Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson's disease

Neuroscience

Volumn 232, Issue , 2013, Pages 90-105

  Lonskaya, I ^a   Hebron, M L ^a   Algarzae, N K ^a   Desforges, N ^a   Moussa, C E H ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Autophagy; Parkin; Parkinson disease; Striatum; Synuclein

Indexed keywords

ALPHA SYNUCLEIN; PARKIN; MAPT PROTEIN, RAT; TAU PROTEIN; UBIQUITIN PROTEIN LIGASE;

ADULT; AGED; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL FRACTIONATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FEMALE; GENE TRANSFER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LENTIVIRINAE; MALE; NIGRONEOSTRIATAL SYSTEM; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SOLUBILITY; SUBSTANTIA NIGRA PARS COMPACTA; VIRUS GENE; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL VACUOLE; CORPUS STRIATUM; GENETICS; MESENCEPHALON; METABOLISM; MIDDLE AGED; MUTATION; PARKINSONISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CORPUS STRIATUM; FEMALE; HUMANS; MALE; MESENCEPHALON; MIDDLE AGED; MUTATION; PARKINSONIAN DISORDERS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; TAU PROTEINS; UBIQUITIN-PROTEIN LIGASES; VACUOLES;

EID: 84872789246     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.12.018     Document Type: Article

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