Regulation of cocaine- and amphetamine-regulated transcript mRNA expression by calcium-mediated signaling in GH3 cells

Neuroscience

Volumn 160, Issue 2, 2009, Pages 339-347

  Jones, D C ^a   Lakatos, A ^b   Rogge, G A ^a   Kuhar, M J ^a  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cart; cell signaling; CREB; gene regulation; ionomycin; neuropeptide

Indexed keywords

CALCIUM; CALMIDAZOLIUM; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IONOMYCIN; MESSENGER RNA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL STRAIN GH3; COMPLEX FORMATION; CONTROLLED STUDY; GENE CONTROL; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION; INTRACELLULAR FLUID; NERVE TISSUE PROTEINS; PITUITARY GLAND; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 64049105336     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.02.051     Document Type: Article

References (60)

1. Ahima R.S., and Hileman S.M. Postnatal regulation of hypothalamic neuropeptide expression by leptin: implications for energy balance and body weight regulation. Regul Pept 92 (2000) 1-7
2. Anderson K.A., Ribar T.J., Lin F., Noeldner P.K., Green M.F., Muehlbauer M.J., Witters L.A., Kemp B.E., and Means A.R. Hypothalamic CaMKK2 contributes to the regulation of energy balance. Cell Metab 7 (2008) 377-388
3. Barrett P., Davidson J., Morgan P., Morris M.A., Moar K.M., Mercer J.G., Davidson J.A., Findlay P.A., Adam C.L., and Morgan P.J. CART gene promoter transcription is regulated by a cyclic adenosine monophosphate response element-the differential regulation of CART gene expression in a pituitary cell line and primary cell cultures of ovine pars tuberalis cells. Obes Rev 10 (2002) 1291-1298
4. Barrett P., Morris M.A., Moar K.M., Mercer J.G., Davidson J.A., Findlay P.A., Adam C.L., and Morgan P.J. The differential regulation of CART gene expression in a pituitary cell line and primary cell cultures of ovine pars tuberalis cells. J Neuroendocrinol 13 (2001) 347-352
5. Beaudry G., Zekki H., Rouillard C., and Levesque D. Clozapine and dopamine D3 receptor antisense reduce cocaine- and amphetamine-regulated transcript expression in the rat nucleus accumbens shell. Synapse 51 (2004) 233-240
6. Boone E.M., Hawks B.W., Li W., and Garlow S.J. Genetic regulation of hypothalamic cocaine and amphetamine-regulated transcript (CART) in BxD inbred mice. Brain Res 1194 (2008) 1-7
7. Brenz Verca M.S., Widmer D.A., Wagner G.C., and Dreyer J. Cocaine-induced expression of the tetraspanin CD81 and its relation to hypothalamic function. Mol Cell Neurosci 17 (2001) 303-316
8. Carlezon Jr. W.A., Duman R.S., and Nestler E.J. The many faces of CREB. Trends Neurosci 28 (2005) 436-445
9. 2+-regulated transcriptional repressor. Nature 398 (1999) 80-84
10. 2+/CaM-dependent protein kinase cascade in health and disease. Subcell Biochem 45 (2007) 169-214
11. Dominguez G. The CART gene: structure and regulation. Peptides 27 (2006) 1913-1918
12. Dominguez G., and Kuhar M.J. Transcriptional regulation of the CART promoter in CATH a cells. Brain Res Mol Brain Res 126 (2004) 22-29
13. Dominguez G., Lakatos A., and Kuhar M.J. Characterization of the cocaine- and amphetamine-regulated transcript (CART) peptide gene promoter and its activation by a cyclic AMP-dependent signaling pathway in GH3 cells. J Neurochem 80 (2002) 885-893
14. Douglass J., McKinzie A.A., and Couceyro P. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J Neurosci 15 (1995) 2471-2481
15. Du C., Yu M., Volkow N.D., Koretsky A.P., Fowler J.S., and Benveniste H. Cocaine increases the intracellular calcium concentration in brain independently of its cerebrovascular effects. J Neurosci 26 (2006) 11522-11531
16. Gil-Parrado S., Fernandez-Montalvan A., Assfalg-Machleidt I., Popp O., Bestvater F., Holloschi A., Knoch T.A., Auerswald E.A., Welsh K., Reed J.C., Fritz H., Fuentes-Prior P., Spiess E., Salvesen G.S., and Machleidt W. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem 277 (2002) 27217-27226
17. Henning R.J., and Cuevas J. Cocaine activates calcium/calmodulin kinase II and causes cardiomyocyte hypertrophy. J Cardiovasc Pharmacol 48 (2006) 802-813
18. Hubert G.W., and Kuhar M.J. Cocaine administration increases the fraction of CART cells in the rat nucleus accumbens that co-immunostain for c-Fos. Neuropeptides 42 (2008) 339-343
19. Hunter R.G., Bellani R., Bloss E., Costa A., Romeo R.D., and McEwen B.S. Regulation of CART mRNA by stress and corticosteroids in the hippocampus and amygdala. Brain Res 1152 (2007) 234-240
20. Hunter R.G., Jones D., Vicentic A., Hue G., Rye D., and Kuhar M.J. Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors. Neuropharmacology 50 (2006) 858-864
21. Jean A., Conductier G., Manrique C., Bouras C., Berta P., Hen R., Charnay Y., Bockaert J., and Compan V. Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens. Proc Natl Acad Sci U S A 104 (2007) 16335-16340
22. Johansen J.E., Broberger C., Lavebratt C., Johansson C., Kuhar M.J., Hokfelt T., and Schalling M. Hypothalamic CART and serum leptin levels are reduced in the anorectic (anx/anx) mouse. Brain Res Mol Brain Res 84 (2000) 97-105
23. Jones D.C., and Kuhar M.J. Cocaine-amphetamine-regulated transcript expression in the rat nucleus accumbens is regulated by adenylyl cyclase and the cyclic adenosine 5′-monophosphate/protein kinase A second messenger system. J Pharmacol Exp Ther 317 (2006) 454-461
24. Kristensen P., Judge M.E., Thim L., Ribel U., Christjansen K.N., Wulff B.S., Clausen J.T., Jensen P.B., Madsen O.D., Vrang N., Larsen P.J., and Hastrup S. Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393 (1998) 72-76
25. Lakatos A., Dominguez G., and Kuhar M.J. CART promoter CRE site binds phosphorylated CREB. Brain Res Mol Brain Res 104 (2002) 81-85
26. Lambert P., Couceyro P., Koylu E., Ling N., DeSouza E., and Kuhar M. A role for novel CART peptide fragments in the central control of food intake. Neuropeptides 31 (1997) 620-621
27. Licata S.C., and Pierce R.C. The roles of calcium/calmodulin-dependent and ras/mitogen-activated protein kinases in the development of psychostimulant-induced behavioral sensitization. J Neurochem 85 (2003) 14-22
28. Licata S.C., Schmidt H.D., and Pierce R.C. Suppressing calcium/calmodulin-dependent protein kinase II activity in the ventral tegmental area enhances the acute behavioural response to cocaine but attenuates the initiation of cocaine-induced behavioural sensitization in rats. Eur J Neurosci 19 (2004) 405-414
29. Liu D., Genetos D.C., Shao Y., Geist D.J., Li J., Ke H.Z., Turner C.H., and Duncan R.L. Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)-and ATP-dependent in MC3T3-E1 osteoblasts. Bone 42 (2008) 644-652
30. Marie-Claire C., Laurendeau I., Canestrelli C., Courtin C., Vidaud M., Roques B., and Noble F. Fos but not cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain. Neurosci Lett 345 (2003) 77-80
31. Mattson B.J., Bossert J.M., Simmons D.E., Nozaki N., Nagarkar D., Kreuter J.D., and Hope B.T. Cocaine-induced CREB phosphorylation in nucleus accumbens of cocaine-sensitized rats is enabled by enhanced activation of extracellular signal-related kinase, but not protein kinase A. J Neurochem 95 (2005) 1481-1494
32. McCollum A.T., Jafarifar F., Chan R., and Guttmann R.P. Oxidative stress inhibits ionomycin-mediated cell death in cortical neurons. J Neurosci Res 76 (2004) 104-109
33. Mills K., Ansah T.A., Ali S.F., Mukherjee S., and Shockley D.C. Augmented behavioral response and enhanced synaptosomal calcium transport induced by repeated cocaine administration are decreased by calcium channel blockers. Life Sci 81 (2007) 600-608
34. 2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membrane. Biochem J 300 Pt 3 (1994) 665-672
35. th edition (1998), Academic Press, New York
36. Rajadhyaksha A.M., and Kosofsky B.E. Psychostimulants, L-type calcium channels, kinases, and phosphatases. Neuroscientist 11 (2005) 494-502
37. Rajadhyaksha A.M., and Kosofsky B.E. Psychostimulants, protein phosphorylation and gene expression: a growing role of L-type calcium channels. Cell Sci 2 (2005) 127-144
38. Rogge G., Jones D., Hubert G.W., Lin Y., and Kuhar M.J. CART peptides: regulators of body weight, reward and other functions. Nat Rev Neurosci 9 (2008) 747-758
39. Rogge G.A., Jones D.C., Green T., Nestler E., and Kuhar M.J. Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo. Brain Res 1251 (2009) 42-52
40. Salinas A., Wilde J.D., and Maldve R.E. Ethanol enhancement of cocaine- and amphetamine-regulated transcript mRNA and peptide expression in the nucleus accumbens. J Neurochem (2006) in press
41. Sen A., Bettegowda A., Jimenez-Krassel F., Ireland J.J., and Smith G.W. Cocaine- and amphetamine-regulated transcript regulation of follicle-stimulating hormone signal transduction in bovine granulosa cells. Endocrinology 148 (2007) 4400-4410
42. Shaywitz A.J., and Greenberg M.E. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68 (1999) 821-861
43. Shinnick-Gallagher P., McKernan M.G., Xie J., and Zinebi F. L-type voltage-gated calcium channels are involved in the in vivo and in vitro expression of fear conditioning. Ann N Y Acad Sci 985 (2003) 135-149
44. 2+ entry preferentially effects protein dephosphorylation, phosphorylation, and glutamate release. J Biol Chem 267 (1992) 1983-1989
45. 2+-stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning. Neuron 53 (2007) 79-89
46. Stanley S.A., Murphy K.G., Bewick G.A., Kong W.M., Opacka-Juffry J., Gardiner J.V., Ghatei M., Small C.J., and Bloom S.R. Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids. Am J Physiol Endocrinol Metab 287 (2004) E583-E590
47. Taruno A., Niisato N., and Marunaka Y. Intracellular calcium plays a role as the second messenger of hypotonic stress in gene regulation of SGK1 and ENaC in renal epithelial A6 cells. Am J Physiol Ren Physiol 294 (2008) F177-F186
48. Vicentic A., Hunter R.G., and Kuhar M.J. Effect of corticosterone on CART peptide levels in rat blood. Peptides 26 (2005) 531-533
49. Vicentic A., Lakatos A., Hunter R., Philpot K., Dominguez G., and Kuhar M.J. CART peptide diurnal rhythm in brain and effect of fasting. Brain Res 1032 (2005) 111-115
50. Vicentic A., and Jones D.C. The CART (cocaine- and amphetamine-regulated transcript) system in appetite and drug addiction. J Pharmacol Exp Ther 320 (2007) 499-506
51. Vrang N., Larsen P.J., and Kristensen P. Cocaine-amphetamine regulated transcript (CART) expression is not regulated by amphetamine. Neuroreport 13 (2002) 1215-1218
52. Wang J.H., Wang F., Yang M.J., Yu D.F., Wu W.N., Liu J., Ma L.Q., Cai F., and Chen J.G. Leptin regulated calcium channels of neuropeptide Y and proopiomelanocortin neurons by activation of different signal pathways. Neuroscience (2008) in press
53. West A.E., Chen W.G., Dalva M.B., Dolmetsch R.E., Kornhauser J.M., Shaywitz A.J., Takasu M.A., Tao X., and Greenberg M.E. Calcium regulation of neuronal gene expression. Proc Natl Acad Sci U S A 98 (2001) 11024-11031
54. Wortley K.E., Chang G.Q., Davydova Z., Fried S.K., and Leibowitz S.F. Cocaine- and amphetamine-regulated transcript in the arcuate nucleus stimulates lipid metabolism to control body fat accrual on a high-fat diet. Regul Pept 117 (2004) 89-99
55. 2+ and AMPK both mediate stimulation of glucose transport by muscle contractions. Diabetes 53 (2004) 330-335
56. Yang S.C., Shieh K.R., and Li H.Y. Cocaine- and amphetamine-regulated transcript in the nucleus accumbens participates in the regulation of feeding behavior in rats. Neuroscience 133 (2005) 841-851
57. 2+ signaling in hippocampal neurons. J Neurosci 21 (2001) 7474-7480
58. Yoshinaga N., Yasuda Y., Murayama T., and Nomura Y. Possible involvement of cytosolic phospholipase A(2) in cell death induced by 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in GH3 cells. Brain Res 855 (2000) 244-251
59. 2+ signals and growth hormone secretion. J Neuroendocrinol 16 (2004) 684-694
60. Zhang X.F., Cooper D.C., and White F.J. Repeated cocaine treatment decreases whole-cell calcium current in rat nucleus accumbens neurons. J Pharmacol Exp Ther 301 (2002) 1119-1125