Serine hydroxymethyltransferase anchors de Novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis

Journal of Biological Chemistry

Volumn 287, Issue 10, 2012, Pages 7051-7062

  Anderson, Donald D ^a   Woeller, Collynn F ^a   Chiang, En Pei ^b,c   Shane, Barry ^c   Stover, Patrick J ^a  

^a Cornell University ^*  (United States)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHETIC PATHWAY; COLOCALIZATION; COMPLEX FORMATIONS; DIHYDROFOLATE REDUCTASE; DNA REPLICATIONS; DNA SYNTHESISS; MAMMALIAN CELLS; MULTIENZYME COMPLEXES; NUCLEAR LAMINA; PROLIFERATING CELL NUCLEAR ANTIGENS; RATE LIMITING; REPLICATION FORK; SCAFFOLD PROTEIN; SERINE HYDROXYMETHYLTRANSFERASE; SYNTHESIS PATHWAYS; THYMIDYLATE SYNTHASE;

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; CELL PROLIFERATION; ENZYMES; MACHINERY;

DNA;

CYCLINE; DIHYDROFOLATE REDUCTASE; GLYCINE HYDROXYMETHYLTRANSFERASE; LAMIN B; LAMIN B1; SERINE HYDROXYMETHYLTRANSFERASE 1; SERINE HYDROXYMETHYLTRANSFERASE 2ALPHA; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPLICATION; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME LOCALIZATION; NUCLEAR LAMINA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION;

DNA; DNA REPAIR; DNA REPLICATION; GLYCINE HYDROXYMETHYLTRANSFERASE; HELA CELLS; HUMANS; MULTIENZYME COMPLEXES; NUCLEAR LAMINA; TETRAHYDROFOLATE DEHYDROGENASE; THYMIDINE MONOPHOSPHATE;

MAMMALIA;

EID: 84863421311     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.333120     Document Type: Article

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