Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men

Pharmacogenetics and Genomics

Volumn 21, Issue 6, 2011, Pages 347-349

  Ott, Christian ^a   Schneider, Markus P ^a   Delles, Christian ^a   Schlaich, Markus P ^a   Hilgers, Karl F ^a   Schmieder, Roland E ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

(pro)renin receptor; aldosterone; blood pressure; polymorphism; renal haemodynamics

Indexed keywords

ALDOSTERONE; PRORENIN RECEPTOR;

ADULT; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ALLELE; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; BLOOD PRESSURE REGULATION; CAUCASIAN; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HEART RATE; HUMAN; JAPANESE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PRORENIN RECEPTOR GENE; RECEPTOR GENE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE;

EID: 79955886634     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e328344cdd2     Document Type: Article

References (9)

1. Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin ii production and cellular responses to renin. J Clin Invest 2002; 109:1417-1427. (Pubitemid 34596167)
2. Nguyen G, Muller DN. The biology of the (pro)renin receptor. J Am Soc Nephrol 2010; 21:18-23.
3. Burckle CA, Jan Danser AH, Muller DN, Garrelds IM, Gasc JM, Popova E, et al. Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension 2006; 47:552-556. (Pubitemid 43843874)
4. Hirose T, Hashimoto M, Totsune K, Metoki H, Asayama K, Kikuya M, et al. Association of (pro)renin receptor gene polymorphism with blood pressure in Japanese men: the Ohasama study. Am J Hypertens 2009; 22:294-299.
5. Ott C, Schlaich MP, Schmidt BM, Titze SI, Schaufele T, Schmieder RE. Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia. Atherosclerosis 2008; 196:704-711.
6. Schmieder RE, Langenfeld MR, Friedrich A, Schobel HP, Gatzka CD, Weihprecht H. Angiotensin ii related to sodium excretion modulates left ventricular structure in human essential hypertension. Circulation 1996; 94:1304-1309. (Pubitemid 26307257)
7. Padmanabhan S, Menni C, Lee WK, Laing S, Brambilla P, Sega R, et al. The effects of sex and method of blood pressure measurement on genetic associations with blood pressure in the PAMELA study. J Hypertens 2010; 28:465-477.
8. Mizuguchi Y, Ichihara A, Seki Y, Sakoda M, Kurauchi-Mito A, Narita T, et al. Renoprotective effects of mineralocorticoid receptor blockade in hemi-nephrectomized (pro)renin-receptor-transgenic rats. Clin Exp Pharmacol Physiol 2010; 37:569-573.
9. Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Nakagawa T, Nishiyama A, et al. Contribution of nonproteolytically activated prorenin in glomeruli to hypertensive renal damage. J Am Soc Nephrol 2006; 17:2495-2503. (Pubitemid 44300965)