Inhibition of tau filament formation by conformational modulation

Journal of the American Chemical Society

Volumn 135, Issue 7, 2013, Pages 2853-2862

  Akoury, Elias ^a   Gajda, Michal ^a   Pickhardt, Marcus ^b   Biernat, Jacek ^b   Soraya, Pornsuwan ^a   Griesinger, Christian ^a   Mandelkow, Eckhard ^b,c   Zweckstetter, Markus ^a,b  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; FILAMENT FORMATION; MODE OF ACTION; PTHALOCYANINES; SMALL ANGLE X-RAY SCATTERING; SMALL MOLECULES; TAU PROTEINS;

MAGNETIC RESONANCE; MODULATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERS; PARAMAGNETISM; PROTEINS;

CONFORMATIONS;

OLIGOMER; ORGANIC COMPOUND; PTHALOCYANINE TETRASULFONATE; SULFONE DERIVATIVE; TAU PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; CIRCULAR DICHROISM; CONFORMATION; ELECTRON SPIN RESONANCE; LIGHT SCATTERING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN INTERACTION; X RAY;

ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TAU PROTEINS;

EID: 84874027197     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja312471h     Document Type: Article

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