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Volumn 4, Issue 8, 2009, Pages

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins

(21)  Brumme, Zabrina L a,b   John, Mina c   Carlson, Jonathan M d   Brumme, Chanson J a   Chan, Dennison e   Brockman, Mark A a,b   Swenson, Luke C e   Tao, Iris e   Szeto, Sharon e   Rosato, Pamela a   Sela, Jennifer a   Kadie, Carl M d   Frahm, Nicole a,m   Brander, Christian a,f,g   Haas, David W h   Riddler, Sharon A i   Haubrich, Richard j   Walker, Bruce D a,k   Harrigan, P Richard e,l   Heckerman, David d   more..


Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; HLA ANTIGEN; NEF PROTEIN; POL PROTEIN;

EID: 68949209789     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006687     Document Type: Article
Times cited : (146)

References (60)
  • 1
    • 0028337166 scopus 로고
    • Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome
    • Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, et al. (1994) Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 68: 4650-4655.
    • (1994) J Virol , vol.68 , pp. 4650-4655
    • Koup, R.A.1    Safrit, J.T.2    Cao, Y.3    Andrews, C.A.4    McLeod, G.5
  • 2
    • 0028041344 scopus 로고
    • Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
    • Borrow P, Lewicki H, Hahn BH, Shaw GM, Oldstone MB (1994) Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 68: 6103-6110.
    • (1994) J Virol , vol.68 , pp. 6103-6110
    • Borrow, P.1    Lewicki, H.2    Hahn, B.H.3    Shaw, G.M.4    Oldstone, M.B.5
  • 3
    • 0031985775 scopus 로고    scopus 로고
    • Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques
    • Matano T, Shibata R, Siemon C, Connors M, Lane HC, et al. (1998) Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J Virol 72: 164-169.
    • (1998) J Virol , vol.72 , pp. 164-169
    • Matano, T.1    Shibata, R.2    Siemon, C.3    Connors, M.4    Lane, H.C.5
  • 4
    • 0033524838 scopus 로고    scopus 로고
    • Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes
    • Schmitz JE, Kuroda MJ, Santra S, Sasseville VG, Simon MA, et al. (1999) Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. Science 283: 857-860.
    • (1999) Science , vol.283 , pp. 857-860
    • Schmitz, J.E.1    Kuroda, M.J.2    Santra, S.3    Sasseville, V.G.4    Simon, M.A.5
  • 5
    • 0038581912 scopus 로고    scopus 로고
    • The influence of HLA genotype on AIDS
    • Carrington M, O'Brien SJ (2003) The influence of HLA genotype on AIDS. Annu Rev Med 54: 535-551.
    • (2003) Annu Rev Med , vol.54 , pp. 535-551
    • Carrington, M.1    O'Brien, S.J.2
  • 6
    • 48749103238 scopus 로고    scopus 로고
    • Impact of MHC class I diversity on immune control of immunodeficiency virus replication
    • Goulder PJ, Watkins DI (2008) Impact of MHC class I diversity on immune control of immunodeficiency virus replication. Nat Rev Immunol 8: 619-630.
    • (2008) Nat Rev Immunol , vol.8 , pp. 619-630
    • Goulder, P.J.1    Watkins, D.I.2
  • 8
    • 50449090525 scopus 로고    scopus 로고
    • An HIV vaccine-challenges and prospects
    • Johnston MI, Fauci AS (2008) An HIV vaccine-challenges and prospects. N Engl J Med 359: 888-890.
    • (2008) N Engl J Med , vol.359 , pp. 888-890
    • Johnston, M.I.1    Fauci, A.S.2
  • 9
    • 44949100369 scopus 로고    scopus 로고
    • Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans
    • Watkins DI, Burton DR, Kallas EG, Moore JP, Koff WC (2008) Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans. Nat Med 14: 617-621.
    • (2008) Nat Med , vol.14 , pp. 617-621
    • Watkins, D.I.1    Burton, D.R.2    Kallas, E.G.3    Moore, J.P.4    Koff, W.C.5
  • 10
    • 44049108744 scopus 로고    scopus 로고
    • Toward an AIDS vaccine
    • Walker BD, Burton DR (2008) Toward an AIDS vaccine. Science 320: 760-764.
    • (2008) Science , vol.320 , pp. 760-764
    • Walker, B.D.1    Burton, D.R.2
  • 11
    • 34548698462 scopus 로고    scopus 로고
    • Correlates of immune protection and the development of a human immunodeficiency virus vaccine
    • Letvin NL (2007) Correlates of immune protection and the development of a human immunodeficiency virus vaccine. Immunity 27: 366-369.
    • (2007) Immunity , vol.27 , pp. 366-369
    • Letvin, N.L.1
  • 12
    • 0034618869 scopus 로고    scopus 로고
    • The HLA system. First of two parts
    • Klein J, Sato A (2000) The HLA system. First of two parts. N Engl J Med 343: 702-709.
    • (2000) N Engl J Med , vol.343 , pp. 702-709
    • Klein, J.1    Sato, A.2
  • 14
    • 0037165969 scopus 로고    scopus 로고
    • Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level
    • Moore CB, John M, James IR, Christiansen FT, Witt CS, et al. (2002) Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level. Science 296: 1439-1443.
    • (2002) Science , vol.296 , pp. 1439-1443
    • Moore, C.B.1    John, M.2    James, I.R.3    Christiansen, F.T.4    Witt, C.S.5
  • 15
    • 34547643061 scopus 로고    scopus 로고
    • Brumme ZL, Brumme CJ, Heckerman D, Korber BT, Daniels M, et al. (2007) Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1. PLoS Pathog 3: e94.
    • Brumme ZL, Brumme CJ, Heckerman D, Korber BT, Daniels M, et al. (2007) Evidence of Differential HLA Class I-Mediated Viral Evolution in Functional and Accessory/Regulatory Genes of HIV-1. PLoS Pathog 3: e94.
  • 16
    • 31344452079 scopus 로고    scopus 로고
    • Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope
    • Iversen AK, Stewart-Jones G, Learn GH, Christie N, Sylvester-Hviid C, et al. (2006) Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope. Nat Immunol 7: 179-189.
    • (2006) Nat Immunol , vol.7 , pp. 179-189
    • Iversen, A.K.1    Stewart-Jones, G.2    Learn, G.H.3    Christie, N.4    Sylvester-Hviid, C.5
  • 17
    • 16944365445 scopus 로고    scopus 로고
    • Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus
    • Borrow P, Lewicki H, Wei X, Horwitz MS, Peffer N, et al. (1997) Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus. Nat Med 3: 205-211.
    • (1997) Nat Med , vol.3 , pp. 205-211
    • Borrow, P.1    Lewicki, H.2    Wei, X.3    Horwitz, M.S.4    Peffer, N.5
  • 18
    • 0028145416 scopus 로고
    • Virus escape from CTL recognition
    • Koup RA (1994) Virus escape from CTL recognition. J Exp Med 180: 779-782.
    • (1994) J Exp Med , vol.180 , pp. 779-782
    • Koup, R.A.1
  • 20
    • 0025827529 scopus 로고
    • Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition
    • Phillips RE, Rowland-Jones S, Nixon DF, Gotch FM, Edwards JP, et al. (1991) Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature 354: 453-459.
    • (1991) Nature , vol.354 , pp. 453-459
    • Phillips, R.E.1    Rowland-Jones, S.2    Nixon, D.F.3    Gotch, F.M.4    Edwards, J.P.5
  • 21
    • 2942672080 scopus 로고    scopus 로고
    • Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection
    • Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, et al. (2004) Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection. J Virol 78: 7069-7078.
    • (2004) J Virol , vol.78 , pp. 7069-7078
    • Allen, T.M.1    Altfeld, M.2    Yu, X.G.3    O'Sullivan, K.M.4    Lichterfeld, M.5
  • 22
    • 11144357869 scopus 로고    scopus 로고
    • Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection
    • Draenert R, Le Gall S, Pfafferott KJ, Leslie AJ, Chetty P, et al. (2004) Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection. J Exp Med 199: 905-915.
    • (2004) J Exp Med , vol.199 , pp. 905-915
    • Draenert, R.1    Le Gall, S.2    Pfafferott, K.J.3    Leslie, A.J.4    Chetty, P.5
  • 23
    • 20444426834 scopus 로고    scopus 로고
    • A new variant cytotoxic T lymphocyte escape mutation in HLA-B27-positive individuals infected with HIV type 1
    • Ammaranond P, Zaunders J, Satchell C, van Bockel D, Cooper DA, et al. (2005) A new variant cytotoxic T lymphocyte escape mutation in HLA-B27-positive individuals infected with HIV type 1. AIDS Res Hum Retroviruses 21: 395-397.
    • (2005) AIDS Res Hum Retroviruses , vol.21 , pp. 395-397
    • Ammaranond, P.1    Zaunders, J.2    Satchell, C.3    van Bockel, D.4    Cooper, D.A.5
  • 24
    • 0035808775 scopus 로고    scopus 로고
    • Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses
    • Kelleher AD, Long C, Holmes EC, Allen RL, Wilson J, et al. (2001) Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses. J Exp Med 193: 375-386.
    • (2001) J Exp Med , vol.193 , pp. 375-386
    • Kelleher, A.D.1    Long, C.2    Holmes, E.C.3    Allen, R.L.4    Wilson, J.5
  • 25
    • 3543078012 scopus 로고    scopus 로고
    • HIV and SIV CTL escape: Implications for vaccine design
    • Goulder PJ, Watkins DI (2004) HIV and SIV CTL escape: implications for vaccine design. Nat Rev Immunol 4: 630-640.
    • (2004) Nat Rev Immunol , vol.4 , pp. 630-640
    • Goulder, P.J.1    Watkins, D.I.2
  • 26
    • 10344231446 scopus 로고    scopus 로고
    • T cell receptor recognition motifs govern immune escape patterns in acute SIV infection
    • Price DA, West SM, Betts MR, Ruff LE, Brenchley JM, et al. (2004) T cell receptor recognition motifs govern immune escape patterns in acute SIV infection. Immunity 21: 793-803.
    • (2004) Immunity , vol.21 , pp. 793-803
    • Price, D.A.1    West, S.M.2    Betts, M.R.3    Ruff, L.E.4    Brenchley, J.M.5
  • 27
    • 57149090493 scopus 로고    scopus 로고
    • Carlson JM, Brumme ZL, Rousseau CM, Brumme CJ, Matthews P, et al. (2008) Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag. PLoS Comput Biol 4: e1000225.
    • Carlson JM, Brumme ZL, Rousseau CM, Brumme CJ, Matthews P, et al. (2008) Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag. PLoS Comput Biol 4: e1000225.
  • 28
    • 50149117938 scopus 로고    scopus 로고
    • Central role of reverting mutations in HLA associations with human immunodeficiency virus set point
    • Matthews PC, Prendergast A, Leslie A, Crawford H, Payne R, et al. (2008) Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. J Virol 82: 8548-8559.
    • (2008) J Virol , vol.82 , pp. 8548-8559
    • Matthews, P.C.1    Prendergast, A.2    Leslie, A.3    Crawford, H.4    Payne, R.5
  • 29
    • 45749104088 scopus 로고    scopus 로고
    • HLA Class-I Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load
    • Rousseau CM, Daniels MG, Carlson JM, Kadie C, Crawford H, et al. (2008) HLA Class-I Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load. J Virol 82: 6434-6446.
    • (2008) J Virol , vol.82 , pp. 6434-6446
    • Rousseau, C.M.1    Daniels, M.G.2    Carlson, J.M.3    Kadie, C.4    Crawford, H.5
  • 30
    • 27144513224 scopus 로고    scopus 로고
    • Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution
    • Allen TM, Altfeld M, Geer SC, Kalife ET, Moore C, et al. (2005) Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution. J Virol 79: 13239-13249.
    • (2005) J Virol , vol.79 , pp. 13239-13249
    • Allen, T.M.1    Altfeld, M.2    Geer, S.C.3    Kalife, E.T.4    Moore, C.5
  • 31
    • 1842741699 scopus 로고    scopus 로고
    • HIV evolution: CTL escape mutation and reversion after transmission
    • Leslie AJ, Pfafferott KJ, Chetty P, Draenert R, Addo MM, et al. (2004) HIV evolution: CTL escape mutation and reversion after transmission. Nat Med 10: 282-289.
    • (2004) Nat Med , vol.10 , pp. 282-289
    • Leslie, A.J.1    Pfafferott, K.J.2    Chetty, P.3    Draenert, R.4    Addo, M.M.5
  • 32
    • 50949117244 scopus 로고    scopus 로고
    • Marked epitope and allele-specific differences in rates of mutation in HIV-1 Gag, Pol and Nef CTL epitopes in acute/early HIV-1 infection
    • Brumme ZL, Brumme CJ, Carlson J, Streeck H, John M, et al. (2008) Marked epitope and allele-specific differences in rates of mutation in HIV-1 Gag, Pol and Nef CTL epitopes in acute/early HIV-1 infection. J Virol 82: 9216-9227.
    • (2008) J Virol , vol.82 , pp. 9216-9227
    • Brumme, Z.L.1    Brumme, C.J.2    Carlson, J.3    Streeck, H.4    John, M.5
  • 33
    • 59749085611 scopus 로고    scopus 로고
    • HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection
    • Duda A, Lee-Turner L, Fox J, Robinson N, Dustan S, et al. (2009) HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection. J Virol 83: 1228-1239.
    • (2009) J Virol , vol.83 , pp. 1228-1239
    • Duda, A.1    Lee-Turner, L.2    Fox, J.3    Robinson, N.4    Dustan, S.5
  • 34
    • 28644451011 scopus 로고    scopus 로고
    • AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis
    • Gao X, Bashirova A, Iversen AK, Phair J, Goedert JJ, et al. (2005) AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis. Nat Med 11: 1290-1292.
    • (2005) Nat Med , vol.11 , pp. 1290-1292
    • Gao, X.1    Bashirova, A.2    Iversen, A.K.3    Phair, J.4    Goedert, J.J.5
  • 35
    • 36048995423 scopus 로고    scopus 로고
    • Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A
    • Brockman MA, Schneidewind A, Lahaie M, Schmidt A, Miura T, et al. (2007) Escape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A. J Virol 81: 12608-12618.
    • (2007) J Virol , vol.81 , pp. 12608-12618
    • Brockman, M.A.1    Schneidewind, A.2    Lahaie, M.3    Schmidt, A.4    Miura, T.5
  • 36
    • 36048949732 scopus 로고    scopus 로고
    • Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication
    • Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, et al. (2007) Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication. J Virol 81: 12382-12393.
    • (2007) J Virol , vol.81 , pp. 12382-12393
    • Schneidewind, A.1    Brockman, M.A.2    Yang, R.3    Adam, R.I.4    Li, B.5
  • 37
    • 33947399689 scopus 로고    scopus 로고
    • Founder effects in the assessment of HIV polymorphisms and HLA allele associations
    • Bhattacharya T, Daniels M, Heckerman D, Foley B, Frahm N, et al. (2007) Founder effects in the assessment of HIV polymorphisms and HLA allele associations. Science 315: 1583-1586.
    • (2007) Science , vol.315 , pp. 1583-1586
    • Bhattacharya, T.1    Daniels, M.2    Heckerman, D.3    Foley, B.4    Frahm, N.5
  • 38
    • 49849087657 scopus 로고    scopus 로고
    • Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection
    • Brumme ZL, Tao I, Szeto S, Brumme CJ, Carlson JM, et al. (2008) Human leukocyte antigen-specific polymorphisms in HIV-1 Gag and their association with viral load in chronic untreated infection. AIDS 22: 1277-1286.
    • (2008) AIDS , vol.22 , pp. 1277-1286
    • Brumme, Z.L.1    Tao, I.2    Szeto, S.3    Brumme, C.J.4    Carlson, J.M.5
  • 40
    • 46349112103 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel
    • Hirsch MS, Gunthard HF, Schapiro JM, Brun-Vezinet F, Clotet B, et al. (2008) Antiretroviral drug resistance testing in adult HIV-1 infection: 2008 recommendations of an International AIDS Society-USA panel. Clin Infect Dis 47: 266-285.
    • (2008) Clin Infect Dis , vol.47 , pp. 266-285
    • Hirsch, M.S.1    Gunthard, H.F.2    Schapiro, J.M.3    Brun-Vezinet, F.4    Clotet, B.5
  • 42
    • 0142155149 scopus 로고    scopus 로고
    • A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128
    • Haas DW, Wilkinson GR, Kuritzkes DR, Richman DD, Nicotera J, et al. (2003) A multi-investigator/institutional DNA bank for AIDS-related human genetic studies: AACTG Protocol A5128. HIV Clin Trials 4: 287-300.
    • (2003) HIV Clin Trials , vol.4 , pp. 287-300
    • Haas, D.W.1    Wilkinson, G.R.2    Kuritzkes, D.R.3    Richman, D.D.4    Nicotera, J.5
  • 43
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R (2003) Statistical significance for genomewide studies. Proc Natl Acad Sci U S A 100: 9440-9445.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 44
    • 10744226946 scopus 로고    scopus 로고
    • Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities
    • Frahm N, Korber BT, Adams CM, Szinger JJ, Draenert R, et al. (2004) Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J Virol 78: 2187-2200.
    • (2004) J Virol , vol.78 , pp. 2187-2200
    • Frahm, N.1    Korber, B.T.2    Adams, C.M.3    Szinger, J.J.4    Draenert, R.5
  • 46
    • 0242661850 scopus 로고    scopus 로고
    • Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individual
    • Geels MJ, Cornelissen M, Schuitemaker H, Anderson K, Kwa D, et al. (2003) Identification of sequential viral escape mutants associated with altered T-cell responses in a human immunodeficiency virus type 1-infected individual. J Virol 77: 12430-12440.
    • (2003) J Virol , vol.77 , pp. 12430-12440
    • Geels, M.J.1    Cornelissen, M.2    Schuitemaker, H.3    Anderson, K.4    Kwa, D.5
  • 47
    • 33750869972 scopus 로고    scopus 로고
    • HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1
    • Altfeld M, Kalife ET, Qi Y, Streeck H, Lichterfeld M, et al. (2006) HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. PLoS Med 3: e403.
    • (2006) PLoS Med , vol.3
    • Altfeld, M.1    Kalife, E.T.2    Qi, Y.3    Streeck, H.4    Lichterfeld, M.5
  • 48
    • 59649108841 scopus 로고    scopus 로고
    • Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1
    • Wang YE, Li B, Carlson JM, Streeck H, Gladden AD, et al. (2009) Protective HLA class I alleles that restrict acute-phase CD8+ T-cell responses are associated with viral escape mutations located in highly conserved regions of human immunodeficiency virus type 1. J Virol 83: 1845-1855.
    • (2009) J Virol , vol.83 , pp. 1845-1855
    • Wang, Y.E.1    Li, B.2    Carlson, J.M.3    Streeck, H.4    Gladden, A.D.5
  • 49
    • 68949200706 scopus 로고    scopus 로고
    • Frahm N, L C, Brander C (2006) Identification of HIV-derived, HLA class I restricted CTL epitopes: Insights into TCR repertoire, CTL escape and viral fitness. In: Korber BB, C, Haynes BF, Koup R, Moore JP, Walker BD, Watkins DI, eds (2006) HIV Molecular Immunology 2006/2007: Los Alamos National Laboratory, Theoretical Biology and Biophysics. pp 3-28.
    • Frahm N, L C, Brander C (2006) Identification of HIV-derived, HLA class I restricted CTL epitopes: Insights into TCR repertoire, CTL escape and viral fitness. In: Korber BB, C, Haynes BF, Koup R, Moore JP, Walker BD, Watkins DI, eds (2006) HIV Molecular Immunology 2006/2007: Los Alamos National Laboratory, Theoretical Biology and Biophysics. pp 3-28.
  • 50
    • 0006582115 scopus 로고    scopus 로고
    • Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection
    • Kaslow RA, Carrington M, Apple R, Park L, Munoz A, et al. (1996) Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection. Nat Med 2: 405-411.
    • (1996) Nat Med , vol.2 , pp. 405-411
    • Kaslow, R.A.1    Carrington, M.2    Apple, R.3    Park, L.4    Munoz, A.5
  • 51
    • 0036171258 scopus 로고    scopus 로고
    • Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma
    • Edwards BH, Bansal A, Sabbaj S, Bakari J, Mulligan MJ, et al. (2002) Magnitude of functional CD8+ T-cell responses to the gag protein of human immunodeficiency virus type 1 correlates inversely with viral load in plasma. J Virol 76: 2298-2305.
    • (2002) J Virol , vol.76 , pp. 2298-2305
    • Edwards, B.H.1    Bansal, A.2    Sabbaj, S.3    Bakari, J.4    Mulligan, M.J.5
  • 52
    • 33644755541 scopus 로고    scopus 로고
    • Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control
    • Zuniga R, Lucchetti A, Galvan P, Sanchez S, Sanchez C, et al. (2006) Relative dominance of Gag p24-specific cytotoxic T lymphocytes is associated with human immunodeficiency virus control. J Virol 80: 3122-3125.
    • (2006) J Virol , vol.80 , pp. 3122-3125
    • Zuniga, R.1    Lucchetti, A.2    Galvan, P.3    Sanchez, S.4    Sanchez, C.5
  • 53
    • 33846101731 scopus 로고    scopus 로고
    • CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
    • Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, et al. (2007) CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. Nat Med 13: 46-53.
    • (2007) Nat Med , vol.13 , pp. 46-53
    • Kiepiela, P.1    Ngumbela, K.2    Thobakgale, C.3    Ramduth, D.4    Honeyborne, I.5
  • 54
    • 33645240933 scopus 로고    scopus 로고
    • Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1
    • Martinez-Picado J, Prado JG, Fry EE, Pfafferott K, Leslie A, et al. (2006) Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. J Virol 80: 3617-3623.
    • (2006) J Virol , vol.80 , pp. 3617-3623
    • Martinez-Picado, J.1    Prado, J.G.2    Fry, E.E.3    Pfafferott, K.4    Leslie, A.5
  • 56
    • 44649153892 scopus 로고    scopus 로고
    • SYFPEITHI: Database for searching and T-cell epitope prediction
    • Schuler MM, Nastke MD, Stevanovikc S (2007) SYFPEITHI: database for searching and T-cell epitope prediction. Methods Mol Biol 409: 75-93.
    • (2007) Methods Mol Biol , vol.409 , pp. 75-93
    • Schuler, M.M.1    Nastke, M.D.2    Stevanovikc, S.3
  • 57
    • 23844528191 scopus 로고    scopus 로고
    • An integrative approach to CTL epitope prediction: A combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions
    • Larsen MV, Lundegaard C, Lamberth K, Buus S, Brunak S, et al. (2005) An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions. Eur J Immunol 35: 2295-2303.
    • (2005) Eur J Immunol , vol.35 , pp. 2295-2303
    • Larsen, M.V.1    Lundegaard, C.2    Lamberth, K.3    Buus, S.4    Brunak, S.5
  • 58
    • 58049217445 scopus 로고    scopus 로고
    • Pan-specific MHC class I predictors: A benchmark of HLA class I pan-specific prediction methods
    • Zhang H, Lundegaard C, Nielsen M (2009) Pan-specific MHC class I predictors: a benchmark of HLA class I pan-specific prediction methods. Bioinformatics 25: 83-89.
    • (2009) Bioinformatics , vol.25 , pp. 83-89
    • Zhang, H.1    Lundegaard, C.2    Nielsen, M.3
  • 59
    • 38049169092 scopus 로고    scopus 로고
    • Largescale validation of methods for cytotoxic T-lymphocyte epitope prediction
    • Larsen MV, Lundegaard C, Lamberth K, Buus S, Lund O, et al. (2007) Largescale validation of methods for cytotoxic T-lymphocyte epitope prediction. BMC Bioinformatics 8: 424.
    • (2007) BMC Bioinformatics , vol.8 , pp. 424
    • Larsen, M.V.1    Lundegaard, C.2    Lamberth, K.3    Buus, S.4    Lund, O.5
  • 60
    • 43949094512 scopus 로고    scopus 로고
    • Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid
    • Schneidewind A, Brockman MA, Sidney J, Wang YE, Chen H, et al. (2008) Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid. J Virol 82: 5594-5605.
    • (2008) J Virol , vol.82 , pp. 5594-5605
    • Schneidewind, A.1    Brockman, M.A.2    Sidney, J.3    Wang, Y.E.4    Chen, H.5


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