Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-α or EGF, augments pancreatic β-cell proliferation

Diabetes

Volumn 51, Issue 4, 2002, Pages 966-976

  Lingohr, Melissa K ^a,b   Dickson, Lorna M ^a,b   McCuaig, Jill F ^a,b   Hugl, Sigrun R ^a,b   Twardzik, Daniel R ^c   Rhodes, Christopher J ^a,b  

^a PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Stem Cell Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; S6 KINASE; SERINE; SOMATOMEDIN C; THREONINE; TRANSFORMING GROWTH FACTOR ALPHA; TRITIUM;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MITOGENESIS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

EID: 0036224165     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.51.4.966     Document Type: Article

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