Significant reductions in Gag-Protease-mediated HIV-1 replication capacity during the course of the epidemic in Japan

Journal of Virology

Volumn 87, Issue 3, 2013, Pages 1465-1476

  Nomura, Shigeru ^a   Hosoy, Noriaki ^a   Brumme, Zabrina L ^b,c   Brockman, Mark A ^b,c   Kikuchi, Tadashi ^a   Koga, Michiko ^a   Nakamura, Hitomi ^a   Koibuchi, Tomohiko ^a   Fujii, Takeshi ^a   Carlson, Jonathan M ^d   Heckerman, David ^d   Kawana Tachikawa, Ai ^a   Iwamoto, Aikichi ^a   Miura, Toshiyuki ^a,e,f  

^a UNIVERSITY OF TOKYO   (Japan)

^b SIMON FRASER UNIVERSITY   (Canada)

^c BRITISH COLUMBIA CENTRE FOR EXCELLENCE IN HIV AIDS   (Canada)

^d MICROSOFT RESEARCH   (United States)

^e NAGASAKI UNIVERSITY   (Japan)

^f VIIV HEALTHCARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; GAG PROTEIN;

ARTICLE; CD4 LYMPHOCYTE COUNT; CHIMERA; CONTROLLED STUDY; EPIDEMIC; GENE ACTIVITY; GENE CLUSTER; GENE SEQUENCE; GENETIC DISTANCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; JAPAN; LONG TERMINAL REPEAT; MAJOR CLINICAL STUDY; MOLECULAR EPIDEMIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPORTER GENE; SEQUENCE HOMOLOGY; VIRUS ISOLATION; VIRUS LOAD; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE;

ADOLESCENT; ADULT; AGED; CELL LINE; FEMALE; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HIV INFECTIONS; HIV PROTEASE; HIV-1; HUMANS; JAPAN; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; T-LYMPHOCYTES; VIRUS REPLICATION; YOUNG ADULT;

EID: 84873042035     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02122-12     Document Type: Article

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