The dynamic structure of filamentous Tau

Angewandte Chemie - International Edition

Volumn 50, Issue 48, 2011, Pages 11520-11524

  Bibow, Stefan ^a   Mukrasch, Marco D ^a   Chinnathambi, Subashchandrabose ^b,c   Biernat, Jacek ^b,c   Griesinger, Christian ^a   Mandelkow, Eckhard ^b,c   Zweckstetter, Markus ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^c CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

Author keywords

aggregation; Alzheimer disease; fuzzy coat; paired helical filament; tau protein

Indexed keywords

ALZHEIMER DISEASE; DYNAMIC STRUCTURE; FUZZY COAT; LONG RANGE INTERACTIONS; PAIRED HELICAL FILAMENTS; TAU PROTEINS;

AGGLOMERATION; AMINO ACIDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

NEURODEGENERATIVE DISEASES;

TAU PROTEIN;

ALZHEIMER DISEASE; ARTICLE; CHEMISTRY; CONFORMATION; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE;

ALZHEIMER DISEASE; HUMANS; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; TAU PROTEINS;

EID: 81755177762     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201105493     Document Type: Article

References (28)

1. C. Ballatore, V. M. Lee, J. Q. Trojanowski, Nat. Rev. Neurosci. 2007, 8, 663-672.
2. C. Haass, D. J. Selkoe, Nat. Rev. Mol. Cell Biol. 2007, 8, 101-112.
3. S. A. Small, K. Duff, Neuron 2008, 60, 534-542.
4. H. Braak, E. Braak, Acta Neuropathol. 1991, 82, 239-259.
5. J. Berriman, L. C. Serpell, K. A. Oberg, A. L. Fink, M. Goedert, R. A. Crowther, Proc. Natl. Acad. Sci. USA 2003, 100, 9034-9038.
6. O. C. Andronesi, M. vonBergen, J. Biernat, K. Seidel, C. Griesinger, E. Mandelkow, M. Baldus, J. Am. Chem. Soc. 2008, 130, 5922-5928.
7. C. M. Wischik, M. Novak, P. C. Edwards, A. Klug, W. Tichelaar, R. A. Crowther, Proc. Natl. Acad. Sci. USA 1988, 85, 4884-4888.
8. T. A. Schoenfeld, R. A. Obar, Int. Rev. Cytol. 1994, 151, 67-137.
9. M. Margittai, R. Langen, Proc. Natl. Acad. Sci. USA 2004, 101, 10278-10283.
10. A. Sillen, J. M. Wieruszeski, A. Leroy, A. B. Younes, I. Landrieu, G. Lippens, J. Am. Chem. Soc. 2005, 127, 10138-10139.
11. Y. Wang, S. Garg, E. M. Mandelkow, E. Mandelkow, Biochem. Soc. Trans. 2010, 38, 955-961.
12. N. E. LaPointe, G. Morfini, G. Pigino, I. N. Gaisina, A. P. Kozikowski, L. I. Binder, S. T. Brady, J. Neurosci. Res. 2009, 87, 440-451.
13. P. M. Horowitz, N. LaPointe, A. L. Guillozet-Bongaarts, R. W. Berry, L. I. Binder, Biochemistry 2006, 45, 12859-12866.
14. E. O. Stejskal, J. E. Tanner, J. Chem. Phys. 1965, 42, 288-292.
15. A. N. Garroway, J. Magn. Reson. 1982, 49, 168-171.
16. A. Sillen, J.-M. Wieruszeski, A. Leroy, A. B. Younes, I. Landrieu, G. Lippens, J. Am. Chem. Soc. 2005, 127, 10138-10139.
17. J. R. Gillespie, D. Shortle, J. Mol. Biol. 1997, 268, 170-184.
18. M. vonBergen, S. Barghorn, S. A. Muller, M. Pickhardt, J. Biernat, E. M. Mandelkow, P. Davies, U. Aebi, E. Mandelkow, Biochemistry 2006, 45, 6446-6457.
19. E. M. Sigurdsson, Curr. Alzheimer Res. 2009, 6, 446-450.
20. G. A. Jicha, R. Bowser, I. G. Kazam, P. Davies, J. Neurosci. Res. 1997, 48, 128-132.
21. M. Mercken, M. Vandermeeren, U. Lubke, J. Six, J. Boons, A. VandeVoorde, J. J. Martin, J. Gheuens, Acta Neuropathol. 1992, 84, 265-272.
22. G. Carmel, E. M. Mager, L. I. Binder, J. Kuret, J. Biol. Chem. 1996, 271, 32789-32795.
23. G. A. Jicha, B. Berenfeld, P. Davies, J. Neurosci. Res. 1999, 55, 713-723.
24. N. Ghoshal, F. Garcia-Sierra, Y. Fu, L. A. Beckett, E. J. Mufson, J. Kuret, R. W. Berry, L. I. Binder, J. Neurochem. 2001, 77, 1372-1385.
25. G. A. Jicha, R. Bowser, I. G. Kazam, P. Davies, J. Neurosci. Res. 1997, 48, 128-132.
26. A. deCalignon, L. M. Fox, R. Pitstick, G. A. Carlson, B. J. Bacskai, T. L. Spires-Jones, B. T. Hyman, Nature 2010, 464, 1201-1204.
27. C. L. Weaver, M. Espinoza, Y. Kress, P. Davies, Neurobiol. Aging 2000, 21, 719-727.
28. M. D. Mukrasch, S. Bibow, J. Korukottu, S. Jeganathan, J. Biernat, C. Griesinger, E. Mandelkow, M. Zweckstetter, PLoS Biol. 2009, 7, e 34.