The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space

Hypertension Research

Volumn 34, Issue 5, 2011, Pages 599-605

  Yoshikawa, Ayumu ^a   Aizaki, Yoshimi ^a   Kusano, Ken Ichi ^b   Kishi, Fukuko ^b   Susumu, Teruo ^b   Iida, Shinichiro ^c   Ishiura, Shoichi ^d   Nishimura, Shigeyuki ^c   Shichiri, Masayoshi ^e   Senbonmatsu, Takaaki ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b Protein Express   (Japan)

^c SAITAMA MEDICAL UNIVERSITY INTERNATIONAL MEDICAL CENTER   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

(pro)renin receptor; ADAM19; ectodomain shedding; renin angiotensin system

Indexed keywords

FURIN; PRORENIN; PRORENIN RECEPTOR; PROTEIN ADAM19; PROTEINASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; EXTRACELLULAR SPACE; FEMALE; GOLGI COMPLEX; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; NONHUMAN; PLASMA RENIN ACTIVITY; PROTEIN CLEAVAGE; PROTEIN SECRETION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ADAM PROTEINS; ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; EXTRACELLULAR SPACE; GOLGI APPARATUS; HUMANS; MUSCLE, SMOOTH, VASCULAR; PROTEIN TRANSPORT; RECEPTORS, CELL SURFACE;

EID: 79955616015     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2010.284     Document Type: Article

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