Receptor-dependent prorenin activation and induction of PAI-1 expression in vascular smooth muscle cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 295, Issue 4, 2008, Pages

  Zhang, Jiandong ^a   Noble, Nancy A ^a   Border, Wayne A ^a   Owens, Rick T ^b   Huang, Yufeng ^a,c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b LIFECELL CORPORATION   (United States)

^c Research Laboratory   (United States)

Author keywords

Diabetes; Fibrosis; Renin angiotensin system

Indexed keywords

ANGIOTENSINOGEN; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; PRORENIN; SARALASIN; SMALL INTERFERING RNA; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; CELL SURFACE RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PRORENIN RECEPTOR; RECOMBINANT PROTEIN; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA MEDIA; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL RAT; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PRODUCTIVITY; RAT; RECEPTOR BINDING; SMOOTH MUSCLE FIBER; SUPERNATANT; VASCULAR SMOOTH MUSCLE; VASCULAR TISSUE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; NEPHRECTOMY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; THORACIC AORTA;

ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; AORTA, THORACIC; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; IMMUNOHISTOCHEMISTRY; MALE; MYOCYTES, SMOOTH MUSCLE; NEPHRECTOMY; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; RENIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SARALASIN;

EID: 56049114004     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90264.2008     Document Type: Article

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