The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis

Biochemistry

Volumn 45, Issue 20, 2006, Pages 6446-6457

  Von Bergen, Martin ^a   Barghorn, Stefan ^a,d   Müller, Shirley A ^b   Pickhardt, Marcus ^a   Biernat, Jacek ^a   Mandelkow, Eva Maria ^a   Davies, Peter ^c   Aebi, Ueli ^b   Mandelkow, Eckhard ^a  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

^b UNIVERSITY OF BASEL   (Switzerland)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^d ABBOTT GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DATA ACQUISITION; MATHEMATICAL MODELS; PROTEINS; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

PAIRED HELICAL FILAMENTS (PHF); PROTEOLYSIS; SCANNING TRANSMISSION ELECTRON MICROSCOPY (STEM);

DISEASE CONTROL;

MICROTUBULE ASSOCIATED PROTEIN; RECOMBINANT PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; BRAIN DISEASE; FLUORESCENCE SPECTROSCOPY; HUMAN; MASS SPECTROMETRY; NEUROLOGIC DISEASE; PAIRED HELICAL FILAMENT; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SENILE PLAQUE; TRANSMISSION ELECTRON MICROSCOPY;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; BRAIN; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON, SCANNING TRANSMISSION; MICROTUBULES; MODELS, BIOLOGICAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; NEUROFIBRILLARY TANGLES; PEPTIDE HYDROLASES; RECOMBINANT PROTEINS; TAU PROTEINS;

EID: 33646857025     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052530j     Document Type: Article

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