-
1
-
-
33847414390
-
A case of mistaken identity? Nonductal origins of pancreatic 'ductal' cancers.
-
Murtaugh LC, Leach SD. A case of mistaken identity? Nonductal origins of pancreatic 'ductal' cancers. Cancer Cell 2007, 11:211-213.
-
(2007)
Cancer Cell
, vol.11
, pp. 211-213
-
-
Murtaugh, L.C.1
Leach, S.D.2
-
2
-
-
0242348108
-
What is the origin of pancreatic adenocarcinoma?
-
Pour PM, Pandey KK, Batra SK. What is the origin of pancreatic adenocarcinoma? Mol Cancer 2003, 2:13.
-
(2003)
Mol Cancer
, vol.2
, pp. 13
-
-
Pour, P.M.1
Pandey, K.K.2
Batra, S.K.3
-
3
-
-
78650250772
-
Pancreatic endocrine tumors.
-
Oberg K. Pancreatic endocrine tumors. Semin Oncol 2010, 37:594-618.
-
(2010)
Semin Oncol
, vol.37
, pp. 594-618
-
-
Oberg, K.1
-
4
-
-
70350225535
-
Vertebrate endoderm development and organ formation.
-
Zorn AM, Wells JM. Vertebrate endoderm development and organ formation. Annu Rev Cell Dev Biol 2009, 25:221-251.
-
(2009)
Annu Rev Cell Dev Biol
, vol.25
, pp. 221-251
-
-
Zorn, A.M.1
Wells, J.M.2
-
5
-
-
2942542776
-
Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus.
-
Chen Y, Pan FC, Brandes N, Afelik S, Solter M, Pieler T. Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Dev Biol 2004, 271:144-160.
-
(2004)
Dev Biol
, vol.271
, pp. 144-160
-
-
Chen, Y.1
Pan, F.C.2
Brandes, N.3
Afelik, S.4
Solter, M.5
Pieler, T.6
-
6
-
-
0037162287
-
Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development.
-
Stafford D, Prince VE. Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development. Curr Biol 2002, 12:1215-1220.
-
(2002)
Curr Biol
, vol.12
, pp. 1215-1220
-
-
Stafford, D.1
Prince, V.E.2
-
7
-
-
23944453381
-
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice.
-
Martin M, Gallego-Llamas J, Ribes V, Kedinger M, Niederreither K, Chambon P, Dolle P, Gradwohl G. Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev Biol 2005, 284:399-411.
-
(2005)
Dev Biol
, vol.284
, pp. 399-411
-
-
Martin, M.1
Gallego-Llamas, J.2
Ribes, V.3
Kedinger, M.4
Niederreither, K.5
Chambon, P.6
Dolle, P.7
Gradwohl, G.8
-
8
-
-
0034093614
-
Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
-
Wells JM, Melton DA. Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development 2000, 127:1563-1572.
-
(2000)
Development
, vol.127
, pp. 1563-1572
-
-
Wells, J.M.1
Melton, D.A.2
-
9
-
-
29744461931
-
FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo.
-
Dessimoz J, Opoka R, Kordich JJ, Grapin-Botton A, Wells JM. FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo. Mech Dev 2006, 123:42-55.
-
(2006)
Mech Dev
, vol.123
, pp. 42-55
-
-
Dessimoz, J.1
Opoka, R.2
Kordich, J.J.3
Grapin-Botton, A.4
Wells, J.M.5
-
10
-
-
0030681247
-
Notochord to endoderm signaling is required for pancreas development.
-
Kim SK, Hebrok M, Melton DA. Notochord to endoderm signaling is required for pancreas development. Development 1997, 124:4243-4252.
-
(1997)
Development
, vol.124
, pp. 4243-4252
-
-
Kim, S.K.1
Hebrok, M.2
Melton, D.A.3
-
12
-
-
2642589990
-
Notochord repression of endodermal Sonic hedgehog permits pancreas development.
-
Hebrok M, Kim SK, Melton DA. Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev 1998, 12:1705-1713.
-
(1998)
Genes Dev
, vol.12
, pp. 1705-1713
-
-
Hebrok, M.1
Kim, S.K.2
Melton, D.A.3
-
13
-
-
67649995217
-
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors.
-
Wandzioch E, Zaret KS. Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science 2009, 324:1707-1710.
-
(2009)
Science
, vol.324
, pp. 1707-1710
-
-
Wandzioch, E.1
Zaret, K.S.2
-
14
-
-
33751251034
-
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
-
Bardeesy N, Cheng KH, Berger JH, Chu GC, Pahler J, Olson P, Hezel AF, Horner J, Lauwers GY, Hanahan D, et al. Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. Genes Dev 2006, 20:3130-3146.
-
(2006)
Genes Dev
, vol.20
, pp. 3130-3146
-
-
Bardeesy, N.1
Cheng, K.H.2
Berger, J.H.3
Chu, G.C.4
Pahler, J.5
Olson, P.6
Hezel, A.F.7
Horner, J.8
Lauwers, G.Y.9
Hanahan, D.10
-
15
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice.
-
Jonsson J, Carlsson L, Edlund T, Edlund H. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994, 371:606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
16
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence.
-
Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 1997, 15:106-110.
-
(1997)
Nat Genet
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
17
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.
-
Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996, 122:983-995.
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
Hogan, B.L.7
Wright, C.V.8
-
18
-
-
0031253820
-
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1.
-
Stoffers DA, Ferrer J, Clarke WL, Habener JF. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat Genet 1997, 17:138-139.
-
(1997)
Nat Genet
, vol.17
, pp. 138-139
-
-
Stoffers, D.A.1
Ferrer, J.2
Clarke, W.L.3
Habener, J.F.4
-
19
-
-
77950355686
-
A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiency.
-
Nicolino M, Claiborn KC, Senee V, Boland A, Stoffers DA, Julier C. A novel hypomorphic PDX1 mutation responsible for permanent neonatal diabetes with subclinical exocrine deficiency. Diabetes 2010, 59:733-740.
-
(2010)
Diabetes
, vol.59
, pp. 733-740
-
-
Nicolino, M.1
Claiborn, K.C.2
Senee, V.3
Boland, A.4
Stoffers, D.A.5
Julier, C.6
-
20
-
-
35349020015
-
An illustrated review of early pancreas development in the mouse.
-
Jorgensen MC, Ahnfelt-Ronne J, Hald J, Madsen OD, Serup P, Hecksher-Sorensen J. An illustrated review of early pancreas development in the mouse. Endocr Rev 2007, 28:685-705.
-
(2007)
Endocr Rev
, vol.28
, pp. 685-705
-
-
Jorgensen, M.C.1
Ahnfelt-Ronne, J.2
Hald, J.3
Madsen, O.D.4
Serup, P.5
Hecksher-Sorensen, J.6
-
21
-
-
40949099880
-
Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells.
-
Burlison JS, Long Q, Fujitani Y, Wright CV, Magnuson MA. Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells. Dev Biol 2008, 316:74-86.
-
(2008)
Dev Biol
, vol.316
, pp. 74-86
-
-
Burlison, J.S.1
Long, Q.2
Fujitani, Y.3
Wright, C.V.4
Magnuson, M.A.5
-
22
-
-
0028869514
-
Expression of murine STF-1, a putative insulin gene transcription factor, in β cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny.
-
Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G. Expression of murine STF-1, a putative insulin gene transcription factor, in β cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development 1995, 121:11-18.
-
(1995)
Development
, vol.121
, pp. 11-18
-
-
Guz, Y.1
Montminy, M.R.2
Stein, R.3
Leonard, J.4
Gamer, L.W.5
Wright, C.V.6
Teitelman, G.7
-
23
-
-
0030873949
-
Hepatocyte nuclear factor 3β is involved in pancreatic β-cell-specific transcription of the pdx-1 gene.
-
Wu KL, Gannon M, Peshavaria M, Offield MF, Henderson E, Ray M, Marks A, Gamer LW, Wright CV, Stein R. Hepatocyte nuclear factor 3β is involved in pancreatic β-cell-specific transcription of the pdx-1 gene. Mol Cell Biol 1997, 17:6002-6013.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6002-6013
-
-
Wu, K.L.1
Gannon, M.2
Peshavaria, M.3
Offield, M.F.4
Henderson, E.5
Ray, M.6
Marks, A.7
Gamer, L.W.8
Wright, C.V.9
Stein, R.10
-
24
-
-
30944438716
-
Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation.
-
Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV. Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev 2006, 20:253-266.
-
(2006)
Genes Dev
, vol.20
, pp. 253-266
-
-
Fujitani, Y.1
Fujitani, S.2
Boyer, D.F.3
Gannon, M.4
Kawaguchi, Y.5
Ray, M.6
Shiota, M.7
Stein, R.W.8
Magnuson, M.A.9
Wright, C.V.10
-
25
-
-
84860410786
-
Context-specific α-to-β cell reprogramming by forced Pdx1 expression.
-
Yang YP, Thorel F, Boyer DF, Herrera PL, Wright CV. Context-specific α-to-β cell reprogramming by forced Pdx1 expression. Genes Dev 2011, 25:1680-1685.
-
(2011)
Genes Dev
, vol.25
, pp. 1680-1685
-
-
Yang, Y.P.1
Thorel, F.2
Boyer, D.F.3
Herrera, P.L.4
Wright, C.V.5
-
26
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors.
-
Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, Wright CV. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 2002, 32:128-134.
-
(2002)
Nat Genet
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
Wright, C.V.6
-
27
-
-
0029737816
-
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.
-
Krapp A, Knofler M, Frutiger S, Hughes GJ, Hagenbuchle O, Wellauer PK. The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein. EMBO J 1996, 15:4317-4329.
-
(1996)
EMBO J
, vol.15
, pp. 4317-4329
-
-
Krapp, A.1
Knofler, M.2
Frutiger, S.3
Hughes, G.J.4
Hagenbuchle, O.5
Wellauer, P.K.6
-
28
-
-
0032417268
-
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas.
-
Krapp A, Knofler M, Ledermann B, Burki K, Berney C, Zoerkler N, Hagenbuchle O, Wellauer PK. The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev 1998, 12:3752-3763.
-
(1998)
Genes Dev
, vol.12
, pp. 3752-3763
-
-
Krapp, A.1
Knofler, M.2
Ledermann, B.3
Burki, K.4
Berney, C.5
Zoerkler, N.6
Hagenbuchle, O.7
Wellauer, P.K.8
-
29
-
-
58049204234
-
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
-
Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH. Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev 2008, 22:3435-3448.
-
(2008)
Genes Dev
, vol.22
, pp. 3435-3448
-
-
Gao, N.1
LeLay, J.2
Vatamaniuk, M.Z.3
Rieck, S.4
Friedman, J.R.5
Kaestner, K.H.6
-
30
-
-
33746903357
-
Definitive endoderm of the mouse embryo: formation, cell fates, and morphogenetic function.
-
Lewis SL, Tam PP. Definitive endoderm of the mouse embryo: formation, cell fates, and morphogenetic function. Dev Dyn 2006, 235:2315-2329.
-
(2006)
Dev Dyn
, vol.235
, pp. 2315-2329
-
-
Lewis, S.L.1
Tam, P.P.2
-
31
-
-
67650246360
-
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells.
-
Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM. Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell 2009, 17:62-74.
-
(2009)
Dev Cell
, vol.17
, pp. 62-74
-
-
Spence, J.R.1
Lange, A.W.2
Lin, S.C.3
Kaestner, K.H.4
Lowy, A.M.5
Kim, I.6
Whitsett, J.A.7
Wells, J.M.8
-
32
-
-
0346727348
-
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.
-
Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A. Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet 2004, 36:83-87.
-
(2004)
Nat Genet
, vol.36
, pp. 83-87
-
-
Sumazaki, R.1
Shiojiri, N.2
Isoyama, S.3
Masu, M.4
Keino-Masu, K.5
Osawa, M.6
Nakauchi, H.7
Kageyama, R.8
Matsui, A.9
-
33
-
-
33846910410
-
SOX9 is required for maintenance of the pancreatic progenitor cell pool.
-
Seymour PA, Freude KK, Tran MN, Mayes EE, Jensen J, Kist R, Scherer G, Sander M. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A 2007, 104:1865-1870.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1865-1870
-
-
Seymour, P.A.1
Freude, K.K.2
Tran, M.N.3
Mayes, E.E.4
Jensen, J.5
Kist, R.6
Scherer, G.7
Sander, M.8
-
34
-
-
53649102798
-
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation.
-
Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M. A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol 2008, 323:19-30.
-
(2008)
Dev Biol
, vol.323
, pp. 19-30
-
-
Seymour, P.A.1
Freude, K.K.2
Dubois, C.L.3
Shih, H.P.4
Patel, N.A.5
Sander, M.6
-
35
-
-
78651228289
-
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine.
-
Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 2011, 43:34-41.
-
(2011)
Nat Genet
, vol.43
, pp. 34-41
-
-
Furuyama, K.1
Kawaguchi, Y.2
Akiyama, H.3
Horiguchi, M.4
Kodama, S.5
Kuhara, T.6
Hosokawa, S.7
Elbahrawy, A.8
Soeda, T.9
Koizumi, M.10
-
36
-
-
79951539242
-
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.
-
Kopp JL, Dubois CL, Schaffer AE, Hao E, Shih HP, Seymour PA, Ma J, Sander M. Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development 2011, 138:653-665.
-
(2011)
Development
, vol.138
, pp. 653-665
-
-
Kopp, J.L.1
Dubois, C.L.2
Schaffer, A.E.3
Hao, E.4
Shih, H.P.5
Seymour, P.A.6
Ma, J.7
Sander, M.8
-
37
-
-
0035694459
-
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis.
-
Bhushan A, Itoh N, Kato S, Thiery JP, Czernichow P, Bellusci S, Scharfmann R. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 2001, 128:5109-5117.
-
(2001)
Development
, vol.128
, pp. 5109-5117
-
-
Bhushan, A.1
Itoh, N.2
Kato, S.3
Thiery, J.P.4
Czernichow, P.5
Bellusci, S.6
Scharfmann, R.7
-
38
-
-
0035476469
-
Dorsal pancreas agenesis in N-cadherin- deficient mice
-
Esni F, Johansson BR, Radice GL, Semb H. Dorsal pancreas agenesis in N-cadherin- deficient mice. Dev Biol 2001, 238:202-212.
-
(2001)
Dev Biol
, vol.238
, pp. 202-212
-
-
Esni, F.1
Johansson, B.R.2
Radice, G.L.3
Semb, H.4
-
39
-
-
0032860478
-
Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
-
Harrison KA, Thaler J, Pfaff SL, Gu H, Kehrl JH. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. Nat Genet 1999, 23:71-75.
-
(1999)
Nat Genet
, vol.23
, pp. 71-75
-
-
Harrison, K.A.1
Thaler, J.2
Pfaff, S.L.3
Gu, H.4
Kehrl, J.H.5
-
40
-
-
0032844643
-
Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9
-
Li H, Arber S, Jessell TM, Edlund H. Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nat Genet 1999, 23:67-70.
-
(1999)
Nat Genet
, vol.23
, pp. 67-70
-
-
Li, H.1
Arber, S.2
Jessell, T.M.3
Edlund, H.4
-
41
-
-
0031020002
-
Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells.
-
Ahlgren U, Pfaff SL, Jessell TM, Edlund T, Edlund H. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature 1997, 385:257-260.
-
(1997)
Nature
, vol.385
, pp. 257-260
-
-
Ahlgren, U.1
Pfaff, S.L.2
Jessell, T.M.3
Edlund, T.4
Edlund, H.5
-
42
-
-
33745214464
-
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas
-
Fukuda A, Kawaguchi Y, Furuyama K, Kodama S, Horiguchi M, Kuhara T, Koizumi M, Boyer DF, Fujimoto K, Doi R, et al. Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. J Clin Invest 2006, 116:1484-1493.
-
(2006)
J Clin Invest
, vol.116
, pp. 1484-1493
-
-
Fukuda, A.1
Kawaguchi, Y.2
Furuyama, K.3
Kodama, S.4
Horiguchi, M.5
Kuhara, T.6
Koizumi, M.7
Boyer, D.F.8
Fujimoto, K.9
Doi, R.10
-
43
-
-
1342263524
-
Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a.
-
Yoshitomi H, Zaret KS. Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development 2004, 131:807-817.
-
(2004)
Development
, vol.131
, pp. 807-817
-
-
Yoshitomi, H.1
Zaret, K.S.2
-
44
-
-
77957299842
-
Epithelial: endothelial cross-talk regulates exocrine differentiation in developing pancreas.
-
Pierreux CE, Cordi S, Hick AC, Achouri Y, Ruiz de Almodovar C, Prevot PP, Courtoy PJ, Carmeliet P, Lemaigre FP. Epithelial: endothelial cross-talk regulates exocrine differentiation in developing pancreas. Dev Biol 2010, 347:216-227.
-
(2010)
Dev Biol
, vol.347
, pp. 216-227
-
-
Pierreux, C.E.1
Cordi, S.2
Hick, A.C.3
Achouri, Y.4
Ruiz de Almodovar, C.5
Prevot, P.P.6
Courtoy, P.J.7
Carmeliet, P.8
Lemaigre, F.P.9
-
45
-
-
77955272726
-
'Giving and taking': endothelial and β-cells in the islets of Langerhans.
-
Eberhard D, Kragl M, Lammert E. 'Giving and taking': endothelial and β-cells in the islets of Langerhans. Trends Endocrinol Metab 2010, 21:457-463.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 457-463
-
-
Eberhard, D.1
Kragl, M.2
Lammert, E.3
-
46
-
-
78650219917
-
Epithelial dynamics of pancreatic branching morphogenesis.
-
Villasenor A, Chong DC, Henkemeyer M, Cleaver O. Epithelial dynamics of pancreatic branching morphogenesis. Development 2011, 137:4295-4305.
-
(2011)
Development
, vol.137
, pp. 4295-4305
-
-
Villasenor, A.1
Chong, D.C.2
Henkemeyer, M.3
Cleaver, O.4
-
47
-
-
0029793745
-
Cadherins regulate aggregation of pancreatic β-cells in vivo.
-
Dahl U, Sjodin A, Semb H. Cadherins regulate aggregation of pancreatic β-cells in vivo. Development 1996, 122:2895-2902.
-
(1996)
Development
, vol.122
, pp. 2895-2902
-
-
Dahl, U.1
Sjodin, A.2
Semb, H.3
-
48
-
-
59649089873
-
Rac1 regulates pancreatic islet morphogenesis.
-
Greiner TU, Kesavan G, Stahlberg A, Semb H. Rac1 regulates pancreatic islet morphogenesis. BMC Dev Biol 2009, 9:2.
-
(2009)
BMC Dev Biol
, vol.9
, pp. 2
-
-
Greiner, T.U.1
Kesavan, G.2
Stahlberg, A.3
Semb, H.4
-
49
-
-
77955978501
-
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.
-
Schaffer AE, Freude KK, Nelson SB, Sander M. Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev Cell 2010, 18:1022-1029.
-
(2010)
Dev Cell
, vol.18
, pp. 1022-1029
-
-
Schaffer, A.E.1
Freude, K.K.2
Nelson, S.B.3
Sander, M.4
-
50
-
-
76349104426
-
Notch signaling in pancreatic endocrine cell and diabetes.
-
Kim W, Shin YK, Kim BJ, Egan JM. Notch signaling in pancreatic endocrine cell and diabetes. Biochem Biophys Res Commun 2010, 392:247-251.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 247-251
-
-
Kim, W.1
Shin, Y.K.2
Kim, B.J.3
Egan, J.M.4
-
51
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1.
-
Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD. Control of endodermal endocrine development by Hes-1. Nat Genet 2000, 24:36-44.
-
(2000)
Nat Genet
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
Kageyama, R.7
Guillemot, F.8
Serup, P.9
Madsen, O.D.10
-
52
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation.
-
Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H. Notch signalling controls pancreatic cell differentiation. Nature 1999, 400:877-881.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe de Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
53
-
-
0344736673
-
Notch signaling controls multiple steps of pancreatic differentiation.
-
Murtaugh LC, Stanger BZ, Kwan KM, Melton DA. Notch signaling controls multiple steps of pancreatic differentiation. Proc Natl Acad Sci U S A 2003, 100:14920-14925.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14920-14925
-
-
Murtaugh, L.C.1
Stanger, B.Z.2
Kwan, K.M.3
Melton, D.A.4
-
56
-
-
0026321596
-
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene.
-
Herrera PL, Huarte J, Sanvito F, Meda P, Orci L, Vassalli JD. Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development 1991, 113:1257-1265.
-
(1991)
Development
, vol.113
, pp. 1257-1265
-
-
Herrera, P.L.1
Huarte, J.2
Sanvito, F.3
Meda, P.4
Orci, L.5
Vassalli, J.D.6
-
57
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.
-
Gradwohl G, Dierich A, LeMeur M, Guillemot F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 2000, 97:1607-1611.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
58
-
-
0037213351
-
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.
-
Gu G, Brown JR, Melton DA. Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis. Mech Dev 2003, 120:35-43.
-
(2003)
Mech Dev
, vol.120
, pp. 35-43
-
-
Gu, G.1
Brown, J.R.2
Melton, D.A.3
-
59
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
-
Gu G, Dubauskaite J, Melton DA. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002, 129:2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
60
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.
-
Johansson KA, Dursun U, Jordan N, Gu G, Beermann F, Gradwohl G, Grapin-Botton A. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell 2007, 12:457-465.
-
(2007)
Dev Cell
, vol.12
, pp. 457-465
-
-
Johansson, K.A.1
Dursun, U.2
Jordan, N.3
Gu, G.4
Beermann, F.5
Gradwohl, G.6
Grapin-Botton, A.7
-
61
-
-
77649182245
-
Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas.
-
Wang S, Yan J, Anderson DA, Xu Y, Kanal MC, Cao Z, Wright CV, Gu G. Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas. Dev Biol 2010, 339:26-37.
-
(2010)
Dev Biol
, vol.339
, pp. 26-37
-
-
Wang, S.1
Yan, J.2
Anderson, D.A.3
Xu, Y.4
Kanal, M.C.5
Cao, Z.6
Wright, C.V.7
Gu, G.8
-
62
-
-
79951590737
-
Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.
-
Gouzi M, Kim YH, Katsumoto K, Johansson K, Grapin-Botton A. Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development. Dev Dyn 2011, 240:589-604.
-
(2011)
Dev Dyn
, vol.240
, pp. 589-604
-
-
Gouzi, M.1
Kim, Y.H.2
Katsumoto, K.3
Johansson, K.4
Grapin-Botton, A.5
-
63
-
-
0037192799
-
Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion.
-
Brissova M, Shiota M, Nicholson WE, Gannon M, Knobel SM, Piston DW, Wright CV, Powers AC. Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion. J Biol Chem 2002, 277:11225-11232.
-
(2002)
J Biol Chem
, vol.277
, pp. 11225-11232
-
-
Brissova, M.1
Shiota, M.2
Nicholson, W.E.3
Gannon, M.4
Knobel, S.M.5
Piston, D.W.6
Wright, C.V.7
Powers, A.C.8
-
64
-
-
38949149704
-
Pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis.
-
Gannon M, Ables ET, Crawford L, Lowe D, Offield MF, Magnuson MA, Wright CV. Pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol 2008, 314:406-417.
-
(2008)
Dev Biol
, vol.314
, pp. 406-417
-
-
Gannon, M.1
Ables, E.T.2
Crawford, L.3
Lowe, D.4
Offield, M.F.5
Magnuson, M.A.6
Wright, C.V.7
-
65
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene.
-
Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 1993, 12:4251-4259.
-
(1993)
EMBO J
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
66
-
-
0030600549
-
Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription.
-
Watada H, Kajimoto Y, Kaneto H, Matsuoka T, Fujitani Y, Miyazaki J, Yamasaki Y. Involvement of the homeodomain-containing transcription factor PDX-1 in islet amyloid polypeptide gene transcription. Biochem Biophys Res Commun 1996, 229:746-751.
-
(1996)
Biochem Biophys Res Commun
, vol.229
, pp. 746-751
-
-
Watada, H.1
Kajimoto, Y.2
Kaneto, H.3
Matsuoka, T.4
Fujitani, Y.5
Miyazaki, J.6
Yamasaki, Y.7
-
67
-
-
29044449670
-
Endodermal expression of Nkx6 genes depends differentially on Pdx1.
-
Pedersen JK, Nelson SB, Jorgensen MC, Henseleit KD, Fujitani Y, Wright CV, Sander M, Serup P. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol 2005, 288:487-501.
-
(2005)
Dev Biol
, vol.288
, pp. 487-501
-
-
Pedersen, J.K.1
Nelson, S.B.2
Jorgensen, M.C.3
Henseleit, K.D.4
Fujitani, Y.5
Wright, C.V.6
Sander, M.7
Serup, P.8
-
68
-
-
0034524101
-
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of β-cell formation in the pancreas.
-
Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M. Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of β-cell formation in the pancreas. Development 2000, 127:5533-5540.
-
(2000)
Development
, vol.127
, pp. 5533-5540
-
-
Sander, M.1
Sussel, L.2
Conners, J.3
Scheel, D.4
Kalamaras, J.5
Dela Cruz, F.6
Schwitzgebel, V.7
Hayes-Jordan, A.8
German, M.9
-
69
-
-
34447521981
-
The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting β-cell fate specification in Pdx1+ pancreatic progenitor cells.
-
Nelson SB, Schaffer AE, Sander M. The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting β-cell fate specification in Pdx1+ pancreatic progenitor cells. Development 2007, 134:2491-2500.
-
(2007)
Development
, vol.134
, pp. 2491-2500
-
-
Nelson, S.B.1
Schaffer, A.E.2
Sander, M.3
-
70
-
-
23144437373
-
NKX6 transcription factor activity is required for α- and β-cell development in the pancreas.
-
Henseleit KD, Nelson SB, Kuhlbrodt K, Hennings JC, Ericson J, Sander M. NKX6 transcription factor activity is required for α- and β-cell development in the pancreas. Development 2005, 132:3139-3149.
-
(2005)
Development
, vol.132
, pp. 3139-3149
-
-
Henseleit, K.D.1
Nelson, S.B.2
Kuhlbrodt, K.3
Hennings, J.C.4
Ericson, J.5
Sander, M.6
-
71
-
-
0031843386
-
Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells.
-
Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells. Development 1998, 125:2213-2221.
-
(1998)
Development
, vol.125
, pp. 2213-2221
-
-
Sussel, L.1
Kalamaras, J.2
Hartigan-O'Connor, D.J.3
Meneses, J.J.4
Pedersen, R.A.5
Rubenstein, J.L.6
German, M.S.7
-
72
-
-
1542267814
-
Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development.
-
Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L. Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development. Proc Natl Acad Sci U S A 2004, 101:2924-2929.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2924-2929
-
-
Prado, C.L.1
Pugh-Bernard, A.E.2
Elghazi, L.3
Sosa-Pineda, B.4
Sussel, L.5
-
73
-
-
71449087141
-
Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (β2) by Nkx2.2 and neurogenin 3.
-
Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L. Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (β2) by Nkx2.2 and neurogenin 3. J Biol Chem 2009, 284:31236-31248.
-
(2009)
J Biol Chem
, vol.284
, pp. 31236-31248
-
-
Anderson, K.R.1
Torres, C.A.2
Solomon, K.3
Becker, T.C.4
Newgard, C.B.5
Wright, C.V.6
Hagman, J.7
Sussel, L.8
-
74
-
-
0030886674
-
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in β2/neuroD-deficient mice.
-
Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in β2/neuroD-deficient mice. Genes Dev 1997, 11:2323-2334.
-
(1997)
Genes Dev
, vol.11
, pp. 2323-2334
-
-
Naya, F.J.1
Huang, H.P.2
Qiu, Y.3
Mutoh, H.4
DeMayo, F.J.5
Leiter, A.B.6
Tsai, M.J.7
-
75
-
-
77950225021
-
Pancreatic β cells require NeuroD to achieve and maintain functional maturity.
-
Gu C, Stein GH, Pan N, Goebbels S, Hornberg H, Nave KA, Herrera P, White P, Kaestner KH, Sussel L, et al. Pancreatic β cells require NeuroD to achieve and maintain functional maturity. Cell Metab 2011, 11:298-310.
-
(2011)
Cell Metab
, vol.11
, pp. 298-310
-
-
Gu, C.1
Stein, G.H.2
Pan, N.3
Goebbels, S.4
Hornberg, H.5
Nave, K.A.6
Herrera, P.7
White, P.8
Kaestner, K.H.9
Sussel, L.10
-
76
-
-
0030897629
-
The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas.
-
Sosa-Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P. The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas. Nature 1997, 386:399-402.
-
(1997)
Nature
, vol.386
, pp. 399-402
-
-
Sosa-Pineda, B.1
Chowdhury, K.2
Torres, M.3
Oliver, G.4
Gruss, P.5
-
77
-
-
77956636575
-
Islet β-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.
-
Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, et al. Islet β-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain. Mol Cell Biol 2011, 30:4234-4244.
-
(2011)
Mol Cell Biol
, vol.30
, pp. 4234-4244
-
-
Raum, J.C.1
Hunter, C.S.2
Artner, I.3
Henderson, E.4
Guo, M.5
Elghazi, L.6
Sosa-Pineda, B.7
Ogihara, T.8
Mirmira, R.G.9
Sussel, L.10
-
78
-
-
1842330860
-
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.
-
Sander M, Neubuser A, Kalamaras J, Ee HC, Martin GR, German MS. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes Dev 1997, 11:1662-1673.
-
(1997)
Genes Dev
, vol.11
, pp. 1662-1673
-
-
Sander, M.1
Neubuser, A.2
Kalamaras, J.3
Ee, H.C.4
Martin, G.R.5
German, M.S.6
-
79
-
-
0030914931
-
Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas.
-
St-Onge L, Sosa-Pineda B, Chowdhury K, Mansouri A, Gruss P. Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas. Nature 1997, 387:406-409.
-
(1997)
Nature
, vol.387
, pp. 406-409
-
-
St-Onge, L.1
Sosa-Pineda, B.2
Chowdhury, K.3
Mansouri, A.4
Gruss, P.5
-
80
-
-
34247183601
-
MafB is required for islet β cell maturation.
-
Artner I, Blanchi B, Raum JC, Guo M, Kaneko T, Cordes S, Sieweke M, Stein R. MafB is required for islet β cell maturation. Proc Natl Acad Sci U S A 2007, 104:3853-3858.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 3853-3858
-
-
Artner, I.1
Blanchi, B.2
Raum, J.C.3
Guo, M.4
Kaneko, T.5
Cordes, S.6
Sieweke, M.7
Stein, R.8
-
81
-
-
20344368579
-
MafA is a key regulator of glucose-stimulated insulin secretion.
-
Zhang C, Moriguchi T, Kajihara M, Esaki R, Harada A, Shimohata H, Oishi H, Hamada M, Morito N, Hasegawa K, et al. MafA is a key regulator of glucose-stimulated insulin secretion. Mol Cell Biol 2005, 25:4969-4976.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4969-4976
-
-
Zhang, C.1
Moriguchi, T.2
Kajihara, M.3
Esaki, R.4
Harada, A.5
Shimohata, H.6
Oishi, H.7
Hamada, M.8
Morito, N.9
Hasegawa, K.10
-
82
-
-
15744393397
-
The islet β cell-enriched MafA activator is a key regulator of insulin gene transcription.
-
Zhao L, Guo M, Matsuoka TA, Hagman DK, Parazzoli SD, Poitout V, Stein R. The islet β cell-enriched MafA activator is a key regulator of insulin gene transcription. J Biol Chem 2005, 280:11887-11894.
-
(2005)
J Biol Chem
, vol.280
, pp. 11887-11894
-
-
Zhao, L.1
Guo, M.2
Matsuoka, T.A.3
Hagman, D.K.4
Parazzoli, S.D.5
Poitout, V.6
Stein, R.7
-
83
-
-
77957583357
-
MafA and MafB regulate genes critical to β-cells in a unique temporal manner.
-
Artner I, Hang Y, Mazur M, Yamamoto T, Guo M, Lindner J, Magnuson MA, Stein R. MafA and MafB regulate genes critical to β-cells in a unique temporal manner. Diabetes 2011, 59:2530-2539.
-
(2011)
Diabetes
, vol.59
, pp. 2530-2539
-
-
Artner, I.1
Hang, Y.2
Mazur, M.3
Yamamoto, T.4
Guo, M.5
Lindner, J.6
Magnuson, M.A.7
Stein, R.8
-
84
-
-
1542297749
-
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin.
-
Matsuoka TA, Artner I, Henderson E, Means A, Sander M, Stein R. The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proc Natl Acad Sci U S A 2004, 101:2930-2933.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2930-2933
-
-
Matsuoka, T.A.1
Artner, I.2
Henderson, E.3
Means, A.4
Sander, M.5
Stein, R.6
-
85
-
-
0031010659
-
Phenotypic alterations in insulin-deficient mutant mice.
-
Duvillie B, Cordonnier N, Deltour L, Dandoy-Dron F, Itier JM, Monthioux E, Jami J, Joshi RL, Bucchini D. Phenotypic alterations in insulin-deficient mutant mice. Proc Natl Acad Sci U S A 1997, 94:5137-5140.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 5137-5140
-
-
Duvillie, B.1
Cordonnier, N.2
Deltour, L.3
Dandoy-Dron, F.4
Itier, J.M.5
Monthioux, E.6
Jami, J.7
Joshi, R.L.8
Bucchini, D.9
-
86
-
-
0036214590
-
Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to β-cell hyperplasia in mutant mice lacking insulin.
-
Duvillie B, Currie C, Chrones T, Bucchini D, Jami J, Joshi RL, Hill DJ. Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to β-cell hyperplasia in mutant mice lacking insulin. Endocrinology 2002, 143:1530-1537.
-
(2002)
Endocrinology
, vol.143
, pp. 1530-1537
-
-
Duvillie, B.1
Currie, C.2
Chrones, T.3
Bucchini, D.4
Jami, J.5
Joshi, R.L.6
Hill, D.J.7
-
87
-
-
0142091542
-
Opposing actions of Arx and Pax4 in endocrine pancreas development.
-
Collombat P, Mansouri A, Hecksher-Sorensen J, Serup P, Krull J, Gradwohl G, Gruss P. Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev 2003, 17:2591-2603.
-
(2003)
Genes Dev
, vol.17
, pp. 2591-2603
-
-
Collombat, P.1
Mansouri, A.2
Hecksher-Sorensen, J.3
Serup, P.4
Krull, J.5
Gradwohl, G.6
Gruss, P.7
-
88
-
-
34147092649
-
Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression.
-
Collombat P, Hecksher-Sorensen J, Krull J, Berger J, Riedel D, Herrera PL, Serup P, Mansouri A. Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression. J Clin Invest 2007, 117:961-970.
-
(2007)
J Clin Invest
, vol.117
, pp. 961-970
-
-
Collombat, P.1
Hecksher-Sorensen, J.2
Krull, J.3
Berger, J.4
Riedel, D.5
Herrera, P.L.6
Serup, P.7
Mansouri, A.8
-
89
-
-
23144432613
-
The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the α- and β-cell lineages in the mouse endocrine pancreas.
-
Collombat P, Hecksher-Sorensen J, Broccoli V, Krull J, Ponte I, Mundiger T, Smith J, Gruss P, Serup P, Mansouri A. The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the α- and β-cell lineages in the mouse endocrine pancreas. Development 2005, 132:2969-2980.
-
(2005)
Development
, vol.132
, pp. 2969-2980
-
-
Collombat, P.1
Hecksher-Sorensen, J.2
Broccoli, V.3
Krull, J.4
Ponte, I.5
Mundiger, T.6
Smith, J.7
Gruss, P.8
Serup, P.9
Mansouri, A.10
-
90
-
-
80053580232
-
Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression.
-
Mastracci TL, Wilcox C, Panea C, Golden JA, May CL, Sussel L. Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol 2011, 359:1-11.
-
(2011)
Dev Biol
, vol.359
, pp. 1-11
-
-
Mastracci, T.L.1
Wilcox, C.2
Panea, C.3
Golden, J.A.4
May, C.L.5
Sussel, L.6
-
91
-
-
0030712878
-
POU domain transcription factor brain 4 confers pancreatic α-cell-specific expression of the proglucagon gene through interaction with a novel proximal promoter G1 element.
-
Hussain MA, Lee J, Miller CP, Habener JF. POU domain transcription factor brain 4 confers pancreatic α-cell-specific expression of the proglucagon gene through interaction with a novel proximal promoter G1 element. Mol Cell Biol 1997, 17:7186-7194.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 7186-7194
-
-
Hussain, M.A.1
Lee, J.2
Miller, C.P.3
Habener, J.F.4
-
92
-
-
0037013298
-
Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing β cells.
-
Hussain MA, Miller CP, Habener JF. Brn-4 transcription factor expression targeted to the early developing mouse pancreas induces ectopic glucagon gene expression in insulin-producing β cells. J Biol Chem 2002, 277:16028-16032.
-
(2002)
J Biol Chem
, vol.277
, pp. 16028-16032
-
-
Hussain, M.A.1
Miller, C.P.2
Habener, J.F.3
-
93
-
-
33750369213
-
The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice.
-
Petri A, Ahnfelt-Ronne J, Frederiksen KS, Edwards DG, Madsen D, Serup P, Fleckner J, Heller RS. The effect of neurogenin3 deficiency on pancreatic gene expression in embryonic mice. J Mol Endocrinol 2006, 37:301-316.
-
(2006)
J Mol Endocrinol
, vol.37
, pp. 301-316
-
-
Petri, A.1
Ahnfelt-Ronne, J.2
Frederiksen, K.S.3
Edwards, D.G.4
Madsen, D.5
Serup, P.6
Fleckner, J.7
Heller, R.S.8
-
94
-
-
0242412288
-
The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.
-
Lebel M, Agarwal P, Cheng CW, Kabir MG, Chan TY, Thanabalasingham V, Zhang X, Cohen DR, Husain M, Cheng SH, et al. The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice. Mol Cell Biol 2003, 23:8216-8225.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8216-8225
-
-
Lebel, M.1
Agarwal, P.2
Cheng, C.W.3
Kabir, M.G.4
Chan, T.Y.5
Thanabalasingham, V.6
Zhang, X.7
Cohen, D.R.8
Husain, M.9
Cheng, S.H.10
-
95
-
-
36549075522
-
Genetic identification of a novel NeuroD1 function in the early differentiation of islet α, PP and ε cells.
-
Chao CS, Loomis ZL, Lee JE, Sussel L. Genetic identification of a novel NeuroD1 function in the early differentiation of islet α, PP and ε cells. Dev Biol 2007, 312:523-532.
-
(2007)
Dev Biol
, vol.312
, pp. 523-532
-
-
Chao, C.S.1
Loomis, Z.L.2
Lee, J.E.3
Sussel, L.4
-
96
-
-
73249117478
-
Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet α-cells but not of intestinal L-cells.
-
Hayashi Y, Yamamoto M, Mizoguchi H, Watanabe C, Ito R, Yamamoto S, Sun XY, Murata Y. Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet α-cells but not of intestinal L-cells. Mol Endocrinol 2009, 23:1990-1999.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1990-1999
-
-
Hayashi, Y.1
Yamamoto, M.2
Mizoguchi, H.3
Watanabe, C.4
Ito, R.5
Yamamoto, S.6
Sun, X.Y.7
Murata, Y.8
-
97
-
-
0037098974
-
The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas.
-
Wierup N, Svensson H, Mulder H, Sundler F. The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas. Regul Pept 2002, 107:63-69.
-
(2002)
Regul Pept
, vol.107
, pp. 63-69
-
-
Wierup, N.1
Svensson, H.2
Mulder, H.3
Sundler, F.4
-
98
-
-
1242318803
-
Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells.
-
Wierup N, Yang S, McEvilly RJ, Mulder H, Sundler F. Ghrelin is expressed in a novel endocrine cell type in developing rat islets and inhibits insulin secretion from INS-1 (832/13) cells. J Histochem Cytochem 2004, 52:301-310.
-
(2004)
J Histochem Cytochem
, vol.52
, pp. 301-310
-
-
Wierup, N.1
Yang, S.2
McEvilly, R.J.3
Mulder, H.4
Sundler, F.5
-
99
-
-
25844456544
-
Genetic determinants of pancreatic ε-cell development.
-
Heller RS, Jenny M, Collombat P, Mansouri A, Tomasetto C, Madsen OD, Mellitzer G, Gradwohl G, Serup P. Genetic determinants of pancreatic ε-cell development. Dev Biol 2005, 286:217-224.
-
(2005)
Dev Biol
, vol.286
, pp. 217-224
-
-
Heller, R.S.1
Jenny, M.2
Collombat, P.3
Mansouri, A.4
Tomasetto, C.5
Madsen, O.D.6
Mellitzer, G.7
Gradwohl, G.8
Serup, P.9
-
100
-
-
68349083557
-
Ghrelin is dispensable for embryonic pancreatic islet development and differentiation.
-
Hill JT, Mastracci TL, Vinton C, Doyle ML, Anderson KR, Loomis ZL, Schrunk JM, Minic AD, Prabakar KR, Pugliese A, et al. Ghrelin is dispensable for embryonic pancreatic islet development and differentiation. Regul Pept 2009, 157:51-56.
-
(2009)
Regul Pept
, vol.157
, pp. 51-56
-
-
Hill, J.T.1
Mastracci, T.L.2
Vinton, C.3
Doyle, M.L.4
Anderson, K.R.5
Loomis, Z.L.6
Schrunk, J.M.7
Minic, A.D.8
Prabakar, K.R.9
Pugliese, A.10
-
101
-
-
0027308108
-
Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide.
-
Teitelman G, Alpert S, Polak JM, Martinez A, Hanahan D. Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide. Development 1993, 118:1031-1039.
-
(1993)
Development
, vol.118
, pp. 1031-1039
-
-
Teitelman, G.1
Alpert, S.2
Polak, J.M.3
Martinez, A.4
Hanahan, D.5
-
102
-
-
0028559916
-
Ablation of islet endocrine cells by targeted expression of hormone- promoter-driven toxigenes.
-
Herrera PL, Huarte J, Zufferey R, Nichols A, Mermillod B, Philippe J, Muniesa P, Sanvito F, Orci L, Vassalli JD. Ablation of islet endocrine cells by targeted expression of hormone- promoter-driven toxigenes. Proc Natl Acad Sci U S A 1994, 91:12999-13003.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 12999-13003
-
-
Herrera, P.L.1
Huarte, J.2
Zufferey, R.3
Nichols, A.4
Mermillod, B.5
Philippe, J.6
Muniesa, P.7
Sanvito, F.8
Orci, L.9
Vassalli, J.D.10
-
103
-
-
0034121735
-
Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages.
-
Herrera PL. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000, 127:2317-2322.
-
(2000)
Development
, vol.127
, pp. 2317-2322
-
-
Herrera, P.L.1
-
104
-
-
18144422810
-
Energy homeostasis and gastrointestinal endocrine differentiation do not require the anorectic hormone peptide YY.
-
Schonhoff S, Baggio L, Ratineau C, Ray SK, Lindner J, Magnuson MA, Drucker DJ, Leiter AB. Energy homeostasis and gastrointestinal endocrine differentiation do not require the anorectic hormone peptide YY. Mol Cell Biol 2005, 25:4189-4199.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 4189-4199
-
-
Schonhoff, S.1
Baggio, L.2
Ratineau, C.3
Ray, S.K.4
Lindner, J.5
Magnuson, M.A.6
Drucker, D.J.7
Leiter, A.B.8
-
105
-
-
63249127193
-
Somatostatin secreted by islet δ-cells fulfills multiple roles as a paracrine regulator of islet function.
-
Hauge-Evans AC, King AJ, Carmignac D, Richardson CC, Robinson IC, Low MJ, Christie MR, Persaud SJ, Jones PM. Somatostatin secreted by islet δ-cells fulfills multiple roles as a paracrine regulator of islet function. Diabetes 2009, 58:403-411.
-
(2009)
Diabetes
, vol.58
, pp. 403-411
-
-
Hauge-Evans, A.C.1
King, A.J.2
Carmignac, D.3
Richardson, C.C.4
Robinson, I.C.5
Low, M.J.6
Christie, M.R.7
Persaud, S.J.8
Jones, P.M.9
-
106
-
-
0034968209
-
Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth.
-
Low MJ, Otero-Corchon V, Parlow AF, Ramirez JL, Kumar U, Patel YC, Rubinstein M. Somatostatin is required for masculinization of growth hormone-regulated hepatic gene expression but not of somatic growth. J Clin Invest 2001, 107:1571-1580.
-
(2001)
J Clin Invest
, vol.107
, pp. 1571-1580
-
-
Low, M.J.1
Otero-Corchon, V.2
Parlow, A.F.3
Ramirez, J.L.4
Kumar, U.5
Patel, Y.C.6
Rubinstein, M.7
-
107
-
-
12944336527
-
Foxa2 is required for the differentiation of pancreatic alpha-cells
-
Lee CS, Sund NJ, Behr R, Herrera PL, Kaestner KH. Foxa2 is required for the differentiation of pancreatic alpha-cells. Dev Biol 2005, 278:484-495.
-
(2005)
Dev Biol
, vol.278
, pp. 484-495
-
-
Lee, C.S.1
Sund, N.J.2
Behr, R.3
Herrera, P.L.4
Kaestner, K.H.5
-
108
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies.
-
van Belle TL, Coppieters KT, von Herrath MG. Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev 2011, 91:79-118.
-
(2011)
Physiol Rev
, vol.91
, pp. 79-118
-
-
van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
109
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.
-
Fajans SS, Bell GI, Polonsky KS. Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 2001, 345:971-980.
-
(2001)
N Engl J Med
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
110
-
-
0026032055
-
Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q
-
Bell GI, Xiang KS, Newman MV, Wu SH, Wright LG, Fajans SS, Spielman RS, Cox NJ. Gene for non-insulin-dependent diabetes mellitus (maturity-onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci U S A 1991, 88:1484-1488.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 1484-1488
-
-
Bell, G.I.1
Xiang, K.S.2
Newman, M.V.3
Wu, S.H.4
Wright, L.G.5
Fajans, S.S.6
Spielman, R.S.7
Cox, N.J.8
-
111
-
-
9244258538
-
A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene
-
Stoffel M, Le Beau MM, Espinosa R, 3rd, Bohlander SF, Le Paslier D, Cohen D, Xiang KS, Cox NJ, Fajans SS, Bell GI. A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene. Proc Natl Acad Sci U S A 1996, 93:3937-3941.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 3937-3941
-
-
Stoffel, M.1
Le Beau, M.M.2
Espinosa, R.3
Bohlander, S.F.4
Le Paslier, D.5
Cohen, D.6
Xiang, K.S.7
Cox, N.J.8
Fajans, S.S.9
Bell, G.I.10
-
112
-
-
0026608764
-
Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
-
Froguel P, Vaxillaire M, Sun F, Velho G, Zouali H, Butel MO, Lesage S, Vionnet N, Clement K, Fougerousse F, et al. Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus. Nature 1992, 356:162-164.
-
(1992)
Nature
, vol.356
, pp. 162-164
-
-
Froguel, P.1
Vaxillaire, M.2
Sun, F.3
Velho, G.4
Zouali, H.5
Butel, M.O.6
Lesage, S.7
Vionnet, N.8
Clement, K.9
Fougerousse, F.10
-
113
-
-
0028907342
-
A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q
-
Vaxillaire M, Boccio V, Philippi A, Vigouroux C, Terwilliger J, Passa P, Beckmann JS, Velho G, Lathrop GM, Froguel P. A gene for maturity onset diabetes of the young (MODY) maps to chromosome 12q. Nat Genet 1995, 9:418-423.
-
(1995)
Nat Genet
, vol.9
, pp. 418-423
-
-
Vaxillaire, M.1
Boccio, V.2
Philippi, A.3
Vigouroux, C.4
Terwilliger, J.5
Passa, P.6
Beckmann, J.S.7
Velho, G.8
Lathrop, G.M.9
Froguel, P.10
-
114
-
-
0028848246
-
Localization of MODY3 to a 5-cM region of human chromosome 12
-
Menzel S, Yamagata K, Trabb JB, Nerup J, Permutt MA, Fajans SS, Menzel R, Iwasaki N, Omori Y, Cox NJ, et al. Localization of MODY3 to a 5-cM region of human chromosome 12. Diabetes 1995, 44:1408-1413.
-
(1995)
Diabetes
, vol.44
, pp. 1408-1413
-
-
Menzel, S.1
Yamagata, K.2
Trabb, J.B.3
Nerup, J.4
Permutt, M.A.5
Fajans, S.S.6
Menzel, R.7
Iwasaki, N.8
Omori, Y.9
Cox, N.J.10
-
115
-
-
0031453186
-
Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY
-
Horikawa Y, Iwasaki N, Hara M, Furuta H, Hinokio Y, Cockburn BN, Lindner T, Yamagata K, Ogata M, Tomonaga O, et al. Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nat Genet 1997, 17:384-385.
-
(1997)
Nat Genet
, vol.17
, pp. 384-385
-
-
Horikawa, Y.1
Iwasaki, N.2
Hara, M.3
Furuta, H.4
Hinokio, Y.5
Cockburn, B.N.6
Lindner, T.7
Yamagata, K.8
Ogata, M.9
Tomonaga, O.10
-
116
-
-
0032700272
-
Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus
-
Malecki MT, Jhala US, Antonellis A, Fields L, Doria A, Orban T, Saad M, Warram JH, Montminy M, Krolewski AS. Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus. Nat Genet 1999, 23:323-328.
-
(1999)
Nat Genet
, vol.23
, pp. 323-328
-
-
Malecki, M.T.1
Jhala, U.S.2
Antonellis, A.3
Fields, L.4
Doria, A.5
Orban, T.6
Saad, M.7
Warram, J.H.8
Montminy, M.9
Krolewski, A.S.10
-
117
-
-
20144389645
-
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function
-
Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V, Dina C, Hamid YH, Joly E, Vaillant E, Benmezroua Y, Durand E, Bakaher N, et al. Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proc Natl Acad Sci U S A 2005, 102:4807-4812.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4807-4812
-
-
Neve, B.1
Fernandez-Zapico, M.E.2
Ashkenazi-Katalan, V.3
Dina, C.4
Hamid, Y.H.5
Joly, E.6
Vaillant, E.7
Benmezroua, Y.8
Durand, E.9
Bakaher, N.10
-
118
-
-
29444440400
-
Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction
-
Raeder H, Johansson S, Holm PI, Haldorsen IS, Mas E, Sbarra V, Nermoen I, Eide SA, Grevle L, Bjorkhaug L, et al. Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. Nat Genet 2006, 38:54-62.
-
(2006)
Nat Genet
, vol.38
, pp. 54-62
-
-
Raeder, H.1
Johansson, S.2
Holm, P.I.3
Haldorsen, I.S.4
Mas, E.5
Sbarra, V.6
Nermoen, I.7
Eide, S.A.8
Grevle, L.9
Bjorkhaug, L.10
-
119
-
-
34447132254
-
PAX4 mutations in Thais with maturity onset diabetes of the young
-
Plengvidhya N, Kooptiwut S, Songtawee N, Doi A, Furuta H, Nishi M, Nanjo K, Tantibhedhyangkul W, Boonyasrisawat W, Yenchitsomanus PT, et al. PAX4 mutations in Thais with maturity onset diabetes of the young. J Clin Endocrinol Metab 2007, 92:2821-2826.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2821-2826
-
-
Plengvidhya, N.1
Kooptiwut, S.2
Songtawee, N.3
Doi, A.4
Furuta, H.5
Nishi, M.6
Nanjo, K.7
Tantibhedhyangkul, W.8
Boonyasrisawat, W.9
Yenchitsomanus, P.T.10
-
120
-
-
42449134450
-
Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood
-
Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, et al. Insulin mutation screening in 1, 044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood. Diabetes 2008, 57:1034-1042.
-
(2008)
Diabetes
, vol.57
, pp. 1034-1042
-
-
Edghill, E.L.1
Flanagan, S.E.2
Patch, A.M.3
Boustred, C.4
Parrish, A.5
Shields, B.6
Shepherd, M.H.7
Hussain, K.8
Kapoor, R.R.9
Malecki, M.10
-
121
-
-
42449127920
-
Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes
-
Molven A, Ringdal M, Nordbo AM, Raeder H, Stoy J, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, et al. Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes. Diabetes 2008, 57:1131-1135.
-
(2008)
Diabetes
, vol.57
, pp. 1131-1135
-
-
Molven, A.1
Ringdal, M.2
Nordbo, A.M.3
Raeder, H.4
Stoy, J.5
Lipkind, G.M.6
Steiner, D.F.7
Philipson, L.H.8
Bergmann, I.9
Aarskog, D.10
-
122
-
-
2342539735
-
Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23
-
Kim SH, Ma X, Weremowicz S, Ercolino T, Powers C, Mlynarski W, Bashan KA, Warram JH, Mychaleckyj J, Rich SS, et al. Identification of a locus for maturity-onset diabetes of the young on chromosome 8p23. Diabetes 2004, 53:1375-1384.
-
(2004)
Diabetes
, vol.53
, pp. 1375-1384
-
-
Kim, S.H.1
Ma, X.2
Weremowicz, S.3
Ercolino, T.4
Powers, C.5
Mlynarski, W.6
Bashan, K.A.7
Warram, J.H.8
Mychaleckyj, J.9
Rich, S.S.10
-
123
-
-
70149104834
-
Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction
-
Borowiec M, Liew CW, Thompson R, Boonyasrisawat W, Hu J, Mlynarski WM, El Khattabi I, Kim SH, Marselli L, Rich SS, et al. Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction. Proc Natl Acad Sci U S A 2009, 106:14460-14465.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14460-14465
-
-
Borowiec, M.1
Liew, C.W.2
Thompson, R.3
Boonyasrisawat, W.4
Hu, J.5
Mlynarski, W.M.6
El Khattabi, I.7
Kim, S.H.8
Marselli, L.9
Rich, S.S.10
-
124
-
-
33745268851
-
Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.
-
Senee V, Chelala C, Duchatelet S, Feng D, Blanc H, Cossec JC, Charon C, Nicolino M, Boileau P, Cavener DR, et al. Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism. Nat Genet 2006, 38:682-687.
-
(2006)
Nat Genet
, vol.38
, pp. 682-687
-
-
Senee, V.1
Chelala, C.2
Duchatelet, S.3
Feng, D.4
Blanc, H.5
Cossec, J.C.6
Charon, C.7
Nicolino, M.8
Boileau, P.9
Cavener, D.R.10
-
125
-
-
79551686759
-
Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes.
-
Pearl EJ, Jarikji Z, Horb ME. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev Biol 2011, 351:135-145.
-
(2011)
Dev Biol
, vol.351
, pp. 135-145
-
-
Pearl, E.J.1
Jarikji, Z.2
Horb, M.E.3
-
126
-
-
9644255692
-
Mutations in PTF1A cause pancreatic and cerebellar agenesis.
-
Sellick GS, Barker KT, Stolte-Dijkstra I, Fleischmann C, Coleman RJ, Garrett C, Gloyn AL, Edghill EL, Hattersley AT, Wellauer PK, et al. Mutations in PTF1A cause pancreatic and cerebellar agenesis. Nat Genet 2004, 36:1301-1305.
-
(2004)
Nat Genet
, vol.36
, pp. 1301-1305
-
-
Sellick, G.S.1
Barker, K.T.2
Stolte-Dijkstra, I.3
Fleischmann, C.4
Coleman, R.J.5
Garrett, C.6
Gloyn, A.L.7
Edghill, E.L.8
Hattersley, A.T.9
Wellauer, P.K.10
-
127
-
-
0034425698
-
EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome.
-
Delepine M, Nicolino M, Barrett T, Golamaully M, Lathrop GM, Julier C. EIF2AK3, encoding translation initiation factor 2-α kinase 3, is mutated in patients with Wolcott-Rallison syndrome. Nat Genet 2000, 25:406-409.
-
(2000)
Nat Genet
, vol.25
, pp. 406-409
-
-
Delepine, M.1
Nicolino, M.2
Barrett, T.3
Golamaully, M.4
Lathrop, G.M.5
Julier, C.6
-
128
-
-
35448994352
-
Insulin gene mutations as a cause of permanent neonatal diabetes.
-
Stoy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, et al. Insulin gene mutations as a cause of permanent neonatal diabetes. Proc Natl Acad Sci U S A 2007, 104:15040-15044.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 15040-15044
-
-
Stoy, J.1
Edghill, E.L.2
Flanagan, S.E.3
Ye, H.4
Paz, V.P.5
Pluzhnikov, A.6
Below, J.E.7
Hayes, M.G.8
Cox, N.J.9
Lipkind, G.M.10
-
129
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.
-
Wildin RS, Ramsdell F, Peake J, Faravelli F, Casanova JL, Buist N, Levy-Lahad E, Mazzella M, Goulet O, Perroni L, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001, 27:18-20.
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
Levy-Lahad, E.7
Mazzella, M.8
Goulet, O.9
Perroni, L.10
-
130
-
-
2342633204
-
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.
-
Gloyn AL, Pearson ER, Antcliff JF, Proks P, Bruining GJ, Slingerland AS, Howard N, Srinivasan S, Silva JM, Molnes J, et al. Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes. N Engl J Med 2004, 350:1838-1849.
-
(2004)
N Engl J Med
, vol.350
, pp. 1838-1849
-
-
Gloyn, A.L.1
Pearson, E.R.2
Antcliff, J.F.3
Proks, P.4
Bruining, G.J.5
Slingerland, A.S.6
Howard, N.7
Srinivasan, S.8
Silva, J.M.9
Molnes, J.10
-
131
-
-
27944464159
-
Resurrections in Toronto: the emergence of insulin.
-
Bliss M. Resurrections in Toronto: the emergence of insulin. Horm Res 2005, 64(suppl 2):98-102.
-
(2005)
Horm Res
, vol.64
, Issue.SUPPL. 2
, pp. 98-102
-
-
Bliss, M.1
-
132
-
-
0015040359
-
Paulesco and the isolation of insulin.
-
Murray I. Paulesco and the isolation of insulin. J Hist Med Allied Sci 1971, 26:150-157.
-
(1971)
J Hist Med Allied Sci
, vol.26
, pp. 150-157
-
-
Murray, I.1
-
133
-
-
79957589836
-
A recent survey confirms the efficacy and the safety of implanted insulin pumps during long-term use in poorly controlled type 1 diabetes patients.
-
Schaepelynck P, Renard E, Jeandidier N, Hanaire H, Fermon C, Rudoni S, Catargi B, Riveline JP, Guerci B, Millot L, et al. A recent survey confirms the efficacy and the safety of implanted insulin pumps during long-term use in poorly controlled type 1 diabetes patients. Diabetes Technol Ther 2011.
-
(2011)
Diabetes Technol Ther
-
-
Schaepelynck, P.1
Renard, E.2
Jeandidier, N.3
Hanaire, H.4
Fermon, C.5
Rudoni, S.6
Catargi, B.7
Riveline, J.P.8
Guerci, B.9
Millot, L.10
-
134
-
-
0034721255
-
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.
-
Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000, 343:230-238.
-
(2000)
N Engl J Med
, vol.343
, pp. 230-238
-
-
Shapiro, A.M.1
Lakey, J.R.2
Ryan, E.A.3
Korbutt, G.S.4
Toth, E.5
Warnock, G.L.6
Kneteman, N.M.7
Rajotte, R.V.8
-
135
-
-
21344462346
-
Five-year follow-up after clinical islet transplantation.
-
Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, Lakey JR, Shapiro AM. Five-year follow-up after clinical islet transplantation. Diabetes 2005, 54:2060-2069.
-
(2005)
Diabetes
, vol.54
, pp. 2060-2069
-
-
Ryan, E.A.1
Paty, B.W.2
Senior, P.A.3
Bigam, D.4
Alfadhli, E.5
Kneteman, N.M.6
Lakey, J.R.7
Shapiro, A.M.8
-
136
-
-
2342424743
-
Development of definitive endoderm from embryonic stem cells in culture.
-
Kubo A, Shinozaki K, Shannon JM, Kouskoff V, Kennedy M, Woo S, Fehling HJ, Keller G. Development of definitive endoderm from embryonic stem cells in culture. Development 2004, 131:1651-1662.
-
(2004)
Development
, vol.131
, pp. 1651-1662
-
-
Kubo, A.1
Shinozaki, K.2
Shannon, J.M.3
Kouskoff, V.4
Kennedy, M.5
Woo, S.6
Fehling, H.J.7
Keller, G.8
-
137
-
-
62949210744
-
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
-
Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 2009, 4:348-358.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 348-358
-
-
Borowiak, M.1
Maehr, R.2
Chen, S.3
Chen, A.E.4
Tang, W.5
Fox, J.L.6
Schreiber, S.L.7
Melton, D.A.8
-
138
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
139
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development.
-
Murry CE, Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 2008, 132:661-680.
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
140
-
-
0037047695
-
Differentiation of pluripotent embryonic stem cells into cardiomyocytes.
-
Boheler KR, Czyz J, Tweedie D, Yang HT, Anisimov SV, Wobus AM. Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res 2002, 91:189-201.
-
(2002)
Circ Res
, vol.91
, pp. 189-201
-
-
Boheler, K.R.1
Czyz, J.2
Tweedie, D.3
Yang, H.T.4
Anisimov, S.V.5
Wobus, A.M.6
-
141
-
-
0035845526
-
Hematopoietic colony-forming cells derived from human embryonic stem cells.
-
Kaufman DS, Hanson ET, Lewis RL, Auerbach R, Thomson JA. Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A 2001, 98:10716-10721.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 10716-10721
-
-
Kaufman, D.S.1
Hanson, E.T.2
Lewis, R.L.3
Auerbach, R.4
Thomson, J.A.5
-
142
-
-
0034101804
-
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.
-
Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat Biotechnol 2000, 18:399-404.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 399-404
-
-
Reubinoff, B.E.1
Pera, M.F.2
Fong, C.Y.3
Trounson, A.4
Bongso, A.5
-
143
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to β-cells.
-
Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature 2008, 455:627-632.
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
144
-
-
77951611220
-
Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss.
-
Thorel F, Nepote V, Avril I, Kohno K, Desgraz R, Chera S, Herrera PL. Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss. Nature 2010, 464:1149-1154.
-
(2010)
Nature
, vol.464
, pp. 1149-1154
-
-
Thorel, F.1
Nepote, V.2
Avril, I.3
Kohno, K.4
Desgraz, R.5
Chera, S.6
Herrera, P.L.7
-
145
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.
-
D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, Moorman MA, Kroon E, Carpenter MK, Baetge EE. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006, 24: 1392-1401.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
Kelly, O.G.4
Agulnick, A.D.5
Smart, N.G.6
Moorman, M.A.7
Kroon, E.8
Carpenter, M.K.9
Baetge, E.E.10
-
146
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm.
-
D'Amour KA, Agulnick AD, Eliazer S, Kelly OG, Kroon E, Baetge EE. Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 2005, 23:1534-1541.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
-
147
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo.
-
Kroon E, Martinson LA, Kadoya K, Bang AG, Kelly OG, Eliazer S, Young H, Richardson M, Smart NG, Cunningham J, et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol 2008, 26:443-452.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
Young, H.7
Richardson, M.8
Smart, N.G.9
Cunningham, J.10
-
148
-
-
79551580013
-
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.
-
Nostro MC, Sarangi F, Ogawa S, Holtzinger A, Corneo B, Li X, Micallef SJ, Park IH, Basford C, Wheeler MB, et al. Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development 2011, 138:861-871.
-
(2011)
Development
, vol.138
, pp. 861-871
-
-
Nostro, M.C.1
Sarangi, F.2
Ogawa, S.3
Holtzinger, A.4
Corneo, B.5
Li, X.6
Micallef, S.J.7
Park, I.H.8
Basford, C.9
Wheeler, M.B.10
-
149
-
-
79951648873
-
Pancreas organogenesis: from bud to plexus to gland.
-
Pan FC, Wright C. Pancreas organogenesis: from bud to plexus to gland. Dev Dyn 2011, 240:530-565.
-
(2011)
Dev Dyn
, vol.240
, pp. 530-565
-
-
Pan, F.C.1
Wright, C.2
-
150
-
-
76349104426
-
Notch signaling in pancreatic endocrine cell and diabetes.
-
Kim W, Shin YK, Kim BJ, Egan JM. Notch signaling in pancreatic endocrine cell and diabetes. Biochem Biophys Res Commun 2010, 392:247-251.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 247-251
-
-
Kim, W.1
Shin, Y.K.2
Kim, B.J.3
Egan, J.M.4
-
152
-
-
58549093915
-
Developmental biology of the pancreas: a comprehensive review.
-
Gittes GK. Developmental biology of the pancreas: a comprehensive review. Dev Biol 2009, 326:4-35.
-
(2009)
Dev Biol
, vol.326
, pp. 4-35
-
-
Gittes, G.K.1
-
153
-
-
35349020015
-
An illustrated review of early pancreas development in the mouse.
-
Jorgensen MC, Ahnfelt-Ronne J, Hald J, Madsen OD, Serup P, Hecksher-Sorensen J. An illustrated review of early pancreas development in the mouse. Endocr Rev 2007, 28:685-705.
-
(2007)
Endocr Rev
, vol.28
, pp. 685-705
-
-
Jorgensen, M.C.1
Ahnfelt-Ronne, J.2
Hald, J.3
Madsen, O.D.4
Serup, P.5
Hecksher-Sorensen, J.6
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