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Volumn 300, Issue 6, 2011, Pages

(Pro)renin promotes fibrosis gene expression in HEK cells through a Nox4-dependent mechanism

Author keywords

Kidney; NADPH oxidase; Prorenin receptor

Indexed keywords

FIBRONECTIN; HYDROXYLAMINE; LUCIGENIN; PERINDOPRIL; PLASMINOGEN ACTIVATOR INHIBITOR 1; PRORENIN; PRORENIN RECEPTOR; PROTEIN P47; PROTEIN P67; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; RENIN; SMALL INTERFERING RNA; SUPEROXIDE; TRANSFORMING GROWTH FACTOR BETA;

EID: 79958135759     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00119.2010     Document Type: Article
Times cited : (39)

References (40)
  • 2
    • 0034121853 scopus 로고    scopus 로고
    • Regulation of renin: New evidence from cultured cells and genetically modified mice
    • Bader M, Ganten D. Regulation of renin: new evidence from cultured cells and genetically modified mice. J Mol Med 78: 130-139, 2000.
    • (2000) J Mol Med , vol.78 , pp. 130-139
    • Bader, M.1    Ganten, D.2
  • 4
    • 35848948398 scopus 로고    scopus 로고
    • Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor
    • Batenburg WW, Krop M, Garrelds IM, de Vries R, de Bruin RJ, Burckle CA, Muller DN, Bader M, Nguyen G, Danser AH. Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens 25: 2441-2453, 2007.
    • (2007) J Hypertens , vol.25 , pp. 2441-2453
    • Batenburg, W.W.1    Krop, M.2    Garrelds, I.M.3    de Vries, R.4    de Bruin, R.J.5    Burckle, C.A.6    Muller, D.N.7    Bader, M.8    Nguyen, G.9    Danser, A.H.10
  • 5
    • 53049098763 scopus 로고    scopus 로고
    • Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: Role in mesangial cell hypertrophy and fibronectin expression
    • Block K, Eid A, Griendling KK, Lee DY, Wittrant Y, Gorin Y. Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II: role in mesangial cell hypertrophy and fibronectin expression. J Biol Chem 283: 24061-24076, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 24061-24076
    • Block, K.1    Eid, A.2    Griendling, K.K.3    Lee, D.Y.4    Wittrant, Y.5    Gorin, Y.6
  • 7
    • 0035900676 scopus 로고    scopus 로고
    • Reactive oxygen species are downstream products of TRAF-mediated signal transduction
    • Chandel NS, Schumacker PT, Arch RH. Reactive oxygen species are downstream products of TRAF-mediated signal transduction. J Biol Chem 276: 42728-42736, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 42728-42736
    • Chandel, N.S.1    Schumacker, P.T.2    Arch, R.H.3
  • 8
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factorbeta1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D. NAD(P)H oxidase 4 mediates transforming growth factorbeta1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 97: 900-907, 2005.
    • (2005) Circ Res , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 9
    • 27444447364 scopus 로고    scopus 로고
    • Renin, prorenin and the putative (pro)renin receptor
    • Danser AH, Deinum J. Renin, prorenin and the putative (pro)renin receptor. Hypertension 46: 1069-1076, 2005.
    • (2005) Hypertension , vol.46 , pp. 1069-1076
    • Danser, A.H.1    Deinum, J.2
  • 10
    • 0032787740 scopus 로고    scopus 로고
    • Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus
    • Deinum J, Ronn B, Mathiesen E, Derkx FH, Hop WC, Schalekamp MA. Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus. Diabetologia 42: 1006-1010, 1999.
    • (1999) Diabetologia , vol.42 , pp. 1006-1010
    • Deinum, J.1    Ronn, B.2    Mathiesen, E.3    Derkx, F.H.4    Hop, W.C.5    Schalekamp, M.A.6
  • 11
    • 34548861472 scopus 로고    scopus 로고
    • Oxidative stress-mediated mesangial cell proliferation requires RAC-1/reactive oxygen species production and beta4 integrin expression
    • Dentelli P, Rosso A, Zeoli A, Gambino R, Pegoraro L, Pagano G, Falcioni R, Brizzi MF. Oxidative stress-mediated mesangial cell proliferation requires RAC-1/reactive oxygen species production and beta4 integrin expression. J Biol Chem 282: 26101-26110, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 26101-26110
    • Dentelli, P.1    Rosso, A.2    Zeoli, A.3    Gambino, R.4    Pegoraro, L.5    Pagano, G.6    Falcioni, R.7    Brizzi, M.F.8
  • 12
    • 33847164832 scopus 로고    scopus 로고
    • Production of extracellular superoxide by human lymphoblast cell lines: Comparison of electron spin resonance techniques and cytochrome C reduction assay
    • Dikalov SI, Li W, Mehranpour P, Wang SS, Zafari AM. Production of extracellular superoxide by human lymphoblast cell lines: comparison of electron spin resonance techniques and cytochrome C reduction assay. Biochem Pharmacol 73: 972-980, 2007.
    • (2007) Biochem Pharmacol , vol.73 , pp. 972-980
    • Dikalov, S.I.1    Li, W.2    Mehranpour, P.3    Wang, S.S.4    Zafari, A.M.5
  • 15
  • 16
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • Huang Y, Wongamorntham S, Kasting J, McQuillan D, Owens RT, Yu L, Noble NA, Border W. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 69: 105-113, 2006.
    • (2006) Kidney Int , vol.69 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6    Noble, N.A.7    Border, W.8
  • 21
    • 34347257042 scopus 로고    scopus 로고
    • Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy
    • Lambeth JD. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic Biol Med 43: 332-347, 2007.
    • (2007) Free Radic Biol Med , vol.43 , pp. 332-347
    • Lambeth, J.D.1
  • 22
    • 34250888056 scopus 로고    scopus 로고
    • Regulation of Nox and Duox enzymatic activity and expression
    • Lambeth JD, Kawahara T, Diebold B. Regulation of Nox and Duox enzymatic activity and expression. Free Radic Biol Med 43: 319-331, 2007.
    • (2007) Free Radic Biol Med , vol.43 , pp. 319-331
    • Lambeth, J.D.1    Kawahara, T.2    Diebold, B.3
  • 23
    • 0030989642 scopus 로고    scopus 로고
    • Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production
    • Liochev SI, Fridovich I. Lucigenin (bis-N-methylacridinium) as a mediator of superoxide anion production. Arch Biochem Biophys 337: 115-120, 1997.
    • (1997) Arch Biochem Biophys , vol.337 , pp. 115-120
    • Liochev, S.I.1    Fridovich, I.2
  • 24
    • 0021889169 scopus 로고
    • Increased plasma inactive renin in diabetes mellitus a marker of microvascular complications
    • Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. Increased plasma inactive renin in diabetes mellitus a marker of microvascular complications. N Engl J Med 312: 1412-1417, 1985.
    • (1985) N Engl J Med , vol.312 , pp. 1412-1417
    • Luetscher, J.A.1    Kraemer, F.B.2    Wilson, D.M.3    Schwartz, H.C.4    Bryer-Ash, M.5
  • 25
    • 33750600468 scopus 로고    scopus 로고
    • Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system
    • Nabi AH, Kageshima A, Uddin MN, Nakagawa T, Park EY, Suzuki F. Binding properties of rat prorenin and renin to the recombinant rat renin/prorenin receptor prepared by a baculovirus expression system. Int J Mol Med 18: 483-488, 2006.
    • (2006) Int J Mol Med , vol.18 , pp. 483-488
    • Nabi, A.H.1    Kageshima, A.2    Uddin, M.N.3    Nakagawa, T.4    Park, E.Y.5    Suzuki, F.6
  • 26
    • 4644220247 scopus 로고    scopus 로고
    • Renin/prorenin-receptor biochemistry and functional significance
    • Nguyen G, Burckle CA, Sraer JD. Renin/prorenin-receptor biochemistry and functional significance. Curr Hypertens Rep 6: 129-132, 2004.
    • (2004) Curr Hypertens Rep , vol.6 , pp. 129-132
    • Nguyen, G.1    Burckle, C.A.2    Sraer, J.D.3
  • 27
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 109: 1417-1427, 2002.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 28
    • 30944465223 scopus 로고    scopus 로고
    • Receptor-mediated actions of renin and prorenin
    • Oliver JA. Receptor-mediated actions of renin and prorenin. Kidney Int 69: 13-15, 2006.
    • (2006) Kidney Int , vol.69 , pp. 13-15
    • Oliver, J.A.1
  • 31
    • 33845608395 scopus 로고    scopus 로고
    • A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein
    • Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res 99: 1355-1366, 2006.
    • (2006) Circ Res , vol.99 , pp. 1355-1366
    • Schefe, J.H.1    Menk, M.2    Reinemund, J.3    Effertz, K.4    Hobbs, R.M.5    Pandolfi, P.P.6    Ruiz, P.7    Unger, T.8    Funke-Kaiser, H.9
  • 35
    • 0035584538 scopus 로고    scopus 로고
    • Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo
    • Wingler K, Wunsch S, Kreutz R, Rothermund L, Paul M, Schmidt HH. Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo. Free Radic Biol Med 31: 1456-1464, 2001.
    • (2001) Free Radic Biol Med , vol.31 , pp. 1456-1464
    • Wingler, K.1    Wunsch, S.2    Kreutz, R.3    Rothermund, L.4    Paul, M.5    Schmidt, H.H.6
  • 37
    • 41149140205 scopus 로고    scopus 로고
    • Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells
    • Xu H, Goettsch C, Xia N, Horke S, Morawietz H, Forstermann U, Li H. Differential roles of PKCalpha and PKCepsilon in controlling the gene expression of Nox4 in human endothelial cells. Free Radic Biol Med 44: 1656-1667, 2008.
    • (2008) Free Radic Biol Med , vol.44 , pp. 1656-1667
    • Xu, H.1    Goettsch, C.2    Xia, N.3    Horke, S.4    Morawietz, H.5    Forstermann, U.6    Li, H.7
  • 39
    • 56049114004 scopus 로고    scopus 로고
    • Receptordependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells
    • Zhang J, Noble NA, Border WA, Owens RT, Huang Y. Receptordependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 295: E810-E819, 2008.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Zhang, J.1    Noble, N.A.2    Border, W.A.3    Owens, R.T.4    Huang, Y.5
  • 40
    • 53149102406 scopus 로고    scopus 로고
    • Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats
    • Zhao W, Zhao T, Chen Y, Ahokas RA, Sun Y. Oxidative stress mediates cardiac fibrosis by enhancing transforming growth factor-beta1 in hypertensive rats. Mol Cell Biochem 317: 43-50, 2008.
    • (2008) Mol Cell Biochem , vol.317 , pp. 43-50
    • Zhao, W.1    Zhao, T.2    Chen, Y.3    Ahokas, R.A.4    Sun, Y.5


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