-
1
-
-
0029757751
-
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme
-
Back, N. K. T., M. Nijhuis, W. Keulen, C. A. B. Boucher, B. B. O. Essink, A. B. P. van Kuilenburg, A. H. van Gennip, and B. Berkhout. 1996. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J. 15:4040-4049.
-
(1996)
EMBO J.
, vol.15
, pp. 4040-4049
-
-
Back, N.K.T.1
Nijhuis, M.2
Keulen, W.3
Boucher, C.A.B.4
Essink, B.B.O.5
Van Kuilenburg, A.B.P.6
Van Gennip, A.H.7
Berkhout, B.8
-
2
-
-
0031000756
-
Human immunodeficiency virus drug therapy and virus load
-
Bonhoeffer, S., J. M. Coffin, and M. A. Nowak. 1997. Human immunodeficiency virus drug therapy and virus load. J. Virol. 71:3275-3278.
-
(1997)
J. Virol.
, vol.71
, pp. 3275-3278
-
-
Bonhoeffer, S.1
Coffin, J.M.2
Nowak, M.A.3
-
3
-
-
0027373308
-
High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase
-
Boucher, C. A. B., N. Cammack, P. Schipper, R. Schuurman, P. Rouse, M. A. Wainberg, and J. M. Cameron. 1993. High-level resistance to (-) enantiomeric 2′-deoxy-3′-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 37:2231-2234.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 2231-2234
-
-
Boucher, C.A.B.1
Cammack, N.2
Schipper, P.3
Schuurman, R.4
Rouse, P.5
Wainberg, M.A.6
Cameron, J.M.7
-
4
-
-
0030913366
-
Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
-
Chun, T. W., L. Carruth, D. Finzi, X. F. Shen, J. A. Di Giuseppe, H. Taylor, M. Hermankova, K. Chadwick, J. Margolick, T. C. Quinn, Y. H. Kuo, R. Brookmeyer, M. A. Zeiger, P. Barditch Crovo, and R. F. Siliciano. 1997. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387:183-188.
-
(1997)
Nature
, vol.387
, pp. 183-188
-
-
Chun, T.W.1
Carruth, L.2
Finzi, D.3
Shen, X.F.4
Di Giuseppe, J.A.5
Taylor, H.6
Hermankova, M.7
Chadwick, K.8
Margolick, J.9
Quinn, T.C.10
Kuo, Y.H.11
Brookmeyer, R.12
Zeiger, M.A.13
Barditch Crovo, P.14
Siliciano, R.F.15
-
5
-
-
0028952146
-
HIV population dynamics in vivo - Implications for genetic variation, pathogenesis, and therapy
-
Coffin, J. M. 1995. HIV population dynamics in vivo - implications for genetic variation, pathogenesis, and therapy. Science 267:483-489.
-
(1995)
Science
, vol.267
, pp. 483-489
-
-
Coffin, J.M.1
-
7
-
-
0031950370
-
Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (norvir) monotherapy
-
Eastman, P. S., J. Mittler, R. Kelso, C. Gee, E. Boyer, J. Kolberg, M. Urdea, J. M. Leonard, D. W. Norbeck, H. Mo, and M. Markowitz. 1998. Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (norvir) monotherapy. J. Virol. 72:5154-5164.
-
(1998)
J. Virol.
, vol.72
, pp. 5154-5164
-
-
Eastman, P.S.1
Mittler, J.2
Kelso, R.3
Gee, C.4
Boyer, E.5
Kolberg, J.6
Urdea, M.7
Leonard, J.M.8
Norbeck, D.W.9
Mo, H.10
Markowitz, M.11
-
8
-
-
2542583245
-
The fate of competing beneficial mutations in an asexual population
-
Gerrish, P. J., and R. E. Lenski. 1998. The fate of competing beneficial mutations in an asexual population. Genetica 103:127-144.
-
(1998)
Genetica
, vol.103
, pp. 127-144
-
-
Gerrish, P.J.1
Lenski, R.E.2
-
9
-
-
84955349191
-
A mathematical theory of natural and artilicial selection
-
Haldane, J. B. S. 1927. A mathematical theory of natural and artilicial selection. Proc. Camb. Phil. Soc. 28:838-844.
-
(1927)
Proc. Camb. Phil. Soc.
, vol.28
, pp. 838-844
-
-
Haldane, J.B.S.1
-
10
-
-
0029798237
-
Nevirapine-resistant human immunodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients
-
Havlir, D. V., S. Eastman, A. Gamst, and D. D. Richman. 1996. Nevirapine-resistant human immunodeficiency virus: kinetics of replication and estimated prevalence in untreated patients. J. Virol. 70:7894-7899.
-
(1996)
J. Virol.
, vol.70
, pp. 7894-7899
-
-
Havlir, D.V.1
Eastman, S.2
Gamst, A.3
Richman, D.D.4
-
11
-
-
0013979181
-
The effect of linkage on limits to artificial selection
-
Hill, W. G., and A. Robertson. 1966. The effect of linkage on limits to artificial selection. Genet. Res. 8:269-294.
-
(1966)
Genet. Res.
, vol.8
, pp. 269-294
-
-
Hill, W.G.1
Robertson, A.2
-
12
-
-
0028874048
-
Rapid turnover of plasma virions and CD4+ lymphocytes in HIV-1 cells
-
Ho, D. D., A. U. Neumann, A. S. Perelson, W. Chen, J. M. Leonard, and M. Markowitz. 1995. Rapid turnover of plasma virions and CD4+ lymphocytes in HIV-1 cells. Nature 373:123-126.
-
(1995)
Nature
, vol.373
, pp. 123-126
-
-
Ho, D.D.1
Neumann, A.U.2
Perelson, A.S.3
Chen, W.4
Leonard, J.M.5
Markowitz, M.6
-
13
-
-
0028289584
-
Fidelity of HIV-1 reverse transcriptase copying a hypervariable region of the HIV-1 env gene
-
Ji, J., and L. A. Loeb. 1994. Fidelity of HIV-1 reverse transcriptase copying a hypervariable region of the HIV-1 env gene. Virology 199:323-330.
-
(1994)
Virology
, vol.199
, pp. 323-330
-
-
Ji, J.1
Loeb, L.A.2
-
14
-
-
0026753190
-
A microtitre format point mutation assay - Application to the detection of drug resistance in human immunodeficiency virus type 1 infected patients treated with zidovudine
-
Kaye, S., C. Loveday, and R. S. Tedder. 1992. A microtitre format point mutation assay - application to the detection of drug resistance in human immunodeficiency virus type 1 infected patients treated with zidovudine. J. Med. Virol. 37:241-246.
-
(1992)
J. Med. Virol.
, vol.37
, pp. 241-246
-
-
Kaye, S.1
Loveday, C.2
Tedder, R.S.3
-
15
-
-
0031925680
-
A novel polymorphism at codon 333 of human immunodeficiency virus type 1 reverse transcriptase can facilitate dual resistance to zidovudine and L-2′,3′-dideoxy-3′-thiacytidine
-
Kemp, S. D., C. Shi, S. Bloor, P. R. Harrigan, J. W. Mellors, and B. A. Larder. 1998. A novel polymorphism at codon 333 of human immunodeficiency virus type 1 reverse transcriptase can facilitate dual resistance to zidovudine and L-2′,3′-dideoxy-3′-thiacytidine. J. Virol. 72:5093-5098.
-
(1998)
J. Virol.
, vol.72
, pp. 5093-5098
-
-
Kemp, S.D.1
Shi, C.2
Bloor, S.3
Harrigan, P.R.4
Mellors, J.W.5
Larder, B.A.6
-
16
-
-
0002024698
-
On some modes of population growth leading to R. A. Fisher's logarithmic series distribution
-
Kendall, D. G. 1948. On some modes of population growth leading to R. A. Fisher's logarithmic series distribution. Biometrika 35:6-15.
-
(1948)
Biometrika
, vol.35
, pp. 6-15
-
-
Kendall, D.G.1
-
17
-
-
0030896362
-
Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase
-
Keulen, W., N. K. T. Back, A. van Wijk, C. A. B. Boucher, and B. Berkhout. 1997. Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase. J. Virol. 71:3346-3350.
-
(1997)
J. Virol.
, vol.71
, pp. 3346-3350
-
-
Keulen, W.1
Back, N.K.T.2
Van Wijk, A.3
Boucher, C.A.B.4
Berkhout, B.5
-
19
-
-
0004732896
-
Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population
-
Leigh Brown, A. J. 1997. Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population. Proc. Natl. Acad. Sci. USA 94:1862-1865.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1862-1865
-
-
Leigh Brown, A.J.1
-
20
-
-
0031054436
-
HIV-1: Gambling on the evolution of drug resistance?
-
Leigh Brown, A. J., and D. D. Richman. 1997. HIV-1: gambling on the evolution of drug resistance? Nat. Med. 3:268-271.
-
(1997)
Nat. Med.
, vol.3
, pp. 268-271
-
-
Leigh Brown, A.J.1
Richman, D.D.2
-
21
-
-
77649173768
-
Longitudinal data analysis using generalized linear models
-
Liang, K. Y., and S. L. Zeger. 1986. Longitudinal data analysis using generalized linear models. Biometrika 73:13-22.
-
(1986)
Biometrika
, vol.73
, pp. 13-22
-
-
Liang, K.Y.1
Zeger, S.L.2
-
22
-
-
0030818643
-
Lamivudine-resistant human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-resistant to zidovudine in vivo
-
Nijhuis, M., K. Schuurman, D. de Jong, R. van Leeuwen, J. Lange, S. Danner, W. Keulen, T. de Groot, and C. A. B. Boucher. 1997. Lamivudine-resistant human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-resistant to zidovudine in vivo. J. Infect. Dis. 176:398-405.
-
(1997)
J. Infect. Dis.
, vol.176
, pp. 398-405
-
-
Nijhuis, M.1
Schuurman, K.2
De Jong, D.3
Van Leeuwen, R.4
Lange, J.5
Danner, S.6
Keulen, W.7
De Groot, T.8
Boucher, C.A.B.9
-
23
-
-
0032564366
-
Stochastic processes strongly influence HIV-1 evolution during suboptimal protease inhibitor therapy
-
Nijhuis, M., C. A. B. Boucher, P. Schipper, T. Leitner, R. Schuurman, and J. Albert. 1998. Stochastic processes strongly influence HIV-1 evolution during suboptimal protease inhibitor therapy. Proc. Natl. Acad. Sci. USA 95:14441-14446.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14441-14446
-
-
Nijhuis, M.1
Boucher, C.A.B.2
Schipper, P.3
Leitner, T.4
Schuurman, R.5
Albert, J.6
-
24
-
-
0029967721
-
HIV-1 dynamics in vivo: Virion clearance rate, infected cell lifespan, and viral generation time
-
Perelson, A. S., A. U. Neumann, M. Markowitz, J. M. Leonard, and D. D. Ho. 1996. HIV-1 dynamics in vivo: virion clearance rate, infected cell lifespan, and viral generation time. Science 271:1582-1586.
-
(1996)
Science
, vol.271
, pp. 1582-1586
-
-
Perelson, A.S.1
Neumann, A.U.2
Markowitz, M.3
Leonard, J.M.4
Ho, D.D.5
-
25
-
-
0032824180
-
Linkage disequilibrium test implies a large effective population number for HIV in vivo
-
Rouzine, I. M., and J. M. Coffin. 1999. Linkage disequilibrium test implies a large effective population number for HIV in vivo. Proc. Natl. Acad. Sci. USA 96:10758-10763.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10758-10763
-
-
Rouzine, I.M.1
Coffin, J.M.2
-
26
-
-
0029024089
-
Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant populations in persons treated with lamivudine (3TC)
-
Schuurman, R., M. Nijhuis, R. van Leeuwen, P. Schipper, D. de Jong, P. Collis, S. A. Danner, J. Mulder, C. Loveday, C. Christopherson, S. Kwok, J. Sninsky, and C. A. B. Boucher. 1995. Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant populations in persons treated with lamivudine (3TC). J. Infect. Dis. 171:1411-1419.
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1411-1419
-
-
Schuurman, R.1
Nijhuis, M.2
Van Leeuwen, R.3
Schipper, P.4
De Jong, D.5
Collis, P.6
Danner, S.A.7
Mulder, J.8
Loveday, C.9
Christopherson, C.10
Kwok, S.11
Sninsky, J.12
Boucher, C.A.B.13
-
27
-
-
0025650533
-
A primer-guided nucleotide incorporation assay in the gcnotyping of apoliprotein-E
-
Syvanen, A. C., K. Aalto-Setala, L. Harju, K. Kontula, and H. Soderlund. 1990. A primer-guided nucleotide incorporation assay in the gcnotyping of apoliprotein-E. Genomics 8:684-692.
-
(1990)
Genomics
, vol.8
, pp. 684-692
-
-
Syvanen, A.C.1
Aalto-Setala, K.2
Harju, L.3
Kontula, K.4
Soderlund, H.5
-
28
-
-
0028948198
-
Evaluation of safety and efficacy of 3TC (lamivudine) in patients with asymptomatic or mildly symptomatic human immunodeficiency virus infection - A phase I/II study
-
Van Leeuwen, R., C. Kallama, V. Kitchen, C. A. B. Boucher, R. Tubiana, M. McBride, D. Ingrand, J. Weber, A. Hill, H. McDade, and S. A. Danner. 1995. Evaluation of safety and efficacy of 3TC (lamivudine) in patients with asymptomatic or mildly symptomatic human immunodeficiency virus infection - a phase I/II study. J. Infect. Dis. 171:1166-1171.
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1166-1171
-
-
Van Leeuwen, R.1
Kallama, C.2
Kitchen, V.3
Boucher, C.A.B.4
Tubiana, R.5
McBride, M.6
Ingrand, D.7
Weber, J.8
Hill, A.9
McDade, H.10
Danner, S.A.11
-
29
-
-
0030512725
-
Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC resistant HIV-1 reverse transcriptase
-
Wainberg, M. A., M. Hsu, Z. X. Gu, G. Borkow, and M. A. Parniak. 1996. Effectiveness of 3TC in HIV clinical trials may be due in part to the M184V substitution in 3TC resistant HIV-1 reverse transcriptase. AIDS 10(Suppl. 5):S3-S10.
-
(1996)
AIDS
, vol.10
, Issue.SUPPL. 5
-
-
Wainberg, M.A.1
Hsu, M.2
Gu, Z.X.3
Borkow, G.4
Parniak, M.A.5
-
30
-
-
0028811974
-
Viral dynamics in human immunodeficiency type 1 infection
-
Wei, X., S. K. Ghosh, M. E. Taylor, V. A. Johnson, E. A. Emini, P. Deutsch, J. D. Lifson, S. Bonhoeffer, M. A. Nowak, B. H. Hahn, M. S. Saag, and G. M. Shaw. 1995. Viral dynamics in human immunodeficiency type 1 infection. Nature 373:117-122.
-
(1995)
Nature
, vol.373
, pp. 117-122
-
-
Wei, X.1
Ghosh, S.K.2
Taylor, M.E.3
Johnson, V.A.4
Emini, E.A.5
Deutsch, P.6
Lifson, J.D.7
Bonhoeffer, S.8
Nowak, M.A.9
Hahn, B.H.10
Saag, M.S.11
Shaw, G.M.12
|