-
1
-
-
0344258475
-
Impaired β-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose
-
DOI 10.2337/diabetes.48.6.1230
-
Marshak S., Leibowitz G., and Bertuzzi F. Impaired beta-cell functions induced by chronic exposure of cultured human pancreatic islets to high glucose Diabetes 48 1999 1230 1236 (Pubitemid 29241019)
-
(1999)
Diabetes
, vol.48
, Issue.6
, pp. 1230-1236
-
-
Marshak, S.1
Leibowitz, G.2
Bertuzzi, F.3
Socci, C.4
Kaiser, N.5
Gross, D.J.6
Cerasi, E.7
Melloul, D.8
-
2
-
-
0033034807
-
Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
-
Donath M., Gross D., and Cerasi E. Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes Diabetes 48 1999 738 744 (Pubitemid 29153072)
-
(1999)
Diabetes
, vol.48
, Issue.4
, pp. 738-744
-
-
Donath, M.Y.1
Gross, D.J.2
Cerasi, E.3
Kaiser, N.4
-
3
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
Maedler K., Sergeev P., and Ris F. Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets J Clin Invest 110 2002 851 860
-
(2002)
J Clin Invest
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
-
4
-
-
0034982387
-
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: A potential role for regulation of specific Bcl family genes toward an apoptotic cell death program
-
Federici M., Hribal M., and Perego L. High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell death program Diabetes 50 2001 1290 1301 (Pubitemid 32500161)
-
(2001)
Diabetes
, vol.50
, Issue.6
, pp. 1290-1301
-
-
Federici, M.1
Hribal, M.2
Perego, L.3
Ranalli, M.4
Caradonna, Z.5
Perego, C.6
Usellini, L.7
Nano, R.8
Bonini, P.9
Bertuzzi, F.10
Marlier, L.N.J.L.11
Davalli, A.M.12
Carandente, O.13
Pontiroli, A.E.14
Melino, G.15
Marchetti, P.16
Lauro, R.17
Sesti, G.18
Folli, F.19
-
5
-
-
0036315888
-
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: Evidence that β-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
-
Lupi R., Dotta F., and Marselli L. Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated Diabetes 51 2002 1437 1442 (Pubitemid 34826609)
-
(2002)
Diabetes
, vol.51
, Issue.5
, pp. 1437-1442
-
-
Lupi, R.1
Dotta, F.2
Marselli, L.3
Del Guerra, S.4
Masini, M.5
Santangelo, C.6
Patane, G.7
Boggi, U.8
Piro, S.9
Anello, M.10
Bergamini, E.11
Mosca, F.12
Di Mario, U.13
Del Prato, S.14
Marchetti, P.15
-
7
-
-
0035145780
-
Lipotoxicity of the pancreatic β-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids
-
Briaud I., Harmon J., and Kelpe C. Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids Diabetes 50 2001 315 321 (Pubitemid 32127288)
-
(2001)
Diabetes
, vol.50
, Issue.2
, pp. 315-321
-
-
Briaud, I.1
Harmon, J.S.2
Kelpe, C.L.3
Segu, V.B.G.4
Poitout, V.5
-
8
-
-
0030029605
-
Are the β-cell signaling molecules malonyl-CoA and cytosolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?
-
Prentki M., and Corkey B.E. Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM? Diabetes 45 1996 273 283 (Pubitemid 26069039)
-
(1996)
Diabetes
, vol.45
, Issue.3
, pp. 273-283
-
-
Prentki, M.1
Corkey, B.E.2
-
9
-
-
0036896505
-
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: Role in beta-cell adaptation and failure in the etiology of diabetes
-
Prentki M., Joly E., and El-Assaad W. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes Diabetes 51 2002 S405 S413
-
(2002)
Diabetes
, vol.51
-
-
Prentki, M.1
Joly, E.2
El-Assaad, W.3
-
10
-
-
43549108142
-
Glucolipotoxicity: Fuel excess and β-cell dysfunction
-
DOI 10.1210/er.2007-0023
-
Poitout V., and Robertson R.P. Glucolipotoxicity: fuel excess and beta-cell dysfunction Endocr Rev 29 2008 351 366 (Pubitemid 351679704)
-
(2008)
Endocrine Reviews
, vol.29
, Issue.3
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
11
-
-
1542374750
-
Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets
-
DOI 10.1007/s00125-003-1295-1
-
Lau T., Carlsson P., and Leung P. Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets Diabetologia 47 2004 240 248 (Pubitemid 38315360)
-
(2004)
Diabetologia
, vol.47
, Issue.2
, pp. 240-248
-
-
Lau, T.1
Carlsson, P.-O.2
Leung, P.S.3
-
12
-
-
33845538684
-
Angiotensin II and inflammation: The effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade
-
DOI 10.1038/sj.jhh.1002101, PII 1002101
-
Dandona P., Dhindsa S., and Ghanim H. Angiotensin II and inflammation: the effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockade J Hum Hypertens 21 2007 20 27 (Pubitemid 44921816)
-
(2007)
Journal of Human Hypertension
, vol.21
, Issue.1
, pp. 20-27
-
-
Dandona, P.1
Dhindsa, S.2
Ghanim, H.3
Chaudhuri, A.4
-
13
-
-
33644781780
-
Angiotensin II type 1 receptor blockade improves β-cell function and glucose tolerance in a mouse model of type 2 diabetes
-
DOI 10.2337/diabetes.55.02.06.db05-1022
-
Chu K., Lau T., and Carlsson P. Angiotensin II type 1 receptor blockade improves beta-cell function and glucose tolerance in a mouse model of type 2 diabetes Diabetes 55 2006 367 374 (Pubitemid 43343265)
-
(2006)
Diabetes
, vol.55
, Issue.2
, pp. 367-374
-
-
Kwan, Y.C.1
Lau, T.2
Carlsson, P.-O.3
Po, S.L.4
-
14
-
-
0035724736
-
Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats
-
Henriksen E., Jacob S., and Kinnick T. Selective angiotensin II receptor antagonism reduces insulin resistance in obese Zucker rats Hypertension 38 2001 884 890 (Pubitemid 34258687)
-
(2001)
Hypertension
, vol.38
, Issue.4
, pp. 884-890
-
-
Henriksen, E.J.1
Jacob, S.2
Kinnick, T.R.3
Teachey, M.K.4
Krekler, M.5
-
15
-
-
34548826277
-
Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis
-
Chan Y., and Leung P. Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis J Pharmacol Exp Ther 323 2007 10 18
-
(2007)
J Pharmacol Exp Ther
, vol.323
, pp. 10-18
-
-
Chan, Y.1
Leung, P.2
-
16
-
-
70449521071
-
Telmisartan attenuates fatty-acid-induced oxidative stress and NAD(P)H oxidase activity in pancreatic beta-cells
-
Saitoh Y., Wang H.W., and Ueno H. Telmisartan attenuates fatty-acid-induced oxidative stress and NAD(P)H oxidase activity in pancreatic beta-cells Diabetes Metab 35 2009 392 397
-
(2009)
Diabetes Metab
, vol.35
, pp. 392-397
-
-
Saitoh, Y.1
Wang, H.W.2
Ueno, H.3
-
17
-
-
0347990354
-
Direct and indirect mechanisms regulating secretion of glucagon-like peptide-1 and glucagon-like peptide-2
-
DOI 10.1139/y03-107
-
Brubaker P., and Anini Y. Direct and indirect mechanisms regulating secretion of glucagon-like peptide-1 and glucagon-like peptide-2 Can J Physiol Pharmacol 81 2003 1005 1012 (Pubitemid 38045829)
-
(2003)
Canadian Journal of Physiology and Pharmacology
, vol.81
, Issue.11
, pp. 1005-1012
-
-
Brubaker, P.L.1
Anini, Y.2
-
18
-
-
0036178672
-
Gut adaptation and the glucagon-like peptides
-
DOI 10.1136/gut.50.3.428
-
Drucker D. Gut adaptation and the glucagon-like peptides Gut 50 2002 428 435 (Pubitemid 34161064)
-
(2002)
Gut
, vol.50
, Issue.3
, pp. 428-435
-
-
Drucker, D.J.1
-
19
-
-
0026775150
-
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1
-
Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1 Proc Natl Acad Sci U S A 89 1992 8641 8645
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8641-8645
-
-
Thorens, B.1
-
20
-
-
0027425034
-
Cloning and functional expression of the human islet GLP-1 receptor: Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor
-
Thorens B., Porret A., and Bühler L. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor Diabetes 42 1993 1678 1682 (Pubitemid 23318127)
-
(1993)
Diabetes
, vol.42
, Issue.11
, pp. 1678-1682
-
-
Thorens, B.1
Porret, A.2
Buhler, L.3
Deng, S.-P.4
Morel, P.5
Widmann, C.6
-
21
-
-
0032143876
-
Glucagon-like peptide-1 (GLP-1): A gut hormone of potential interest in the treatment of diabetes
-
DOI 10.1002/(SICI)1521-1878(199808)20:8<642::AID-BIES7>3.0.CO;2-K
-
Ahrén B. Glucagon-like peptide-1 (GLP-1): a gut hormone of potential interest in the treatment of diabetes Bioessays 20 1998 642 651 (Pubitemid 28422224)
-
(1998)
BioEssays
, vol.20
, Issue.8
, pp. 642-651
-
-
Ahren, B.1
-
22
-
-
2942568445
-
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity
-
DOI 10.1007/s00125-004-1379-6
-
Buteau J., El-Assaad W., and Rhodes C. Glucagon-like peptide-1 prevents beta cell glucolipotoxicity Diabetologia 47 2004 806 815 (Pubitemid 38756992)
-
(2004)
Diabetologia
, vol.47
, Issue.5
, pp. 806-815
-
-
Buteau, J.1
El-Assaad, W.2
Rhodes, C.J.3
Mosenberg, L.4
Joly, E.5
Prentki, M.6
-
23
-
-
0038339191
-
CAMP promotes pancreatic β-cell survival via CREB-mediated induction of IRS2
-
DOI 10.1101/gad.1097103
-
Jhala U.S., Canettieri G., and Screaton R.A. cAMP promotes pancreatic beta-cell survival vial CREB-mediated induction of IRS2 Genes Dev 17 2003 1575 1580 (Pubitemid 36828785)
-
(2003)
Genes and Development
, vol.17
, Issue.13
, pp. 1575-1580
-
-
Jhala, U.S.1
Canettieri, G.2
Screaton, R.A.3
Kulkarni, R.N.4
Krajewski, S.5
Reed, J.6
Walker, J.7
Lin, X.8
White, M.9
Montminy, M.10
-
24
-
-
0032567937
-
Disruption of IRS-2 causes type 2 diabetes in mice
-
DOI 10.1038/36116
-
Withers D.J., Gutierrez J.S., and Towery H. Disruption of IRS-2 causes type 2 diabetes in mice Nature 391 1998 900 904 (Pubitemid 28157668)
-
(1998)
Nature
, vol.391
, Issue.6670
, pp. 900-904
-
-
Withers, D.J.1
Gutierrez, J.S.2
Towery, H.3
Burks, D.J.4
Ren, J.-M.5
Previs, S.6
Zhang, Y.7
Bernal, D.8
Pons, S.9
Shulman, G.I.10
Bonner-Weir, S.11
White, M.F.12
-
25
-
-
0345618266
-
Upregulation of insulin receptor substrate-2 in pancreatic β cells prevents diabetes
-
DOI 10.1172/JCI200318581
-
Hennige A.M., Burks D.J., and Ozcan U. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes J Clin Invest 112 2003 1521 1532 (Pubitemid 38056278)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.10
, pp. 1521-1532
-
-
Hennige, A.M.1
Burks, D.J.2
Ozcan, U.3
Kulkarni, R.N.4
Ye, J.5
Park, S.6
Schubert, M.7
Fisher, T.L.8
Dow, M.A.9
Leshan, R.10
Zakaria, M.11
Mossa-Basha, M.12
White, M.F.13
-
26
-
-
0036381989
-
Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice
-
Wang Q., and Brubaker P. Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice Diabetologia 2002 1263 1273
-
(2002)
Diabetologia
, pp. 1263-1273
-
-
Wang, Q.1
Brubaker, P.2
-
27
-
-
1842855402
-
Glucagon-like peptitle-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells
-
DOI 10.1007/s00125-004-1327-5
-
Wang Q., Li L., and Xu E. Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells Diabetologia 47 2004 478 487 (Pubitemid 38491244)
-
(2004)
Diabetologia
, vol.47
, Issue.3
, pp. 478-487
-
-
Wang, Q.1
Li, L.2
Xu, E.3
Wong, V.4
Rhodes, C.5
Brubaker, P.L.6
-
28
-
-
0034505107
-
Integrative mitogenic role of protein kinase B/Akt in β-cells
-
Trümper K., Trümper A., and Trusheim H. Integrative mitogenic role of protein kinase B/Akt in beta-cells Ann N Y Acad Sci 921 2000 242 250 (Pubitemid 32094549)
-
(2000)
Annals of the New York Academy of Sciences
, vol.921
, pp. 242-250
-
-
Trumper, K.1
Trumper, A.2
Trusheim, H.3
Arnold, R.4
Goke, B.5
Horsch, D.6
-
29
-
-
0030907987
-
PI3K: Downstream AKTion blocks apoptosis
-
DOI 10.1016/S0092-8674(00)81883-8
-
Franke T., Kaplan D., and Cantley L. PI3K: downstream AKTion blocks apoptosis Cell 88 1997 435 437 (Pubitemid 27154408)
-
(1997)
Cell
, vol.88
, Issue.4
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
30
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
-
Brunet A., Bonni A., and Zigmond M. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor Cell 96 1999 857 868 (Pubitemid 29165088)
-
(1999)
Cell
, vol.96
, Issue.6
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
31
-
-
3242656480
-
Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: A role for protein kinase B in the Akt?
-
Dickson L., and Rhodes C. Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am J Physiol Endocrinol Metab 287 2004 E192 E198
-
(2004)
Am J Physiol Endocrinol Metab
, vol.287
-
-
Dickson, L.1
Rhodes, C.2
-
32
-
-
1842863901
-
Aktion in the Nucleus
-
DOI 10.1161/01.RES.0000126699.49835.5D
-
Webster K. Aktion in the nucleus Circ Res 94 2004 856 859 (Pubitemid 38490060)
-
(2004)
Circulation Research
, vol.94
, Issue.7
, pp. 856-859
-
-
Webster, K.A.1
-
33
-
-
33745315716
-
Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic β-cell mass
-
DOI 10.2337/db05-0825
-
Buteau J., Spatz M., and Accili D. Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass Diabetes 55 2006 1190 1196 (Pubitemid 44195354)
-
(2006)
Diabetes
, vol.55
, Issue.5
, pp. 1190-1196
-
-
Buteau, J.1
Spatz, M.L.2
Accili, D.3
-
34
-
-
45449118936
-
Pioglitazone attenuates fatty acid-induced oxidative stress and apoptosis in pancreatic β-cells
-
DOI 10.1111/j.1463-1326.2007.00749.x
-
Saitoh Y., Chu C.P., and Noma K. Pioglitazone attenuates fatty acid-induced oxidative stress and apoptosis in pancreatic beta-cells Diabetes Obes Metab 10 2008 564 573 (Pubitemid 351850900)
-
(2008)
Diabetes, Obesity and Metabolism
, vol.10
, Issue.7
, pp. 564-573
-
-
Saitoh, Y.1
Chun-ping, C.2
Noma, K.3
Ueno, H.4
Mizuta, M.5
Nakazato, M.6
-
35
-
-
33644865024
-
The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation
-
Kawamori D., Kaneto H., and Nakatani Y. The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation J Biol Chem 281 2006 1091 1098
-
(2006)
J Biol Chem
, vol.281
, pp. 1091-1098
-
-
Kawamori, D.1
Kaneto, H.2
Nakatani, Y.3
-
36
-
-
73249116246
-
Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB
-
Cunha D.A., Ladrière L., and Ortis F. Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB Diabetes 58 2009 2851 2862
-
(2009)
Diabetes
, vol.58
, pp. 2851-2862
-
-
Cunha, D.A.1
Ladrière, L.2
Ortis, F.3
-
37
-
-
0037414781
-
Glucagon-like peptide-1 receptor signaling modulates β cell apoptosis
-
DOI 10.1074/jbc.M209423200
-
Li Y., Hansotia T., and Yusta B. Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis J Biol Chem 278 2003 471 478 (Pubitemid 36043598)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.1
, pp. 471-478
-
-
Li, Y.1
Hansotia, T.2
Yusta, B.3
Ris, F.4
Halban, P.A.5
Drueker, D.J.6
-
38
-
-
23944479411
-
Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: Role of protein kinase B
-
DOI 10.1007/s00125-005-1787-2
-
Li L., El-Kholy W., and Rhodes C. Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B Diabetologia 48 2005 1339 1349 (Pubitemid 41186100)
-
(2005)
Diabetologia
, vol.48
, Issue.7
, pp. 1339-1349
-
-
Li, L.1
El-Kholy, W.2
Rhodes, C.J.3
Brubaker, P.L.4
-
39
-
-
33644850386
-
Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function
-
Park S., Dong X., and Fisher T. Exendin-4 uses Irs2 signaling to mediate pancreatic beta cell growth and function J Biol Chem 281 2006 1159 1168
-
(2006)
J Biol Chem
, vol.281
, pp. 1159-1168
-
-
Park, S.1
Dong, X.2
Fisher, T.3
-
40
-
-
33745845825
-
Physiology of local renin-angiotensin systems
-
DOI 10.1152/physrev.00036.2005
-
Paul M., Poyan-Mehr A., and Kreutz R. Physiology of local renin-angiotensin systems Physiol Rev 86 2006 747 803 (Pubitemid 44033382)
-
(2006)
Physiological Reviews
, vol.86
, Issue.3
, pp. 747-803
-
-
Paul, M.1
Mehr, A.P.2
Kreutz, R.3
-
41
-
-
0034991799
-
Tissue renin-angiotensin system: Its expression, localization, regulation and potential role in the pancreas
-
DOI 10.1677/jme.0.0260155
-
Leung P., and Carlsson P. Tissue renin-angiotensin system: its expression, localization, regulation and potential role in the pancreas J Mol Endocrinol 26 2001 155 164 (Pubitemid 32514606)
-
(2001)
Journal of Molecular Endocrinology
, vol.26
, Issue.3
, pp. 155-164
-
-
Leung, P.S.1
Carlsson, P.O.2
-
42
-
-
33947526470
-
The physiology of a local renin-angiotensin system in the pancreas
-
DOI 10.1113/jphysiol.2006.126193
-
Leung P. The physiology of a local renin-angiotensin system in the pancreas J Physiol 580 2007 31 37 (Pubitemid 46470642)
-
(2007)
Journal of Physiology
, vol.580
, Issue.1
, pp. 31-37
-
-
Leung, P.S.1
-
43
-
-
45749135926
-
Effects of hyperglycemia on the angiotensin II receptor type 1 expression and insulin secretion in an INS-1E pancreatic beta-cell line
-
Leung K., and Leung P. Effects of hyperglycemia on angiotensin II receptor type 1 expression and insulin secretion in an INS-1E pancreatic beta-cell line JOP 9 2008 290 299 (Pubitemid 351864889)
-
(2008)
Journal of the Pancreas
, vol.9
, Issue.3
, pp. 290-299
-
-
Leung, K.K.1
Leung, P.S.2
-
44
-
-
1842475446
-
Improved Islet Morphology after Blockade of the Renin-Angiotensin System in the ZDF Rat
-
DOI 10.2337/diabetes.53.4.989
-
Tikellis C., Wookey P., and Candido R. Improved islet morphology after blockade of the renin-angiotensin system in the ZDF rat Diabetes 53 2004 989 997 (Pubitemid 38436611)
-
(2004)
Diabetes
, vol.53
, Issue.4
, pp. 989-997
-
-
Tikellis, C.1
Wookey, P.J.2
Candido, R.3
Andrikopoulos, S.4
Thomas, M.C.5
Cooper, M.E.6
-
45
-
-
0030023581
-
Pressor doses of angiotensin II increase hepatic glucose output and decrease insulin sensitivity in rats
-
Rao R. Pressor doses of angiotensin II increase hepatic glucose output and decrease insulin sensitivity in rats J Endocrinol 148 1996 311 318 (Pubitemid 26046925)
-
(1996)
Journal of Endocrinology
, vol.148
, Issue.2
, pp. 311-318
-
-
Rao, R.H.1
-
46
-
-
0036899150
-
Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling
-
DOI 10.1161/01.HYP.0000040262.48405.A8
-
Ogihara T., Asano T., and Ando K. Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling Hypertension 40 2002 872 879 (Pubitemid 35434909)
-
(2002)
Hypertension
, vol.40
, Issue.6
, pp. 872-879
-
-
Ogihara, T.1
Asano, T.2
Ando, K.3
Chiba, Y.4
Sakoda, H.5
Anai, M.6
Shojima, N.7
Ono, H.8
Onishi, Y.9
Fujishiro, M.10
Katagiri, H.11
Fukushima, Y.12
Kikuchi, M.13
Noguchi, N.14
Aburatani, H.15
Komuro, I.16
Fujita, T.17
-
47
-
-
21744452983
-
PPARγ-activating angiotensin type-1 receptor blockers induce adiponectin
-
DOI 10.1161/01.HYP.0000168046.19884.6a
-
Clasen R., Schupp M., and Foryst-Ludwig A. PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin Hypertension 46 2005 137 143 (Pubitemid 40946504)
-
(2005)
Hypertension
, vol.46
, Issue.1
, pp. 137-143
-
-
Clasen, R.1
Schupp, M.2
Foryst-Ludwig, A.3
Sprang, C.4
Clemenz, M.5
Krikov, M.6
Thone-Reineke, C.7
Unger, T.8
Kintscher, U.9
-
48
-
-
34250333856
-
Angiotensin II type 1 receptor antagonism mediates uncoupling protein 2-driven oxidative stress and ameliorates pancreatic islet β-cell function in young type 2 diabetic mice
-
DOI 10.1089/ars.2007.1590
-
Chu K., and Leung P. Angiotensin II type 1 receptor antagonism mediates uncoupling protein 2-driven oxidative stress and ameliorates pancreatic islet beta-cell function in young type 2 diabetic mice Antioxid Redox Signal 9 2007 869 878 (Pubitemid 46919590)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.7
, pp. 869-878
-
-
Kwan, Y.C.1
Leung, P.S.2
-
49
-
-
0344517365
-
Insulin receptor-related receptor is expressed in pancreatic β-cells and stimulates tyrosine phosphorylation of insulin receptor substrate-1 and- 2
-
DOI 10.2337/diabetes.48.6.1237
-
Hirayama I., Tamemoto H., and Yokota H. Insulin receptor-related receptor is expressed in pancreatic beta-cells and stimulates tyrosine phosphorylation of insulin receptor substrate-1 and -2 Diabetes 28 1999 1237 1244 (Pubitemid 29241020)
-
(1999)
Diabetes
, vol.48
, Issue.6
, pp. 1237-1244
-
-
Hirayama, I.1
Tamemoto, H.2
Yokota, H.3
Kubo, S.-K.4
Wang, J.5
Kuwano, H.6
Nagamachi, Y.7
Takeuchi, T.8
Izumi, T.9
-
50
-
-
33646200241
-
Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice
-
Shao J., Iwashita N., and Ikeda F. Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice Biochem Biophys Res Commun 344 2006 1224 1233
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 1224-1233
-
-
Shao, J.1
Iwashita, N.2
Ikeda, F.3
-
51
-
-
77449139439
-
Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction
-
Hennige A.M., Ranta F., and Heinzelmann I. Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction Diabetes 59 2010 119 127
-
(2010)
Diabetes
, vol.59
, pp. 119-127
-
-
Hennige, A.M.1
Ranta, F.2
Heinzelmann, I.3
-
52
-
-
0037147215
-
Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic β-cells (INS-1)
-
DOI 10.1074/jbc.M208756200
-
Wrede C., Dickson L., and Lingohr M. Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1) J Biol Chem 277 2002 49676 49684 (Pubitemid 36014411)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.51
, pp. 49676-49684
-
-
Wrede, C.E.1
Dickson, L.M.2
Lingohr, M.K.3
Briaud, I.4
Rhodes, C.J.5
-
53
-
-
69249139619
-
Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction
-
Zhang X., Yong W., and Lv J. Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction Endocrinology 150 2009 4065 4073
-
(2009)
Endocrinology
, vol.150
, pp. 4065-4073
-
-
Zhang, X.1
Yong, W.2
Lv, J.3
-
54
-
-
0035797921
-
Insulin regulation of gene expression through the forkhead transcription factor foxol (Fkhr) requires kinases distinct from Akt
-
DOI 10.1021/bi015532m
-
Nakae J., Kitamura T., and Ogawa W. Insulin regulation of gene expression through the forkhead transcription factor Foxo1 (Fkhr) requires kinases distinct from Akt Biochemistry 40 2001 11768 11776 (Pubitemid 32906038)
-
(2001)
Biochemistry
, vol.40
, Issue.39
, pp. 11768-11776
-
-
Nakae, J.1
Kitamura, T.2
Ogawa, W.3
Kasuga, M.4
Accili, D.5
|