Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation

Journal of Biological Chemistry

Volumn 288, Issue 5, 2013, Pages 3208-3218

  Sathanoori, Ramasri ^a   Olde, Björn ^a   Erlinge, David ^a   Göransson, Olga ^a   Wierup, Nils ^b  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CELL; CELL SURVIVAL; CHROMATIN CONDENSATION; DATA POINTS; DNA FRAGMENTATION; GLUCOSE-STIMULATED INSULIN SECRETIONS; INSULIN SECRETION; NEURONAL SURVIVAL; RAT ISLETS; SIGNALING MECHANISMS; THERAPEUTIC INTERVENTION;

CELL PROLIFERATION; CELLS; GLUCOSE; INSULIN; PHOSPHORYLATION; PHYSIOLOGY; RATS;

CYTOLOGY;

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE[55-102]; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA; GLUCOSE; INSULIN RECEPTOR SUBSTRATE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; PROTEIN P90; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DNA FRAGMENTATION; FEMALE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL DEATH; CELL PROLIFERATION; CLONE CELLS; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOPROTECTION; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE; INSULIN-SECRETING CELLS; INTRACELLULAR SPACE; MITOGEN-ACTIVATED PROTEIN KINASE 3; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PHOSPHOSERINE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84873320832     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.437145     Document Type: Article

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