메뉴 건너뛰기




Volumn 167, Issue 2, 2003, Pages 205-214

Investigations of a common genetic variant in betaine-homocysteine methyltransferase (BHMT) in coronary artery disease

Author keywords

Betaine; Betaine homocysteine methyltransferase; Cardiovascular disease; Genetic variants; Homocysteine

Indexed keywords

BETAINE HOMOCYSTEINE METHYLTRANSFERASE; FOLIC ACID; ISOENZYME; UNCLASSIFIED DRUG;

EID: 0038124366     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(03)00010-8     Document Type: Article
Times cited : (75)

References (31)
  • 1
    • 0029066299 scopus 로고
    • A quantitative assessment of plasma homocysteine as a risk factor for vascular disease
    • Boushey C., Beresford S.A.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. J. Am. Med. Assoc. 274:1995;1049-1057.
    • (1995) J. Am. Med. Assoc. , vol.274 , pp. 1049-1057
    • Boushey, C.1    Beresford, S.A.A.2    Omenn, G.S.3    Motulsky, A.G.4
  • 4
    • 0034743914 scopus 로고    scopus 로고
    • The 1298A→C polymorphism in methylenetetrahydrofolate reductase (MTHFR): In vitro expression and association with homocysteine
    • Weisberg I.S., Jacques P.F., Selhub J., Bostom A.G., Chen Z., Ellison R.C., Eckfeldt J.H., Rozen R. The 1298A→C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine. Atherosclerosis. 156:2001;409-415.
    • (2001) Atherosclerosis , vol.156 , pp. 409-415
    • Weisberg, I.S.1    Jacques, P.F.2    Selhub, J.3    Bostom, A.G.4    Chen, Z.5    Ellison, R.C.6    Eckfeldt, J.H.7    Rozen, R.8
  • 7
    • 0032763113 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease
    • Mager A., Lalezari S., Shohat T., Birnbaum Y., Adler Y., Magal N., Shohat M. Methylenetetrahydrofolate reductase genotypes and early-onset coronary artery disease. Circulation. 100:1999;2406-2410.
    • (1999) Circulation , vol.100 , pp. 2406-2410
    • Mager, A.1    Lalezari, S.2    Shohat, T.3    Birnbaum, Y.4    Adler, Y.5    Magal, N.6    Shohat, M.7
  • 8
    • 18344398980 scopus 로고    scopus 로고
    • The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation
    • Margaglione M., D'Andrea G., d'Addedda M., Giuliani N., Cappucci G., Iannaccone L., Veccione G., Grandone E., Brancaccio V., Di Minno G. The methylenetetrahydrofolate reductase TT677 genotype is associated with venous thrombosis independently of the coexistence of the FV Leiden and the prothrombin A20210 mutation. Thromb. Haemost. 79:1998;907-911.
    • (1998) Thromb. Haemost. , vol.79 , pp. 907-911
    • Margaglione, M.1    D'Andrea, G.2    D'Addedda, M.3    Giuliani, N.4    Cappucci, G.5    Iannaccone, L.6    Veccione, G.7    Grandone, E.8    Brancaccio, V.9    Di Minno, G.10
  • 9
    • 0033365197 scopus 로고    scopus 로고
    • The 'Thermolabile' variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother
    • Shields D.C., Kirke P.N., Mills J.L., Ramsbottom D., Molloy A.M., Burke H., Weir D.G., Scott J.M., Whitehead A.S. The 'Thermolabile' variant of methylenetetrahydrofolate reductase and neural tube defects: an evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother. Am. J. Hum. Genet. 64:1999;1045-1055.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 1045-1055
    • Shields, D.C.1    Kirke, P.N.2    Mills, J.L.3    Ramsbottom, D.4    Molloy, A.M.5    Burke, H.6    Weir, D.G.7    Scott, J.M.8    Whitehead, A.S.9
  • 10
    • 0034190659 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A huge review
    • Botto L.D., Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a huge review. Am. J. Epidemiol. 9:2000;862-877.
    • (2000) Am. J. Epidemiol. , vol.9 , pp. 862-877
    • Botto, L.D.1    Yang, Q.2
  • 11
    • 0032771090 scopus 로고    scopus 로고
    • Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: A systematic review
    • Ray J.G., Laskin C.A. Folic acid and homocyst(e)ine metabolic defects and the risk of placental abruption, pre-eclampsia and spontaneous pregnancy loss: a systematic review. Placenta. 20:1999;519-529.
    • (1999) Placenta , vol.20 , pp. 519-529
    • Ray, J.G.1    Laskin, C.A.2
  • 14
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydofolate reductase (MTHFR) associated with decreased enzyme activity
    • Weisberg I., Tran P., Christensen B., Sibani S., Rozen R. A second genetic polymorphism in methylenetetrahydofolate reductase (MTHFR) associated with decreased enzyme activity. Mol. Genet. Metab. 64:1998;169-172.
    • (1998) Mol. Genet. Metab. , vol.64 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 16
    • 10544249877 scopus 로고    scopus 로고
    • Human methionine synthase:cDNA cloning, chromosomal localization, and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders
    • Leclerc D., Campeau E., Goyette P., Adjalla C.E., Christensen B., Ross M., Eydoux P., Rosenblatt D.S., Rozen R., Gravel R.A. Human methionine synthase:cDNA cloning, chromosomal localization, and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Hum. Mol. Genet. 5:1996;1867-1874.
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1867-1874
    • Leclerc, D.1    Campeau, E.2    Goyette, P.3    Adjalla, C.E.4    Christensen, B.5    Ross, M.6    Eydoux, P.7    Rosenblatt, D.S.8    Rozen, R.9    Gravel, R.A.10
  • 17
    • 0346440989 scopus 로고    scopus 로고
    • Molecular biology of methionine synthase: Interrelationships with homocysteine and vascular disease
    • K. Robinson. Dordrecht, The Netherlands: Kluwer Academic Publishers
    • Banerjee R. Molecular biology of methionine synthase: interrelationships with homocysteine and vascular disease. Robinson K. Homocysteine and vascular disease. 2000;291-311 Kluwer Academic Publishers, Dordrecht, The Netherlands.
    • (2000) Homocysteine and vascular disease , pp. 291-311
    • Banerjee, R.1
  • 19
    • 0033912873 scopus 로고    scopus 로고
    • A common polymorphism in methionine synthase reductase increases risk for premature coronary artery disease
    • Brown C.A., McKinney K.Q., Kaufman J.S., Gravel R.A., Rozen R. A common polymorphism in methionine synthase reductase increases risk for premature coronary artery disease. J. Cardiovasc. Risk. 7:2000;197-200.
    • (2000) J. Cardiovasc. Risk , vol.7 , pp. 197-200
    • Brown, C.A.1    McKinney, K.Q.2    Kaufman, J.S.3    Gravel, R.A.4    Rozen, R.5
  • 20
    • 0031239784 scopus 로고    scopus 로고
    • Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene
    • Sunden S.L., Renduchintala M.S., Park E.I., Miklasz S.D., Garrow T.A. Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene. Arch. Biochem. Biophys. 345:1997;171-174.
    • (1997) Arch. Biochem. Biophys. , vol.345 , pp. 171-174
    • Sunden, S.L.1    Renduchintala, M.S.2    Park, E.I.3    Miklasz, S.D.4    Garrow, T.A.5
  • 21
    • 0032514889 scopus 로고    scopus 로고
    • Betaine-homocysteine methyltransferase is a developmentally regulated enzyme crystallin in rhesus monkey lens
    • Rao P.V., Garrow T.W., Garland J.F., Millian N.S., Zigler J.S. Betaine-homocysteine methyltransferase is a developmentally regulated enzyme crystallin in rhesus monkey lens. J. Biol. Chem. 273:1998;30669-30674.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30669-30674
    • Rao, P.V.1    Garrow, T.W.2    Garland, J.F.3    Millian, N.S.4    Zigler, J.S.5
  • 22
    • 0021220516 scopus 로고
    • Methionine metabolism in mammals. Distribution of homocysteine between competing pathways
    • Finkelstein J.D., Martin J.J. Methionine metabolism in mammals. Distribution of homocysteine between competing pathways. J. Biol. Chem. 259:1984;9508-9513.
    • (1984) J. Biol. Chem. , vol.259 , pp. 9508-9513
    • Finkelstein, J.D.1    Martin, J.J.2
  • 23
    • 0033583210 scopus 로고    scopus 로고
    • Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene
    • Park E.I., Garrow T.A. Interaction between dietary methionine and methyl donor intake on rat liver betaine-homocysteine methyltransferase gene expression and organization of the human gene. J. Biol. Chem. 274:1999;7816-7824.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7816-7824
    • Park, E.I.1    Garrow, T.A.2
  • 24
    • 0029995347 scopus 로고    scopus 로고
    • Treatment of hyperhomocysteinemia: Physiological basis
    • Kang S.-S. Treatment of hyperhomocysteinemia: physiological basis. J. Nutr. 126:1996;1273S-1275.
    • (1996) J. Nutr. , vol.126
    • Kang, S.-S.1
  • 25
    • 0029787429 scopus 로고    scopus 로고
    • Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase
    • Garrow T.A. Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase. J. Biol. Chem. 271:1996;22831-22838.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22831-22838
    • Garrow, T.A.1
  • 26
    • 0027487271 scopus 로고
    • Optimization of the single strand conformation polymorphism (SSCP) technique for detection of point mutations
    • Glavac D., Dean M. Optimization of the single strand conformation polymorphism (SSCP) technique for detection of point mutations. Hum. Mutat. 2:1993;404-414.
    • (1993) Hum. Mutat. , vol.2 , pp. 404-414
    • Glavac, D.1    Dean, M.2
  • 27
    • 0032147170 scopus 로고    scopus 로고
    • Human betaine-homocysteine methyltransferase is a zinc metalloenzyme
    • Millian N.S., Garrow T.A. Human betaine-homocysteine methyltransferase is a zinc metalloenzyme. Arch. Biochem. Biophys. 356:1998;93-98.
    • (1998) Arch. Biochem. Biophys. , vol.356 , pp. 93-98
    • Millian, N.S.1    Garrow, T.A.2
  • 28
    • 0037825389 scopus 로고    scopus 로고
    • Betaine-dependent remethylation
    • R. Carmel, & D.W. Jacobsen. Cambridge, UK: Cambridge University Press
    • Garrow T.A. Betaine-dependent remethylation. Carmel R., Jacobsen D.W. Homocysteine in Health and Disease. 2001;145-152 Cambridge University Press, Cambridge, UK.
    • (2001) Homocysteine in Health and Disease , pp. 145-152
    • Garrow, T.A.1
  • 29
    • 0033179315 scopus 로고    scopus 로고
    • Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase
    • Sowden M.P., Collins H.L., Smith H.C., Garrow T.A., Sparks J.D., Sparks C.E. Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase. Biochem. J. 341:1999;639-645.
    • (1999) Biochem. J. , vol.341 , pp. 639-645
    • Sowden, M.P.1    Collins, H.L.2    Smith, H.C.3    Garrow, T.A.4    Sparks, J.D.5    Sparks, C.E.6
  • 30
    • 0033730997 scopus 로고    scopus 로고
    • Betaine-homocysteine methyltransferase (BHMT): Genomic sequencing and relevance to hyperhomocysteinemia and vascular disease in humans
    • Heil SG, Lievers KJA, Boers GH, Verhoef P, den Heijer M, Trijbels FJM, Blom HJ. Betaine-homocysteine methyltransferase (BHMT): genomic sequencing and relevance to hyperhomocysteinemia and vascular disease in humans. Mol Genet Metab 2000;71:511-19.
    • (2000) Mol Genet Metab , vol.71 , pp. 511-519
    • Heil, S.G.1    Lievers, K.J.A.2    Boers, G.H.3    Verhoef, P.4    Den Heijer, M.5    Trijbels, F.J.M.6    Blom, H.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.