CBS) contains two classes of binding sites for S-adenosyl-L-methionine (SAM): complex regulation of CBS activity and stability by SAM
    • Pey AL, Majtan T, Sanchez-Ruiz JM, Kraus JP (2012). Human cystathionine beta-synthase (CBS) contains two classes of binding sites for S-adenosyl-L-methionine (SAM): complex regulation of CBS activity and stability by SAM. Biochem J, 18, 31-9.
    • (2012) Biochem J , vol.18 , pp. 31-39
    • Pey, A.L.1    Majtan, T.2    Sanchez-Ruiz, J.M.3    Kraus, J.P.4
  • 63
    • 65549130157 scopus 로고    scopus 로고
    • Intersubunit crosstalk in pyridoxal 5'-phosphate synthase, co-ordinated by the Cterminus of the synthase subunit
    • Raschle T, Speziga D, Kress W, et al (2008). Intersubunit crosstalk in pyridoxal 5'-phosphate synthase, co-ordinated by the Cterminus of the synthase subunit. J Biol Chem, 284, 7706-18.
    • (2008) J Biol Chem , vol.284 , pp. 7706-7718
    • Raschle, T.1    Speziga, D.2    Kress, W.3
  • 64
    • 78649595662 scopus 로고    scopus 로고
    • Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum
    • Read M, Müller IB, Mitchell SL, Sims PF, Hyde JE (2010). Dynamic subcellular localization of isoforms of the folate pathway enzyme serine hydroxymethyltransferase (SHMT) through the erythrocytic cycle of Plasmodium falciparum. Malar J, 9, 351.
    • (2010) Malar J , vol.9 , pp. 351
    • Read, M.1    Müller, I.B.2    Mitchell, S.L.3    Sims, P.F.4    Hyde, J.E.5
  • 65
    • 79952750270 scopus 로고    scopus 로고
    • Hydrogen sulfide generation in mammals: the molecular biology of cystathionine-β- synthase (CBS) and cystathionine-γ-lyase (CSE)
    • Renga B (2011).Hydrogen sulfide generation in mammals: the molecular biology of cystathionine-β- synthase (CBS) and cystathionine-γ-lyase (CSE). Inflamm Allergy Drug Targets, 10, 85-91.
    • (2011) Inflamm Allergy Drug Targets , vol.10 , pp. 85-91
    • Renga, B.1
  • 66
    • 80054715742 scopus 로고    scopus 로고
    • Mechanisms and structures of vitamin B(6)-dependent enzymes involved in deoxy sugar biosynthesis
    • Romo AJ, Liu HW (2011). Mechanisms and structures of vitamin B(6)-dependent enzymes involved in deoxy sugar biosynthesis. Biochim Biophys Acta, 1814, 1534-47.
    • (2011) Biochim Biophys Acta , vol.1814 , pp. 1534-1547
    • Romo, A.J.1    Liu, H.W.2
  • 67
    • 71849112061 scopus 로고    scopus 로고
    • Structural adaptation of serine hydroxymethyltransferase to low temperatures
    • Siglioccolo A, Bossa F, Pascarella S (2010). Structural adaptation of serine hydroxymethyltransferase to low temperatures. Int J Biol Macromol, 46, 37-46.
    • (2010) Int J Biol Macromol , vol.46 , pp. 37-46
    • Siglioccolo, A.1    Bossa, F.2    Pascarella, S.3
  • 69
    • 0031035739 scopus 로고    scopus 로고
    • Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene
    • Stover PJ, Chen LH, Suh JR, et al (1997). Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene. J Biol Chem, 272, 1842-8.
    • (1997) J Biol Chem , vol.272 , pp. 1842-1848
    • Stover, P.J.1    Chen, L.H.2    Suh, J.R.3
  • 71
    • 84874068898 scopus 로고    scopus 로고
    • Evaluation of the clastogenicity and anticlastogenicity of vitamin B6 in human lymphocyte cultures. Toxicol In Vitro. 2007. Konings EJ. Water-soluble vitamins.
    • Takeuchi PL, Antunes LM, Takahashi CS (2006). Evaluation of the clastogenicity and anticlastogenicity of vitamin B6 in human lymphocyte cultures. Toxicol In Vitro. 2007. Konings EJ. Water-soluble vitamins. J AOAC Int, 89, 285-8.
    • (2006) J AOAC Int , vol.89 , pp. 285-288
    • Takeuchi, P.L.1    Antunes, L.M.2    Takahashi, C.S.3
  • 72
    • 12344334763 scopus 로고    scopus 로고
    • Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes
    • Tanaka T, Tateno Y, Gojobori T (2005). Evolution of vitamin B6 (pyridoxine) metabolism by gain and loss of genes. Mol Biol Evol, 22, 243-5.
    • (2005) Mol Biol Evol , vol.22 , pp. 243-245
    • Tanaka, T.1    Tateno, Y.2    Gojobori, T.3
  • 73
    • 33745791496 scopus 로고    scopus 로고
    • Analysis of the Arabidopsis rsr4- 1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis
    • Wagner S, Bernhardt A, Leuendorf JE, et al (2006). Analysis of the Arabidopsis rsr4- 1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis. Plant Cell, 18, 1722-35.
    • (2006) Plant Cell , vol.18 , pp. 1722-1735
    • Wagner, S.1    Bernhardt, A.2    Leuendorf, J.E.3
  • 74
    • 84874026605 scopus 로고    scopus 로고
    • Polymorphisms of cytosolic serine hydroxymethyltransferase and risk of lung cancer: a case-control analysis
    • Wang L, Lu J, An J, et al (2007). Polymorphisms of cytosolic serine hydroxymethyltransferase and risk of lung cancer: a case-control analysis. Lung Cancer, 65, 196-205.
    • (2007) Lung Cancer , vol.65 , pp. 196-205
    • Wang, L.1    Lu, J.2    An, J.3
  • 75
    • 3843075064 scopus 로고    scopus 로고
    • Nutritional intakes in community-dwelling older Japanese adults: high intakes of energy and protein based on high consumption of fish, vegetables and fruits provide sufficient micronutrients
    • Watanabe R, Hanamori K, Kadoya H, Nishimuta M, Miyazaki H (2004). Nutritional intakes in community-dwelling older Japanese adults: high intakes of energy and protein based on high consumption of fish, vegetables and fruits provide sufficient micronutrients. J Nutr Sci Vitaminol (Tokyo), 50, 184-95.
    • (2004) J Nutr Sci Vitaminol (Tokyo) , vol.50 , pp. 184-195
    • Watanabe, R.1    Hanamori, K.2    Kadoya, H.3    Nishimuta, M.4    Miyazaki, H.5
  • 76
    • 0038124366 scopus 로고    scopus 로고
    • Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease
    • Weisberg IS, Park E, Ballman KV, et al (2003). Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease. Atherosclerosis, 167, 205-14.
    • (2003) Atherosclerosis , vol.167 , pp. 205-214
    • Weisberg, I.S.1    Park, E.2    Ballman, K.V.3
  • 77
    • 34547101719 scopus 로고    scopus 로고
    • Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway
    • Woeller CF, Anderson DD, Szebenyi DM, Stover PJ (2007). Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway. J Biol Chem, 282, 17623-31.
    • (2007) J Biol Chem , vol.282 , pp. 17623-17631
    • Woeller, C.F.1    Anderson, D.D.2    Szebenyi, D.M.3    Stover, P.J.4
  • 78
    • 79960175330 scopus 로고    scopus 로고
    • A novel approach to inhibit intracellular vitamin B6-dependent enzymes: proof of principle with human and plasmodium ornithine decarboxylase and human histidine decarboxylase
    • Wu F, Christen P, Gehring H (2011). A novel approach to inhibit intracellular vitamin B6-dependent enzymes: proof of principle with human and plasmodium ornithine decarboxylase and human histidine decarboxylase. FASEB J, 25, 2109-22.
    • (2011) FASEB J , vol.25 , pp. 2109-2122
    • Wu, F.1    Christen, P.2    Gehring, H.3
  • 80
    • 84864412265 scopus 로고    scopus 로고
    • Determination of L-methionine using methionine-specific dehydrogenase for diagnosis of homocystinuria due to cystathionine β-synthase deficiency
    • Yamasaki-Yashiki S, Tachibana S, Asano Y (2012). Determination of L-methionine using methionine-specific dehydrogenase for diagnosis of homocystinuria due to cystathionine β-synthase deficiency. Anal Biochem, 428, 143-9.
    • (2012) Anal Biochem , vol.428 , pp. 143-149
    • Yamasaki-Yashiki, S.1    Tachibana, S.2    Asano, Y.3
  • 81
    • 77955844910 scopus 로고    scopus 로고
    • Depleted folate pool and dysfunctional mitochondria associated with defective mitochondrial folate proteins sensitize Chinese ovary cell mutants to tert-butylhydroperoxide-induced oxidative stress and apoptosis
    • Ye YL, Chan YT, Liu HC, Lu HT, Huang RF (2010). Depleted folate pool and dysfunctional mitochondria associated with defective mitochondrial folate proteins sensitize Chinese ovary cell mutants to tert-butylhydroperoxide-induced oxidative stress and apoptosis. J Nutr Biochem, 21, 793-800.
    • (2010) J Nutr Biochem , vol.21 , pp. 793-800
    • Ye, Y.L.1    Chan, Y.T.2    Liu, H.C.3    Lu, H.T.4    Huang, R.F.5
  • 82
    • 84856438904 scopus 로고    scopus 로고
    • Functional variant in methionine synthase reductase intron-1 significantly increases the risk of congenital heart disease in the Han Chinese population
    • Zhao JY, Yang XY, Gong XH, et al (2012). Functional variant in methionine synthase reductase intron-1 significantly increases the risk of congenital heart disease in the Han Chinese population. Circulation, 125, 482-90.
    • (2012) Circulation , vol.125 , pp. 482-490
    • Zhao, J.Y.1    Yang, X.Y.2    Gong, X.H.3


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