-
1
-
-
68549111147
-
The (Pro)renin receptor: Site-specific and functional linkage to the vacuolar H + -ATPase in the kidney
-
19546380 1:CAS:528:DC%2BD1MXosFWiurs%3D 10.1161/HYPERTENSIONAHA.109. 128645
-
+ -ATPase in the kidney. Hypertension 54:261-269
-
(2009)
Hypertension
, vol.54
, pp. 261-269
-
-
Advani, A.1
Kelly, D.J.2
Cox, A.J.3
White, K.E.4
Advani, S.L.5
Thai, K.6
Connelly, K.A.7
Yuen, D.8
Trogadis, J.9
Herzenberg, A.M.10
Kuliszewski, M.A.11
Leong-Poi, H.12
Gilbert, R.E.13
-
2
-
-
4444220604
-
Identification of 315 genes essential for early zebrafish development
-
15256591 1:CAS:528:DC%2BD2cXnslCltLY%3D 10.1073/pnas.0403929101
-
Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N (2004) Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci U S A 101:12792-12797
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12792-12797
-
-
Amsterdam, A.1
Nissen, R.M.2
Sun, Z.3
Swindell, E.C.4
Farrington, S.5
Hopkins, N.6
-
3
-
-
38649119156
-
The second life of the (pro)renin receptor
-
18205100 1:CAS:528:DC%2BD1cXhs1yqsbo%3D 10.3317/jraas.2007.031
-
Bader M (2007) The second life of the (pro)renin receptor. J Renin Angiotensin Aldosterone Syst 8:205-208
-
(2007)
J Renin Angiotensin Aldosterone Syst
, vol.8
, pp. 205-208
-
-
Bader, M.1
-
4
-
-
35848948398
-
Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
-
17984666 1:CAS:528:DC%2BD2sXht1Kjsr7P 10.1097/HJH.0b013e3282f05bae
-
Batenburg WW, Krop M, Garrelds IM, de Vries R, de Bruin RJA, Burcklé CA, Müller DN, Bader M, Nguyen G, Danser AHJ (2007) Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens 25:2441-2453
-
(2007)
J Hypertens
, vol.25
, pp. 2441-2453
-
-
Batenburg, W.W.1
Krop, M.2
Garrelds, I.M.3
De Vries, R.4
De Bruin, R.J.A.5
Burcklé, C.A.6
Müller, D.N.7
Bader, M.8
Nguyen, G.9
Danser, A.H.J.10
-
5
-
-
44849107992
-
Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells
-
18388329 1:CAS:528:DC%2BD1cXlsFOju7w%3D 10.1161/ATVBAHA.108.164210
-
Batenburg WW, de Bruin RJA, van Gool JMG, Müller DN, Bader M, Nguyen G, Danser AHJ (2008) Aliskiren-binding increases the half life of renin and prorenin in rat aortic vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 28:1151-1157
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1151-1157
-
-
Batenburg, W.W.1
De Bruin, R.J.A.2
Van Gool, J.M.G.3
Müller, D.N.4
Bader, M.5
Nguyen, G.6
Danser, A.H.J.7
-
6
-
-
83155180323
-
Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: Does (pro)renin-(pro)renin receptor interaction actually occur?
-
22025376 1:CAS:528:DC%2BC3MXhsVOju7fM 10.1161/HYPERTENSIONAHA.111.180737
-
Batenburg WW, Lu X, Leijten F, Maschke U, Müller DN, Danser AHJ (2011) Renin- and prorenin-induced effects in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor: does (pro)renin-(pro)renin receptor interaction actually occur? Hypertension 58:1111-1119
-
(2011)
Hypertension
, vol.58
, pp. 1111-1119
-
-
Batenburg, W.W.1
Lu, X.2
Leijten, F.3
Maschke, U.4
Müller, D.N.5
Danser, A.H.J.6
-
7
-
-
79958089973
-
Qualitative and quantitative analyses of (pro)renin receptor in the medium of cultured human umbilical vein endothelial cells
-
21412241 1:CAS:528:DC%2BC3MXntVyjtrk%3D 10.1038/hr.2011.26
-
Biswas KB, Nabi AN, Arai Y, Nakagawa T, Ebihara A, Ichihara A, Inagami T, Suzuki F (2011) Qualitative and quantitative analyses of (pro)renin receptor in the medium of cultured human umbilical vein endothelial cells. Hypertens Res 34:735-739
-
(2011)
Hypertens Res
, vol.34
, pp. 735-739
-
-
Biswas, K.B.1
Nabi, A.N.2
Arai, Y.3
Nakagawa, T.4
Ebihara, A.5
Ichihara, A.6
Inagami, T.7
Suzuki, F.8
-
8
-
-
79951673075
-
A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals
-
21157371 1:CAS:528:DC%2BC3MXhvVyktb0%3D 10.1097/HJH.0b013e328341d117
-
Brugts JJ, Isaacs A, de Maat MP, Boersma E, van Duijn CM, Akkerhuis KM, Uitterlinden AG, Witteman JC, Cambien F, Ceconi C, Remme W, Bertrand M, Ninomiya T, Harrap S, Chalmers J, Macmahon S, Fox K, Ferrari R, Simoons ML, Danser AHJ (2011) A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals. J Hypertens 29:509-519
-
(2011)
J Hypertens
, vol.29
, pp. 509-519
-
-
Brugts, J.J.1
Isaacs, A.2
De Maat, M.P.3
Boersma, E.4
Van Duijn, C.M.5
Akkerhuis, K.M.6
Uitterlinden, A.G.7
Witteman, J.C.8
Cambien, F.9
Ceconi, C.10
Remme, W.11
Bertrand, M.12
Ninomiya, T.13
Harrap, S.14
Chalmers, J.15
MacMahon, S.16
Fox, K.17
Ferrari, R.18
Simoons, M.L.19
Danser, A.H.J.20
more..
-
9
-
-
77956635784
-
Wnt/frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor
-
20579883 1:CAS:528:DC%2BC3cXptlCmurw%3D 10.1016/j.cub.2010.05.028
-
Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M (2010) Wnt/frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol 20:1263-1268
-
(2010)
Curr Biol
, vol.20
, pp. 1263-1268
-
-
Buechling, T.1
Bartscherer, K.2
Ohkawara, B.3
Chaudhary, V.4
Spirohn, K.5
Niehrs, C.6
Boutros, M.7
-
10
-
-
33644983896
-
Elevated blood pressure and heart rate in human renin receptor transgenic rats
-
16401765 10.1161/01.HYP.0000199912.47657.04 1:CAS:528: DC%2BD28XhsFKlu7s%3D
-
Burcklé CA, Danser AHJ, Müller DN, Garrelds IM, Gasc JM, Popova E, Plehm R, Peters J, Bader M, Nguyen G (2006) Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 47:552-556
-
(2006)
Hypertension
, vol.47
, pp. 552-556
-
-
Burcklé, C.A.1
Danser, A.H.J.2
Müller, D.N.3
Garrelds, I.M.4
Gasc, J.M.5
Popova, E.6
Plehm, R.7
Peters, J.8
Bader, M.9
Nguyen, G.10
-
11
-
-
73349109829
-
Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver
-
19841286 1:CAS:528:DC%2BD1MXhtl2qurvL 10.1161/HYPERTENSIONAHA.109.138495
-
Campbell DJ, Karam H, Ménard J, Bruneval P, Mullins JJ (2009) Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver. Hypertension 54:1248-1253
-
(2009)
Hypertension
, vol.54
, pp. 1248-1253
-
-
Campbell, D.J.1
Karam, H.2
Ménard, J.3
Bruneval, P.4
Mullins, J.J.5
-
12
-
-
80054761708
-
Combined angiotensin-converting enzyme inhibition and receptor blockade associate with increased risk of cardiovascular death in hemodialysis patients
-
21775975 1:CAS:528:DC%2BC3MXhtlaiur3M 10.1038/ki.2011.228
-
Chan KE, Ikizler TA, Gamboa JL, Yu C, Hakim RM, Brown NJ (2011) Combined angiotensin-converting enzyme inhibition and receptor blockade associate with increased risk of cardiovascular death in hemodialysis patients. Kidney Int 80:978-985
-
(2011)
Kidney Int
, vol.80
, pp. 978-985
-
-
Chan, K.E.1
Ikizler, T.A.2
Gamboa, J.L.3
Yu, C.4
Hakim, R.M.5
Brown, N.J.6
-
13
-
-
79960134417
-
Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression
-
21737546 1:CAS:528:DC%2BC3MXhtVSnsL%2FL 10.1681/ASN.2010111149
-
Cheng H, Fan X, Moeckel GW, Harris RC (2011) Podocyte COX-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression. J Am Soc Nephrol 22:1240-1251
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 1240-1251
-
-
Cheng, H.1
Fan, X.2
Moeckel, G.W.3
Harris, R.C.4
-
14
-
-
79958135759
-
(Pro)renin promotes fibrosis gene expression in HEK cells through a Nox4-dependent mechanism
-
21411480 1:CAS:528:DC%2BC3MXot1Grt7c%3D 10.1152/ajprenal.00119.2010
-
Clavreul N, Sansilvestri-Morel P, Magard D, Verbeuren TJ, Rupin A (2011) (Pro)renin promotes fibrosis gene expression in HEK cells through a Nox4-dependent mechanism. Am J Physiol Renal Physiol 300:F1310-1318
-
(2011)
Am J Physiol Renal Physiol
, vol.300
, pp. 1310-1318
-
-
Clavreul, N.1
Sansilvestri-Morel, P.2
Magard, D.3
Verbeuren, T.J.4
Rupin, A.5
-
15
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
17081971 1:CAS:528:DC%2BD28Xht1WhtbbN 10.1016/j.cell.2006.10.018
-
Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127:469-480
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
16
-
-
79955604483
-
The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy
-
21505358 1:CAS:528:DC%2BC3MXlsFKju7o%3D 10.1097/HJH.0b013e3283462674
-
Connelly KA, Advani A, Kim S, Advani SL, Zhang M, White KE, Kim YM, Parker C, Thai K, Krum H, Kelly DJ, Gilbert RE (2011) The cardiac (pro)renin receptor is primarily expressed in myocyte transverse tubules and is increased in experimental diabetic cardiomyopathy. J Hypertens 29:1175-1184
-
(2011)
J Hypertens
, vol.29
, pp. 1175-1184
-
-
Connelly, K.A.1
Advani, A.2
Kim, S.3
Advani, S.L.4
Zhang, M.5
White, K.E.6
Kim, Y.M.7
Parker, C.8
Thai, K.9
Krum, H.10
Kelly, D.J.11
Gilbert, R.E.12
-
17
-
-
68049088904
-
A role of the (pro)renin receptor in neuronal cell differentiation
-
19474391 1:CAS:528:DC%2BD1MXhtVahtrfL 10.1152/ajpregu.90832.2008
-
Contrepas A, Walker J, Koulakoff A, Franek KJ, Qadri F, Giaume C, Corvol P, Schwartz CE, Nguyen G (2009) A role of the (pro)renin receptor in neuronal cell differentiation. Am J Physiol Regul Integr Comp Physiol 297:R250-257
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.297
, pp. 250-257
-
-
Contrepas, A.1
Walker, J.2
Koulakoff, A.3
Franek, K.J.4
Qadri, F.5
Giaume, C.6
Corvol, P.7
Schwartz, C.E.8
Nguyen, G.9
-
18
-
-
67049144916
-
Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma
-
19380613 1:CAS:528:DC%2BD1MXlslCitbs%3D 10.1161/HYPERTENSIONAHA.108. 127258
-
Cousin C, Bracquart D, Contrepas A, Corvol P, Muller L, Nguyen G (2009) Soluble form of the (pro)renin receptor generated by intracellular cleavage by furin is secreted in plasma. Hypertension 53:1077-1082
-
(2009)
Hypertension
, vol.53
, pp. 1077-1082
-
-
Cousin, C.1
Bracquart, D.2
Contrepas, A.3
Corvol, P.4
Muller, L.5
Nguyen, G.6
-
19
-
-
75649120756
-
Requirement of prorenin receptor and vacuolar H + -ATPase-mediated acidification for Wnt signaling
-
20093472 1:CAS:528:DC%2BC3cXnt1ahsQ%3D%3D 10.1126/science.1179802
-
+ -ATPase-mediated acidification for Wnt signaling. Science 327:459-463
-
(2010)
Science
, vol.327
, pp. 459-463
-
-
Cruciat, C.M.1
Ohkawara, B.2
Acebron, S.P.3
Karaulanov, E.4
Reinhard, C.5
Ingelfinger, D.6
Boutros, M.7
Niehrs, C.8
-
20
-
-
68549136748
-
+-ATPase
-
19546373 1:CAS:528:DC%2BD1MXpslyhu7k%3D 10.1161/HYPERTENSIONAHA.109. 135236
-
+-ATPase. Hypertension 54:219-221
-
(2009)
Hypertension
, vol.54
, pp. 219-221
-
-
Danser, A.H.J.1
-
21
-
-
74349117848
-
The increase in renin during renin inhibition: Does it result in harmful effects by the (pro)renin receptor?
-
19893565 1:CAS:528:DC%2BC3cXpt1Oq 10.1038/hr.2009.186
-
Danser AHJ (2010) The increase in renin during renin inhibition: does it result in harmful effects by the (pro)renin receptor? Hypertens Res 33:4-10
-
(2010)
Hypertens Res
, vol.33
, pp. 4-10
-
-
Danser, A.H.J.1
-
22
-
-
0036852758
-
Prorenin uptake in the heart: A prerequisite for local angiotensin generation?
-
1:CAS:528:DC%2BD38XosVeku7w%3D 10.1006/jmcc.2002.2078
-
Danser AHJ, Saris JJ (2002) Prorenin uptake in the heart: a prerequisite for local angiotensin generation? J Mol Cell Cardiol 34:1463-1472
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 1463-1472
-
-
Danser, A.H.J.1
Saris, J.J.2
-
23
-
-
0028229413
-
Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis
-
8021006 1:CAS:528:DyaK2cXlt1Kjtrc%3D 10.1161/01.HYP.24.1.37
-
Danser AHJ, van Kats JP, Admiraal PJ, Derkx FHM, Lamers JM, Verdouw PD, Saxena PR, Schalekamp MADH (1994) Cardiac renin and angiotensins. Uptake from plasma versus in situ synthesis. Hypertension 24:37-48
-
(1994)
Hypertension
, vol.24
, pp. 37-48
-
-
Danser, A.H.J.1
Van Kats, J.P.2
Admiraal, P.J.3
Derkx, F.H.M.4
Lamers, J.M.5
Verdouw, P.D.6
Saxena, P.R.7
Schalekamp, M.8
-
24
-
-
15144347939
-
Determinants of interindividual variation of renin and prorenin concentrations: Evidence for a sexual dimorphism of (pro)renin levels in humans
-
9663926 1:CAS:528:DyaK1cXktFers7c%3D 10.1097/00004872-199816060-00017
-
Danser AHJ, Derkx FHM, Schalekamp MADH, Hense HW, Riegger GA, Schunkert H (1998) Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans. J Hypertens 16:853-862
-
(1998)
J Hypertens
, vol.16
, pp. 853-862
-
-
Danser, A.H.J.1
Derkx, F.H.M.2
Schalekamp, M.3
Hense, H.W.4
Riegger, G.A.5
Schunkert, H.6
-
25
-
-
0032787740
-
Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus
-
10491762 1:CAS:528:DyaK1MXkvF2ksbc%3D 10.1007/s001250051260
-
Deinum J, Ronn B, Mathiesen E, Derkx FHM, Hop WC, Schalekamp MADH (1999) Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus. Diabetologia 42:1006-1010
-
(1999)
Diabetologia
, vol.42
, pp. 1006-1010
-
-
Deinum, J.1
Ronn, B.2
Mathiesen, E.3
Derkx, F.H.M.4
Hop, W.C.5
Schalekamp, M.6
-
26
-
-
0026482523
-
Nonproteolytic «activation» of prorenin by active site-directed renin inhibitors as demonstrated by renin-specific monoclonal antibody
-
1429632 1:CAS:528:DyaK38XlvVOitrY%3D
-
Derkx FHM, Deinum J, Lipovski M, Verhaar M, Fischli W, Schalekamp MADH (1992) Nonproteolytic «activation» of prorenin by active site-directed renin inhibitors as demonstrated by renin-specific monoclonal antibody. J Biol Chem 267:22837-22842
-
(1992)
J Biol Chem
, vol.267
, pp. 22837-22842
-
-
Derkx, F.H.M.1
Deinum, J.2
Lipovski, M.3
Verhaar, M.4
Fischli, W.5
Schalekamp, M.6
-
27
-
-
0032502765
-
Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
-
9535870 1:CAS:528:DyaK1cXis1eltb4%3D 10.1074/jbc.273.15.8890
-
Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, Marumo F, Inagami T (1998) Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. J Biol Chem 273:8890-8896
-
(1998)
J Biol Chem
, vol.273
, pp. 8890-8896
-
-
Eguchi, S.1
Numaguchi, K.2
Iwasaki, H.3
Matsumoto, T.4
Yamakawa, T.5
Utsunomiya, H.6
Motley, E.D.7
Kawakatsu, H.8
Owada, K.M.9
Hirata, Y.10
Marumo, F.11
Inagami, T.12
-
28
-
-
80054769791
-
Detrimental effects of dual ACEI-ARB therapy: Is the (pro)renin receptor the culprit?
-
21997507 1:CAS:528:DC%2BC3MXhtlaiurzI 10.1038/ki.2011.264
-
Elijovich F, Laffer CL (2011) Detrimental effects of dual ACEI-ARB therapy: is the (pro)renin receptor the culprit? Kidney Int 80:911-914
-
(2011)
Kidney Int
, vol.80
, pp. 911-914
-
-
Elijovich, F.1
Laffer, C.L.2
-
29
-
-
46449118638
-
Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats
-
18490518 1:CAS:528:DC%2BD1cXntVaisL0%3D 10.1161/HYPERTENSIONAHA.107. 108845
-
Feldman DL, Jin L, Xuan H, Contrepas A, Zhou Y, Webb RL, Müller DN, Feldt S, Cumin F, Maniara W, Persohn E, Schuetz H, Danser AHJ, Nguyen G (2008) Effects of aliskiren on blood pressure, albuminuria, and (pro)renin receptor expression in diabetic TG(mRen-2)27 rats. Hypertension 52:130-136
-
(2008)
Hypertension
, vol.52
, pp. 130-136
-
-
Feldman, D.L.1
Jin, L.2
Xuan, H.3
Contrepas, A.4
Zhou, Y.5
Webb, R.L.6
Müller, D.N.7
Feldt, S.8
Cumin, F.9
Maniara, W.10
Persohn, E.11
Schuetz, H.12
Danser, A.H.J.13
Nguyen, G.14
-
30
-
-
39749098706
-
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide
-
18212269 1:CAS:528:DC%2BD1cXhvVemsr4%3D 10.1161/HYPERTENSIONAHA.107. 101444
-
Feldt S, Batenburg WW, Mazak I, Maschke U, Wellner M, Kvakan H, Dechend R, Fiebeler A, Burcklé CA, Contrepas A, Danser AHJ, Bader M, Nguyen G, Luft FC, Müller DN (2008) Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension 51:682-688
-
(2008)
Hypertension
, vol.51
, pp. 682-688
-
-
Feldt, S.1
Batenburg, W.W.2
Mazak, I.3
Maschke, U.4
Wellner, M.5
Kvakan, H.6
Dechend, R.7
Fiebeler, A.8
Burcklé, C.A.9
Contrepas, A.10
Danser, A.H.J.11
Bader, M.12
Nguyen, G.13
Luft, F.C.14
Müller, D.N.15
-
31
-
-
42249089770
-
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling
-
18235083 1:CAS:528:DC%2BD1cXkvFOhsbo%3D 10.1681/ASN.2007091030
-
Feldt S, Maschke U, Dechend R, Luft FC, Müller DN (2008) The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol 19:743-748
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 743-748
-
-
Feldt, S.1
Maschke, U.2
Dechend, R.3
Luft, F.C.4
Müller, D.N.5
-
32
-
-
79953227634
-
Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats
-
21321306 1:CAS:528:DC%2BC3MXjt1Gnsb8%3D 10.1161/HYPERTENSIONAHA.110. 167957
-
Gonzalez AA, Lara LS, Luffman C, Seth DM, Prieto MC (2011) Soluble form of the (pro)renin receptor is augmented in the collecting duct and urine of chronic angiotensin II-dependent hypertensive rats. Hypertension 57:859-864
-
(2011)
Hypertension
, vol.57
, pp. 859-864
-
-
Gonzalez, A.A.1
Lara, L.S.2
Luffman, C.3
Seth, D.M.4
Prieto, M.C.5
-
33
-
-
77955286565
-
Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling
-
20519507 1:CAS:528:DC%2BC3cXpsFemsbk%3D 10.1074/jbc.M109.091256
-
He W, Tan R, Dai C, Li Y, Wang D, Hao S, Kahn M, Liu Y (2010) Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling. J Biol Chem 285:24665-24675
-
(2010)
J Biol Chem
, vol.285
, pp. 24665-24675
-
-
He, W.1
Tan, R.2
Dai, C.3
Li, Y.4
Wang, D.5
Hao, S.6
Kahn, M.7
Liu, Y.8
-
34
-
-
77956635633
-
Regulation of frizzled-dependent planar polarity signaling by a V-ATPase subunit
-
20579879 1:CAS:528:DC%2BC3cXptlCmuro%3D 10.1016/j.cub.2010.05.057
-
Hermle T, Saltukoglu D, Grunewald J, Walz G, Simons M (2010) Regulation of frizzled-dependent planar polarity signaling by a V-ATPase subunit. Curr Biol 20:1269-1276
-
(2010)
Curr Biol
, vol.20
, pp. 1269-1276
-
-
Hermle, T.1
Saltukoglu, D.2
Grunewald, J.3
Walz, G.4
Simons, M.5
-
35
-
-
60649085140
-
Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: The Ohasama study
-
19131936 1:CAS:528:DC%2BD1MXit1Oktro%3D 10.1038/ajh.2008.357
-
Hirose T, Hashimoto M, Totsune K, Metoki H, Asayama K, Kikuya M, Sugimoto K, Katsuya T, Ohkubo T, Hashimoto J, Rakugi H, Takahashi K, Imai Y (2009) Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study. Am J Hypertens 22:294-299
-
(2009)
Am J Hypertens
, vol.22
, pp. 294-299
-
-
Hirose, T.1
Hashimoto, M.2
Totsune, K.3
Metoki, H.4
Asayama, K.5
Kikuya, M.6
Sugimoto, K.7
Katsuya, T.8
Ohkubo, T.9
Hashimoto, J.10
Rakugi, H.11
Takahashi, K.12
Imai, Y.13
-
36
-
-
79953704792
-
Association of (pro)renin receptor gene polymorphisms with lacunar infarction and left ventricular hypertrophy in Japanese women: The Ohasama study
-
21228785 1:CAS:528:DC%2BC3MXkt1eitbo%3D 10.1038/hr.2010.274
-
Hirose T, Hashimoto M, Totsune K, Metoki H, Hara A, Satoh M, Kikuya M, Ohkubo T, Asayama K, Kondo T, Kamide K, Katsuya T, Ogihara T, Izumi S, Rakugi H, Takahashi K, Imai Y (2011) Association of (pro)renin receptor gene polymorphisms with lacunar infarction and left ventricular hypertrophy in Japanese women: the Ohasama study. Hypertens Res 34:530-535
-
(2011)
Hypertens Res
, vol.34
, pp. 530-535
-
-
Hirose, T.1
Hashimoto, M.2
Totsune, K.3
Metoki, H.4
Hara, A.5
Satoh, M.6
Kikuya, M.7
Ohkubo, T.8
Asayama, K.9
Kondo, T.10
Kamide, K.11
Katsuya, T.12
Ogihara, T.13
Izumi, S.14
Rakugi, H.15
Takahashi, K.16
Imai, Y.17
-
37
-
-
71949102843
-
Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (pro)renin receptor expression
-
19861503 1:CAS:528:DC%2BD1MXhsFGqtbrK 10.1210/en.2009-0442
-
Huang J, Siragy HM (2009) Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (pro)renin receptor expression. Endocrinology 150:5557-5565
-
(2009)
Endocrinology
, vol.150
, pp. 5557-5565
-
-
Huang, J.1
Siragy, H.M.2
-
38
-
-
30944469631
-
Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
-
16374430 1:CAS:528:DC%2BD28Xpt1Wqtw%3D%3D 10.1038/sj.ki.5000011
-
Huang Y, Wongamorntham S, Kasting J, McQuillan D, Owens RT, Yu L, Noble NA, Border W (2006) Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 69:105-113
-
(2006)
Kidney Int
, vol.69
, pp. 105-113
-
-
Huang, Y.1
Wongamorntham, S.2
Kasting, J.3
McQuillan, D.4
Owens, R.T.5
Yu, L.6
Noble, N.A.7
Border, W.8
-
39
-
-
34347350179
-
Renin-stimulated TGF-beta1 expression is regulated by a mitogen-activated protein kinase in mesangial cells
-
17396111 1:CAS:528:DC%2BD2sXntVCjtL0%3D 10.1038/sj.ki.5002243
-
Huang Y, Noble NA, Zhang J, Xu C, Border WA (2007) Renin-stimulated TGF-beta1 expression is regulated by a mitogen-activated protein kinase in mesangial cells. Kidney Int 72:45-52
-
(2007)
Kidney Int
, vol.72
, pp. 45-52
-
-
Huang, Y.1
Noble, N.A.2
Zhang, J.3
Xu, C.4
Border, W.A.5
-
40
-
-
9644283069
-
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the «handle» region for nonproteolytic activation of prorenin
-
15489960 1:CAS:528:DC%2BD2cXovVens74%3D
-
Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, Koura Y, Nishiyama A, Okada H, Uddin MN, Nabi AH, Ishida Y, Inagami T, Saruta T (2004) Inhibition of diabetic nephropathy by a decoy peptide corresponding to the «handle» region for nonproteolytic activation of prorenin. J Clin Invest 114:1128-1135
-
(2004)
J Clin Invest
, vol.114
, pp. 1128-1135
-
-
Ichihara, A.1
Hayashi, M.2
Kaneshiro, Y.3
Suzuki, F.4
Nakagawa, T.5
Tada, Y.6
Koura, Y.7
Nishiyama, A.8
Okada, H.9
Uddin, M.N.10
Nabi, A.H.11
Ishida, Y.12
Inagami, T.13
Saruta, T.14
-
41
-
-
33646160993
-
Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
-
16585419 1:CAS:528:DC%2BD28XjsVeks78%3D 10.1161/01.HYP.0000215838.48170. 0b
-
Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, Nishiyama A, Inagami T, Hayashi M (2006) Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 47:894-900
-
(2006)
Hypertension
, vol.47
, pp. 894-900
-
-
Ichihara, A.1
Kaneshiro, Y.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
Nakagawa, T.6
Nishiyama, A.7
Inagami, T.8
Hayashi, M.9
-
42
-
-
33745824649
-
Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
-
16738017 1:CAS:528:DC%2BD28Xntlanurg%3D 10.1681/ASN.2006010029
-
Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, Nabi AH, Nishiyama A, Sugaya T, Hayashi M, Inagami T (2006) Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice. J Am Soc Nephrol 17:1950-1961
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1950-1961
-
-
Ichihara, A.1
Suzuki, F.2
Nakagawa, T.3
Kaneshiro, Y.4
Takemitsu, T.5
Sakoda, M.6
Nabi, A.H.7
Nishiyama, A.8
Sugaya, T.9
Hayashi, M.10
Inagami, T.11
-
43
-
-
77749239824
-
Possible roles of human (pro)renin receptor suggested by recent clinical and experimental findings
-
20019703 1:CAS:528:DC%2BC3cXislKhsb4%3D 10.1038/hr.2009.214
-
Ichihara A, Sakoda M, Kurauchi-Mito A, Narita T, Kinouchi K, Murohashi-Bokuda K, Itoh H (2010) Possible roles of human (pro)renin receptor suggested by recent clinical and experimental findings. Hypertens Res 33:177-180
-
(2010)
Hypertens Res
, vol.33
, pp. 177-180
-
-
Ichihara, A.1
Sakoda, M.2
Kurauchi-Mito, A.3
Narita, T.4
Kinouchi, K.5
Murohashi-Bokuda, K.6
Itoh, H.7
-
44
-
-
0026028187
-
Relationship of follicular fluid prorenin to oocyte maturation, steroid levels, and outcome of in vitro fertilization
-
1986016 1:STN:280:DyaK3M%2Fptlelug%3D%3D 10.1210/jcem-72-1-165
-
Itskovitz J, Rubattu S, Rosenwaks Z, Liu HC, Sealey JE (1991) Relationship of follicular fluid prorenin to oocyte maturation, steroid levels, and outcome of in vitro fertilization. J Clin Endocrinol Metab 72:165-171
-
(1991)
J Clin Endocrinol Metab
, vol.72
, pp. 165-171
-
-
Itskovitz, J.1
Rubattu, S.2
Rosenwaks, Z.3
Liu, H.C.4
Sealey, J.E.5
-
45
-
-
0026672853
-
Highest concentrations of prorenin and human chorionic gonadotropin in gestational sacs during early human pregnancy
-
1517384 1:CAS:528:DyaK38XmtVGrtrY%3D 10.1210/jc.75.3.906
-
Itskovitz J, Rubattu S, Levron J, Sealey JE (1992) Highest concentrations of prorenin and human chorionic gonadotropin in gestational sacs during early human pregnancy. J Clin Endocrinol Metab 75:906-910
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 906-910
-
-
Itskovitz, J.1
Rubattu, S.2
Levron, J.3
Sealey, J.E.4
-
47
-
-
33747060126
-
Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
-
16807542 1:CAS:528:DC%2BD28XnvVyltLo%3D 10.1038/sj.ki.5001627
-
Kaneshiro Y, Ichihara A, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, Hayashi M, Inagami T (2006) Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 70:641-646
-
(2006)
Kidney Int
, vol.70
, pp. 641-646
-
-
Kaneshiro, Y.1
Ichihara, A.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
Nakagawa, T.6
Hayashi, M.7
Inagami, T.8
-
48
-
-
34249881320
-
Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats
-
17494887 1:CAS:528:DC%2BD2sXnt1Wjsrw%3D 10.1681/ASN.2006091062
-
Kaneshiro Y, Ichihara A, Sakoda M, Takemitsu T, Nabi AH, Uddin MN, Nakagawa T, Nishiyama A, Suzuki F, Inagami T, Itoh H (2007) Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats. J Am Soc Nephrol 18:1789-1795
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1789-1795
-
-
Kaneshiro, Y.1
Ichihara, A.2
Sakoda, M.3
Takemitsu, T.4
Nabi, A.H.5
Uddin, M.N.6
Nakagawa, T.7
Nishiyama, A.8
Suzuki, F.9
Inagami, T.10
Itoh, H.11
-
49
-
-
45849143635
-
The collecting duct is the major source of prorenin in diabetes
-
18413493 1:CAS:528:DC%2BD1cXlvFait78%3D 10.1161/HYPERTENSIONAHA.107. 107268
-
Kang JJ, Toma I, Sipos A, Meer EJ, Vargas SL, Peti-Peterdi J (2008) The collecting duct is the major source of prorenin in diabetes. Hypertension 51:1597-1604
-
(2008)
Hypertension
, vol.51
, pp. 1597-1604
-
-
Kang, J.J.1
Toma, I.2
Sipos, A.3
Meer, E.J.4
Vargas, S.L.5
Peti-Peterdi, J.6
-
50
-
-
79960425136
-
Wnt/beta-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival
-
21613219 1:CAS:528:DC%2BC3MXovFCku70%3D 10.1074/jbc.M111.223164
-
Kato H, Gruenwald A, Suh JH, Miner JH, Barisoni-Thomas L, Taketo MM, Faul C, Millar SE, Holzman LB, Susztak K (2011) Wnt/beta-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. J Biol Chem 286:26003-26015
-
(2011)
J Biol Chem
, vol.286
, pp. 26003-26015
-
-
Kato, H.1
Gruenwald, A.2
Suh, J.H.3
Miner, J.H.4
Barisoni-Thomas, L.5
Taketo, M.M.6
Faul, C.7
Millar, S.E.8
Holzman, L.B.9
Susztak, K.10
-
51
-
-
0031956497
-
Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes
-
9568890 1:CAS:528:DyaK1cXisFSntbg%3D 10.1002/pro.5560070401
-
Khan AR, James MN (1998) Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes. Protein Sci 7:815-836
-
(1998)
Protein Sci
, vol.7
, pp. 815-836
-
-
Khan, A.R.1
James, M.N.2
-
52
-
-
77954762963
-
The (pro)renin receptor/ATP6AP2 is essential for vacuolar H + -ATPase assembly in murine cardiomyocytes
-
20570919 1:CAS:528:DC%2BC3cXosV2hs7Y%3D 10.1161/CIRCRESAHA.110.224667
-
+ -ATPase assembly in murine cardiomyocytes. Circ Res 107:30-34
-
(2010)
Circ Res
, vol.107
, pp. 30-34
-
-
Kinouchi, K.1
Ichihara, A.2
Sano, M.3
Sun-Wada, G.H.4
Wada, Y.5
Kurauchi-Mito, A.6
Bokuda, K.7
Narita, T.8
Oshima, Y.9
Sakoda, M.10
Tamai, Y.11
Sato, H.12
Fukuda, K.13
Itoh, H.14
-
53
-
-
0026637316
-
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors
-
1323236 1:CAS:528:DyaK38Xlt1Cmtb8%3D 10.1146/annurev.bi.61.070192.001515
-
Kornfeld S (1992) Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptors. Annu Rev Biochem 61:307-330
-
(1992)
Annu Rev Biochem
, vol.61
, pp. 307-330
-
-
Kornfeld, S.1
-
54
-
-
34548490929
-
Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats
-
17597696 1:CAS:528:DC%2BD2sXpvFWlsb0%3D 10.1038/sj.ki.5002408
-
Krebs C, Hamming I, Sadaghiani S, Steinmetz OM, Meyer-Schwesinger C, Fehr S, Stahl RA, Garrelds IM, Danser AHJ, van Goor H, Contrepas A, Nguyen G, Wenzel U (2007) Antihypertensive therapy upregulates renin and (pro)renin receptor in the clipped kidney of Goldblatt hypertensive rats. Kidney Int 72:725-730
-
(2007)
Kidney Int
, vol.72
, pp. 725-730
-
-
Krebs, C.1
Hamming, I.2
Sadaghiani, S.3
Steinmetz, O.M.4
Meyer-Schwesinger, C.5
Fehr, S.6
Stahl, R.A.7
Garrelds, I.M.8
Danser, A.H.J.9
Van Goor, H.10
Contrepas, A.11
Nguyen, G.12
Wenzel, U.13
-
55
-
-
42649143024
-
Circulating versus tissue renin-angiotensin system: On the origin of (pro)renin
-
18474177 1:CAS:528:DC%2BD1cXnslGrs70%3D 10.1007/s11906-008-0022-1
-
Krop M, Danser AHJ (2008) Circulating versus tissue renin-angiotensin system: on the origin of (pro)renin. Curr Hypertens Rep 10:112-118
-
(2008)
Curr Hypertens Rep
, vol.10
, pp. 112-118
-
-
Krop, M.1
Danser, A.H.J.2
-
56
-
-
42649088714
-
Renin and prorenin disappearance in humans post-nephrectomy: Evidence for binding?
-
18508487 1:CAS:528:DC%2BD1cXnsVKqur8%3D
-
Krop M, de Bruyn JHB, Derkx FHM, Danser AHJ (2008) Renin and prorenin disappearance in humans post-nephrectomy: evidence for binding? Front Biosci 13:3931-3939
-
(2008)
Front Biosci
, vol.13
, pp. 3931-3939
-
-
Krop, M.1
De Bruyn, J.H.B.2
Derkx, F.H.M.3
Danser, A.H.J.4
-
57
-
-
57449100853
-
Aliskiren accumulates in renin secretory granules and binds plasma prorenin
-
18981317 1:CAS:528:DC%2BD1cXhsVWrt7jI 10.1161/HYPERTENSIONAHA.108.123042
-
Krop M, Garrelds IM, de Bruin RJA, van Gool JMG, Fisher ND, Hollenberg NK, Danser AHJ (2008) Aliskiren accumulates in renin secretory granules and binds plasma prorenin. Hypertension 52:1076-1083
-
(2008)
Hypertension
, vol.52
, pp. 1076-1083
-
-
Krop, M.1
Garrelds, I.M.2
De Bruin, R.J.A.3
Van Gool, J.M.G.4
Fisher, N.D.5
Hollenberg, N.K.6
Danser, A.H.J.7
-
58
-
-
80054095029
-
Evaluation of a direct prorenin assay making use of a monoclonal antibody directed against residues 32-39 of the prosegment
-
21881521 1:CAS:528:DC%2BC3MXht12rsLbP 10.1097/HJH.0b013e32834b1978
-
Krop M, van Gool JMG, Day D, Hollenberg NK, Danser AHJ (2011) Evaluation of a direct prorenin assay making use of a monoclonal antibody directed against residues 32-39 of the prosegment. J Hypertens 29:2138-2146
-
(2011)
J Hypertens
, vol.29
, pp. 2138-2146
-
-
Krop, M.1
Van Gool, J.M.G.2
Day, D.3
Hollenberg, N.K.4
Danser, A.H.J.5
-
59
-
-
79952547045
-
A specific binding site for the prorenin propart peptide Arg10-Arg20 does not occur on human endothelial cells
-
20826507 1:CAS:528:DC%2BC3MXlvFWmtb4%3D 10.1177/1470320310370610
-
Leckie BJ, Bottrill AR (2011) A specific binding site for the prorenin propart peptide Arg10-Arg20 does not occur on human endothelial cells. J Renin Angiotensin Aldosterone Syst 12:36-41
-
(2011)
J Renin Angiotensin Aldosterone Syst
, vol.12
, pp. 36-41
-
-
Leckie, B.J.1
Bottrill, A.R.2
-
60
-
-
0025309920
-
Infusion of recombinant human prorenin into rhesus monkeys. Effects on hemodynamics, renin-angiotensin-aldosterone axis and plasma testosterone
-
2189442 1:CAS:528:DyaK3MXitVSgsLc%3D
-
Lenz T, Sealey JE, Lappe RW, Carilli C, Oshiro GT, Baxter JD, Laragh JH (1990) Infusion of recombinant human prorenin into rhesus monkeys. Effects on hemodynamics, renin-angiotensin-aldosterone axis and plasma testosterone. Am J Hypertens 3:257-261
-
(1990)
Am J Hypertens
, vol.3
, pp. 257-261
-
-
Lenz, T.1
Sealey, J.E.2
Lappe, R.W.3
Carilli, C.4
Oshiro, G.T.5
Baxter, J.D.6
Laragh, J.H.7
-
61
-
-
0032748995
-
Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification
-
10581033 1:CAS:528:DyaK1MXnvFOktbc%3D 10.1038/70563
-
Li YP, Chen W, Liang Y, Li E, Stashenko P (1999) Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification. Nat Genet 23:447-451
-
(1999)
Nat Genet
, vol.23
, pp. 447-451
-
-
Li, Y.P.1
Chen, W.2
Liang, Y.3
Li, E.4
Stashenko, P.5
-
62
-
-
79952759673
-
Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway
-
21252698 1:CAS:528:DC%2BC3MXivFWisr4%3D 10.1097/HJH.0b013e328343c62b
-
Liu G, Hitomi H, Hosomi N, Shibayama Y, Nakano D, Kiyomoto H, Ma H, Yamaji Y, Kohno M, Ichihara A, Itoh H, Nishiyama A (2011) Prorenin induces vascular smooth muscle cell proliferation and hypertrophy via epidermal growth factor receptor-mediated extracellular signal-regulated kinase and Akt activation pathway. J Hypertens 29:696-705
-
(2011)
J Hypertens
, vol.29
, pp. 696-705
-
-
Liu, G.1
Hitomi, H.2
Hosomi, N.3
Shibayama, Y.4
Nakano, D.5
Kiyomoto, H.6
Ma, H.7
Yamaji, Y.8
Kohno, M.9
Ichihara, A.10
Itoh, H.11
Nishiyama, A.12
-
63
-
-
84873059054
-
Prorenin stimulates vacuolar H + -ATPase activity in collecting duct cells via the (pro)renin receptor
-
10.1161/HYPERTENSIONAHA.110.168252 1:CAS:528:DC%2BC3MXptFCks7w%3D
-
Lu X, Danser AHJ, Meima ME (2011) Prorenin stimulates vacuolar H + -ATPase activity in collecting duct cells via the (pro)renin receptor. Hypertension 58:e182
-
(2011)
Hypertension
, vol.58
, pp. 182
-
-
Lu, X.1
Danser, A.H.J.2
Meima, M.E.3
-
64
-
-
0032079560
-
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules
-
9556572 1:CAS:528:DyaK1cXjtFGkt7c%3D 10.1074/jbc.273.18.10939
-
Ludwig J, Kerscher S, Brandt U, Pfeiffer K, Getlawi F, Apps DK, Schagger H (1998) Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. J Biol Chem 273:10939-10947
-
(1998)
J Biol Chem
, vol.273
, pp. 10939-10947
-
-
Ludwig, J.1
Kerscher, S.2
Brandt, U.3
Pfeiffer, K.4
Getlawi, F.5
Apps, D.K.6
Schagger, H.7
-
65
-
-
0021889169
-
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
-
3887168 1:STN:280:DyaL2M7ovVWntw%3D%3D 10.1056/NEJM198505303122202
-
Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M (1985) Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications. N Engl J Med 312:1412-1417
-
(1985)
N Engl J Med
, vol.312
, pp. 1412-1417
-
-
Luetscher, J.A.1
Kraemer, F.B.2
Wilson, D.M.3
Schwartz, H.C.4
Bryer-Ash, M.5
-
66
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
19619488 1:CAS:528:DC%2BD1MXpsV2msb8%3D 10.1016/j.devcel.2009.06.016
-
MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17:9-26
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
67
-
-
77649171183
-
(Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation
-
19769609 1:CAS:528:DC%2BC3cXjslemsLg%3D 10.1111/j.1440-1681.2009.05292.x
-
Matavelli LC, Huang J, Siragy HM (2010) (Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation. Clin Exp Pharmacol Physiol 37:277-282
-
(2010)
Clin Exp Pharmacol Physiol
, vol.37
, pp. 277-282
-
-
Matavelli, L.C.1
Huang, J.2
Siragy, H.M.3
-
68
-
-
82655173699
-
The prorenin receptor: What's in a name
-
22052050 1:CAS:528:DC%2BC38XitF2itQ%3D%3D 10.1681/ASN.2011100981
-
Meima ME, Danser AHJ (2011) The prorenin receptor: what's in a name. J Am Soc Nephrol 22:2141-2143
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 2141-2143
-
-
Meima, M.E.1
Danser, A.H.J.2
-
69
-
-
67049100691
-
Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies
-
19364992 1:CAS:528:DC%2BD1MXlslCit78%3D 10.1161/HYPERTENSIONAHA.108. 115444
-
Mercure C, Prescott G, Lacombe MJ, Silversides DW, Reudelhuber TL (2009) Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies. Hypertension 53:1062-1069
-
(2009)
Hypertension
, vol.53
, pp. 1062-1069
-
-
Mercure, C.1
Prescott, G.2
Lacombe, M.J.3
Silversides, D.W.4
Reudelhuber, T.L.5
-
70
-
-
77951111806
-
Renoprotective effects of mineralocorticoid receptor blockade in heminephrectomized (pro)renin receptor transgenic rats
-
20082625 1:CAS:528:DC%2BC3cXmtVWgtLY%3D 10.1111/j.1440-1681.2010.05360.x
-
Mizuguchi Y, Ichihara A, Seki Y, Sakoda M, Kurauchi-Mito A, Narita T, Kinouchi K, Bokuda K, Itoh H (2010) Renoprotective effects of mineralocorticoid receptor blockade in heminephrectomized (pro)renin receptor transgenic rats. Clin Exp Pharmacol Physiol 37:569-573
-
(2010)
Clin Exp Pharmacol Physiol
, vol.37
, pp. 569-573
-
-
Mizuguchi, Y.1
Ichihara, A.2
Seki, Y.3
Sakoda, M.4
Kurauchi-Mito, A.5
Narita, T.6
Kinouchi, K.7
Bokuda, K.8
Itoh, H.9
-
71
-
-
0345826111
-
ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells
-
14600156 1:CAS:528:DC%2BD2cXisF2mug%3D%3D 10.1074/jbc.M304907200
-
Mukhin YV, Garnovskaya MN, Ullian ME, Raymond JR (2004) ERK is regulated by sodium-proton exchanger in rat aortic vascular smooth muscle cells. J Biol Chem 279:1845-1852
-
(2004)
J Biol Chem
, vol.279
, pp. 1845-1852
-
-
Mukhin, Y.V.1
Garnovskaya, M.N.2
Ullian, M.E.3
Raymond, J.R.4
-
72
-
-
33750600468
-
Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system
-
16865234 1:CAS:528:DC%2BD28XptVWqtr4%3D
-
Nabi AH, Kageshima A, Uddin MN, Nakagawa T, Park EY, Suzuki F (2006) Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 18:483-488
-
(2006)
Int J Mol Med
, vol.18
, pp. 483-488
-
-
Nabi, A.H.1
Kageshima, A.2
Uddin, M.N.3
Nakagawa, T.4
Park, E.Y.5
Suzuki, F.6
-
73
-
-
67649534504
-
'Decoy peptide' region (RIFLKRMPSI) of prorenin prosegment plays a crucial role in prorenin binding to the (pro)renin receptor
-
19513539 1:CAS:528:DC%2BD1MXos1WhurY%3D
-
Nabi AH, Biswas KB, Nakagawa T, Ichihara A, Inagami T, Suzuki F (2009) 'Decoy peptide' region (RIFLKRMPSI) of prorenin prosegment plays a crucial role in prorenin binding to the (pro)renin receptor. Int J Mol Med 24:83-89
-
(2009)
Int J Mol Med
, vol.24
, pp. 83-89
-
-
Nabi, A.H.1
Biswas, K.B.2
Nakagawa, T.3
Ichihara, A.4
Inagami, T.5
Suzuki, F.6
-
74
-
-
73049099445
-
Prorenin has high affinity multiple binding sites for (pro)renin receptor
-
19733264 1:CAS:528:DC%2BD1MXht1Ggt77O 10.1016/j.bbapap.2009.08.024
-
Nabi AH, Biswas KB, Nakagawa T, Ichihara A, Inagami T, Suzuki F (2009) Prorenin has high affinity multiple binding sites for (pro)renin receptor. Biochim Biophys Acta 1794:1838-1847
-
(2009)
Biochim Biophys Acta
, vol.1794
, pp. 1838-1847
-
-
Nabi, A.H.1
Biswas, K.B.2
Nakagawa, T.3
Ichihara, A.4
Inagami, T.5
Suzuki, F.6
-
75
-
-
35148898712
-
Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway
-
17724226 10.1167/iovs.06-1473
-
Nagai N, Izumi-Nagai K, Oike Y, Koto T, Satofuka S, Ozawa Y, Yamashiro K, Inoue M, Tsubota K, Umezawa K, Ishida S (2007) Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway. Invest Ophthalmol Vis Sci 48:4342-4350
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 4342-4350
-
-
Nagai, N.1
Izumi-Nagai, K.2
Oike, Y.3
Koto, T.4
Satofuka, S.5
Ozawa, Y.6
Yamashiro, K.7
Inoue, M.8
Tsubota, K.9
Umezawa, K.10
Ishida, S.11
-
76
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
-
12045255 1:CAS:528:DC%2BD38XktlWlu78%3D
-
Nguyen G, Delarue F, Burcklé CA, Bouzhir L, Giller T, Sraer JD (2002) Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109:1417-1427
-
(2002)
J Clin Invest
, vol.109
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burcklé, C.A.3
Bouzhir, L.4
Giller, T.5
Sraer, J.D.6
-
77
-
-
59449087945
-
The vacuolar-ATPase complex regulates retinoblast proliferation and survival, photoreceptor morphogenesis, and pigmentation in the zebrafish eye
-
18836173 10.1167/iovs.08-2743
-
Nuckels RJ, Ng A, Darland T, Gross JM (2009) The vacuolar-ATPase complex regulates retinoblast proliferation and survival, photoreceptor morphogenesis, and pigmentation in the zebrafish eye. Invest Ophthalmol Vis Sci 50:893-905
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 893-905
-
-
Nuckels, R.J.1
Ng, A.2
Darland, T.3
Gross, J.M.4
-
78
-
-
79953758074
-
Wnt/beta-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells
-
21494638 1:CAS:528:DC%2BC3MXkvFKjtbs%3D 10.1371/journal.pone.0018562
-
Nunez F, Bravo S, Cruzat F, Montecino M, De Ferrari GV (2011) Wnt/beta-catenin signaling enhances cyclooxygenase-2 (COX2) transcriptional activity in gastric cancer cells. PLoS One 6:e18562
-
(2011)
PLoS One
, vol.6
, pp. 18562
-
-
Nunez, F.1
Bravo, S.2
Cruzat, F.3
Montecino, M.4
De Ferrari, G.V.5
-
79
-
-
82655181486
-
Prorenin receptor is essential for normal podocyte structure and function
-
22052048 1:CAS:528:DC%2BC38XitF2hug%3D%3D 10.1681/ASN.2011020202
-
Oshima Y, Kinouchi K, Ichihara A, Sakoda M, Kurauchi-Mito A, Bokuda K, Narita T, Kurosawa H, Sun-Wada GH, Wada Y, Yamada T, Takemoto M, Saleem MA, Quaggin SE, Itoh H (2011) Prorenin receptor is essential for normal podocyte structure and function. J Am Soc Nephrol 22:2203-2212
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 2203-2212
-
-
Oshima, Y.1
Kinouchi, K.2
Ichihara, A.3
Sakoda, M.4
Kurauchi-Mito, A.5
Bokuda, K.6
Narita, T.7
Kurosawa, H.8
Sun-Wada, G.H.9
Wada, Y.10
Yamada, T.11
Takemoto, M.12
Saleem, M.A.13
Quaggin, S.E.14
Itoh, H.15
-
80
-
-
79955886634
-
Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men
-
21346687 1:CAS:528:DC%2BC3MXlslyktLc%3D 10.1097/FPC.0b013e328344cdd2
-
Ott C, Schneider MP, Delles C, Schlaich MP, Hilgers KF, Schmieder RE (2011) Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men. Pharmacogenet Genomics 21:347-349
-
(2011)
Pharmacogenet Genomics
, vol.21
, pp. 347-349
-
-
Ott, C.1
Schneider, M.P.2
Delles, C.3
Schlaich, M.P.4
Hilgers, K.F.5
Schmieder, R.E.6
-
81
-
-
37349054998
-
Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: Absence of prorenin-induced glomerulosclerosis
-
18090546 1:CAS:528:DC%2BD2sXhsVCjsrjI 10.1097/HJH.0b013e3282f0ab66
-
Peters B, Grisk O, Becher B, Wanka H, Kuttler B, Ludemann J, Lorenz G, Rettig R, Mullins JJ, Peters J (2008) Dose-dependent titration of prorenin and blood pressure in Cyp1a1ren-2 transgenic rats: absence of prorenin-induced glomerulosclerosis. J Hypertens 26:102-109
-
(2008)
J Hypertens
, vol.26
, pp. 102-109
-
-
Peters, B.1
Grisk, O.2
Becher, B.3
Wanka, H.4
Kuttler, B.5
Ludemann, J.6
Lorenz, G.7
Rettig, R.8
Mullins, J.J.9
Peters, J.10
-
82
-
-
3543026852
-
Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats
-
15226276 1:CAS:528:DC%2BD2cXlvVKlsLw%3D 10.1161/01.HYP.0000135678.20725. 54
-
Prieto-Carrasquero MC, Harrison-Bernard LM, Kobori H, Ozawa Y, Hering-Smith KS, Hamm LL, Navar LG (2004) Enhancement of collecting duct renin in angiotensin II-dependent hypertensive rats. Hypertension 44:223-229
-
(2004)
Hypertension
, vol.44
, pp. 223-229
-
-
Prieto-Carrasquero, M.C.1
Harrison-Bernard, L.M.2
Kobori, H.3
Ozawa, Y.4
Hering-Smith, K.S.5
Hamm, L.L.6
Navar, L.G.7
-
83
-
-
20244369597
-
A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor
-
15746149 1:CAS:528:DC%2BD2MXjtlensrw%3D 10.1093/hmg/ddi094
-
Ramser J, Abidi FE, Burcklé CA, Lenski C, Toriello H, Wen G, Lubs HA, Engert S, Stevenson RE, Meindl A, Schwartz CE, Nguyen G (2005) A unique exonic splice enhancer mutation in a family with X-linked mental retardation and epilepsy points to a novel role of the renin receptor. Hum Mol Genet 14:1019-1027
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1019-1027
-
-
Ramser, J.1
Abidi, F.E.2
Burcklé, C.A.3
Lenski, C.4
Toriello, H.5
Wen, G.6
Lubs, H.A.7
Engert, S.8
Stevenson, R.E.9
Meindl, A.10
Schwartz, C.E.11
Nguyen, G.12
-
84
-
-
82655181484
-
Prorenin receptor is essential for podocyte autophagy and survival
-
22034640 1:CAS:528:DC%2BC38XitF2htQ%3D%3D 10.1681/ASN.2011020200
-
Riediger F, Quack I, Qadri F, Hartleben B, Park JK, Potthoff SA, Sohn D, Sihn G, Rousselle A, Fokuhl V, Maschke U, Purfurst B, Schneider W, Rump LC, Luft FC, Dechend R, Bader M, Huber TB, Nguyen G, Müller DN (2011) Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol 22:2193-2202
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 2193-2202
-
-
Riediger, F.1
Quack, I.2
Qadri, F.3
Hartleben, B.4
Park, J.K.5
Potthoff, S.A.6
Sohn, D.7
Sihn, G.8
Rousselle, A.9
Fokuhl, V.10
Maschke, U.11
Purfurst, B.12
Schneider, W.13
Rump, L.C.14
Luft, F.C.15
Dechend, R.16
Bader, M.17
Huber, T.B.18
Nguyen, G.19
Müller, D.N.20
more..
-
85
-
-
0036180613
-
Prorenin-induced myocyte proliferation: No role for intracellular angiotensin II
-
11882610 1:CAS:528:DC%2BD38Xhs1Wlu7c%3D 10.1161/hy0202.103002
-
Saris JJ, van den Eijnden MM, Lamers JM, Saxena PR, Schalekamp MADH, Danser AHJ (2002) Prorenin-induced myocyte proliferation: no role for intracellular angiotensin II. Hypertension 39:573-577
-
(2002)
Hypertension
, vol.39
, pp. 573-577
-
-
Saris, J.J.1
Van Den Eijnden, M.M.2
Lamers, J.M.3
Saxena, P.R.4
Schalekamp, M.5
Danser, A.H.J.6
-
86
-
-
33750266798
-
Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II
-
16940215 1:CAS:528:DC%2BD28XpsFOrsL4%3D 10.1161/01.HYP.0000240064.19301. 1b
-
Saris JJ, t Hoen PA, Garrelds IM, Dekkers DHW, den Dunnen JT, Lamers JMJ, Danser AHJ (2006) Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II. Hypertension 48:564-571
-
(2006)
Hypertension
, vol.48
, pp. 564-571
-
-
Saris, J.J.1
Hoen, P.A.T.2
Garrelds, I.M.3
Dekkers, D.H.W.4
Den Dunnen, J.T.5
Lamers, J.M.J.6
Danser, A.H.J.7
-
87
-
-
67650236573
-
(Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation
-
19389828 1:CAS:528:DC%2BD1MXos1Cqu7w%3D 10.2337/db08-0254
-
Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S (2009) (Pro)renin receptor-mediated signal transduction and tissue renin-angiotensin system contribute to diabetes-induced retinal inflammation. Diabetes 58:1625-1633
-
(2009)
Diabetes
, vol.58
, pp. 1625-1633
-
-
Satofuka, S.1
Ichihara, A.2
Nagai, N.3
Noda, K.4
Ozawa, Y.5
Fukamizu, A.6
Tsubota, K.7
Itoh, H.8
Oike, Y.9
Ishida, S.10
-
88
-
-
42049108426
-
Newly developed renin and prorenin assays and the clinical evaluation of renin inhibitors
-
18398335 1:CAS:528:DC%2BD1cXktl2rtLY%3D 10.1097/HJH.0b013e3282f6a671
-
Schalekamp MADH, Derkx FHM, Deinum J, Danser AHJ (2008) Newly developed renin and prorenin assays and the clinical evaluation of renin inhibitors. J Hypertens 26:928-937
-
(2008)
J Hypertens
, vol.26
, pp. 928-937
-
-
Schalekamp, M.1
Derkx, F.H.M.2
Deinum, J.3
Danser, A.H.J.4
-
89
-
-
33845608395
-
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
-
17082479 1:CAS:528:DC%2BD28Xht1Ohu7%2FM 10.1161/01.RES.0000251700.00994. 0d
-
Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H (2006) A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 99:1355-1366
-
(2006)
Circ Res
, vol.99
, pp. 1355-1366
-
-
Schefe, J.H.1
Menk, M.2
Reinemund, J.3
Effertz, K.4
Hobbs, R.M.5
Pandolfi, P.P.6
Ruiz, P.7
Unger, T.8
Funke-Kaiser, H.9
-
90
-
-
56749090710
-
Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren
-
18698213 1:CAS:528:DC%2BD1cXpvFynsLg%3D 10.1097/HJH.0b013e3283060f2e
-
Schefe JH, Neumann C, Goebel M, Danser AHJ, Kirsch S, Gust R, Kintscher U, Unger T, Funke-Kaiser H (2008) Prorenin engages the (pro)renin receptor like renin and both ligand activities are unopposed by aliskiren. J Hypertens 26:1787-1794
-
(2008)
J Hypertens
, vol.26
, pp. 1787-1794
-
-
Schefe, J.H.1
Neumann, C.2
Goebel, M.3
Danser, A.H.J.4
Kirsch, S.5
Gust, R.6
Kintscher, U.7
Unger, T.8
Funke-Kaiser, H.9
-
91
-
-
35348960363
-
Renin release
-
17928544 1:CAS:528:DC%2BD2sXhtlelsbnN 10.1152/physiol.00024.2007
-
Schweda F, Friis U, Wagner C, Skott O, Kurtz A (2007) Renin release. Physiology 22:310-319
-
(2007)
Physiology
, vol.22
, pp. 310-319
-
-
Schweda, F.1
Friis, U.2
Wagner, C.3
Skott, O.4
Kurtz, A.5
-
92
-
-
77957375156
-
Add-on blockade of (pro)renin receptor in imidapril-treated diabetic SHRsp
-
10.2741/E156
-
Seki Y, Ichihara A, Mizuguchi Y, Sakoda M, Kurauchi-Mito A, Narita T, Kinouchi K, Bokuda K, Itoh H (2010) Add-on blockade of (pro)renin receptor in imidapril-treated diabetic SHRsp. Front Biosci (Elite Ed) 2:972-979
-
(2010)
Front Biosci (Elite Ed)
, vol.2
, pp. 972-979
-
-
Seki, Y.1
Ichihara, A.2
Mizuguchi, Y.3
Sakoda, M.4
Kurauchi-Mito, A.5
Narita, T.6
Kinouchi, K.7
Bokuda, K.8
Itoh, H.9
-
93
-
-
77954756914
-
Physiology of the (pro)renin receptor: Wnt of change?
-
20505655 1:CAS:528:DC%2BC3cXovFKgtL0%3D 10.1038/ki.2010.151
-
Sihn G, Rousselle A, Vilianovitch L, Burcklé CA, Bader M (2010) Physiology of the (pro)renin receptor: Wnt of change? Kidney Int 78:246-256
-
(2010)
Kidney Int
, vol.78
, pp. 246-256
-
-
Sihn, G.1
Rousselle, A.2
Vilianovitch, L.3
Burcklé, C.A.4
Bader, M.5
-
94
-
-
54049106595
-
Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet
-
18621861 1:CAS:528:DC%2BD1cXhtFCgt7fJ 10.1152/ajpheart.00055.2008
-
Susic D, Zhou X, Frohlich ED, Lippton H, Knight M (2008) Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet. Am J Physiol Heart Circ Physiol 295:H1117-H1121
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Susic, D.1
Zhou, X.2
Frohlich, E.D.3
Lippton, H.4
Knight, M.5
-
95
-
-
0037591344
-
Human prorenin has «gate and handle» regions for its non-proteolytic activation
-
12684512 1:CAS:528:DC%2BD3sXksF2ju7s%3D 10.1074/jbc.M302579200
-
Suzuki F, Hayakawa M, Nakagawa T, Nasir UM, Ebihara A, Iwasawa A, Ishida Y, Nakamura Y, Murakami K (2003) Human prorenin has «gate and handle» regions for its non-proteolytic activation. J Biol Chem 278:22217-22222
-
(2003)
J Biol Chem
, vol.278
, pp. 22217-22222
-
-
Suzuki, F.1
Hayakawa, M.2
Nakagawa, T.3
Nasir, U.M.4
Ebihara, A.5
Iwasawa, A.6
Ishida, Y.7
Nakamura, Y.8
Murakami, K.9
-
96
-
-
34447272037
-
Regression of nephropathy developed in diabetes by (Pro)renin receptor blockade
-
17538189 1:CAS:528:DC%2BD2sXotlWntbo%3D 10.1681/ASN.2006080820
-
Takahashi H, Ichihara A, Kaneshiro Y, Inomata K, Sakoda M, Takemitsu T, Nishiyama A, Itoh H (2007) Regression of nephropathy developed in diabetes by (Pro)renin receptor blockade. J Am Soc Nephrol 18:2054-2061
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2054-2061
-
-
Takahashi, H.1
Ichihara, A.2
Kaneshiro, Y.3
Inomata, K.4
Sakoda, M.5
Takemitsu, T.6
Nishiyama, A.7
Itoh, H.8
-
97
-
-
77952543500
-
Expression of (pro)renin receptor in human kidneys with end-stage kidney disease due to diabetic nephropathy
-
20385187 1:CAS:528:DC%2BC3cXmslWjtLY%3D 10.1016/j.peptides.2010.04.003
-
Takahashi K, Yamamoto H, Hirose T, Hiraishi K, Shoji I, Shibasaki A, Kato I, Kaneko K, Sasano H, Satoh F, Totsune K (2010) Expression of (pro)renin receptor in human kidneys with end-stage kidney disease due to diabetic nephropathy. Peptides 31:1405-1408
-
(2010)
Peptides
, vol.31
, pp. 1405-1408
-
-
Takahashi, K.1
Yamamoto, H.2
Hirose, T.3
Hiraishi, K.4
Shoji, I.5
Shibasaki, A.6
Kato, I.7
Kaneko, K.8
Sasano, H.9
Satoh, F.10
Totsune, K.11
-
98
-
-
0018107601
-
Role of persistent vascular renin after bilateral nephrectomy in Goldblatt-two kidney hypertension
-
282058 1:STN:280:DyaE1M%2FosV2nuw%3D%3D
-
Thurston H, Hurst BC, Bing RF, Swales JD (1978) Role of persistent vascular renin after bilateral nephrectomy in Goldblatt-two kidney hypertension. Clin Sci Mol Med Suppl 4:23s-26s
-
(1978)
Clin Sci Mol Med Suppl
, vol.4
-
-
Thurston, H.1
Hurst, B.C.2
Bing, R.F.3
Swales, J.D.4
-
99
-
-
77953255215
-
Regulation and isoform function of the V-ATPases
-
20450191 1:CAS:528:DC%2BC3cXmt1Krt7Y%3D 10.1021/bi100397s
-
Toei M, Saum R, Forgac M (2010) Regulation and isoform function of the V-ATPases. Biochemistry 49:4715-4723
-
(2010)
Biochemistry
, vol.49
, pp. 4715-4723
-
-
Toei, M.1
Saum, R.2
Forgac, M.3
-
100
-
-
0035715143
-
Prorenin accumulation and activation in human endothelial cells: Importance of mannose 6-phosphate receptors
-
11397696 10.1161/01.ATV.21.6.911
-
van den Eijnden MM, Saris JJ, de Bruin RJA, de Wit E, Sluiter W, Reudelhuber TL, Schalekamp MADH, Derkx FHM, Danser AHJ (2001) Prorenin accumulation and activation in human endothelial cells: importance of mannose 6-phosphate receptors. Arterioscler Thromb Vasc Biol 21:911-916
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 911-916
-
-
Van Den Eijnden, M.M.1
Saris, J.J.2
De Bruin, R.J.A.3
De Wit, E.4
Sluiter, W.5
Reudelhuber, T.L.6
Schalekamp, M.7
Derkx, F.H.M.8
Danser, A.H.J.9
-
101
-
-
79953196418
-
Handle region peptide counteracts the beneficial effects of the renin inhibitor aliskiren in spontaneously hypertensive rats
-
21321303 10.1161/HYPERTENSIONAHA.110.169060 1:CAS:528: DC%2BC3MXjt1Gnsb4%3D
-
van Esch JHM, van Veghel R, Garrelds IM, Leijten F, Bouhuizen AM, Danser AHJ (2011) Handle region peptide counteracts the beneficial effects of the renin inhibitor aliskiren in spontaneously hypertensive rats. Hypertension 57:852-858
-
(2011)
Hypertension
, vol.57
, pp. 852-858
-
-
Van Esch, J.H.M.1
Van Veghel, R.2
Garrelds, I.M.3
Leijten, F.4
Bouhuizen, A.M.5
Danser, A.H.J.6
-
102
-
-
0029858320
-
Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver
-
8903314 10.1172/JCI119000
-
Véniant M, Menard J, Bruneval P, Morley S, Gonzales MF, Mullins J (1996) Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest 98:1966-1970
-
(1996)
J Clin Invest
, vol.98
, pp. 1966-1970
-
-
Véniant, M.1
Menard, J.2
Bruneval, P.3
Morley, S.4
Gonzales, M.F.5
Mullins, J.6
-
104
-
-
81155150123
-
Canonical Wnt/beta-catenin signaling mediates transforming growth factor-beta1-driven podocyte injury and proteinuria
-
Wang D, Dai C, Li Y, Liu Y (2011) Canonical Wnt/beta-catenin signaling mediates transforming growth factor-beta1-driven podocyte injury and proteinuria. Kidney Int 80:1159-1169
-
(2011)
Kidney Int
, vol.80
, pp. 1159-1169
-
-
Wang, D.1
Dai, C.2
Li, Y.3
Liu, Y.4
-
105
-
-
79955616015
-
The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space
-
21270819 1:CAS:528:DC%2BC3MXlsFKitL8%3D 10.1038/hr.2010.284
-
Yoshikawa A, Aizaki Y, Kusano K, Kishi F, Susumu T, Iida S, Ishiura S, Nishimura S, Shichiri M, Senbonmatsu T (2011) The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space. Hypertens Res 34:599-605
-
(2011)
Hypertens Res
, vol.34
, pp. 599-605
-
-
Yoshikawa, A.1
Aizaki, Y.2
Kusano, K.3
Kishi, F.4
Susumu, T.5
Iida, S.6
Ishiura, S.7
Nishimura, S.8
Shichiri, M.9
Senbonmatsu, T.10
-
106
-
-
56049114004
-
Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells
-
18664599 1:CAS:528:DC%2BD1cXht1ymtb%2FI 10.1152/ajpendo.90264.2008
-
Zhang J, Noble NA, Border WA, Owens RT, Huang Y (2008) Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 295:E810-819
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. 810-819
-
-
Zhang, J.1
Noble, N.A.2
Border, W.A.3
Owens, R.T.4
Huang, Y.5
-
107
-
-
79955024105
-
Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein
-
21420935 1:CAS:528:DC%2BC3MXltFequ7k%3D 10.1016/j.bbrc.2011.03.074
-
Zhang Y, Gao X, Michael Garavito R (2011) Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein. Biochem Biophys Res Commun 407:674-679
-
(2011)
Biochem Biophys Res Commun
, vol.407
, pp. 674-679
-
-
Zhang, Y.1
Gao, X.2
Michael Garavito, R.3
-
108
-
-
80053344229
-
Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis
-
21795644 1:CAS:528:DC%2BC3MXhtlertrbL 10.1152/ajprenal.00271.2011
-
Zhang J, Gu C, Noble NA, Border WA, Huang Y (2011) Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis. Am J Physiol Renal Physiol 301:F723-732
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. 723-732
-
-
Zhang, J.1
Gu, C.2
Noble, N.A.3
Border, W.A.4
Huang, Y.5
-
109
-
-
78149267757
-
A redox switch in angiotensinogen modulates angiotensin release
-
20927107 1:CAS:528:DC%2BC3cXht1Gju7rJ 10.1038/nature09505
-
Zhou A, Carrell RW, Murphy MP, Wei Z, Yan Y, Stanley PL, Stein PE, Broughton Pipkin F, Read RJ (2010) A redox switch in angiotensinogen modulates angiotensin release. Nature 468:108-111
-
(2010)
Nature
, vol.468
, pp. 108-111
-
-
Zhou, A.1
Carrell, R.W.2
Murphy, M.P.3
Wei, Z.4
Yan, Y.5
Stanley, P.L.6
Stein, P.E.7
Broughton Pipkin, F.8
Read, R.J.9
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